cefuroxime

Generic Name: cefuroxime (SEF ue ROX eem) Brand names: Ceftin, Kefurox, Zinacef, Zinacef ADD-Vantage
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What is cefuroxime?
Cefuroxime is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body. Cefuroxime is used to treat many kinds of bacterial infections, including severe or lifethreatening forms. Cefuroxime may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about cefuroxime?

Do not take this medication if you are allergic to cefuroxime, or to similar antibiotics, such as Cefzil, Keflex, Omnicef, and others. Before taking this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have liver or kidney disease, diabetes, a history of intestinal problems, or if you are malnourished. Cefuroxime can make birth control pills less effective, which may result in pregnancy. Tell your doctor if you are taking birth control pills to prevent pregnancy. You may need to use another form of birth control during treatment with cefuroxime. Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefuroxime will not treat a viral infection such as the common cold or flu. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using cefuroxime.

What should I discuss with my health care provider before taking cefuroxime?
Do not take this medication if you are allergic to cefuroxime, or to other cephalosporin antibiotics, such as: cefaclor (Raniclor); cefadroxil (Duricef); cefazolin (Ancef); cefdinir (Omnicef); cefditoren (Spectracef); cefpodoxime (Vantin); cefprozil (Cefzil); ceftibuten (Cedax); cephalexin (Keflex); or cephradine (Velosef). Before taking cefuroxime, tell your doctor if you are allergic to any drugs (especially penicillins), or if you have:

kidney disease; liver disease; a history of intestinal problems, such as colitis; diabetes; or if you are malnourished. If you have any of these conditions, you may need a dose adjustment or special tests to safely take cefuroxime. The oral suspension (liquid) form of cefuroxime may contain phenylalanine. Talk to your doctor before using this form of cefuroxime if you have phenylketonuria (PKU). FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Cefuroxime can make birth control pills less effective, which may result in pregnancy. Tell your doctor if you are taking birth control pills to prevent pregnancy. You may need to use another form of birth control during treatment with cefuroxime. Cefuroxime can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
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How should I take cefuroxime?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. You may take cefuroxime tablets with or without meals. Cefuroxime oral suspension (liquid) must be taken with food. Shake the oral liquid well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. If you switch from using the tablet form to using the oral suspension (liquid) form of cefuroxime, you may not need to use the same exact dosage in number of milligrams. The medication may not be as effective unless you use the exact form and strength your doctor has prescribed. Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefuroxime will not treat a viral infection such as the common cold or flu. This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using cefuroxime. Store cefuroxime tablets at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Store cefuroxime oral liquid in the refrigerator. Do not allow it to freeze. Throw away any unused medication that is older than 10 days.

What happens if I miss a dose?

Take the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (black-out or convulsions).

What should I avoid while taking cefuroxime?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Cefuroxime side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects: diarrhea that is watery or bloody; fever, chills, body aches, flu symptoms; chest pain, fast or pounding heartbeats; unusual bleeding; blood in your urine; seizure (convulsions); pale or yellowed skin, dark colored urine, fever, confusion or weakness; jaundice (yellowing of the skin or eyes); fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; skin rash, bruising, severe tingling, numbness, pain, muscle weakness; increased thirst, loss of appetite, swelling, weight gain, feeling short of breath; or painful or difficult urination, urinating less than usual or not at all. Less serious side effects may include:

nausea, vomiting, stomach pain, mild diarrhea, gas, upset stomach; cough, stuffy nose; stiff or tight muscles, muscle pain; joint pain or swelling; headache, drowsiness; feeling restless, irritable, or hyperactive; white patches or sores inside your mouth or on your lips; unusual or unpleasant taste in your mouth; diaper rash in an infant taking liquid cefuroxime; mild itching or skin rash; or vaginal itching or discharge. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Cefuroxime Dosing Information

Usual Adult Dose for Bronchitis: 250 to 500 mg orally twice a day or 750 mg to 1.5 grams IV or IM every 8 hours for 5 to 10 days Usual Adult Dose for Cystitis: Uncomplicated: 250 mg orally twice a day or 750 mg IV or IM every 8 hours for 7 to 10 days Usual Adult Dose for Epiglottitis: 1.5 g IV every 6 to 8 hours for 7 to 10 days, depending on the nature and severity of the infection Usual Adult Dose for Gonococcal Infection -- Disseminated: 750 mg to 1.5 g IV every 8 hours Parenteral therapy should be continued for 24 to 48 hours after clinical improvement is demonstrated. Oral therapy with cefixime or cefpodoxime may then be continued to complete a total course of at least 1 week. Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin (1 g) is also recommended to treat possible concurrent chlamydial infection. The patient's sexual partner(s) should also be evaluated/treated. Usual Adult Dose for Gonococcal Infection -- Uncomplicated: Uncomplicated infections of the cervix, urethra, or rectum: Oral: 1 g orally one time Intramuscular: 1.5 g IM (0.75 g administered in two separate sites) one time with 1 g probenecid orally Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin (1 g) is also recommended to treat possible concurrent chlamydial infection. The patient's sexual partner(s) should also be evaluated/treated. The Centers for Disease Control and Prevention suggest cefuroxime axetil may be effective as an oral alternative for the treatment of uncomplicated gonorrhea of the cervix, urethra, or rectum. Usual Adult Dose for Joint Infection:

1.5 g IV every 8 hours Therapy should be continued for approximately 3 to 4 weeks, depending on the nature and severity of the infection. Longer therapy, 6 weeks or more, may be required for prosthetic joint infections. In addition, removal of the involved prosthesis is usually required. Usual Adult Dose for Lyme Disease: 500 mg orally twice a day for 20 days The Infectious Diseases Society of America has recommended oral cefuroxime as an alternative to amoxicillin or doxycycline for the treatment of Lyme disease when oral therapy is appropriate (erythema chronicum migrans, cranial nerve palsy, first or second degree heart block, and arthritis). Febrile patients should also be evaluated/treated for human granulocytic ehrlichiosis (HGE) and babesiosis. Usual Adult Dose for Meningitis: 1.5 g IV every 6 hours or 3 g IV every 8 hours for 14 days Usual Adult Dose for Osteomyelitis: 1.5 g IV every 8 hours Therapy should be continued for approximately four to six weeks depending on the nature and severity of the infection. Chronic osteomyelitis may require an additional one to two months of oral antimicrobial therapy. Usual Adult Dose for Otitis Media: 250 mg orally twice a day for 10 days Usual Adult Dose for Peritonitis: 750 mg to 1.5 g IV every 8 hours for 10 to 14 days CAPD-associated peritonitis: 1 gram per 2 liters of dialysate intraperitoneally, followed by a continuous maintenance dosage of 150 to 400 mg per 2 liters of dialysate Usual Adult Dose for Pneumonia: Uncomplicated: 750 mg IV or IM every 8 hours Complicated: 1.5 g IV or IM every 8 hours Once the patient responds clinically to parenteral therapy, cefuroxime 250 mg to 500 mg orally every 8 hours for 7 to 21 days may be administered. Duration of therapy is dependent upon the suspected causative organism's sensitivity to cefuroxime.

Usual Adult Dose for Pyelonephritis: 750 mg to 1.5 g every 8 hours or 250 to 500 mg orally twice a day for 14 days, depending on the nature and severity of the infection Usual Adult Dose for Sepsis: 1.5 g IV every 6 to 8 hours, in combination with an aminoglycoside Therapy should be continued for 7 to 21 days depending on the nature and severity of the infection. Usual Adult Dose for Sinusitis: 250 mg orally twice a day for 10 to 14 days Usual Adult Dose for Skin or Soft Tissue Infection: 250 to 500 mg orally twice a day (uncomplicated infections) or 750 mg IV every 8 hours for 10 days Usual Adult Dose for Surgical Prophylaxis: Preoperative: 1.5 g IV 30 to 60 minutes before the initial incision Postoperative: 750 mg IV or IM every 8 hours when the procedure is prolonged Open heart surgery: 1.5 g IV at induction and every 12 hours thereafter for a total of 6 g Cefuroxime prophylaxis is recommended as alternative to cefazolin for cardiothoracic surgery, heart transplantation, and lung or heart-lung transplantation. Cefazolin is considered the drug of choice in clean operations because it is active against Staphylococcus aureus and S epidermidis, has a long duration of action, and is relatively inexpensive. Alternatively, vancomycin may be indicated in patients with severe beta-lactam hypersensitivity or for major surgeries at institutions with high rates of MRSA or MRSE infections. Usual Adult Dose for Tonsillitis/Pharyngitis: 250 mg orally twice a day for 10 days Usual Adult Dose for Upper Respiratory Tract Infection: 250 to 500 mg orally twice a day Usual Adult Dose for Urinary Tract Infection: Uncomplicated: 250 mg orally twice a day for 7 to 10 days or 750 mg IV every 8 hours Complicated: 1.5 g IV every 8 hours

Usual Pediatric Dose for Epiglottitis: 3 months to 12 years: 50 to 100 mg/kg/day IV in divided doses every 6 to 8 hours (maximum 6 g/day) for 7 to 10 days, depending on the nature and severity of the infection Usual Pediatric Dose for Joint Infection: 3 months to 12 years: 50 mg/kg IV every 8 hours (maximum 6 g/day) 13 years or older: Adult dose Usual Pediatric Dose for Osteomyelitis: 3 months to 12 years: 50 mg/kg IV every 8 hours (maximum 6 g/day) 13 years or older: Adult dose Usual Pediatric Dose for Meningitis: 3 months to 12 years: 200 mg to 240 mg/kg/day IV in divided doses every 6 to 8 hours (maximum 9 g/day) 13 years or older: Adult dose Usual Pediatric Dose for Otitis Media: 3 months to 12 years: 250 mg tablet orally twice a day for 10 days or 15 mg/kg of the suspension twice a day for 10 days; maximum daily dose is 1000 mg 13 years or older: Adult dose Usual Pediatric Dose for Sinusitis: 3 months to 12 years: 250 mg tablet orally twice a day for 10 days or 15 mg/kg of the suspension orally twice a day for 10 to 14 days; maximum daily dose is 1000 mg 13 years or older: Adult dose Usual Pediatric Dose for Skin and Structure Infection: 3 months to 12 years: 15 mg/kg of the suspension orally twice a day for 10 days; maximum daily dose is 1000 mg Usual Pediatric Dose for Impetigo: 3 months to 12 years: 15 mg/kg of the suspension orally twice a day for 10 days; maximum daily dose is 1000 mg Usual Pediatric Dose for Tonsillitis/Pharyngitis:

3 months to 12 years: 10 mg/kg of the suspension twice a day for 10 days; maximum daily dose is 500 mg 13 years or older: Adult dose Usual Pediatric Dose for Bacterial Infection: 3 months to 12 years: Parenteral: 50 to 100 mg/kg/day IV or IM in divided doses every 6 to 8 hours (maximum daily dose 6 g), depending on the nature and severity of the infection Oral: Suspension: 10 to 15 mg/kg orally twice a day (maximum dose 1000 mg/day) Tablets: 250 mg orally twice a day 13 years or older: Adult dose

What other drugs will affect cefuroxime?

Before taking cefuroxime, tell your doctor if you are taking any of the following drugs:

probenecid (Benemid); a blood thinner such as warfarin (Coumadin); a medication that reduces stomach acid, such as an antacid, or cimetidine (Tagamet), famotidine (Pepcid), omeprazole (Prilosec), ranitidine (Zantac), and others; or a diuretic (water pill) such as bumetanide (Bumex), furosemide (Lasix), indapamide (Lozol), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), metolazone (Mykrox, Zarxolyn), spironolactone (Aldactazide, Aldactone), torsemide (Demadex), and others. This list is not complete and there may be other drugs that can interact with cefuroxime. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start taking a new medication without telling your doctor.

Cefuroxime
(se fyoor ox' eem)
Last reviewed: October 1, 2010.

U.S. National Library of Medicine National Institutes of Health

Why is this medication prescribed?

Cefuroxime is used to treat certain infections caused by bacteria, such as bronchitis; gonorrhea; Lyme disease; and infections of the ears, throat, sinuses, urinary tract, and skin. Cefuroxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections.

How should this medicine be used?

Cefuroxime comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours (twice a day) for 7-10 days. To treat gonorrhea, cefuroxime is taken as a single dose, and to treat Lyme disease, cefuroxime is taken twice a day for 20 days. The tablet may be taken with or without food, and the liquid must be taken with food. To help you remember to take cefuroxime, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefuroxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well before each use to mix the medication evenly. The tablets should be swallowed whole and taken with a full glass of water. Because the crushed tablet has a strong bitter taste, the tablet should not be crushed. Children who cannot swallow the tablet whole should take the liquid instead. Take cefuroxime until you finish the prescription, even if you feel better. Stopping cefuroxime too soon may cause bacteria to become resistant to antibiotics.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cefuroxime,

tell your doctor and pharmacist if you are allergic to cefuroxime, penicillin, cefaclor (Ceclor), cefadroxil (Duricef), cefamandole (Mandol), cefazolin (Ancef, Kefzol), cefdinir (Omnicef), cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefmetazole (Zefazone), cefonicid (Monocid), cefoperazone (Cefobid), cefotaxime (Claforan), cefoxitin (Mefoxin), cefpodoxime (Vantin), cefprozil (Cefzil), ceftazidime (Ceptaz, Fortaz, Tazicef), ceftibuten (Cedax), ceftizoxime (Cefizox), ceftriaxone (Rocephin), cephalexin (Keflex), cephapirin (Cefadyl), cephradine (Velosef), loracarbef (Lorabid), or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin), diuretics ('water pills'), medications for heartburn or ulcers, other antibiotics, and probenecid (Benemid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had kidney or liver disease, colitis, or stomach problems. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefuroxime, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefuroxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

upset stomach vomiting diarrhea stomach pain

If you experience any of the following symptoms, call your doctor immediately:

severe skin rash itching hives difficulty breathing or swallowing wheezing diaper rash painful sores in the mouth or throat vaginal itching and discharge

Cefuroxime may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [athttp://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Keep liquid medicine at room temperature or in the refrigerator, tightly closed, and throw away any unused medication after 10 days. Do not freeze. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:

seizures

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cefuroxime. If you are diabetic, use Clinistix or TesTape (not Clinitest) to test your urine for sugar while taking this medication. Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the cefuroxime, call your doctor. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

GENERIC NAME: cefuroxime BRAND NAME: Ceftin

DRUG CLASS AND MECHANISM: Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. It is effective against a wide variety of bacteria organisms, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhoeae, and many others. PRESCRIPTION: yes GENERIC AVAILABLE: yes PREPARATIONS: Tablets: 125 mg, 250 mg, 500 mg. Suspension: 125 mg per 5 ml teaspoon. STORAGE: Tablets should be stored at room temperature in a tightly closed container. The oral suspension should be stored in the refrigerator in a tightly closed container. PRESCRIBED FOR: Cefuroxime is effective against susceptible bacterias causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, andpneumonia. It is also used in treating urinary tract infections, skin infections, and gonorrhea. Additionally, it is useful in treating acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD). DOSING: Should be taken with food. DRUG INTERACTIONS: Cefuroxime should be avoided by patients with a knownallergy to cephalosporin type antibiotics. Since cefuroxime is chemically related to penicillin, an occasional patient can have an allergic reaction (sometimes evenanaphylaxis) to both medications. Treatment with cefuroxime and other

antibiotics can alter the normal bacteria flora of the colon and permit overgrowth of C. difficile, a bacteria responsible for pseudomembranous colitis. Patients who develop pseudomembranous colitis as a result of antibiotics treatment can experiencediarrhea, abdominal pain, fever, and sometimes even shock. Probenecid may increase the blood levels of cefuroxime. Cefuroxime can be used by children. It is not habit forming. SIDE EFFECTS: Cefuroxime is generally well tolerated and side effects are usually transient. Reported side effects include diarrhea, nausea, vomiting, abdominal pain,headache, rash, hives, vaginitis, headache, and mouth ulcers. Certain cephalosporins, including cefuroxime axetil (Ceftin)can alter the colon's normal bacteria, leading to overgrowth of a bacterium called Clostridium difficile.Overgrowth ofthis bacterium leads to therelease of toxinsthat contribute to the development of Clostridium difficile-associated diarrhea, which may range in severity from mild diarrhea to fatal colitis.

GENERIC NAME: CEFUROXIME - ORAL (seff-you-ROX-eem) BRAND NAME(S): Ceftin

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes |Missed Dose | Storage USES: Cefuroxime is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. HOW TO USE: Take this medication by mouth usually twice daily, or as directed by your doctor. Take cefuroxime with food to increase absorption and reduce stomach upset. Dosage is based on your medical condition and response to therapy.Swallow the tablets whole. Do not crush or chew because the tablets have a strong bitter taste. Use the liquid suspension form of this medication if it is difficult to swallow the tablets.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.Continue to take this medication until the fullprescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens. SIDE EFFECTS: Nausea, vomiting, diarrhea, or stomach pain may occur.Dizziness and drowsiness may occur less frequently, especially with higher doses. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual tiredness/weakness.Tell your doctor immediately if any of these rare but very serious side effects occur: yellowing of the eyes/skin, severe stomach/abdominal pain, persistent nausea/vomiting, dark urine, change in the amount of urine, signs of new infection (e.g., fever, persistent sore throat), easy bruising/bleeding, jerky movements, chest pain, mental/mood changes (such as confusion).This medication may rarely cause a severe intestinal condition (Clostridium difficileassociated diarrhea) due to a resistant bacteria. This condition may occur while receiving therapy or even weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain

medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

cefuroxime - oral, Ceftin (cont.)

PRECAUTIONS: Before taking cefuroxime, tell your doctor or pharmacist if you are allergic to it; or to penicillins or other cephalosporin antibiotics (e.g., cephalexin); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, intestinal disease (colitis), liver disease, poor nutrition.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects.This medication should be used only when clearly needed duringpregnancy. Discuss the risk and benefits with your doctor.This medication passes into breast milk. Consult your doctor before breast-feeding. DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: "blood thinners" (e.g., warfarin), live bacterial vaccines, probenecid.This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.This medication may affect the results of certain lab tests. It may cause false positive results with certain diabetic urine testing products (cupric sulfate-type) and false negative results with certain blood glucose tests. Make sure laboratory personnel and your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.