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DESIRED OUTCOME: Improved blood glucose control in individuals with Type II Diabetes

Proposed constituent
Chromium
Gymnema
Bittermelon

Type of Evidence
Human RCT,
Observational,
Intervention
1 human study,
Lots of animal
Human trials,
animal, in vitro

Dose
200 1000 g
200 400 mg
100 g/day (food)

lipoic acid

2 human RCT,
4 in vitro

600 mg
300 1200 mg

Cinnamon

3 human trials
Lot of rat

1 6 g (powdered)

Indication
Hypoglycemic agent,
hyperlipidemia
(Look at alt med review monograph on
pub med)

Glucose management,
peripheral neuropathy,
macular degeneration
(preliminary vision
support)
blood glucose, HDL,
TG, cholesterol

DESIRED OUTCOME: Benefit to symptoms of BPH, Reduce risk of prostate cancer, Improve outcome
in prostate cancer.

Proposed constituent
Saw palmetto

Type of Evidence
1 meta-analysis,
Human intervention

Dose
85-95% FA plant
sterols, 320 mg/day
at least 3 months

Lycopene (need to cook

tomato to make
bioavailable)

5 human clinical
trials, 1 rat study

2 cups sauce, cooked

tomatoes (whole std.
tom. to lycopene), 1 can
tomato paste,
encapsulated GMO
tomato extract

Pau Darco

In vitro, animals, 1
human (n=9)

1:2 ratio fluid

extract tincture,
5-10 ml

Nettle

Human DB RCT
(620ppl over 6
months)

Vitamin E

Human

Selenium

3 human

Plant sterols

2 review, 4 RCT-DB

Pygeum Africanum
Exercise / Weight Loss

Clinical
intervention, metaanalysis, 18 human
Observational
studies

Indication
Moderate BPH Sx
Tomato - tumor, PSA,
CA
Lycopene nothing!

Used for cancer/chemo

May have RISK associated
with use.
flow rate, urinary
4000 6000 mg/day retention, use in BPH,
safe, no SE
(75 IU) RDA = 15 IU,
50 mg tocopherol
(Std 400-800 IU)
1 mg = 1.5 IU
200 g/day (selenized
yeast 5-10% Se)

32% incidence of CA
41% rate of death from
prostate CA

500 mg 3x/day CHOL,

300 mg/day prostate CA

BPH

75 200 mg

BPH Sx

2 -3 hrs/week
(walking)

risk of CA

63% prostate CA (LU,

LIV)

DESIRED OUTCOME: Stabilize and / or improve mood in depression prone individuals or individuals
with depression. Symptomatic improvement for symptoms of anxiety.

Proposed constituent
Fish Oil
St. Johns Wort
5 HTP

Type of Evidence

Human trials, decent

900 1800 mg
efficacy
300 mg/day,
DB Clinical Trials,
900mg/day wt loss
meta analysis
(anorexicagent)

Tryptophan (in turkey and

pumpkin)
Glycine
Passionflower

Dose
1000 mg of EPA

2000 4000 mg/day

Powder / capsule
2000 mg (put
directly under your
tongue)
Know that it is used in depression / anxiety
Instantaneous
conversion to
GABA in the brain

Valarian

1 study (no placebo)

Combo w/ St Johns
more effective,
100mg/day up to
900mg/day
(standardizations)

Zinc

1 human trial

25 mg/day

Indication
SE, as good as drugs
Anxiety, mood, Sx,
efficacy = modest
Banned eosinophillia
myalgia syndrome
Calms you down, relaxes

Insomnia (sleep aid)

not for long term use

40% reduction in anxiety