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Chapter
3
The Molecules of Life
Objectives: To learn
How (milk) lactose intolerance can be treated?
Figure 3.4-1
OH
Monomer
Short polymer
Dehydration
reaction
H2O
Longer polymer
(a) Building a polymer chain
Figure 3.4-2
H2O
Hydrolysis
OH
Carbohydrates
Contain C, H, O
Empirical formula is: CnH2nOn
Simple sugars are known as monosaccharides
Examples include glucose, galactose, fructose
Out of the above three, fructose (fruit sugar) is the
sweetest
2016 Pearson Education, Inc.
Figure 3.5
Glucose
C6H12O6
Fructose
C6H12O6
Isomers
(same formula, different arrangements)
Figure 3.6
Figure 3.8
processed to extract
Starch
broken down into
Glucose
converted via enzyme to sweeter
Fructose
added to foods as
high-fructose corn syrup
Functions of Carbohydrates ?
Functions of Carbohydrates
Provide energy
Are important components of Nucleic acids
(DNA/RNA)
Component of cell membranes
Maintain cell shape/structure (e.g. Cellulose of
plant cell walls)
2016 Pearson Education, Inc.
Figure 3.0-2
Disaccharides
Linked by glycosidic bonds b/w monosaccharides
Examples:
Sucrose = Glucose + Fructose
Maltose = Glucose + Glucose
Milk Lactose = Glucose + Galactose
2016 Pearson Education, Inc.
Figure 3.7
OH
Galactose
Glucose
H2O
Lactose
Polysaccharides
Cellulose
is the most abundant organic compound on Earth,
forms cable-like fibrils in the walls that enclose plant
cells, and
cannot be broken by any enzyme produced by
animals.
Biostoning of jeans
using the enzyme
cellulase!
Levi Strauss
Cellulase enzyme is
used to
biostone jeans
to give
desired colour/texture
in controlled manner.
The enzyme breaks
down cellulose, releasing
indigo dye in the process.
Lipids (Fats)
Large and nonpolar in general
Do not dissolve in water
No. of oxygen atoms lesser than in sugars
Three main types of lipids:
True fats (e.g., butter)
Phospholipids (membrane components)
Steroids (most hormones)
Figure 3.11
HO
Fatty acid
H2O
Glycerol
(a) A dehydration reaction linking a fatty acid to glycerol
Figure 3.12
TYPES OF FATS
Saturated Fats
Unsaturated Fats
Margarine
Plant oils
Trans fats
Omega-3 fats
Phospholipids
Amphipathic in nature.
Important component
of cell membranes.
Steroids
Structure contains interlocking rings of
carbon.
Component of membranes (e.g. cholesterol).
Component of hormones (e.g. Testosterone,
estrogen).
Figure 3.13
Cholesterol
Testosterone
can be converted
by the body to
A type of estrogen
Synthetic anabolic
steroids, prescribed
for cancer/AIDS,
may be abused by
athletes to build
quick muscles.
Alex Rodriguez
Mark McGwire
Floyd Landis
Ben Johnson
Thought Question:
Why do animals living in cold temperatures
have higher proportions of PUFA in their
body lipids?
BIO F111
Objectives
How could Mr. V.K. Bansal (Bansal Classes) help
change the face of Kota (Rajasthan)?
Figure 3.15
Storage Proteins
(provide amino
acids for growth)
Contractile
Proteins
(help movement)
Transport Proteins
(help transport
substances)
Enzymes
(help chemical
reactions)
Figure 3.16-1
Amino
group
Carboxyl
group
Side
chain
(a) The general structure of an amino acid
Figure 3.16-2
Hydrophobic
side chain
Hydrophilic
side chain
Leucine
Serine
Figure 3.17-s2
Carboxyl
group
Amino
group
OH
Side
chain
Side
chain
Amino acid
Amino acid
Dehydration reaction
H2O
Side
chain
Side
chain
Peptide bond
Figure 3.18
129
The amino acid sequence of lysozyme
This model allows you to see the details
of the proteins structure.
Figure 3.20
Normal
protein
Prion
Clusters
of prions
Skull
Brain
Prion
converts
normal
proteins
Bovine spongiform
encephalopathy
(BSE)
Kuru
Prion
proteins
clump
together
Denaturation
Marvel of engineering!
According to Science News reporter Richard
Lipkin, in a January 21, 1995 article - spider silk
is so strong and resilient that on the human
scale, a web resembling a fishing net could catch
a passenger plane in flight!
Video
Dr. Shibashish Chowdhury talking about the protein
folding problem