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Mitochondrial DNA Replication - essentially a modification of bacterial theta replication that forms catenanes (however it is a continuously replicating system- Why?)
Sigma replication: How many circular phage particles rapidly replicate their DNA (can be single- or doublestranded molecules) (From Genes VIII)
Phage strategies II: Three different ways of priming during replication of the minus strand
Looped rolling circle replication: How a single stranded circular phage that has formed the minus (-) strand can end DNA synthesis andregenerate its plus (+) strand
This table is less than 10 years old and look at the paucity of DNA polymerases as compared to Table 8.2 in your text; there has literally been an entirely new group of eukaryotic DNA polymerases discovered, the TLS repair polymerases
Combined Pol/primase product is ~ 50-100 bp Low processivity Further extension by Pol or Pol is between 100 and 10,000 bp Fig. 8.16
Without the PCNA clamp the polymerase would dissociate and diffuse away from the template about every 20-100 bases
Fig. 8.18
Probably a more realistic approximation of the eukaryotic replication fork and replisome structure
Entire set of cis-acting sequences that is sufficient to direct initiation of replication (the origin is part of replicator)
Initiating Replication: The Replicon Model (Jacob, Brenner and Cuzin) and its implications for starting replication
Fig. 8.23
Fig. 8.25
B1 and A bind to initiator ORC; B2 facilitates unwinding and binding of other factors
GATCTNTTNTTTT Unwinding