SYLLABUS

HUMAN GENETICS, BIO 1318, Fall, 2005, MC 2.410 (TR 9:30-10:45)

Textbook: Essential Genetics: A Genomics Perspective, 4th ed., by Hartl & Lewis, 2006*

Instructor: Dr. Lee Bulla (FN3.112), 972.883.4226, lee.bulla@utdallas.edu

Office hours: Tue & Thur 11:00-12:00

Teaching Assistant: Dr. A. Dixit, and044000@utdallas.edu

Genetics is the study of biologically inherited traits. Each species of living organisms is united by a common set of inherited
traits, observable characteristics that set it apart from all other species of organisms. In this course, we will address three major
questions. What is the chemical nature of the genetic material? How is the genetic material transmitted? And what does it do?
These questions will be examined and discussed from a genomics perspective.

Five exams will be given throughout the semester. The final grade will be based on the average of four of the five exams. No
make-up exam will be given for absence from an exam other than for official university business or illness (both require
either a written university authorization or a physician’s statement). All hand-held electronic devices, including cell
phones, must be stored away during exams. Lecture outlines will be posted on the course web site. It is fully expected that
students will attend and participate in the lectures and discussions.

LECTURE SCHEDULE
LECTURE DATE TOPIC CHAPTER
1 18 Aug The Genetic Code of Genes and Genomes 1
2 23 Aug Transmission Genetics: Heritage from Mendel - 1 2
3 25 Aug Transmission Genetics: Heritage from Mendel - 2 2
4 30 Aug The Chromosomal Basis of Heredity - 1 3
5 1 Sep The Chromosomal Basis of Heredity - 2 3
6 Sep EXAM 1 1, 2, & 3
6 8 Sep Human Chromosomes and Chromosome Behavior 5
7 13 Sep DNA Structure, Replication and Manipulation - 1 6
8 15 Sep DNA Structure, Replication and Manipulation - 2 6
9 20 Sep DNA Structure, Replication and Manipulation - 3 6
22 Sep EXAM 2 5&6
10 27 Sep The Molecular Genetics of Gene Expression - 1 8
11 29 Sep The Molecular Genetics of Gene Expression - 2 8
12 4 Oct Molecular Mechanisms of Gene Regulation -1 9
13 6 Oct Molecular Mechanisms of Gene Regulation - 2 9
Review for Exam 3
11 Oct EXAM 3 8&9
14 13 Oct Genomics, Proteomics and Genetic Engineering - 2 10
15 18 Oct Genomics, Proteomics and Genetic Engineering - 2 10
16 20 Oct The Genetic Control of Development - 1 11
17 25 Oct The Genetic Control of Development - 2 11
18 27 Oct Molecular Mechanisms of Mutation and DNA Repair 12
1 Nov EXAM 4 10, 11 & 12
19 3 Nov Molecular Genetics of the Cell Cycle and Cancer -1 13
20 8 Nov Molecular Genetics of the Cell Cycle and Cancer - 2 13
21 10 Nov Molecular Evolution and Population Genetics - 1 14
22 15 Nov Molecular Evolution and Population Genetics -2 14
23 17 Nov The Genetic Basis of Complex Inheritance 15
22 Nov EXAM 5 13, 14 & 15