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ALZHEIMER S DISEASE
Description Diagnosis Causes Risk Factors Symptoms Medications Updates
Description
most common form of dementia among older people progressive degenerative disease of the brain from which there is no recovery a person with AD loses all memory and mental functioning
Diagnosis
Medical History and Physical Examination Laboratory Tests Neuropsychological Tests Brain-Imaging Scans
Causes
At this time, only one gene, apolipoprotein E (ApoE) has been definitively linked to lateonset Alzheimer's disease head injuries in early adulthood and Alzheimer' s development. Lower educational level
Risk Factors
Age Gender Family History Heart and Vascular Diseases Lifestyle Factors
Symptoms
Memory changes that disrupt daily life Challenges in planning or solving problems Difficulty completing familiar tasks at home, at work, or at leisure Confusion about time or place Trouble understanding visual images and spatial relationships Language problems Misplacing things and losing the ability to retrace steps Impaired judgment and decision making Withdrawal from work or social activities Mood and personality changes
MEDICATION
Cholinesterase inhibitors (generally used to treat mild-to-moderate Alzheimer's; donepezil is also approved for treatment of severe dementia ) N-methyl-D-aspartate (NMDA) receptor antagonists (used to treat moderate-to-severe Alzheimer's)
Treatment
There is currently no cure for Alzheimer' s disease, or treatment to stop its progression or reverse the symptoms. Medications may help on a short-term basis (6 months to a few years) to slow cognitive decline. Various drug and nondrug treatments can help with behavioral symptoms, such as sleeplessness and agitation.