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Sleep Staging Basics

Copyright 2006 Compumedics Ltd.

The following presentation is being provided for informational and educational purposes only. While Compumedics endeavors to ensure the validity and accuracy of the information within, we cannot be held responsible for inaccuracies, opinions or practices that often vary between various experts or are without established acceptable medical standards. Please consult your own medical director for clarification or for policies that are specific to your facility. We welcome your comments, suggestions and corrections. Please e-mail your comments to: marketing@compumedics.com.au

Copyright 2006 Compumedics Ltd.

Sleep Staging Variables


Electroencephalogram (EEG) - acquired by surface electrodes on the scalp at standardized locations (10-20 system) Electrooculogram (EOG) - acquired by surface electrodes placed at the outer canthus of each eye Electromyogram (EMG) - acquired by surface electrodes placed on the chin muscle (sub-mental)

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Sleep Staging Channels

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EEG
Frequency and amplitude change with sleep stage: Wake: high frequency Stage 1, REM: low amplitude, mixed frequency, vertex waves Stage 2: spindles, k-complexes Stage 3/4: delta waves Standard sleep epoch is 30 seconds

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EOG
EOG records voltage changes caused by eye movement; EOG changes with sleep stage Wake: random, high amplitude:

Stage 1: slow rolling:

REM: very flat with occasional rapid eye movements:

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EMG
Recorded as the potential between two surface electrodes placed several centimeters apart Typically, the chin (submental) muscle is used because it exhibits large differences during sleep, aiding in the identification of stages Wake - high activity Sleep - lower activity REM sleep - paralysis of skeletal muscles

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Sleep Stage Criteria


Awake
Alpha or faster > 50% of epoch Many eye movements High EMG
ALPHA WAVES

THETA WAVES

Stage 1
Alpha or faster < 50 % of epoch Increasing theta activity Slow rolling eyes Vertex sharp waves
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VERTEX WAVE

Sleep Staging Criteria


Stage 2
Sleep Spindles
12-14 cps 0.5 second duration or longer Sleep Spindle

and/or K-complexes
Sharp negative deflection followed by nearly equal positive deflection At least 0.5 seconds in duration

K-complex

< 3 minutes apart


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Sleep Staging Criteria


Stage 3 - Delta Waves (75uV) 20-50% of epoch Stage 4 - Delta > 50 % of epoch
DELTA WAVES

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Sleep Staging Criteria


REM
Lowest EMG Rapid Eye Movements (REMs) Spindles or K-complexes > 3 minutes apart Saw-tooth EEG Low-amplitude, mixed frequency EEG similar to stage 1

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Stage: Awake

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Stage 1 Sleep

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Stage 2 Sleep

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Stage 3 Sleep

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Stage 4 Sleep

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Stage REM Sleep

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Stage REM Sleep

Sawtooth waveform pattern seen in REM sleep.


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Infant Sleep Patterns


Circadian rhythm not established prior to week 10 or 11 from birth. Consolidation of sleep usually occurs by week 16-17. Between 24-36 weeks Active-Quiet Sleep pattern is established. At 5-6 months R&K rules can be applied. Age is corrected for normal gestational age.

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Changing Sleep Patterns With Age

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Active Sleep - Infant


Continuous cycling of wakefulness-active sleep (REM) and quiet sleep(NREM). Sleep onset is usually to active sleep (REM) Mixed, low-voltage, irregular EEG Suppressed EMG Intermittent REMs Frequent muscle twitches and body movements

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Active Sleep - Infant

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Quiet Sleep - Infant


High voltage, slow-wave EEG activity Trace alternant, 3-8 sec. burst of high voltage slow waves, alternating with 4-8 seconds of low voltage mixed freq. waves EMG tonic Eye movements absent Minimal body movement

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Quiet Sleep - Infant

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Infant Sleep Staging


Wake, Active (REM) Sleep, Quiet (NREM) Sleep, Indeterminate, Movement or Artifact. If an epoch can not be staged as Wake, Active or Quiet, it is Indeterminate. Crying is considered awake. Artifact is scored if one minute or more of recording is unscorable.

Copyright 2006 Compumedics Ltd.

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