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    Fast Wound Healer

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
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    25 views6 pages

    Fast Wound Healer

    Uploaded by

    kwag
    Fast Wound Healer

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 6
    United States Patent 11» Danner et al. [54] ANTISEPTIC COMPOSITION AND PROC! FOR PROPHYLAXIS AND THERAPEUTIC TREATMENT OF DERMAL DISORDERS [75] Inventors: Bobby Hampar L. Karag Catistrano, Calis Fa Norman, Okla [73] Assignee: Bio-Cide International, Ine., Noman, Okla. [21] Appl. Nos $68,745 [22] Filed: Dee. 7, 1995 [51] Int. cle AGIK 3320 [52] US. Ch 424/668; 424/661; 14/858; 514/859; 514/860; 514/861: 514/862; 514/863; 514/864; 514/865; 514/028 [58] Field of Search 424/661, 662, 424/065; 514/858, 859, 860, 861, 862, 863, 864, 865, 928, [56] References Cited USS, PATENT DOCUMENTS. Re. 31,779 12/1984. Alliger 252/187. 2TOLTS1 2/1955. de Guevara 167/17 3271-212 9/1966 MeNicholas 167/17 ‘4084747 4/1978. Alliger 2394 431784 Lao ‘av130 4.330531 ‘Alliger 2410 4)507,285 5 Kuhne 424615 574,084 Berger 24/128 44689,215 Ratcitt 424/53, 4696811 9/1987 Ratelith 424/53, 4725437 2/1988 Kubne ‘24613 44,780,492. 11/1988 Rate 424/53, 4.788.053. 11/1988 Rateith 424/53, 4792442. 12/1988 Ratcliff 424/53, 4.793989 12/1988 Ratcliff 424/33, 4]808,389 2/1989 Rateife 424/53, 418519 4/1989 Rate 424153, 4837.09 6/1989. Racti 424/33, 4851213 7/1989 Rate 424/53, 5,855,922 Jan. 5, 1999 USO0S8: 59220 (1) Patent Number: [45] Date of Patent: 4.855135 8/1989 Rateltt 24127 4)880,638 11/1989 Gordon 4241662 891,216 1/1990 Kross eta. 2478 4.956184 9/1990 Kross “24/661 4.986.990 1/1901 Davidson etal 24/665 4.990.334 2/1991 Longino et. 424/401 5,019,402 5/1901 Kross eta 425/665 5.100652 3/1992. Krone etal 424/53, 5192459 3/1993 Tell eta 124/665 5384134 1/1905 Kross eta 424/601 SaI9SIS 5/1995 Wanngard 204/95 51623725 4/1997 Kross “24/665 FOREIGN PATENT DOCUMENTS 01265005 wo 8504107 101989 9/1985 Japan wi OTHER PUBLICATIONS Chemical Abstracts 115:129522, 1991 Meailine Abstract, accession No, 89190173, 1989. ‘Chemical Abstracts 102:137809, 1985, Primary Examiner—John Pak Attorney, Agent, or Firm-—Crow & Dunlevy 157] ABSTRACT ‘Compositions and processes for the prophylaxis and thera- peutic treatment of wounds, chronic non-healing wounds, burns, disease and other dermal disorders are disclosed, The compositions of the present invention comprise aqueous solutions of a metal chlorite having a concentration of from bout 0.002% to about 0.5% by weight of metal eblorite. The process of the present invention comprises weating the dermal disorder with an aqueous solution of from about 0,002% 10 about 0.5% by weight of a metal chlorite ‘Wounds, chronie non-healing wounds, buens andl other der- ‘mal disorders teated in this manner heal more quickly and with reduced scar formation. The antiseptic compositions ‘and processes of the present invention exhibit anticollag~ ‘enous activity such that the characteristics of the healed skin, such as elasticity and tensile strength, are similar to undam- aged skin 8 Claims, No Drawings 5,855,922 1 ANTISEPTIC COMPOSITION AND PROCESS FOR PROPHYLAXIS AND THERAPEUTIC ‘TREATMENT OF DERMAL DISORDERS BACKGROUND OF THE INVENTION 1. Field of the Invention ‘The present invention involves the treatment of dermal disorders, wounds and infections in humans and is more particularly directed toward compositions and! methods for the treatment and prophylaxis of dermal wounds, chronic non-healing wounds, burns, disease, and other dermal dis- onders. 2. Discussion ‘As human skin los its hair cover through the centuries, it underwent many adaptive changes which gave it strength and resilience. The outer layer, while remaining thin to allow ‘suppleness, attained remarkable biological ruggedness, pro- tecting the skin from physical and chemical injury and from the invasion of micro-onganisms. Human skin is elastic t0 accommodate size increases and decreases of the body it fencases and to accommodate the many subtle movements that characterize the human body. ‘Contiauously exposed to trauma, human skin has inherent mechanisms that enable it to adapt fo new situations and to ‘withstand the onslaught of injurious environmental condi tions. Skin repairs expertly and with dispatch the perennial ‘minor injuries it suffers and, given an opportunity, repairs ‘major injures as well. Many injuries to the skin, such as bums or cuts, however, result in healed skin that displays scarring as well as reduced elasticity, tensile strength and other characteristics, The scarred skin is not only less aesthetically appealing, but also less functional. “The surface of the skin is normally never sterile. At birth, ‘orsoon aftr, it becomes populated with germs, which all but the most stringent measures fail to remove. These patho- ‘genic microorganisms are ubiquitous and, as opportunistic parasites, usually become invasive and infectious when the body's normal barriers to infection are compromised. Examples of the compromise of dermal barriers include

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