MERUPAKAN SINDROMA KLINIK YANG TERDIRI DARI SESAK NAFAS DAN
RASA CEPAT LELAH YANG DISEBABKAN OLEH KELAINAN JANTUNG. KLASIFIKASI FUNGSIONAL GAGAL JANTUNG (NYHA 1. TIMBUL GEJALA SESAK NAFAS ATAU CAPAI PADA KEADAAN FISIK YANG BERAT 2. TIMBUL GEJALA PADA KEGIATAN FISIK YANG SEDANG 3. TIMBUL GEJALA PADA KEGIATAN FISIK YANG RINGAN 4. TIMBUL GEJALA PADA KEGIATAN FISIK YANG SANGAT RINGAN DAN PADA WAKTU ISTIRAHAT 5. SEBAB GAGAL JANTUNG PENYAKIT JANTUNG KORONER DAN PASCA IMA HIPERTENSI PENYAKIT KATUB JANTUNG KARDIOMIOPATI SERTA MIOKARDITIS PENYAKIT JANTUNG BAWAAN PENYAKIT PARU KRONIS CPC Clinical Manifestations Symptoms The cardinal symptoms of HF are fatigue and shortness of breath. Although fatigue has been traditionally ascribed to the low cardiac output in HF, it is likely that skeletalmuscle abnormalities and other noncardiac comorbidities !e.g., anemia" also contribute to this symptom. #n the early stages of HF, dyspnea is obser$ed only during e%ertion& howe$er, as the disease progresses, dyspnea occurs with less strenuous acti$ity, and ultimately may occur e$en at rest. The origin of dyspnea in HF is likely multifactorial !Chap. ''". The most important mechanism is pulmonary congestion with accumulation of interstitial or intraal$eolar fluid, which acti$ates (u%tacapillary ) receptors, which in turn stimulate rapid, shallow breathing characteristic of cardiac dyspnea. *ther factors that contribute to dyspnea on e%ertion include reductions in pulmonary compliance, increased airway resistance, respiratory muscle and+or diaphragm fatigue, and anemia. ,yspnea may become less fre-uent with the onset of right $entricular !./" failure and tricuspid regurgitation. *rthopnea *rthopnea, which is defined as dyspnea occurring in the recumbent position, is usually a later manifestation of HF than is e%ertional dyspnea. #t results from the redistribution of fluid from the splanchnic circulation and lower e%tremities into the central circulation during recumbency, with a resultant increase in pulmonary capillary pressure. 0octurnal cough is a fre-uent manifestation of this process and a fre-uently o$erlooked symptom of HF. *rthopnea is generally relie$ed by sitting upright or by sleeping with additional pillows. Although orthopnea is a relati$ely specific symptom of HF, it may occur in patients with abdominal obesity or ascites and in patients with pulmonary disease whose lung mechanics fa$or an upright posture. 1aro%ysmal 0octurnal ,yspnea !10," This term refers to acute episodes of se$ere shortness of breath and coughing that generally occur at night and awaken the patient from sleep, usually 23' h after the patient retires. 10, may be manifest by coughing or whee4ing, possibly because of increased pressure in the bronchial arteries leading to airway compression, along with interstitial pulmonary edema leading to increased airway resistance. 5hereas orthopnea may be relie$ed by sitting upright at the side of the bed with the legs in a dependent position, patients with 10, often ha$e persistent coughing and whee4ing e$en after they ha$e assumed the upright position. Cardiac asthma is closely related to 10,, is characteri4ed by whee4ing secondary to bronchospasm, and must be differentiated from primary asthma and pulmonary causes of whee4ing. CheyneStokes .espiration Also referred to as periodic respiration or cyclic respiration, CheyneStokes respiration is common in ad$anced HF and is usually associated with low cardiac output. CheyneStokes respiration is caused by a diminished sensiti$ity of the respiratory center to arterial 1 C*6 . There is an apneic phase, during which the arterial 1 *6 falls and the arterial 1 C*6 rises. These changes in the arterial blood gas content stimulate the depressed respiratory center, resulting in hyper$entilation and hypocapnia, followed in turn by recurrence of apnea. CheyneStokes respirations may be percei$ed by the patient or the patient7s family as se$ere dyspnea or as a transient cessation of breathing. Acute 1ulmonary 8dema See Chap. 699. *ther Symptoms 1atients with HF may also present with gastrointestinal symptoms. Anore%ia, nausea, and early satiety associated with abdominal pain and fullness are fre-uent complaints and may be related to edema of the bowel wall and+or a congested li$er. Congestion of the li$er and stretching of its capsule may lead to rightupper -uadrant pain. Cerebral symptoms, such as confusion, disorientation, and sleep and mood disturbances, may be obser$ed in patients with se$ere HF, particularly elderly patients with cerebral arteriosclerosis and reduced cerebral perfusion. 0octuria is common in HF and may contribute to insomnia. 1hysical 8%amination A careful physical e%amination is always warranted in the e$aluation of patients with HF. The purpose of the e%amination is to help determine the cause of HF, as well as to assess the se$erity of the syndrome. *btaining additional information about the hemodynamic profile and the response to therapy and determining the prognosis are important additional goals of the physical e%amination. :eneral Appearance and /ital Signs #n mild or moderately se$ere HF, the patient appears in no distress at rest, e%cept for feeling uncomfortable when lying flat for more than a few minutes. #n more se$ere HF, the patient must sit upright, may ha$e labored breathing, and may not be able to finish a sentence because of shortness of breath. Systolic blood pressure may be normal or high in early HF, but it is generally reduced in ad$anced HF because of se$ere ;/ dysfunction. The pulse pressure may be diminished, reflecting a reduction in stroke $olume. Sinus tachycardia is a nonspecific sign caused by increased adrenergic acti$ity. 1eripheral $asoconstriction leading to cool peripheral e%tremities and cyanosis of the lips and nail beds is also caused by e%cessi$e adrenergic acti$ity. )ugular /eins !See also Chap. 66<" 8%amination of the (ugular $eins pro$ides an estimation of right atrial pressure. The (ugular $enous pressure is best appreciated with the patient lying recumbent, with the head tilted at =>?. The (ugular $enous pressure should be -uantified in centimeters of water !normal @ cm" by estimating the height of the $enous column of blood abo$e the sternal angle in cm and then adding > cm. #n the early stages of HF, the $enous pressure may be normal at rest but may become abnormally ele$ated with sustained !A2 min" pressure on the abdomen !positi$e abdomino(ugular reflu%". :iant v wa$es indicate the presence of tricuspid regurgitation. 1ulmonary 8%amination 1ulmonary crackles !rales or crepitations" result from the transudation of fluid from the intra$ascular space into the al$eoli. #n patients with pulmonary edema, rales may be heard widely o$er both lung fields and may be accompanied by e%piratory whee4ing !cardiac asthma". 5hen present in patients without concomitant lung disease, rales are specific for HF. #mportantly, rales are fre-uently absent in patients with chronic HF, e$en when ;/ filling pressures are ele$ated, because of increased lymphatic drainage of al$eolar fluid. 1leural effusions result from the ele$ation of pleural capillary pressure and the resulting transudation of fluid into the pleural ca$ities. Since the pleural $eins drain into both the systemic and pulmonary $eins, pleural effusions occur most commonly with bi$entricular failure. Although pleural effusions are often bilateral in HF, when unilateral they occur more fre-uently in the right pleural space. Cardiac 8%amination 8%amination of the heart, although essential, fre-uently does not pro$ide useful information about the se$erity of HF. #f cardiomegaly is present, the point of ma%imal impulse !1M#" is usually displaced below the fifth intercostal space and+or lateral to the midcla$icular line, and the impulse is palpable o$er two interspaces. Se$ere ;/ hypertrophy leads to a sustained 1M#. #n some patients, a third heart sound !S ' " is audible and palpable at the ape%. 1atients with enlarged or hypertrophied right $entricles may ha$e a sustained and prolonged left parasternal impulse e%tending throughout systole. An S ' !or protodiastolic gallop" is most commonly present in patients with $olume o$erload who ha$e tachycardia and tachypnea, and it often signifies se$ere hemodynamic compromise. A fourth heart sound !S = " is not a specific indicator of HF but is usually present in patients with diastolic dysfunction. The murmurs of mitral and tricuspid regurgitation are fre-uently present in patients with ad$anced HF. Abdomen and 8%tremities Hepatomegaly is an important sign in patients with HF. 5hen present, the enlarged li$er is fre-uently tender and may pulsate during systole if tricuspid regurgitation is present. Ascites, a late sign, occurs as a conse-uence of increased pressure in the hepatic $eins and the $eins draining the peritoneum. )aundice, also a late finding in HF, results from impairment of hepatic function secondary to hepatic congestion and hepatocellular hypo%ia, and is associated with ele$ations of both direct and indirect bilirubin. 1eripheral edema is a cardinal manifestation of HF, but it is nonspecific and usually absent in patients who ha$e been treated ade-uately with diuretics. 1eripheral edema is usually symmetric and dependent in HF and occurs predominantly in the ankles and pretibial region in ambulatory patients. #n bedridden patients, edema may be found in the sacral area !presacral edema" and the scrotum. ;ongstanding edema may be associated with indurated and pigmented skin. Cardiac Cache%ia 5ith se$ere chronic HF, there may be marked weight loss and cache%ia. Although the mechanism of cache%ia is not entirely understood, it is likely multifactorial and includes ele$ation of the resting metabolic rate& anore%ia, nausea, and $omiting due to congesti$e hepatomegaly and abdominal fullness& ele$ation of circulating concentrations of cytokines such as T0F& and impairment of intestinal absorption due to congestion of the intestinal $eins. 5hen present, cache%ia augers a poor o$erall prognosis. Keluhan waktu kencing atau perubahan pada kencing a. disuria B adalah rasa tidak enak yang bisa berupa rasa nyeri atau panas pada waktu kencing. Ciasanya disebabkan oleh adanya infeksi pada bulibuli !cystitis" atau uretra !urethritis". b. Stranguria B adalah rasa amat nyeri pada waktu kencing dan kencing yang dikeluarkan hanya beberapa etes. #ni bisa disebabkan oleh infeksi berat pada buli buli. c. frekuensi B yaitu meningkatnya frekuensi kencing sehingga penderita kencing berkalikali melebihi kebiasaan normalnya. d. 0okturia B yaitu bila penderita bangun pada malam hari untuk buang air kecil sampai beberapa kali. #ni bisa disebabkan oleh #SD atau pembesaran prostat. Perubahan jumlah kencing a. poliuria B bila $olume total urin meningkat !E' l+6= (am". 1enyebabnya antara lain karena adanya gangguan mekanisme konsentrasi urin atau karena (umlah air yang diminum berlebihan. b. *ligouri B yaitu bila $olume total urin F=<< ml+6= (am. #ni merupakan tanda dari gagal gin(al. c. anuria B yaitu bila $olume total urin F2<< ml+6= (am. Ciasanya disebabkan oleh obstruksi ureter bilateral, atau karena adanya oklusi aorta atau a. .enalis bilateral !Gogiantoro, et al, 6<<H". Etiologi CKD ,iabetes melitus Hipertensi :lomerulonefritis *bstruksi dan infeksi Dista 1enyakit sistemik !S;8, $askulitis" 0eoplasma
Pericoronitis Is Defined As The Inflammation of The Soft Tissues of Varying Severity Around An Erupting or Partially Erupted Tooth With Breach of The Follicle