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Fact Sheet for the SNIFFER Framework

Basic model information Brief model description

Model name: Framework for Deriving Numeric The SNIFFER Framework (the Framework) is a paper-
Targets to Minimise the Adverse based risk assessment tool for deriving site-specific
Human Health Effects of Long-term assessment criteria (SSAC) [1]. This Framework
Exposure to Contaminants in Soil provides a deterministic methodology for deriving
(April 2000) human health assessment criteria for chronic exposure
to contaminants in soil, and does not evaluate impacts
Available from: Foundation for Water Research from contaminated groundwater or surface water
Allen House, The Listons, Liston Road, receptors. The assessment criteria are defined as
Marlow, Bucks SL7 1FD contaminant levels in soils that minimise risks to
Tel: 01628 891589 Fax: 01628 472711 human health. The Framework contains a series of
equations that allow the user to derive these
www.fwr.org site-specific assessment criteria.

Cost: £35 per copy A set of worksheets containing simplified formulae for
generic land uses (e.g. residential, commercial) are
Developed by: Scotland and Northern Ireland Forum provided. There are also worksheets for metals and
for Environmental Research (SNIFFER) metalloids, and organic compounds. Lead and cyanide
under contract to Land Quality are considered to be special cases due to their
Management Ltd. toxicological mode of action, and separate worksheets
Technical Report SR 99 (02) have been produced for the calculation of numeric
targets for these substances.
Model Update: At the time of publishing this fact
sheet, this version of the SNIFFER The Framework provides the majority of the data
Framework was being updated. Once required for implementation of the equations, and thus
finalised, the updated version will be can be used to derive site-specific assessment criteria.
available on the SNIFFER website at
www.sniffer.org.uk

Hardware: Calculator, pen/pencil

Fact Sheet No. FS-01 February 2003 Environment Agency Fact sheet for the SNIFFER framework 1
The Framework does not provide default values for site Land-use and exposure scenarios
conditions, physico-chemical parameters or
toxicological data. The user is required to select these The standard land uses considered in the SNIFFER
inputs from site investigation data and reliable Framework are:
information sources, where appropriate. All input
• residential with gardens
parameters must be fully justified.
• residential without gardens
Contaminants and contaminated media • commercial/industrial
• parks, playing fields and open spaces
The SNIFFER Framework only considers contaminated
• allotments
soil. The primary contaminants that can be evaluated
with this methodology are grouped into: Four soil exposure pathways are included in the
SNIFFER Framework. These pathways only relate to soil
• metals (except lead)
contamination. The exposure pathways included are:
• lead
• direct ingestion of soil and soil-derived dust
• cyanide
• consumption of home-grown vegetables
• organics (e.g. chlorinated solvents, hydrocarbons)
• outdoor inhalation of organic vapours
The Framework itself does not contain any type of • indoor inhalation of organic vapours
database regarding toxicological or physico-chemical
data for the above contaminants. Therefore, the user Dermal contact and inhalation of fugitive dust
needs to obtain this information from an appropriate exposure pathways are omitted.
(preferably UK-based) source.
Model outputs
Receptor types
A completed worksheet(s) is produced for each
The receptors included in the Framework are:
identified contaminant. Also, a risk characterisation
• children section should be completed providing justification for
• adults all the input parameters and a description of the
uncertainties associated with the assessment. See
Figure 1 SNIFFER worksheet Figure 1 for an example of the paper-based output.

Environment Agency Fact sheet for the SNIFFER framework 2


Key features of the model evaluated separately due to their toxicological mode of
action.

What the model is supposed to do (model utility) Lead

The SNIFFER Framework allows the user to derive As much more data and knowledge is available relating
human health based assessment criteria which the to lead and human exposure to it, the approach to
Framework refers to as “integrated reference target deriving numeric targets for lead in soil is different
concentrations”. These concentrations can then be from that for other metals. The approach does not use
used to support risk assessment and management a tolerable daily intake (TDI) but uses a blood lead
decisions on a site. level as the toxicity benchmark.

The SNIFFER Framework is a deterministic framework. Under the SNIFFER Framework it is not considered
This means that it uses a single value for each realistic to set stringent soil targets for lead because
exposure parameter and contaminant concentration. background exposure to non-soil sources of lead may
be high and represent a major contribution to lead
Model usability uptake, particularly for children. The numeric target for
soil lead should be proportional to the contribution
The Framework is implemented through the use of that soil lead makes to total lead uptake.
worksheets (Figure 1).
A 1–2 year old child is considered as the critical
The user is prompted to obtain and input a series of receptor. The SNIFFER Framework recommends default
parameters into blank boxes within the worksheets. values for the toxicology parameters required in the
The worksheets are simple to use as long as the user lead worksheet. Biokinetic models are used to describe
has some understanding of how some of the the relationship between lead uptake and equilibrated
parameter values (e.g. toxicological and exposure blood lead in children. However, in the absence of
parameters) are derived. Although easy to use, the validated studies on the empirical relationship between
model requires an intermediate level of competency in soil lead and blood lead (known as the ‘delta value’) a
risk assessment. Erroneous “integrated reference target default value may be used to estimate this biokinetic
concentrations” may be calculated if inappropriate parameter. The Framework recommends a default
parameter values are input into the model. value for delta in the absence of a site-specific value.

One advantage of the model is that it allows for an Cyanide


audit trail which can be examined if calculated values
appear to be wrong or as part of the on-going quality The cyanide worksheet is only applicable for acute
assurance and control measures inherent in any risk ingestion of free and complexed cyanides. It does not
assessment work. evaluate chronic inhalation of cyanides.

Toxicological information For inorganic cyanides acute rather than chronic


exposure is considered. This is because of the steep
The SNIFFER Framework does not provide defaults for dose response curve for acute exposure to cyanide.
toxicological data. Users need to identify and select The critical receptor is the small child (18 month old).
suitable tolerable daily intakes (TDIs) and adult mean The Framework suggests default values for the
daily intakes (AMDIs) by the oral and inhalation routes toxicological parameters and the one time soil
from an appropriate source. Appropriate sources ingestion rate.
include the Department of Health (DoH), Joint
FAO\WHO Expert Committee on Food Additives Receptor characterisation
(JECFA) etc. and the Defra / Environment Agency
documents CLR9 and TOX1-10 [2 and 3]. The choice For the SNIFFER Framework the critical receptor is the
of toxicological data used must be justified. human adult female although, as detailed above, the
critical receptors for lead and cyanide are the 1–2 year
Contaminants and contact media old and the 18 month old child exposed daily,
respectively.
The SNIFFER Framework only allows for the calculation
of contaminant exposure via soil and vapour media. The model uses 70 years as the averaging time for
The vapour media is evaluated only for volatile organic cancer endpoints but for non-cancer endpoints,
contaminants (VOCs). Therefore, soil vapours of averaging times differ depending on land use as
inorganic contaminants, such as elemental mercury, follows:
are not included within this assessment.
• 6 years for the residential with and without gardens,
Separate worksheets are included for the evaluation of parks, playing fields and open spaces land uses
cyanide and lead. These two contaminants are
Environment Agency Fact sheet for the SNIFFER framework 3
• 70 years for tÏhe allotment land use Pathway characterisation
• 43 years for the commercial/industrial land use
(16–59 year working life) The exposure routes included in the Framework are:
• direct ingestion of soil and soil-derived dust
The body weight or time-averaged body weight
(TABW) of the exposed receptor is calculated based on • consumption of home-grown vegetables
the receptor exposure duration (see Table 1). The • outdoor inhalation of organic vapours
default exposure durations are based on the selected • indoor inhalation of organic vapours
land use (see Table 2).
Intake via dermal contact and inhalation of inorganic
Table 1 Exposure duration and body weight
volatiles and fugitive dust are omitted from this
Framework. It is also important to note that exposure
Exposure duration (years) TABW (kg) from groundwater and surface water is omitted.

0–6 13.6
Model outputs
0–30 43.3
0–70 53.9 The output is a site-specific assessment criteria which is
described in the Framework as a “Level 1 numeric
16–59 61
target” (i.e. the concentration of contaminant in soil at
Table 2 Exposure duration for cancer and non-cancer
which adverse effects on human health from long-term
assessment and for different types of land use exposure are minimised). The observed representative
site concentration of contaminant may then be
Land use Cancer Non-cancer assessed against this numeric target.
endpoint endpoint
exposure exposure
duration duration
It is essential that the site-specific assessment criteria
(years) (years) (or numeric target) be placed into context by
conducting a comprehensive risk characterisation. This
Residential with gardens 0 – 30 0–6
should be supplied with the completed worksheet(s).
Residential without gardens 0 – 30 0–6 This characterisation should provide details of all
Parks, playing fields and sources of information and a justification for values
open spaces 0 – 70 0–6 selected for the parameters used in the calculations.
Allotments 0 – 70 0 – 70

Commercial/industrial 16 – 59 16 – 59
Model interpretation
The amount of ingested soil and inhalation of
contaminants in air are based on land use and What does the output mean?
toxicological endpoints (i.e. cancer or non-cancer
endpoints). The primary output is an integrated “reference target
concentration” (RTC) from each worksheet and for
Similarly, the amount of ingested contaminant via each contaminant evaluated. The generated RTC
vegetable ingestion is also based on land use and requires explanation and justification. The user does
toxicological endpoint. this during the risk characterisation stage where
justifications for the input parameters are discussed.
Land use
The risk characterisation stage requires the user to
There is no default land use within this model, compile a summary report containing as a minimum
therefore a land use must be selected when using this the following information:
Framework. The residential with gardens scenario is
• site use (current and intended)
the most critical land use of the SNIFFER Framework,
and the most conservative. • critical receptor
• choice of TDI and AMDI
The user is asked to select a site allocation factor (SAF) • pathways included and omitted, stating whether the
based on the land use being assessed and any user has considered the significance of the dermal
background exposure. This factor takes into account pathway
the fact that receptors can be exposed to the same
• soil parameters (e.g. percentage soil organic matter
on-site contaminants when off-site (i.e. soils from the
and pH)
neighbourhood). The SAF is used to ensure that if
receptors are exposed to contaminants similar to those • choice of site allocation factor (SAF)
found at the site from other sources they would still be An assessment without this information cannot be
protected by the derived integrated reference considered complete.
concentration.
Environment Agency Fact sheet for the SNIFFER framework 4
Supporting information required to use the Model limitations – what the model does not do
model appropriately (input data requirements)
The Framework cannot be applied to:
To implement the Framework the user needs to obtain • groundwater or surface water exposure
the following types of information: • asbestos
• present or future land use • radioactive substances
• tolerable daily intake (TDI) for each contaminant • metallic mercury
suitable for use in the UK context • intake of fugitive dust
• adult mean daily intake (AMDI) • inhalation of inorganic vapours
• receptor type (i.e. adult or child (with age) • dermal exposure
• exposure duration • free product
• site allocation factor (SAF) • organic substances with a high degree of dermal
• physico-chemical parameters for organic penetration.
contaminants
• source area Sensitive model parameters
• soil matrix physical parameters.
A sensitivity analysis of the SNIFFER Framework has
been produced [4] and is available to download from
Common problems with the model
the Scottish Environmental Protection Agency (SEPA)
website (www.sepa.org.uk/contaminated-
• This Framework does not contain a database of
land/links/sensitivity.pdf).
available contaminant toxicity values. This means that
the user needs to search for available toxicity values,
This sensitivity analysis was undertaken to determine
which can be time consuming. Appropriate sources
the effects of varying the input parameters and default
of toxicity values include the Department of Health
assumptions on the pathway-specific numeric targets
(DoH), Joint FAO / WHO Expert Committee on Food
and on the overall numeric target. The results of the
Additives (JECFA) etc. and Defra / Environment
sensitivity analysis can be used to demonstrate which
Agency documents CLR9 and TOX1-10 [2 and 3].
parameters need to be focused on when undertaking
• The Framework only allows the evaluation of one site investigations.
contaminant at a time. Therefore, many worksheets
would be required for a site with numerous Factors that are important and which could highly
contaminants. influence the result of the assessment are:
• SAF – If the factor selected is not representative of the
Common mistakes made when using the model
site scenario then it may neglect to account for the
• Mathematical errors receptor’s background exposure from other non-site
sources and result in an artificially high RTC.
• Using the wrong units for TDI or AMDI Therefore, the allowable site contaminant
• Erroneous use of the vegetable uptake algorithms concentration would be higher than otherwise
• Using the Framework when dermal exposure is advisable
important (e.g. when polychlorinated biphenyls are • TDI – If an unsuitable TDI is selected then the overall
present) integrated RTC may be calculated to be too high or
• Not including the completed worksheets as part of too low
the risk assessment • AMDI – If an artificially low AMDI is selected, then
• Including spreadsheets which have not been the overall integrated RTC may be too high and not
validated as the risk assessment effective in protecting the receptor.
• Not including an appropriate risk characterisation
section within the risk assessment.

The user must remember that this model evaluates


each contaminant separately. Therefore, additive and
synergistic effects are not evaluated as part of this
Framework. If the user considers these types of effects
important then they should seek appropriate expert
advice.

Environment Agency Fact sheet for the SNIFFER framework 5


References and further information

[1] SNIFFER (2000). Framework for Deriving Numeric


Targets to Minimise the Adverse Human Health
Effects of Long-term Exposure to Contaminants in
Soil. Prepared by Land Quality Management Ltd.
and published by Foundation for Water Research
(FWR), Marlow.
[2] Defra and the Environment Agency (2002)
Contaminants in Soil: Collation of Toxicological Data
and Intake Values for Humans. Report CLR9.
Published by Defra and the Environment Agency.
Available from WRc, Frankland Road, Swindon
Wilts SN5 8YF. Also downloadable from the Defra
website – www.defra.gov.uk.
[3] Defra and the Environment Agency (2002)
Toxicological Reports for Individual Soil
Contaminants. Report TOX1-10. Published by
Defra and the Environment Agency. Available from
WRc, Frankland Road, Swindon Wilts SN5 8YF. Also
downloadable from the Defra website –
www.defra.gov.uk.
[4] SNIFFER (2000). Sensitivity analysis of SNIFFER
Framework for deriving numeric targets to minimise
the adverse human health effects of long term
exposure to contaminants in soil. Prepared by Land
Quality Management Ltd. and published by
Foundation for Water Research (FWR), Marlow.

Further information

Further details on the application of this model and


other risk assessment models can be obtained from the
Environment Agency, National Groundwater and
Contaminated Land Centre (NGWCLC), Olton Court,
10 Warwick Road, Olton, Solihull, B92 7HX
Tel: 0121 7084714 Fax: 0121 7084637.

Acknowledgements

The National Groundwater and Contaminated Land


Centre would like to acknowledge and thank those
individuals who reviewed and commented on drafts of
this fact sheet. These reviewers included the model
developer, SEPA, the Environment Agency and
environmental consultants.

ISBN 1844320995

Environment Agency Fact sheet for the SNIFFER framework 6

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