In today's VETgirl online veterinary CE podcast, we review whether or not venous blood gas parameters (such as anion gap, base excess, lactate, etc.) predict survival in veterinary patients. When animals are initially presented to the emergency room, the extent of their condition often cannot be fully assessed without additional diagnostics. Is there a way we can handle questions from pet owners regarding the financial investment in their pet's medical treatment (such as prognosis and anticipated costs of medical care) based on evidence-based medicine? We strive to look for indicators in our physical examination findings and in our initial diagnostic work up (e.g., preliminary lab work or quick assessment tests) to help bolster our understanding of the patient's prognosis, but presently veterinary medicine is greatly lacking in these indicators of mortality and disease severity. In the veterinary emergency room, blood gases are a quick and easy piece of lab work that can be obtained relatively quickly at the time of triage for cats and dogs. So, Kohen et al out of University of California at Davis wanted to look at the information that can be obtained off a simple blood gas analysis for possible predictors of mortality. In this retrospective study, they looked at plasma lactate concentrations, pH, base deficit, and anion gap in both cats and dogs, and looked for any correlation of these values to an increased in mortality risk.