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Ascorbic acid is cytotoxic for pediatric tumor cells cultured in vitro. Related Articles
Sektion Onkologie/Immunologie, Universitäts Kinderklinik, Ruprecht-Karls-Universität, Heidelberg, Germany. Growth inhibition of neuroblastoma cells by lovastatin and
L-ascorbic acid is based on different mechanisms. [Cancer Lett.1999]
2 mM Ascorbic acid has a potent cytotoxic effect on neuroblastoma, osteosarcoma,
In vitro antitumor activity of rebeccamycin analog (NSC#
retinoblastoma, and rhabdomyosarcoma cells cultured in vitro. At a lower concentration (0.2
655649) against pediatric solid tumors. [JPediatrHematolOncol.1998]
mM), ascorbic acid remains highly cytotoxic for neuroblastoma, osteosarcoma and
retinoblastoma cells, but it has a stimulatory effect on the growth of rhabdomyosarcoma cells. Review Ascorbic acid and cancer.
[Subcell Biochem.1996]
PMID: 7703904 [PubMed - indexed for MEDLINE]
Review In vitro assays for chemotherapy sensitivity.
[Crit RevOncol Hematol.1993]
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