Professional Documents
Culture Documents
Literature Review
Proposals
Manuscripts
LITERATURE REVIEW
Goals
To conduct a comprehensive search
using pre-defined search strategy
To identify all relevant published work
To prepare quality review for thesis,
proposal, manuscript
Steps
Sources
Published reports
Sources
Search Terms
Search
Search
Online
From library
From colleagues
Summarize Articles
Responsible Conduct
Disregard Syndrome*
Plagiarism
Plagiarism
Questionable practice?
Re-work someones idea without giving
credit
Copy a paragraph verbatim preceded by
___ found the following results.
Misconduct
PROPOSALS
Proposal
To portray
Your good ideas
Logic and suitability of design, methods,
and analysis
Contribution to advancement of
scientific knowledge, public good, or
aims of a company
Anatomy of a Proposal
Title
Abstract
Budget
Investigators
Resources
Research plan
Bibliography
Specific aims
Literature review
[Preliminary studies]
methods
attract readers
Research goals
Importance of work
Key words and term
Conform to guidelines
Titles
Examples
1R03AG15197 BRAND, RICHARD
DOES OSTEOPOROSIS ALTER BONE
CELL RESPONSE TO STRAIN?
5P01AG05793 BURR, DAVID
EFFECT OF SUPPRESSED BONE
TURNOVER ON SKELETAL FRAGILITY
Taken from NIH CRISP database
Abstract or Summary
Abstract Instructions
Abstract
Try to include:
Rationale/background
2-4 sentences
2-4 sentences
Proposed methods
<=5 sentences
Abstract
Research Plan
Purpose: To portray
What do you intend to do?
Why is it important?
Significance/Rationale/Background
Specific Aims
Specific Aims
Background
Background
Composition
Write for informed reader but not expert
Use strong topic sentences
Pull out topic sentences should tell entire story
reading
Neat
White space
12 point font
Proofread to avoid
Typographical errors
Incomplete sentences
Incorrect citations
Inconsistent headings, font
Successful Proposals
MANUSCRIPTS
Examples of Scientific
Publications
Theses
Abstracts
Reviews
Letters to Editors
Case reports
Newsletter and newspaper articles
Journal articles (peer reviewed)
First disclosure
Scope
Readership
Length limitation
Impact factor
Impact Factor
Impact Factor
Impact Factor
Examples (2001)
Cell
Nature
Ann Intern Med
J Bone Min Res
J Biomech
29.2
28.0
11.1
6.2
1.9
Title page
Abstract and key
words
Introduction
Methods
Results
Discussion
Acknowledgment
References
Tables
Figure legends
Figures
Title
Purpose
Forms
Phrase
Statement
Question - rare
Title: Examples
Transplantation 2003]
Abstract
State
Rationale
Basic methods
Main findings
Main conclusions
Introduction
Zeiger, M:
Writing Biomedical
Research Papers
Introduction
Introduction
Statement of aims
Examples:
To determine
Therefore, the objective of this study was
To test the hypothesis that , the following
study was
Introduction
Verb tense
First person
Optional
Length
Approximately 5 paragraphs
Methods
Methods
Organize chronologically
Report in past tense
Use figures only if add substantial
information
Illustrations of equipment
Flow charts of protocol
Results
Results
Goals:
To display data with visual object
(efficient)
To encourage viewer to compare
different sets, see relationships
Graphs
Graphs
Fractured
Augmented
Direct injection
Reduction + injection
Graphs
Outcome Variable
Group A
Group B
Graphs
7000
6000
5000
4000
3000
2000
1000
0.00
0.50
1.00
1.50
Graphs
Treated
0.7
0.65
0.6
Control
0.55
0.5
0
Time (years)
Graphs
0.7
0.6
0.5
0.4
0.3
0.2
0.1
Time (years)
Results: Statistics
Actual p values
Results: Organization
Discussion
Main goals:
To show that an answer to the research
question has been obtained
To discuss how this answer fits with
previous work
To fully disclose restrictions to
interpretation
Discussion
Acknowledgment
State:
Contributors
Sources of support
Conflicts of interest or dual commitments
References
Resources