I.

Experiment title : Preparation of Iodoform

II. Experiment Date : Friday, 22 March 2013
III.Experiment objective : At the end of the experiment, students are expected to :
a. Synthesized iodoform compound
b. Iodoform purify by recrystallization
IV. Basic Theory
Iodoform is the organoiodine compound with the formula CHI
3
. A pale yellow,
crystalline, volatile substance, it has a penetrating odor (in older chemistry texts, the smell
is sometimes referred to as the smell of hospitals) and, analogous to chloroform, sweetish
taste. It is occasionally used as a disinfectant. It is also known as tri-iodomethane, and
sometimes also referred to as carbon triiodide (which is not strictly correct, as this
compound also contains hydrogen) or methyl triiodide (which is somewhat ambiguous as
that name could also refer to the methylated triiodide ion, CH
3
I
3
).
Iodoform is a compound formed from the reaction of iodine with ethanol / acetone and
acetaldehyde in alkaline conditions. Preparation of Iodoform similar to the manufacture of
chloroform, as an analog its iodin. However, in contrast to the manufacture of chloroform.
In making iodoform reagent used is sodium hipoiodit. The reaction occurs between
carbonyl compound which has an acetyl group (CH
3
CO
-
) and sodium hipoidoit (NaOI).
The color of Iodoform crystal obtained in the form of yellow, with a melting point of
120
0
C and has a characteristic odor. Iodoform can be used as a disinfectant and antiseptic
outside. Haloform Iodoform reaction is a reaction in which iodide is used in the reaction of
alkali hydroxide solution (NaOH and KOH) to produce Iodoform. The equation is
expressed as follow:









O

O

R C CH
3
+ 3 NaOH R C Cl
3
+ 3 NaOH
O

O

R C Cl
3
+ NaOH R C ONa + CHI
3

Sodium alkanoat salt Iodoform
Secondary alcohol such as ethanol can be oxidized so as to from acetaldehyde it can
maked iodoform when treated with sodium hipoidit.








Iodoform has uses as the destruction of bacteria iodoform is used as an antiseptic to
the wounds abrasions, as it frees I
2.
And iodoform as a deterrent preventing discharge of
pus and bacteria growth.

V. Tools and Materials
A. Tools
200 mL Erlenmeyer
Graduated cylinder
Buchner Funnels
Funnel
Electric stove
Filter paper
Spatula

B. Material
Iodoform
Acetone
2 N NaOH
Alcohol
aquades









O

O

R CH CH
3
+ NaOI R C CH
3
+ NaI + H
2
O
O

O

R C CH
3
+ 3NaOI R C ONa + CHI
3
+ 2NaOH
Sodium alkanoat salt Iodoform
V.Procedure

































Determined the mass and melting
point
Cooled
Added 12,5 ml of aquades
Filter by using Buchner Funnel
Wash with some drops od cold
ethanol
Dried iodoform crystal using
desicator
Entered into erlenmeyer 200ml
Added 2,5 mL of acetone
Added 5 mL of aquades
Shaked
Added NaOH 2N solution drop by drops,
and shaked until formed yellow precitate
Shake until form yellow precipitate
Added 125 ml aquades
Filtered using buchner funnel
2,5 gram Iodium
Put into erlenmeyer flask that has been
closed with glass funnel
Put 5 ml ethanol from the funnel (keep
away from flame)
Heated and shaked
Filtered
Washed the precipitate with
water until free from NaOH
Filtrate Residu
Iodoform Impurities
Residu Filtrate
The mass of
iodoform
Crystal of Iodoform
The melting point
of iodoform

VIII. Refference
Anonim.http://id.wikipedia.org/wiki/iodoform. Excessed on the 20
th
March 2013
Fessenden RJ. Fessenden JS. 1991. Kimia Organic, Edisi ketiga terjemahan A. Harayana
Dudjaatrata, Jilid 1 dan 2. Jakarta: Penerbit Erlangga.
Tim Dosen Kimia Organik. 2012. Panduan Praktikum Kimia Organik I. Surabaya :
jurusan kimia FMIPA UNESA.