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1: Biochem Mol Biol Int. 1994 Nov;34(5):871-4.

Ascorbic acid is cytotoxic for pediatric tumor cells cultured in vitro. Related Articles

MGI 114: augmentation of antitumor activity when combined with


Medina MA, García de Veas R, Schweigerer L. topotecan. [JPediatrHematolOncol.2000]

Sektion Onkologie/Immunologie, Universitäts Kinderklinik, Ruprecht-Karls-Universität, Heidelberg, Germany. Growth inhibition of neuroblastoma cells by lovastatin and
L-ascorbic acid is based on different mechanisms. [Cancer Lett.1999]
2 mM Ascorbic acid has a potent cytotoxic effect on neuroblastoma, osteosarcoma,
In vitro antitumor activity of rebeccamycin analog (NSC#
retinoblastoma, and rhabdomyosarcoma cells cultured in vitro. At a lower concentration (0.2
655649) against pediatric solid tumors. [JPediatrHematolOncol.1998]
mM), ascorbic acid remains highly cytotoxic for neuroblastoma, osteosarcoma and
retinoblastoma cells, but it has a stimulatory effect on the growth of rhabdomyosarcoma cells. Review Ascorbic acid and cancer.
[Subcell Biochem.1996]
PMID: 7703904 [PubMed - indexed for MEDLINE]
Review In vitro assays for chemotherapy sensitivity.
[Crit RevOncol Hematol.1993]

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Patient Drug Information

Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...)


Ascorbic acid is used to prevent and treat scurvy, a disease
caused by a lack of vitamin C in the body.

Source: AHFS Consumer Medication Information

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