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METABOLISMO ES ANFIBLICO

CATABOLISMO

CONJUNTO DE VAS DEGRADATIVAS


SE OBTIENE ENERGA
ESTAS VAS METABOLICAS CONVERGEN EN
POCOS PRODUCTOS FINALES
ES OXIDATIVO
ANABOLISMO

CONJUNTO DE VAS BIOSINTETICAS


SE REQUIERE ENERGA
ESTAS VAS METABOLICAS DIVERGEN PARA
SINTETIZAR GRAN VARIEDAD DE BIOMOLCULAS
ES REDUCTIVO

DESTINOS DE LA GLUCOSA

( Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

GLUCLISIS
La glucosa (6C) y otros monosacridos son
degradados hasta piruvato (3C).
Parte de la energa libre liberada se conserva en
forma de ATP.
Tiene lugar en el citoplasma.
No interviene para nada el oxgeno molecular.

Reaccin Neta:
Glucosa + 2 ADP + 2 Pi + 2 NAD+ ---> 2 Piruvato + 2 ATP + 2 NADH + 2 H+ + 2 H2O

VISIN GENERAL DE
LA GLUCLISIS

ENERGIA
INVOLUCRADA EN
GLUCLISIS

FASES DE LA
GLUCLISIS

( Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

( Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Reacciones de la gluclisis
1.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

2.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

3.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

4.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

5.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

6.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

7.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

8.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

9.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

10.

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

DESTINOS DEL PIRUVATO

Fermentacin
Alcohlica

Respiracin Celular
Fermentacin
Lctica

FERMENTACIN LCTICA

Eritrocitos
Msculo esq. (ejercicio)

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

FEMENTACIN ALCHOLICA

Levaduras (pan, cerveza)


Bacterias

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

REGENERACIN DEL NAD EN CONDICIN ANAERBICA

METABOLISMO DE OTROS CARBOHIDRATOS

Lehninger Principles of Biochemistry 3th.ed.


Nelson, DL and Cox, M.M. Worth Publishers, 2000.)

METABOLISMO DE OTROS CARBOHIDRATOS


(resumen)

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