Course CLP 5354-01 Cognitive Neuroscience

Instructors Daniel Krawczyk, Ph.D.

Term Fall 2009
Day / Time Thur 2-5pm

Instructor’s Contact Information

Office Phone 972-883-3234
Other Phone 972-883-4474
Office Location Center for BrainHealth 3rd floor (see receptionist at main desk on 1st floor)
Email Address Daniel.krawczyk@utdallas.edu
Office Hours Thursday 12:30-1:30 or by appointment
Other Information

General Course Information

Pre-requisites, Co-
requisites, & other none
restrictions
Course Description
This course provides an overview of how the field of cognitive
neuroscience is currently interfacing with clinically relevant research.
The course will cover current methods of cognitive neuroscience and
how they are used to gather information about the relationship between
the mind and the nervous system in both healthy states and in disease
states. The main textbook will be Cognitive Neuroscience: The Biology
of the Mind by Gazzaniga, Ivry, and Mangun 3rd ed. Additional assigned
readings will be provided via pdf the week before they are to be
discussed. Students are encouraged to be active participants in class
discussions.

Students will:
• Be able to critically assess papers relating to cognitive neuroscience
and functional MRI
• Be able to assess disorders in psychiatrically impaired individuals
based on these methods
• Discuss critically experimental design in studies of healthy
individuals, disease-relevant studies and functional neuroimaging
Learning Outcomes studies of cognition
• Recognize and differentiate among fundamental concepts in both
cognition and neuroscience of clinically relevant phenomena
• Incorporate research design principles from clinically relevant
studies into experiments as well as recognize the relevance of basic
cognitive neuroscience to clinically relevant states

Gazzaniga, M., Ivry, R., & Mangun, G. (2009). Cognitive Neuroscience:

The biology of the mind 3rd Edition, W.W. Norton and
Company, NY.
Required Texts,
Journal Articles & Additional papers will be distributed via email in pdf format before they
other Materials are to be discussed.
Students are strongly encouraged to do the assigned readings before
coming to each class.
 Suggested Texts,
Readings, Journal
Articles & Materials

Assignments & Academic Calendar

[Topics, Reading Assignments, Due Dates, Exam Dates]
Date Topics Readings Assignments
Aug. Introduction and Course Ch. 1 (Gazzaniga
27 Information text)
General Overview of
Cognitive Neuroscience
Sept. 3 Operations of the Ch. 2 (Gazzaniga
Nervous System (Cell text)
Physiology)
Sept. Neuroanatomy Ch. 3 (Gazzaniga
10 text)
Sept. Visual Perception Ch 5. (177-203) Gobbini N.I. & Haxby, J. Neural response
17 Ch. 6 (Gazzaniga to the visual familiarity of faces. Brain Res
text) Bull. 2006 Dec 11;71(1-3):76-82.

Sachdev P, Mondraty N, Wen W, Gulliford

K. Brains of anorexia nervosa patients
process self-images differently from non-
self-images: an fMRI study.
Neuropsychologia. 2008;46(8):2161-8.

Sept Learning and Memory Ch. 8 (Gazzaniga Maguire EA, Woollett K, Spiers HJ.
24 text) London taxi drivers and bus drivers: a
structural MRI and neuropsychological
analysis. Hippocampus. 2006;16(12):1091-
101.

Cannon, TD, Glahn, DC., Kim, J. et al.

Dorsolateral prefrontal cortex activity
during maintenance and manipulation of
information in working memory in patients
with schizophrenia. Arch Gen Psychiatry.
2005 Oct;62(10):1071-80.

Oct 1 Emotion Ch. 9 (Gazzaniga Bechara, A., Damasio, H., Damasio, AR.
Emotion, decision making and the
orbitofrontal cortex. Cereb Cortex. 2000
Mar;10(3):295-307.

Deeley Q, Daly EM, Surguladze S, et al. An

event related functional magnetic resonance
imaging study of facial emotion processing
in asperger syndrome. Biol Psychiatry.
2007 Aug 1;62(3):207-17.

Oct 8 Language Ch. 10 (Gazzaniga Yang, F. G., Edens, J., Simpson, C., &
text) Krawczyk, D. C. (in press). Differences in
task demands influence the hemispheric
lateralization and neural correlates of
metaphor. Brain and Language.
 Kircher TT, Leube DT, Erb M, Grodd W,
Rapp AM. Neural correlates of metaphor
processing in schizophrenia. Neuroimage.
2007 Jan 1;34(1):281-9.

Oct 15 Cerebral laterality and Ch. 11 (Gazzaniga Wolford G, Miller MB, Gazzaniga M.
specialization text) The left hemisphere's role in hypothesis
formation. J Neurosci. 2000 Mar
15;20(6):RC64.

Miller MB, Valsangkar-Smyth M, Newman

S, Dumont H, Wolford G.Brain activations
associated with probability matching.
Neuropsychologia. 2005;43(11):1598-608.

Saxe R, Wexler A. 2005. Making sense of

another mind: the role of the right temporo-
parietal junction. Neuropsychologia.
43:1391-1399.

Oct. 22 Attention and Ch. 12 (Gazzaniga Eddy MD, Schnyer D, Schmid A, Holcomb
Consciousness text) PJ. Spatial dynamics of masked picture
repetition effects. Neuroimage. 2007 Feb
15;34(4):1723-32.

Childress AR, Ehrman RN, Wang Z, Li Y,

Sciortino N, Hakun J, Jens W, Suh J,
Listerud J, Marquez K, Franklin T,
Langleben D, Detre J, O'Brien CP. Prelude
to passion: limbic activation by "unseen"
drug and sexual cues. PLoS ONE. 2008 Jan
30;3(1):e1506.

Oct. 29 Control of Action Ch. 7 (Gazzaniga Wei G, Luo J. Sport expert's motor imagery:
text) Functional imaging of professional motor
skills and simple motor skills.Brain Res.
2009 Aug 14. [Epub ahead of print]

Mataix-Cols D, Wooderson S, Lawrence N,

Brammer MJ, Speckens A, Phillips
ML.Distinct neural correlates of washing,
checking, and hoarding symptom
dimensions in obsessive-compulsive
disorder. Arch Gen Psychiatry. 2004
Jun;61(6):564-76.

Nov. 5 NO CLASS

Nov. Cognitive Control Ch. 13 (Gazzaniga Baym CL, Corbett BA, Wright SB, Bunge
12 text) SA. Neural correlates of tic severity and
cognitive control in children with Tourette
syndrome. Brain. 2008 131(Pt 1):165-79.
 Pliszka SR, Glahn DC et al. Neuroimaging
of inhibitory control areas in children with
attention deficit hyperactivity disorder who
were treatment naive or in long-term
treatment. Am J Psychiatry. 2006

Nov. Social Cognition Ch. 14 (Gazzaniga Andersen, SW et al. Impairment of social

19 text) and moral behavior related to early damage
in human prefrontal cortex. Nat Neurosci.
1999 Nov;2(11):1032-7.

Russell TA, Schmidt U, Doherty L, Young V,

Tchanturia K. Aspects of social cognition in
anorexia nervosa: affective and cognitive
theory of mind. Psychiatry Res. 2009 Aug
15;168(3):181-5.

Nov. No Class - Thanksgiving

26
Dec. 3 Evolutionary Perspectives Ch. 15 (Gazzaniga Stone, V., Cosmides, L., Tooby, J., Kroll, N.
text) & Knight, R. (2002). Selective Impairment
of Reasoning About Social Exchange in a
Patient with Bilateral Limbic System
Damage. Proceedings of the National
Academy of Sciences. (August, 2002).

Flemming TM, Beran MJ, Thompson RK,

Kleider HM, Washburn DA. What meaning
means for same and different: Analogical
reasoning in humans (Homo sapiens),
chimpanzees (Pan troglodytes), and rhesus
monkeys (Macaca mulatta). J Comp
Psychol. 2008 May;122(2):176-85.

Dec. Future of Clinical Leibenluft E. Skating to where the puck will

10 Neurscience - Final be: the importance of neuroimaging literacy
Discussion in child psychiatry . J Am Acad Child
Adolesc Psychiatry. 2008 Nov;47(11):1213-
6.

Marsh R, Gerber AJ, Peterson BS.

Neuroimaging studies of normal brain
development and their relevance for
understanding childhood neuropsychiatric
disorders.J Am Acad Child Adolesc
Psychiatry. 2008 Nov;47(11):1233-51.
Course Policies
Grading (credit) Grading Criteria
Criteria
Make-up Exams NA
Extra Credit NA
Late Work NA
Each student will be responsible for two presentations made with partners
Special throughout the semester. This will be assigned early on in the semester.
Assignments Additionally, students are expected to be prepared to discuss readings at the
class period
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