Publication List of Henry N.C.

Wong (Nai Zheng Huang)

1.
2.
3.

4.

5.

6.

7.
8.
9.
10.

11.
12.
13.

Hemiacetal formation in sulfuric acid hydrolysis of a chloro olefin.

Woo, E.P.; Mak, K.T.; Wong, H.N.C. Tetrahedron Lett. 1973, 585-588.
Synthesis of sym-dibenzo-1,5-cyclooctadiene-3,7-diyne and sym-dibenzo-1,3,5cyclooctatrien-7-yne, presumably planar conjugated eight-membered ring compounds.
Wong, H.N.C.; Garratt, P.J.; Sondheimer, F. J. Am. Chem. Soc. 1974, 96, 5604-5605.
The radical ions of benzo[b]biphenylene, a test for HMO models of biphenylene and
its derivatives.
Gerson, F.; Martin, W.B., Jr.; Sondheimer, F.; Wong, H.N.C. Helv. Chim. Acta 1975,
58, 2431-2437.
5,6,9,10-Tetradehydrobenzocycloocten, die einfachste bekannte ungeladene
Verbindung mit planarem, kinjugiertem, achtgliedrigem Carbocyclus.
Wong, H.N.C.; Sondheimer, F. Angew. Chem. 1976, 88, 126-127; Angew. Chem. Int.
Ed. Engl. 1976, 15, 117-118.
The synthesis of 2,3,6,7-dibenzobicyclo[6.2.0]deca-2,6,8-trien-4-yne-9,10-dione and
2,3,6,7-dibenzobicyclo[6.2.0]deca-2,4,6,8-tetraene-9,10-dione. The electrochemistry of
cyclobutenediones.
Wong, H.N.C.; Sondheimer, F. Goodin, R.; Breslow, R. Tetrahedron Lett. 1976, 27152718.
Electrochemical reduction of sym-dibenzocyclooctatetraene, sym-dibenzo-1,5cyclooctadiene-3,7-diyne and sym-dibenzo-1,3,5-cyclooctatrien-7-yne.
Kojima, H.; Bard, A.J.; Wong, H.N.C.; Sondheimer, F. J. Am. Chem. Soc. 1976, 98,
5560-5565.
ESR. Spectra and structures of radical anions in the dibenzi[a,e]cyclooctene series.
Gerson, F. Martin, W.B. ,Jr.; Plattner, G.; Sondheimer, F.; Wong, H.N.C. Helv. Chim.
Acta 1976, 59, 2038-2048.
Cyclic conjugated cumulene. 6,7-Didehydrobenzocyclooctene.
Wong, H.N.C.; Chan, T.-L.; Sondheimer, F. Tetrahedron Lett. 1978, 667-670.
5,12-Dihydro-6,11-didehydronaphthacene, a derivative of 1,4-didehydronaphthalene.
Wong, H.N.C.; Sondheimer, F. Tetrahedron Lett. 1980, 21, 217-220.
5,6-Didehydro-7-bromodibenzo[a,c]cyclooctene and 5,6-didehydro-8-tertbutoxydibenzo[a,c]cyclooctene as reactive intermediate. A convenient synthesis of
dibenzo[a,c]cyclooctene.
Wong, H.N.C.; Sondheimer, F. J. Org. Chem. 1980, 45, 2438-2440.
5,6-Didehydro-10-methylbenzocyclooctene.
Wong, H.N.C.; Sondheimer, F. Tetrahedron Lett. 1980, 21, 983-986.
Structure of 5,6-didehydrodibenzo[a,e]cyclooctene.
Gorter, S.; de Graaff, R.A.G.; Romers, C.; Sondheimer, F.; Wong, H.N.C. J. Chem.
Soc., Perkin Trans. II 1981, 478-480.
Synthesis and reactions of 5,6,11,12-tetradehydrodibenzo[a,e]cyclooctene and
5,6-didehydrodibenzo[a,e]cyclooctene.
Wong, H.N.C.; Sondheimer, F. Tetrahedron 1981, 37(S1), 99-109.

14.
15.
16.
17.

18.

19.

20.
21.

22.

Tribenzo[a,c,e]cyclooctene.
Huang, N.Z. Chem. Ind. (London) 1981, 364-365.
MINDO/3 Study of 1,2-didehydrocyclooctatetraenes and related planar conjugated
eight-membered carbocycles.
Huang, N.Z.; Mak, T.C.W.; Li, W.K. Tetrahedron Lett. 1981, 22, 3765-3768.
Deoxygenation of triphenylarsine oxide to triphenylarsine by low valent titanium.
Xing, Y.D.; Hou, X.L.; Huang, N.Z. Tetrahedron Lett. 1981, 22, 4727-4728.
Asymmetric total synthesis of erythromycin.I. Synthesis of an erythronolide A seco
acid derivative via asymmetric induction.
Woodward, R.B.; Logusch, E.; Nambiar, K.P.; Sakan, K.; Ward, D.E.; Au-Yeung,
B.W.; Balaram, P.; Browne, L.J.; Card, P.J.; Chen, C.H.; Chnevert, R.B.; Fliri, A.;
Frobel, K.; Gais, H.-J.; Garratt, D.G.; Hayakawa, K.; Heggie, W.; Hesson, D.P.; Hoppe,
D.; Hoppe, I.; Hyatt, J.A.; Ikeda, D.; Jacobi, P.A.; Kim, K.S.; Kobuke, Y.; Kojima, K.;
Krowicki, K.; Lee, V.J.; Leutert, T.; Malchenko, S.; Martens, J.; Matthews, R.S.; Ong,
B.S.; Press, J.B.; Rajan Babu, T.V.; Rousseau, G.; Sauter, H.M.; Suzuki, M.; Tatsuta,
K.; Tolbert, L.M.; Truesdale, E.A.; Uchida, I.; Ueda, Y.; Uyehara, T.; Vasella, A.T.;
Vladuchick, W.C.; Wade, P.A.; Williams, R.M.; Wong, H.N.C. J. Am. Chem.
Soc. 1981, 103, 3210-3213.
Asymmetric total synthesis of erythromycin.II. Synthesis of an erythronolide A
lactone system.
Woodward, R.B.; Logusch, E.; Nambiar, K.P.; Sakan, K.; Ward, D.E.; Au-Yeung,
B.W.; Balaram, P.; Browne, L.J.; Card, P.J.; Chen, C.H.; Chnevert, R.B.; Fliri, A.;
Frobel, K.; Gais, H.-J.; Garratt, D.G.; Hayakawa, K.; Heggie, W.; Hesson, D.P.; Hoppe,
D.; Hoppe, I.; Hyatt, J.A.; Ikeda, D.; Jacobi, P.A.; Kim, K.S.; Kobuke, Y.; Kojima, K.;
Krowicki, K.; Lee, V.J.; Leutert, T.; Malchenko, S.; Martens, J.; Matthews, R.S.; Ong,
B.S.; Press, J.B.; Rajan Babu, T.V.; Rousseau, G.; Sauter, H.M.; Suzuki, M.; Tatsuta,
K.; Tolbert, L.M.; Truesdale, E.A.; Uchida, I.; Ueda, Y.; Uyehara, T.; Vasella, A.T.;
Vladuchick, W.C.; Wade, P.A.; Williams, R.M.; Wong, H.N.C. J. Am. Chem.
Soc. 1981, 103, 3213-3215.
Asymmetric total synthesis of erythromycin.III. Total synthesis of erythromycin.
Woodward, R.B.; Logusch, E.; Nambiar, K.P.; Sakan, K.; Ward, D.E.; Au-Yeung,
B.W.; Balaram, P.; Browne, L.J.; Card, P.J.; Chen, C.H.; Chnevert, R.B.; Fliri, A.;
Frobel, K.; Gais, H.-J.; Garratt, D.G.; Hayakawa, K.; Heggie, W.; Hesson, D.P.; Hoppe,
D.; Hoppe, I.; Hyatt, J.A.; Ikeda, D.; Jacobi, P.A.; Kim, K.S.; Kobuke, Y.; Kojima, K.;
Krowicki, K.; Lee, V.J.; Leutert, T.; Malchenko, S.; Martens, J.; Matthews, R.S.; Ong,
B.S.; Press, J.B.; Rajan Babu, T.V.; Rousseau, G.; Sauter, H.M.; Suzuki, M.; Tatsuta,
K.; Tolbert, L.M.; Truesdale, E.A.; Uchida, I.; Ueda, Y.; Uyehara, T.; Vasella, A.T.;
Vladuchick, W.C.; Wade, P.A.; Williams, R.M.; Wong, H.N.C. J. Am. Chem.
Soc. 1981, 103, 3215-3217.
Progress in organic chemistry 1979-1980.
Huang, N.Z.; Au-Yeung, B.W. Natural Science Year Book (Shanghai) 1981, 2, 49-50.
Deoxygenation of 7-oxabicyclo[2.2.1]hepta-2,5-diene systems to substituted benzenes
by TiCl4 - LiAlH4.
Xing, Y.D.; Huang, N.Z. J. Org. Chem. 1982, 47, 140-142.
The planar dehydro[8]annulenes.
Huang, N.Z.; Sondheimer, F. Acc. Chem. Res. 1982, 15, 96-102.

23.

Clathrate inclusion compounds of tetraphenylene.

Huang, N.Z.; Mak, T.C.W. J. Chem. Soc., Chem. Commun. 1982, 543-544.
24. Deoxygenation of 7-oxabicyclo[2.2.1]hept-2-ene systems to substituted 1,3cyclohexadienes with low valent titanium.
Huang, N.Z.; Xing, Y.D.; Ye, D.Y. Synthesis 1982, 1041-1044.
25 An alternative method for the preparation of 3-alkylated-2-cycloalken-1-ones.
Zhou, Y.F.; Huang, N.Z. Syn. Commun. 1982, 12, 795-800.
26. 1,4,7,10-Tetramethyl-5,6-didehydrodibenzo[a,e]cyclooctene. A presumably planar
eight-membered ring compound.
Huang, N.Z.; Jia, J.H.; Wang, L.L.; Chan, T.-L.; Mak, T.C.W. Tetrahedron Lett. 1982,
23, 4797-4800.
27. The synthesis of presumably planar conjugated eight-membered ring compounds.
Chan, T.-L.; Huang, N.Z.; Sondheimer, F. Tetrahedron 1983, 39, 427-432.
28. Crystal and molecular structures of dibenzo[a,e]cyclooctatetraene and tribenzo[a,c,e]cyclooctatetraene.
Huang, N.Z.; Mak, T.C.W. J. Mol. Struct. 1983, 101, 135-145.
29. Semi-empirical molecular orbital conformational study of benzannelated
cyclooctatetraenes and related compounds, and X-ray crystal structure of
benzocyclooctatetraene.
Li, W.K.; Chiu, S.-W.; Mak, T.C.W.; Huang, N.Z. J. Mol. Struct., THEOCHEM. 1983,
94, 285-291.
30. Extrusion of oxygen atom from the substituted 7-oxabicyclo[2.2.1]hepta-2,5-diene
system by zinc-copper reagent.
Xing, Y.D.; Gong, Q.Q.; Huang, N.Z. Acta Chim. Sinica 1983, 41, 934-937.
31. Metal -complexes of cyclooctatetraenes. 4. Synthesis and crystal structure of
benzocyclooctatetraenesilver(I) perchlorate. Arene and olefin ligands coordinated
simultaneously to a Ag(I) ion.
Mak, T.C.W.; Ho, W.C.; Huang, N.Z. J. Organomet. Chem. 1983, 251, 413-421.
32. Metal -complexes of cyclooctatetraenes. 5. Synthesis and X-ray analysis of tetrameric
dibenzo[a,e]cyclooctatetraenecopper(I) chloride, a new "step" configuration for the
Cu4Cl4 ring.
Mak, T.C.W.; Wong, H.N.C.; Sze, K.H.; Book, L. J. Organomet.Chem. 1983, 255,
123-134.
33. The radical anions of some benzo-derivatives of dehydrocyclooctatetraenes.
Gerson, F.; Heckendorn, R.; Wong, H.N.C. Helv. Chim. Acta 1983, 66, 1409-1415.
34. Arene synthesis by extrusion of heteroatoms from 7-heteroatom-bicyclo[2.2.1]heptene
systems.
Wong, H.N.C.; Ng, T.-K.; Wong, T.-Y. Heterocycles 1983, 20, 1815-1840.
35. Tetraphenylene molecular inclusion complexes. Crystal structures of
2(tetraphenylene).X, with X = benzene, cyclohexane.
Herbstein, F.H.; Mak, T.C.W.; Reisner, G.M.; Wong, H.N.C. J. Inclusion Phenomena
1984, 1, 301-308.
36. Arene synthesis by dehydration of 7-oxabicyclo[2.2.1]heptene systems.
Wong, H.N.C.; Ng, T.-K.; Wong, T.-Y.; Xing, Y.D. Heterocycles 1984, 22, 875-890.
37. Synthesis of benzene derivatives via deoxygenation by low valent titanium.

Wong, H.N.C.; Xing, Y.D.; Zhou, Y.F.; Gong, Q.Q.; Zhang, C. Synthesis 1984, 787790.
38. MINDO/3 study of some cyclooctatetraenes containing annelated three-membered
rings.
Wong, H.N.C.; Li, W.K. J. Chem. Res. (S) 1984, 302-303.
39. A simple notation system for transition metal clusters.
Luh, T.-Y.; Wong, H.N.C.; Johnson, B.F.G. Angew. Chem. 1985, 97, 66-68; Angew.
Chem. Int. Ed. Engl. 1985, 24, 45-46.
40. Crystal structure of the clathrate inclusion compound tetraphenylene-carbon
tetrachloride (2/1).
Wong, H.N.C.; Luh, T.-Y.; Mak, T.C.W. Acta Crystallogr., Sect. C 1984, 40, 17211723.
41. The crystal structure of 4,6,8-trimethylazulene.
Wong, H.N.C.; So, K.P.; Mak, T.C.W. Z. Kristallogr. 1984, 169, 117-125.
42. The application of cyclobutane derivatives in organic synthesis.
Wong, H.N.C.; Lau, K.-L.; Tam, K.-F. Topics in Current Chemistry 1986, 133, 83-157.
43. A stable derivative of cyclooctatrienyne. Synthesis and crystal structures of 1,4,7,10tetramethyl-5,6-didehydrodibenzo[a,e]cyclooctene and 1,4,7,10-tetramethyldibenzo[a,e]cyclooctene.
Chan, T.-L.; Mak, T.C.W.; Poon, C.-D.; Wong, H.N.C.; Jia, J.H.; Wang, L.L.
Tetrahedron 1986, 42, 655-661.
44. 1-Substituted and 1,4-disubstituted tribenzo[a,c,e]cyclooctenes.
Wong, H.N.C.; Hou, X.L. Synthesis 1985, 1111-1115.
45. Asymmetric Diels-Alder reaction.
Wong, H.N.C.; Cheung, S.S.; Hou, X.-L. Organic Chemistry (Shanghai) 1986, 341351.
46. Asymmetric cyclopropanation.
Wong, H.N.C.; Chan, C.W.; Hou, X.-L. Organic Chemistry (Shanghai) 1987, 409-417.
47. Synthesis of 1,2:7,8-dibenzo[2.2]paracyclophane and 1,2-benzo-7,8-naphtho[2.2]paracyclophane.
Chan, C.W.; Wong, H.N.C. J. Am. Chem. Soc. 1985, 107, 4790.
48. Structure of 1,2:7,8-dibenzo[2.2]paracyclophane, C24H16.
Wong, H.N.C.; Chan, C.W.; Mak, T.C.W. Acta Crystallogr., Sect. C 1986, 42, 703-706.
49. Crystal structures of 1,2-benzo[2.2]paracyclophane and 1,2-benzo[2.2]paracyclophane1,7-diene.
Wong, H.N.C.; Chan, C.W.; Mak, T.C.W. Jiegou Huaxue (J. Struct. Chem.) l985, 4,
214-217.
50. Spatial notation for metal clusters.
Luh, T.-Y.; Wong, H.N.C.; Johnson, B.F.G. Polyhedron 1986, 5, 1111-1118.
51. Inclusion properties of tetraphenylene and synthesis of its derivatives.
Mak, T.C.W.; Wong, H.N.C. Topics in Current Chemistry 1987, 140, 141-164.
52. Non-benzenoid quinones.
Wong, H.N.C.; Chan, T.-L.; Luh, T.-Y. In "The Chemistry of Quinonoid Compounds",
Vol. II; Patai, S.; Rappoport, Z., Eds.; Wiley: New York, 1988; Ch.26, pp.1501-1563.
53. Stereospecific deoxygenation of epoxides to olefins.
Wong, H.N.C.; Fok, C.C.M.; Wong, T. Heterocycles 1987, 26, 1345-1382.

54.

55.

56.
57.

58.
59.

60.

61.
62.

63.
64.
65.
66.
67.

Presumably coplanar derivatives of tribenzo[a,c,e]cyclooctene: Synthesis of 10,11methano-lH-benzo[5,6]cycloocta[1,2,3,4-def]fluorene-1,14-dione and 1,1,14,14tetramethyl-10,11-methano-1H-benzo[5,6]cycloocta[1,2,3,4-def]fluorene.

Hou, X.L.; Wong, H.N.C. J. Am. Chem. Soc. 1987, 109, 1868-1869.
The radical anion of 1,2:9,10-dibenzo[2.2]paracyclophane. An ESR, ENDOR and
TRIPLE resonance study.
Gerson, F.; Martin, W.B., Jr.; Wong, H.N.C.; Chan, C.W. Helv. Chim.Acta 1987, 70,
79-90.
Reduction of enedicarboxylate compounds with low valent titanium.
Hung, C.W.; Wong, H.N.C. Tetrahedron Lett. 1987, 28, 2393-2396.
Data Bank: The PE spectra of paracyclophanes with unsaturated bridges and of related
molecules.
Yang, Z.-Z.; Kovac, B.; Heilbronner, E.; Lecoultre, J.; Chan, C.W.; Wong, H.N.C.;
Hopf, H.; Vgtle, F. Helv. Chim. Acta 1987, 70, 299-307.
Synthesis of tetrabenzo[b,h,n,t]tetraphenylene and crystal structure of its 1:1 clathrate
inclusion compound with p-xylene.
Wong, H.N.C.; Man, Y.-M.; Mak, T.C.W. Tetrahedron Lett. 1987, 28 , 6359-6362.
Zinc-silver couple: A mild and convenient reagent for reductive dehalogenation of aryl
halides.
Chung, C.K.; Ho, M.S.; Lun, K.S.; Wong, M.O.; Wong, H.N.C.; Tam, S.W. Syn.
Commun. 1988, 18, 507-510.
Synthesis of cycloocta[2,1-b:3,4-b']diquinoline and cycloocta[2,1-b:3,4-b]di[1,8]naphthyridine, and X-ray crystal structures of cycloocta[2,1-b:3,4-b]diquinoline and
its 2:1 complex with copper perchlorate.
Wang, X.C.; Wong, H.N.C.; Mak, T.C.W. Tetrahedron Lett. 1987, 28, 5833-5836.
The chemistry of dibenzo[2.2]paracyclophane and its related compounds. Evidence for
the existence of a cyclophyne intermediate.
Chan, C.W.; Wong, H.N.C. J. Am. Chem. Soc. l988, 110, 462-469.
Arene synthesis by extrusion reaction X. Synthesis of arenes by deoxygenation of
endoxide with cyclopentadienyl titanium trichloride - lithium aluminum hydride and
dicyclopentadienyl titanium dichloride - lithium aluminum hydride.
Wong, C.H.; Hung, C.W.; Wong, H.N.C. J. Organomet. Chem. 1988, 342, 9-14.
Use of cyclopropanes and their derivatives in organic synthesis.
Wong, H.N.C.; Hon, M.-Y.; Tse, C.-W.; Yip, Y.-C.; Tanko, J.; Hudlicky, T.
Chem. Rev. 1989, 89, 165-198.
Synthesis and conformational behavior of dibenzo[2.2]metaparacyclophanediene.
Wong, T.; Cheung, S.S.; Wong, H.N.C. Angew. Chem. 1988, 100, 716-717.
Angew. Chem. Int. Ed. Engl. 1988, 27, 705-706.
Benzo-fused tetraphenylenes: Synthesis and X-ray crystallographic study of a 4:1
clathrate inclusion compound of dibenzo[b,h]tetraphenylene with p-xylene.
Man, Y.-M.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem. 1990, 55, 3214-3221.
Planar cyclooctatetraenes: examples of molecular structure manipulation.
Wong, H.N.C.; Chan, K.H.; Cheung, S.S.; Hou, X.L. Organic Chemistry (Shanghai),
1991, 11, 13-25.
Synthesis of novel benzenoid molecules by low-valent titanium deoxygenation.
Wong, H.N.C. Acc. Chem. Res. 1989, 22, 145-152.

68.

69.
70.
71.
72.

73.
74.

75.

76.
77.
78.

79.

80.

Enantiomer resolution, absolute configuration, and attempted thermal racemization of

two tetrabenzocyclooctatetraene (o-tetraphenylene) derivatives. An exceptionally high
barrier to ring inversion.
Rashidi-Ranjbar, P.; Man, Y.-M.; Sandstrm, J.; Wong, H.N.C. J. Org. Chem. 1989,
54, 4888-4892.
The chemistry of cycloocta[2,1-b:3,4-b]dipyridine and its derivatives.
Wang, X.C.; Wong, H.N.C. Pure Appl. Chem. 1990, 62, 565-568.
Recent progress in the synthesis of five-membered carbocycles.
Wang, X.C.; Wong, H.N.C. in Progress in Organic Synthesis; Dai, L.-X.; Qian, Y.-L.,
Eds.; Chemical Industry Publishers: Shanghai, 1993; pp 137-181.
A ligustilide dimer from Angelica Sinensis.
Hon, P.M.; Lee, C.M.; Choang, T.F.; Chui, K.Y.; Wong, H.N.C. Phytochemistry 1990,
29, 1189-1191.
Novel constituents of the Chinese drug Danshen (Salvia miltiorrhiza Bunge):
Isolation of 6,7,8,9-tetrahydro-1,6,6-trimethylfuro[3,2-c]naphth[2,1-e]oxepin-10,12dione and its derivatives, secondary metabolites produced by photo-oxidation reactions.
Chang, H.M.; Choang, T.F.; Chui, K.Y.; Hon, P.M.; Lee, C.M.; Mak, T.C.W.; Wong,
H.N.C. J. Chem. Res. (S) 1990, 114-115; J. Chem. Res. (M) 1990, 0877-0886.
Synthesis and reactions of 3,4-bis(trimethylsilyl)furan and 2-methyl-3,4-bis(trimethylsilyl)furan.
Ho, M.S.; Wong, H.N.C. J. Chem. Soc., Chem. Commun. 1989, 1238-1240.
Structure elucidation and total synthesis of new tanshinones isolated from Salvia
miltiorrhiza Bunge (Danshen).
Chang, H.M.; Cheng, K.P.; Choang, T.F.; Chow, H.F.; Chui, K.Y.; Hon, P.M.; Tan, F.
W.L.; Yang, Y.; Zhong, Z.P.; Lee, C.M.; Sham, H.L.; Chan, C.F.; Cui, Y.X.; Wong, H.
N.C. J. Org. Chem. 1990, 55, 3537-3543.
Synthesis, metal complex formation and resolution of a new C2 diazabiaryl ligand:
cycloocta[2,1-b:3,4-b]dipyridine.
Wang, X.C.; Cui, Y.X.; Mak, T.C.W.; Wong, H.N.C. J. Chem. Soc., Chem. Commun.
1990, 167-169.
Synthesis of benzo[a]phenanthro[9,10-e]cyclooctene.
Cheng, S.K.T.; Wong, H.N.C. Syn. Commun. 1990, 20, 3053-3061.
Structural studies of some derivatives of cyclohexane-1,3,5-tricarboxylic acid.
Chan, T.-L.; Cui, Y.X.; Mak, T.C.W.; Wang, R.J.; Wong, H.N.C. J. Cryst. Spectrosc.
Res. 1991, 21, 297-308.
A planar and stable derivative of 13,14-didehydrotribenzo[a,c,e]cyclooctene:
synthesis and X-ray crystal structure of 5,6-didehydro-1,1,14,14-tetramethyl-10,11methano-1H-benzo[5,6]cycloocta[1,2,3,4-def]fluorene.
Wang, X.M.; Wang, R.J.; Mak, T.C.W.; Wong, H.N.C. J. Am. Chem. Soc. 1990, 112,
7790-7791.
Structure modification of miltirone, an active central benzodiazepine receptors ligand
isolated from Salvia miltiorrhiza Bunge (Danshen).
Chang, H.M.; Chui, K.Y.; Tan, F.W.L.; Yang, Y.; Zhong, Z.P.; Lee, C.M.; Sham, H.L.;
Wong, H.N.C. J. Med. Chem. 1991, 34, 1675-1692.
Prehispanolone, a new labdane diterpene from Leonurus heterophyllus.
Hon, P.M.; Lee, C.M.; Shang, H.S.; Cui, Y.X.; Wong, H.N.C.; Chang, H.M.

81.

82.

83.

84.

85.
86.

87.
88.
89.
90.

91.

92.

Phytochemistry 1991, 30, 354-356.

Synthesis of diazepam related analogues of miltirone, an active central
benzodiazepine receptors ligand isolated from Salvia miltiorrhiza Bunge (Danshen).
He, Y.; Lau, Y.K.; Chang, H.M.; Lee, C.M.; Wang, R.J.; Mak, T.C.W.; Cui, Y.X.;
Wong, H.N.C. J. Chem. Soc., Perkin Trans. 1 1990, 3359-3361.
Naturally occurring benzofuran: isolation, structure elucidation and total synthesis of
5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzo[b]furancarboxaldehyde, a novel adenosine A1 receptor ligand isolated from Salvia miltiorrhiza
Bunge (Danshen).
Yang, Z.; Hon, P.M.; Chui, K.Y.; Xu, Z.L.; Chang, H.M.; Lee, C.M.; Cui, Y.X.; Wong,
H.N.C.; Poon, C.D.; Fung, B.M. Tetrahedron Lett. 1991, 32, 2061-2064.
Miltirone, a central benzodiazepine receptor parital agonist from a Chinese
medicinal herb Salvia mildtiorrhiza.
Lee, C.M.; Wong, H.N.C.; Chui, K.Y.; Hon, P.M.; Choang, T.F.; Chang, H.M.
Neuroscience Lett. 1991, 127, 237-241.
Prehispanolone, a novel platelet activating factor receptor antagonist from Leonurus
heterophyllus.
Lee, C.M.; Jiang, L.M.; Shang, H.S.; Hon, P.M.; He, Y.; Wong, H.N.C.; Chang, H.M.
British J. Pharmacology 1991, 108, 1719-1724.
Effects of non-planarity in the radical anions of tribenzo[a,c,e]cyclooctenes.
Felder, P.; Gerson, F.; Gescheidt, G.; Heckendorn, R.; Tong, T.H.; Wang, X.M.; Wong,
H.N.C.; Hou, X.L. Helv. Chim. Acta 1991, 74, 644-653.
The cyclopropanes.
Wong, H.N.C. In Rodds Chemistry of Carbon Compounds; Sainsbury, M., Ed.;
Elsevier: Amsterdam, 1992, 2nd Supplement to 2nd Edition, Part II A and B,
Chapter 2, pp 81-124.
Synthesis of eupolauridine and its benzo-annulated derivative.
Tong, T.H.; Wong, H.N.C. Syn. Commun. 1992, 22, 1773-1782.
Anodic oxidation as a synthetic expedient to naphthoquinone and anthraquinone ketals.
Yang, Z.; Cui, Y.X.; Wong, H.N.C.; Wang, R.J.; Mak, T.C.W.; Chang, H.M.; Lee,
C.M.; Poon, C.D.; Fung, B.M. Tetrahedron 1992, 48, 3293-3302.
A modified synthesis of ()--aryllactic acids.
Wong, H.N.C.; Xu, Z.L.; Chang, H.M.; Lee, C.M. Synthesis 1992, 793-797.
Synthesis of cyclobutanes from cyclobutenes.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds; Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7 A.1.1.1, pp 29-40.
Synthesis of cyclobutanes from bicyclo[1.1.0]butanes.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7 A.1.1.2, pp 41-58.
Synthesis of cyclobutanes from a C4 building block by 1,4-elimination of halogens
from 1,4-dihalides and similar difunctional compounds.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Three-

and Four-Membered Ring Compounds, Additional and Supplementary Volumes to the

4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.A.1.1.3, pp 59-62.
93. Synthesis of cyclobutanes from a C4 building block by 1,4-elimination of HX from
-halo carbonyl derivatives and similar difunctional compounds.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.A.1.1.4, pp 63-70.
94. Synthesis of cyclobutanes from a C3 and a C1 building-block by ring-enlargement of
cyclopropane derivatives.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.A.1.2.1, pp 76-77.
95. Synthesis of cyclobutanes from a C3 and a C1 building-block by geminal dialkylation
of C-H acidic compounds.
Wong,
H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.A.1.2.2, pp 78-84.
96. Elimination reactions of cyclobutanes.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.1, pp 435-446.
97. Hydrogenolysis and addition reactions of cyclobutanes.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.1 and 7.B.2.2, pp 447-457.
98. Cycloreversion reactions of cyclobutanes.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the 4
th Edition; de Meijere,A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.3, pp 457-469.
99. Rearrangement reactions of cyclobutanes with ring-opening: alkenes by H-shifts and
cyclobutylmethyl to pent-1-enyl rearrangement.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.4.1.1, pp 470-483.
100. Rearrangement reactions with ring-opening: cyclobutylidene-methylenecyclopropane
rearrangement.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-Membered Ring Compounds, Additional and Supplementary Volumes to the

101.

102.

103.

104.
105.

106.

107.

108.

109.
110.
111.

4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.4.1.3, pp 487-494.
Formation of five-membered rings by cyclobutylmethyl to cyclopentyl rearrangement.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.4.2.1, pp 495-521.
Formation of five-membered rings by cyclobutylcarbene to cyclopentene
rearrangement.
Wong, H.N.C. In Houben-Weyl Methods of Organic Chemistry: Carbocyclic Threeand Four-membered Ring Compounds, Additional and Supplementary Volumes to the
4th Edition; de Meijere, A., Ed.; Georg Thieme Verlag: Stuttgart, 1997; Vol. E17e,
Section 7.B.2.4.2.2, pp 522-524.
A novel synthesis of the dibenz[b,f]oxepin ring system: 10,11-dihydro-11-hydroxydibenz[b,f]oxepin-10(11H)-one.
Yang, Z.; Wong, H.N.C.; Hon, P.M.; Chang, H.M.; Lee, C.M. J. Org. Chem. 1992,
57, 4033-4034.
3,4-Bis(tri-n-butylstannyl)furan: a versatile building block for the regiospecific
synthesis of 3,4-disubstituted furans.
Yang, Y.; Wong, H.N.C. J. Chem. Soc., Chem. Commun. 1992, 656-658.
Enantiomer resolution, barrier to ring inversion, circular dichroism spectrum, and
absolute configuration of cycloocta[2,1-b:3,4-b]dipyridine.
Rashidi-Ranjbar, P.; Sandstrm, J.; Wong, H.N.C.; Wang, X.C. J. Chem. Soc.,
Perkin Trans. 2 1992, 1625-1628.
Regioselective introduction of carbon-3 substituents to 5-alkyl-7-methoxy-2phenylbenzo[b]furans: synthesis of a novel adenosine A1 receptor ligand and its
derivatives.
Yang, Z.; Liu, H.B.; Lee, C.M.; Chang, H.M.; Wong, H.N.C. J. Org. Chem. 1992, 57,
7248-7257.
Regiospecific conversion of 3,4-bis(trimethylsilyl)furan to 3,4-disubstituted furans: a
palladium-catalyzed Suzuki-type coupling of boroxines.
Song, Z.Z.; Zhou, Z.Y.; Mak, T.C.W.; Wong, H.N.C. Angew. Chem. 1993, 105, 406408. Angew. Chem. Int. Ed. Engl. 1993, 32, 432-434.
Regiospecific introduction of carbon-3 formyl group to 5,7-dialkyl-7-methoxybenzo[b]furans: synthesis of potential ligands for adenosine A1 receptors.
Wong, H.N.C.; Niu, C.R.; Yang, Z.; Chang, H.M.; Lee, C.M. Tetrahedron 1992, 48,
10339-10344.
Enantioselective synthesis of chiral liquid crystalline compounds from monoterpenes.
Wang, Q.; Fan, S.Y.; Wong, H.N.C.; Li, Z.; Fung, B.M.; Twieg, R.J.; Nguyen, H.T.
Tetrahedron 1993, 49, 619-638.
Lithiation of 3,4-bis(tri-n-butylstannyl)furan: regiospecific synthesis of unsymmetrical
3,4-disubstituted furans.
Yang, Y.; Wong, H.N.C. J. Chem. Soc., Chem. Commun. 1992, 1723-1725.
Preleoheterin and leoheterin, two new labdane diterpenes from Leonurus heterophyllus.
Hon, P.M.; Wang, E.S.; Lam, S.K.M.; Choy, Y.M.; Lee, C.M.; Wong, H.N.C.
Phytochemistry 1993, 33, 639-641.

112. MNDO study of some [6]paracyclophanes with unsaturated chains.

Wong, C.-K.; Cheung, Y.-S.; Wong, H.N.C.; Li, W.-K. J. Chem. Res. (S) 1993, 308309. J. Chem. Res. (M) 1993, 2001-2039.
113. Synthesis and conformational behavior of benzo[2.2]metaparacyclophan-9-ene,
dibenzo[2.2]metaparacyclophane and 1,4-dimethyl-dibenzo[2.2]metaparacyclophane.
X-Ray crystal structure of dibenzo[2.2]metaparacyclophane.
Wong, T.; Yuen, M.S.M.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem. 1993, 58, 31183122.
114. Demonstration of the myocardial salvage effect of lithospermic acid B isolated from
the aqueous extract of Salvia miltiorrhiza
Fung, K.P.; Zeng, L.H.; Wu, J.; Wong, H.N.C.; Lee, C.M.; Hon, P.M.; Chang, H.M.;
Wu, T.W. Life Sciences 1993, 52, PL 239-244.
115. Regiospecific mono-ipso-iodination of 3,4-bis(trimethylsily)furan and regiospecific
ipso-iodination of tris[(4-substituted)furan-3-yl]boroxines: Synthesis of 3-trimethylsilyl
-4-substituted furans and unsymmetrical 3,4-disubstituted furans.
Song, Z.Z.; Wong, H.N.C. Liebigs Ann. Chem. 1994, 29-34.
116. Coplanar and stable derivatives of 13,14-didehydro-tribenzo[a,c,e]cyclooctene:
Synthesis of 5,6-didehydro-1,1,14,14-tetramethyl-10,11-methano-1H-benzo[5,6]cycloocta[1,2,3,4-def]fluorene and 5,6-didehydro-10,11-methano-1H-benzo[5,6]cycloocta[1,2,3,4-def] fluorene-1,14-dione and X-ray crystal structures of 1,1,14,14tetramethyl-10,11-methano-1H-benzo[5,6]cycloocta[1,2,3,4-def]fluorene and 1,12dihydro-1,1,12,12-tetramethyl-dicyclopenta[def,jkl]tetraphenylene.
Wang, X.-M.; Hou, X.-L.; Zhou, Z.-Y.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem.
1993, 58, 7498-7506.
117. Lithospermic acid B as an antioxidant-based protector of cultured ventricular myocytes
and aortic endothelial cells of rabbits.
Fung, K.P.; Wu, J.; Zeng, L.H.; Wong, H.N.C.; Lee, C.M.; Hon, P.M.; Chang, H.M.;
Wu, T.W. Life Sciences 1993, 53, PL 189-193.
118. Regiospecific synthesis of furan-3,4-diyl oligomers via palladium-catalyzed selfcoupling of organoboroxines.
Song, Z.Z.; Wong, H.N.C. J. Org. Chem. 1994, 59, 33-41.
119. University Chemical Research and Education in Hong Kong (in Japanese).
Che, C.M.; Hiraoka, H.; Mak, T.C.W.; Wong, H.N.C. Chemistry and Chemical
Technology 1993, 46, 1059-1062.
120. Synthesis and reactions of 3,4-bis(trimethylsilyl)furan: Diels-Alder cycloaddition,
Friedel-Crafts acylation and regiospecific conversion to 3,4-disubstituted furans.
Song, Z.Z.; Ho, M.S.; Wong, H.N.C. J. Org. Chem. 1994, 59, 3917-3926.
121. Planar dehydro[8]annulenes and other theoretically interesting molecules.
Wong, H.N.C. In Advances in Theoretically Interesting Molecules; Thummel, R.P., Ed.;
JAI Press: Greenwich, Connecticut, 1995; Vol. 3, pp 109-146.
122. Dibenzo[a,e]cyclooctene: a nonplanar radical cation.
Gerson, F.; Felder, P.; Schmidlin, R.; Wong, H.N.C. J. Chem. Soc., Chem. Commun.
1994, 1659-1660.
123. Model study and partial synthesis of prehispanolone and 14,15-dihydroprehispanolone
from hispanolone.
Wang, E.S.; Luo, B.S.; Mak, T.C.W.; Choy, Y.M.; Wong, H.N.C. Tetrahedron Lett.

124.
125.

126.

127.
128.

129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
140.

1994, 35, 7401-7404.

Regiospecific synthesis of 3,4-disubstituted furans and 3-substituted furans using 3,4bis(tri-n-butylstannyl)furan and 3-(tri-n-butylstannyl)furan as building blocks.
Yang, Y.; Wong, H.N.C. Tetrahedron 1994, 50, 9583-9608.
Tetraphenylene and related hosts.
Mak, T.C.W.; Wong, H.N.C. In Comprehensive Supramolecular Chemistry; MacNicol,
D.D.; Toda, F.; Bishop, R., Eds.; Pergamon Press: Oxford, 1996; Vol. 6, Chapter 11, pp
351-369.
Regiospecific displacement of the C-B bond of tris[4-(substituted)furan-3-yl]boroxines
with C-Sn bond and C-O bond: syntheses of 3,4-disubstituted furans and 4-substituted3(2H)-furanones.
Song, Z.Z.; Wong, H.N.C. J. Chin. Chem. Soc. 1995, 42, 673-679.
Regiospecific synthesis of 3,4-disubstituted furans.
Song, Z.Z.; Wong, H.N.C.; Yang, Y. Pure Appl. Chem. 1996, 68, 723-726.
The chemistry of novel C2 diazabiaryl ligands: cycloocta[2,1-b:3,4-b]dipyridine,
cycloocta[2,1-b:3,4-b]diquinoline and their related compounds.
Wang, X.C.; Wong, H.N.C. Tetrahedron 1995, 51, 6941-6960.
Chiral liquid crystalline compounds from D-(+)-glucose .
Ho, W.M.; Wong, H.N.C.; Navailles, L.; Destrade, C.; Ngugen, H.T.; Isaert, N.
Tetrahedron 1995, 51, 7373-7388.
Regiospecific synthesis of polysubstituted furans and their application in organic
synthesis.
Wong, H.N.C. Pure Appl. Chem. 1996, 68, 335-344.
Regiospecific synthesis of 3,4-disubstituted thiophenes.
Ye, X.S.; Wong, H.N.C. J. Chem. Soc., Chem. Commun. 1996, 339-340.
Synthesis and structure characterization of 5,6,15,16-tetradehydrobenzo[a]phenanthro[9,10-e]cyclooctene, C24H12.
Leung, C.Y.; Mak, T.C.W.; Wong, H.N.C. J. Chem. Crystallogr. 1996, 26, 227-230.
Ester exchange reaction of azlactones catalyzed by sodium acetate
Xu, Z.L.; Wong, H.N.C. Organic Chemistry (Shanghai) 1995, 15, 292-295.
3,4-Didehydrothiophene: generation, trapping reactions and ab initio study.
Ye, X.S.; Li, W.-K.; Wong, H.N.C. J. Am. Chem. Soc. 1996, 118, 2511-2512.
An ab initio study of some five-membered heteroarynes.
Wong, H.N.C.; Ye, X.-S.; Cheung, Y.-S.; Li, W.-K. J. Chem. Res. (S) 1996, 458-459.
Synthetic studies of prehispanolone and 14,15-dihydroprehispanolone.
Wang, E.S.; Choy, Y.M.; Wong, H.N.C. Tetrahedron 1996, 52, 12137-12158.
Relaxant actions of non-prostanoid prostacyclin mimetics on human pulmonary artery.
Jones, R.L.; Qian, Y.-M.; Wise, H.; Wong, H.N.C.; Lam, W.-L.; Chan, H.W.; Yim,
A.P.C.; Ho, J.K.S. J. Cardiovasc. Pharmacol. 1997, 29, 525-535.
Regiospecific synthesis of polysubstituted furans from silylated furans: expedient
syntheses of rosefuran.
Wong, M.K.; Leung, C.Y.; Wong, H.N.C. Tetrahedron 1997, 53, 3497-3512.
Regiospecific synthesis of 3,4-disubstituted furans and thiophenes.
Ye, X.-S.; Yu, P.; Wong, H.N.C. Liebigs Annalen 1997, 459-466.
Relaxant actions of prostanoid and non-prostanoid IP-receptor agonists on the human
pulmonary artery.

Jones, R.L.; Qian, Y.M.; Wise, H.; Wong, H.N.C.; Chan, H.W.; Lam, W.W.L.; Ho, J.K.
S.; Yim, A.P.C. Brit. J. Pharmacol. (Proc. Suppl.) 1996, 119, 193P.
141. Synthetic applications of 3,4-bis(trimethylsilyl)thiophene: unsymmetrically 3,4disubstituted thiophenes and 3,4-didehydrothiophene.
Ye, X.-S.; Wong, H.N.C. J. Org.Chem. 1997, 62, 1940-1954.
142. Reaction of 2-methylnaphthalene with hexachlorocyclopentadiene and structural
characterization of a new addition-substitution product.
Du, D.-M.; Xue, F.; Wong, H.N.C.; Mak, T.C.W. J. Chem. Crystallogr. 1998, 28, 787790.
143.Determination of the very high barriers to conformational processes by the neat
racemization technique. Part 1: Barriers to ring inversion in dibenzo[a,c]dinaphtho[2,3e; 2,3-g]cyclooctatetraene and hindered rotation in 2,2'-dimethyl binaphthyl.
Rashidi-Ranjbar, P.; Sandstrm, J.; Schriver, G.W.; Wong, H.N.C. Iran. J. Chem. and
Chem. Eng. 1996, 15, 18-22.
144. Total syntheses of sphydrofuran, secosyrins and syributins.
Yu, P.; Yang, Y.; Zhang, Z.Y.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem. 1997, 62,
6359-6366.
145. The enol form structure and Clemmensen reduction mechanism of 3-arylpyruvic acid.
Xu, Z.-L.; Wong, H.N.C. Youji Huaxue (Shanghai) 1996, 16, 440-444.
146. 3,4-Bis(trimethylsilyl)-1H-pyrrole: a versatile building block for unsymmetrically 3,4disubstituted pyrroles.
Chan, H.-W.; Chan, P.-C.; Liu, J.-H.; Wong, H.N.C. J. Chem. Soc., Chem. Commun.
1997, 1515-1516.
147. Regioselective syntheses of substituted furans.
Hou, X.L.; Cheung, H.Y.; Hon, T.Y.; Kwan, P.L.; Lo, T.H.; Tong, S.Y.; Wong, H.N.C.
Tetrahedron 1998, 54, 1955-2020.
148. Synthetic studies on 2-substituted-1,7-dioxaspiro[4.4]nonan-1-one.
Wang, E.S.; Shen, J.-C.; Wong, H.N.C. Chem. J. Chin. Universities 1997, 18, 10541056.
149. An improved synthesis of (-)-syringolides and X-ray structural characterization of
synthetic (-)-syringolide 1.
Yu, P.; Wang, Q.-G.; Mak, T.C.W.; Wong, H.N.C. Tetrahedron 1998, 54, 1783-1788.
150. Prostanoid action on the human pulmonary vascular system.
Jones, R.L.; Qian, Y.-M.; Wong, H.N.C.; Chan, H.-W.; Yim, A.P.C. Clin. Exp.
Pharmacol. Physiol. 1997, 24, 969-972.
151. The cleavage of trimethylsilyl ether.
Wang, E.S.; Shen, J.-C.; Wong, H.N.C. Chem. J. Chin. Universities 1997, 18, 16481650.
152. On the absolute structure of optically active neolignans containing a dihydrobenzo[b]furan skeleton.
Yuen, M.S.M.; Xue, F.; Mak, T.C.W.; Wong, H.N.C. Tetrahedron 1998, 54, 1242912444.
153. A total synthesis of ()-hispanolone.
Cheung, W.S.; Wong, H.N.C. Tetrahedron Lett. 1998, 39, 6521-6524.
154. The generation and trapping reactions of 1-tert-butoxycarbonyl-3,4-didehydro-1Hpyrrole.

155.

156.
157.
158.
159.
160.
161.
162.

163.

164.
165.
166.
167.
168.

Liu, J.-H.; Chan, H.-W.; Xue, F.; Wang, Q.-G.; Mak, T.C.W.; Wong, H.N.C. J. Org.
Chem. 1999, 64, 1630-1634.
The attempted generation of 3,4-didehydrofuran.
Wu, Y.-M.; Yang, X.-P.; Xue, F.; Mak, T.C.W.; Wong, H.N.C. J. Chin. Chem. Soc.
(Special Issue in Commemorating the 70th Anniversary of Institute of Chemistry,
Academia Sinica, Taipei) 1999, 46, 463-468.
A tale of three cities: planar dehydro[8]annulenes and their reverberations.
Wong, H.N.C. Chinese University Bulletin 1998, Supplement 40 (Professorial
Inaugural Lecture Series 25), pp 1-24.
The use of furans in natural product syntheses.
Wong, H.N.C.; Yu, P.; Yick, C.Y. Pure Appl. Chem.1999, 71, 1041-1044.
Molecular arrangement in mesogenic compounds with a terminal cyano group.
Allouchi, H.; Belaaraj, A.; Wong, H.N.C.; Nguyen, H.T.; Cotrait, M. Mol. Cryst. Liq.
Cryst. 1999, 326, 279-290.
Synthesis and optical properties of poly(thienylacetylenes).
Tang, B.-Z.; Poon, W.-H.; Peng, H.; Wong, H.N.C.; Ye, X.-S.; Monde, T. Chin. J.
Polym. Sci. 1999, 17, 81-86.
Total synthesis of naturally occurring molecules possessing 1,7-dioxaspiro[4.4]nonane
skeletons.
Wong, H.N.C. Eur. J. Org. Chem. 1999, 1757-1765.
Total Synthesis of (-)-Hispanolone And An Improved Approach Towards
Prehispanolone.
Cheung, W.S.; Wong, H.N.C. Tetrahedron 1999, 55, 11001-11016.
Synthesis, structure and inclusion properties of 2,5,8,11-tetrahydro-2,5,8,11-tetraoxodibenzo[b,h]tetraphenylene.
Yang, X.-P.; Du, D.-M.; Li, Q.; Mak, T.C.W.; Wong, H.N.C. Chem. Commun. 1999,
1607-1608.
Highly regioselective synthesis of 2,3,4-trisubstituted-1H-pyrroles: A formal total
synthesis of lukianol A.
Liu, J.-H.; Yang, Q.-C.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem. 2000, 65, 35873595.
Highly regioselective synthesis of 3,4-disubstituted-1H-pyrroles.
Liu, J.-H.; Chan, H.-W.; Wong, H.N.C. J. Org. Chem. 2000, 65, 3274-3283.
Structure-property relationships for photoconduction in substituted polyacetylenes.
Tang, B.-Z.; Chen, H.-Z.; Xu, R.-S.; Lam, J.W.Y.; Cheuk, K.K.L.; Wong, H.N.C.;
Wang, M. Chem. Mater. 2000, 12, 213-221.
5,6-Bis(trimethylsilyl)benzo[c]furan: a versatile building block for linear polycyclic
aromatic compounds.
Yick, C.-Y.; Chan, S.-H.; Wong, H.N.C. Tetrahedron Lett. 2000, 41, 5957-5961.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Wong, H.N.C. Progress in Heterocyclic Chemistry; Gribble, G.
W.; Gilchrist, T.L., Eds.; Pergamon Press: Oxford, 2001; Vol. 13, pp 130-166.
Regiospecific substitution of the carbon-boron bond of tris(4-methylfuran-3-yl)boroxine: a model ring C - BC - ABC approach towards eudesmanolides.
Yick, C.-Y.; Wong, H.N.C. Tetrahedron 2001, 57, 6935-6940.

169. On the diastereocontrol in the formation of (2R,3S)-3-(3'-furyl)1,2-O-isopropylidenedioxy-3-pentanol and its (2R,3R)-diastereomer.

Hui, C.W.; Lee, H.K.; Wong, H.N.C. Tetrahedron Lett. 2002, 43, 123-126.
170. Diastereoselective addition reactions of furyl aldehydes using chiral boronates as
auxiliary: application to the enantiselective synthesis of 2,3-disubstituted furyl alcohols.
Chan, K.-F.; Wong, H.N.C. Org. Lett. 2001, 3, 3991-3994.
171. A concise strategy for polymer-supported regio-oriented introduction of various
building blocks onto glucopyranoside scaffold.
Liao, Y.; Li, Z.-M.; Wong, H.N.C. Chin. J. Chem. 2001, 19, 1119-1129.
172. Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Wong, H.N.C. Progress in Heterocyclic Chemistry; Gribble, G.
W.; Gilchrist, T.L., Eds.; Pergamon Press: Oxford, 2002; Vol. 14, pp 139-179.
173. Synthetic studies of furanosesquiterpenoid tetrahydrolinderazulenes. Total synthesis of
()-echinofuran.
Yim, H.-K.; Liao, Y.; Wong, H.N.C. Tetrahedron 2003, 59, 1877-1884.
174. 5,6-Bis(trimethylsilyl)benzo[c]furan: an isolable versatile building block for linear
polycyclic aromatic compounds.
Chan, S.-H.; Yick, C.-Y.; Wong, H.N.C. Tetrahedron 2002, 46, 9413-9422.
175. An enantioselective synthetic pathway towards plakortones.
Lee, H.-K.; Wong, H.N.C. Chem. Commun. 2002, 2114-2115.
176. Diastereoselective aldol reactions of furanyl aldehydes using chiral boronates as
auxiliary: application to the synthesis of enantiomerically pure and highly
functionalized 2,3-disubstituted furanyl alcohols.
Chan, K.-F.; Wong, H.N.C. Eur. J. Org. Chem. 2003, 82-91.
177. Synthesis and studies of 1,4,5,8,9,12,13,16-Octamethoxytetraphenylene.
Lai, C.-W.; Lam, C.-K.; Lee, H.-K.; Mak, T.C.W.; Wong, H.N.C. Org. Lett. 2003, 5,
823-826.
178. Regiospecific substitution of the carbon-boron bond of tris(4-trimethylsilylfuran-3-yl)boroxine and tris(4-methylfuran-3-yl)boroxine: model approaches towards
sesquiterpenoid furanoeudesmanes.
Yick, C.-Y.; Tsang, T.-K.; Wong, H.N.C. Tetrahedron 2003, 59, 325-333.
179. Synthetic studies of erythromycin derivatives: 6-O-methylation of (9S)-12,21-anhydro9-dihydroerythromycin A derivatives.
Chen, W.-M.; Wong, H.N.C.; Chu, D.T.W.; Lin, X.-D. Tetrahedron 2003, 59, 70337045.
180. Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Wong, H.N.C. Progress in Heterocyclic Chemistry; Gribble, G.
W.; Joule, J., Eds.; Pergamon Press: Oxford, 2003; Vol. 15, pp 167-205.
181. Synthesis, resolution and applications of 1,16-dihydroxytetraphenylene as a novel
building block in molecular recognition and assembly.
Wen, J.-F.; Hong, W.; Yuan, K.; Mak, T.C.W.; Wong, H.N.C. J. Org. Chem. 2003, 68,
8918-8931.
182. The application of cyclobutane derivatives.
Fu, N.-Y.; Chan, S.-H.; Wong, H.N.C. In The Chemistry of Cyclobutanes; Rappoport,
Z., Ed.; Wiley-VCH: Weinheim, 2004, pp 357-440.
183. Diastereoselective addition reactions of furyl sulfonylimine using chiral boronates as

184.

185.
186.
187.
188.

189.
190.
191.

192.
193.

194

195.
196.

auxiliary: applications to the enantioselective synthesis of 2,3-disubstituted furyl

sulfonylamides.
Yim, H.-K.; Wong, H.N.C. J. Org. Chem. 2004, 69, 2892-2895.
A soluble pentacene: synthesis, EPR and electrochemical studies of 2,3,9,10-tetrakis(trimethylsilyl)pentacene.
Chan, S.-H.; Lee, H.-K.; Wang, Y.-M.; Fu, N.-Y.; Chen, X.-M.; Cai, Z.; Wong, H.N.C.
Chem. Commun. 2005, 66-68.
Synthesis of 1,4,5,16-tetrahydroxytetraphenylene.
Hui, C.W.; Mak, T.C.W.; Wong, H.N.C. Tetrahedron 2004, 60, 3523-3531.
Use of furans in synthesis of bioactive compounds.
Lee, H.-K.; Chan, K.-F.; Hui, C.-W.; Yim, H.-K.; Wu, X.-W.; Wong, H.N.C. Pure
Appl. Chem. 2005, 77, 139-143.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2004; Vol. 16, pp 156-197.
Chiral rod-like platinum complexes, double helical chains and potential asymmetric
hydrogenation ligand base on "linear" building blocks: 1,8,9,16-tetrahydroxytetraphenylene and 1,8,9,16-tetrakis(diphenylphosphino)tetraphenylene.
Peng, H.-Y.; Lam, C.-K.; Mak, T.C.W.; Cai, Z.; Ma, W.-T.; Li, Y.-X.; Wong, H.N.C. J.
Am. Chem. Soc. 2005, 127, 9603-9611.
Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells.
Cheung, J.Y.N.; Ong, R.C.Y.; Suen, Y.K.; Ooi, V.; Wong, H.N.C; Mak, T.C.W.; Fung,
K.P.; Yu, B.; Kong, S.K. Cancer Lett. 2005, 217, 203-211.
Planar Dehydro[8]annulenes and Their Ramifications: Substituted Tribenzo[a,c,e]cyclooctenes and Tetrabenzo[a,c,e,g]cyclooctenes.
Hou, X.-L.; Huang, H.; Wong, H.N.C. Synlett 2005, 1073-1089.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2005; Vol. 17, pp
142-171.
Metabolic studies of clostebol acetate in horses.
Leung, G.N.W.; Ho, E.N.M.; Leung, D.K.K.; Tang, F.P.W.; Wan, T.S.M.; Yeung, J.H.
K.; Wong, H.N.C. Chromatographia 2005, 61, 397-401.
Five-membered heterocycles: furan.
Wong, H.N.C.; Hou, X.-L.; Yeung, K.S.; Huang, H. Modern Heterocyclic Chemistry,
Alvarez-Builla, J.; Vaquero, J.J.; Barluenga, J., Ed.; Wiley-VCH: Weinheim, 2011, Vol.
1, Chapter 6, pp 533-592.
Leung, G.N.W.; Ho, E.N.M.; Leung, D.K.K.; Tang, F.P.W.; Yiu, K.C.H.; Wan,
T.C.M.; Xu, X.; Yeung, J.H.K.; Wong, H.N.C. In Proceedings of the 15th International
Conference of Racing Analysts and Veterinarians; Albert, P.H.; Morton, T.; Wade, J.F.,
Eds.; R. & W. Communications: Newmarket, Suffolk, 2005, pp 146-154.
Use of silicon substituents in the synthesis of natural and non-natural molecules.
Wong, H.N.C. Chin. J. Chem. 2005, 23, 1106-1108.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2007; Vol. 18, pp

197.
198.
199.
200.

201,
202.
203.
204.
205.

206.
207.

208.

209.
210.

187-217.
Total synthesis of ()-Pallavicinin and ()-Neopallavicinin.
Peng, X.-S.; Wong, H.N.C. Chem. Asian J. 2006, 1, 111-120.
Synthesis of enantiopure (S,R,S)- and (R,S,R)-1,4,5,8,9,16-hexahydroxytetraphenylenes.
Wu, A.-H.; Hau, C.-K.; Wong, H.N.C. Adv. Synth. Catal. 2007, 349, 601-608.
Synthetic studies towards plakortide E: application of the Feldman oxygenation to
synthesis of highly substituted 1,2-dioxolanes.
Zhao, Q.; Wong, H.N.C. Tetrahedron 2007, 63, 6296-6305.
Synthesis, characterization and reactions of 6,13-disubstituted 2,3,9,10-tetrakis(trimethylsilyl)pentacene derivatives.
Wang, Y.-M.; Fu, N.-Y.; Chan, S.-H.; Lee, H.-K.; Wong, H.N.C. Tetrahedron 2007, 63,
8586-8597.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2008; Vol. 19, pp 176-207.
Furans and benzo derivatives: reactivities.
Yeung, K.S.; Yang, Z.; Wong, H.N.C. Comprehensive Heterocyclic Chemistry III;
Jones, G.; Ramsden, C.A., Volume Ed.; Elsevier: Oxford, 2008, Vol. 3, pp 407-496.
Metabolic studies of mesterolone in horses.
Ho, E.N.M.; Leung, D.K.K.; Leung, G.N.W.; Wan, T.S.M.; Wong, H.N.C.; Xu, X.-H.;
Yeung, J.H.K. Anal. Chim. Acta 2007, 596, 149-155.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2009; Vol. 20, pp 152-189.
To flip or not to flip? Assessing the inversion barrier of the tetraphenylene framework
with enantiopure 2,15-dideuteriotetraphenylene and 2,7-dimethyltetraphenylene.
Huang, H.; Stewart, T.; Gutmann, M.; Ohhara, T.; Niimura, N.; Li, Y.-X.; Wen, J.-F.;
Bau, R.; Wong, H.N.C. J. Org. Chem. 2009, 74, 359-369.
Biomimetic total synthesis of ()-pallavicinolide A.
Dong, J.-Q.; Wong, H.N.C. Angew. Chem. Int. Ed. 2009, 48, 2351-2354.
Hydroxytetraphenylenes, a new type of self-assembly building blocks and chiral
catalysts.
Huang, H.; Hau, C.-K.; Law, C.C.M.; Wong, H.N.C. Org. Biomol. Chem. 2009, 7,
1249-1257.
Isolation, characterization, molecular cloning and modeling of a new lipid transfer
protein with antiviral and antiproliferative activities from Narcissus tazetta.
Ooi, L.S.M.; Tian, L.; Su, M.-X.; Ho, W.-S.; Sun, S.S.M.; Chung, H.-Y.; Wong,
H.N.C.; Ooi, V.E.C. Peptides 2008, 29, 2101-2109.
Five-membered ring systems - furans and benzofurans.
Hou, X.-L.; Yang, Z.; Yeung, K.S.; Wong, H.N.C. Progress in Heterocyclic Chemistry;
Gribble, G.W.; Joule, J., Eds.; Pergamon Press: Oxford, 2009; Vol. 21, pp 179-223.
Total synthesis of plakortone B.
Xie, X.-G.; Wu, X.-W.; Lee, H.-K.; Peng, X.-S.; Wong, H.N.C. Chem. Eur. J. 2010, 16,
6933-6941.

211. Synthesis and photophysical studies of chiral helical macrocyclic scaffolds via
coordination-driven self-assembly of 1,8,9,16-tetraethynyltetraphenylene. Formation of
monometallic platinum(II) and dimetallic platinum(II)-ruthenium(II) complexes.
Lin, F.; Peng, H.-Y.; Chen, J.-X.; Chik, D.T.W.; Cai, Z.; Wong, K.M.C.; Yam,
V.W.W.; Wong, H.N.C. J. Am. Chem. Soc. 2010, 132, 16383-16392.
212. Enantioselective Brnsted base catalyzed [4+2] cycloaddition using novel aminosubstituted tetraphenylene derivatives.
Hau, C.-K.; He, H.; Lee, A.W.M.; Chik, D.T.W.; Cai, Z.; Wong, H.N.C. Tetrahedron
2010, 66, 9860-9874.
213. Total synthesis of plakortide E and biomimetic synthesis of plakortone B.
Sun, X.-Y.; Tian, X.-Y.; Li, Z.-W.; Peng, X.-S.; Wong, H.N.C. Chem. Eur. J. 2011, 17,
5874-5880.
214. Furans (Update 2011)
Hou, X.-L.; Peng, X.-S.; Yeung, K.-S.; Wong, H.N.C. Science of Synthesis Knowledge
Update 2011/2012; Ferstner, A., Ed.; Thieme: Stuttgart, 2011; 9.9.5, pp 261-370.
215. A concise synthetic approach towards hydroxytetraphenylenes.
Cui, J.-F.; Huang, H.; Wong, H.N.C. Synlett 2011, 1018-1022.
216. Thermotropic liquid crystals based on 1,8,9,16-tetrasubstituted tetraphenylenes and their
structure-property relationship studies.
Hau, C.-K.; Chui, S.S.Y.; Che, C.M.; Cheng, P.S.; Mak, T.C.W.; Miao, Q.; Wong,
H.N.C. Chem. Sci. 2011, 2, 1068-1075.
217. Total synthesis of ()-pallambins C and D.
Xu, X.-S.; Li, Z.-W.; Zhang, Y.-J.; Peng, X.-S.; Wong, H.N.C. Chem. Commun. 2012,
48, 8517-8519.
218. 2,3,10,11-Tetrahydroxytetraphenylene and its application in molecular recognition.
Cui, J.-F.; Cheng, C.; Gao, X.; Cai, Z.; Han, J.-W.; Wong, H.N.C. Helv. Chim. Acta
2012, 95, 2604-2620. (Dedicated to Professor Dr Dieter Seebach on the occasion of his
75th Birthday)
219. Metabolic studies of 1-testosterone in horses.
Kwok, W.H.; Ho, E.N.M.; Leung, G.N.W.; Tang, F.P.W.; Wan, T.S.M.; Wong, H.N.C.;
Yeung, J.H.K. Drug Testing and Analysis 2013, 5, 81-88.
220. Enantiomeric recognition of amino acid salts by macrocyclic crown ethers derived from
enantiomerically pure 1,8,9,16-tetrahydroxytetraphenylenes.
Cheng, C.; Cai, Z.; Peng, X.-S.; Wong, H.N.C. J. Org. Chem. 2013, 78, 8562-8578.
221. Recent developments and applications of chiral tetraphenylenes.
Han, J.-W.; Chen, J.-X.; Li, X.; Peng, X.-S.; Wong, H.N.C. Synlett 2013, 24, 21882198.
222. Asymmetric synthesis of 3,3,5,5-tetrasubstituted 1,2-dioxolanes: total synthesis of
epiplakinic acid F.
Tian, X.-Y.; Han, J.-W.; Zhao, Q.; Wong, H.N.C. Org. Biomol. Chem. 2014, 12, 36863700.
223. Heteroatom-bridged tetraphenylenes: synthesis, structures and properties.
Xiong, X.-D.; Deng, C.-L.; Peng, X.-S.; Miao, Q.; Wong, H.N.C. Org. Lett. 2014, 16,
3252-3255.
224. Our expedition in eight-membered ring compounds: from planar dehydrocyclooctenes
to tub-shaped chiral tetraphenylenes.

225.
226.
227.

228.
229.
230.

231.
232.

233.
234.
235.

236.

Han, J.-W.; Li, X.; Wong, H.N.C. Chem. Rec. 2015, 15, 107-131.
Tetrathio and tetraseleno[8]circulenes: synthesis, structures, and properties.
Xiong, X.-D.; Deng, C.-L.; Minaev, B.; Baryshnikov, G.V.; Peng, X.-S.; Wong, H.N.C.
Chem. Asian J. 2015, 10, 969-975.
Brnsted acid-catalyzed synthesis of carbazoles from 2-substituted indoles.
Li, Q.-J.; Peng, X.-S.; Wong, H.N.C. Org. Chem. Front. 2014, 1, 1197-1200.
Antiviral activity of Chinese medicine-derived phytochemicals against avian influenza
A (H5N1) virus.
Ooi, V.E.C.; Chan, P.K.S.; Chiu, L.C.M.; Sun, S.S.M.; Wong, H.N.C. Hong Kong Med.
J. 2014, 20 (Suppl 4), S37-S41.
Gold(I)-catalyzed domino cyclization towards synthesis of tricyclic chromones.
Li, Z.-Q.; Li, Q.-J.; Liu, G.-K.; Chen, W.-M.; Peng, X.-S.; Wong, H.N.C. Synlett 2015,
26, 1461-1464..
Synthesis and application of [3.3.0]furofuranone in total synthesis.
Peng, X.-S.; Ylagan, R.M.P.; Siu, Y.M.; Wong, H.N.C. Chem. Asian J. 2015, 10, 20702083.
Polycyclic arenes containing 8-membered carbocycles.
Deng, C.-L.; Peng, X.-S.; Wong, H.N.C. Polycyclic Arenes and Heteroarenes:
Synthesis, Properties, and Applications; Miao, Q., Ed.; Wiley-VCH: Weinheim, 2015;
Chapter 5, pp 111-141.
Double helical oligotetraphenylenes: synthesis, structures and chiroptical properties.
Chen, J.-X.; Han, J.-W.; Wong, H.N.C. Org. Lett. 2015, 17, 4296-4299.
Tetraphenylene-based homooxacalixarenes: synthesis, structure, and complexation with
fullerenes.
Deng, C.-L.; Xiong, X.-D.; Chik, D.T.W.; Cai, Z.; Peng, X.-S.; Wong, H.N.C. Chem.
Asian J. 2015, 10, 2342-2346.
Iron-catalyzed cross-coupling of organolithium compounds with organic halides.
Jia, Z.-H.; Liu, Q.; Peng, X.-S.; Wong, H.N.C. Nat. Commun. 7:10614 doi:
10.1038/ncomms10614(2016).
Palladium-catalyzed double Ullmann reaction: a new approach towards tetraphenylenes.
Li, X.; Han, J.-W.; Wong, H.N.C. Asian J. Org. Chem. 2016, 5, 74-81 (Cover Paper)
Structure and spectroscopic characterization of tetrathia- and tetraselena[8]circulenes as
a new class of polyaromatic heterocycles.
Minaeva, V.A.; Baryshnikov, G.V.; Minaev, B.F.; Karaush, N.N.; Xiong, X.-D.; Li, M.D.; Phillips, D.L.; Wong, H.N.C. Spectrochim. Acta Part A Mol. & Biomol. Spect.
2015, 151, 247-261.
Total synthesis of ()-gracilioether F.
Shen, X.-Y.; Peng, X.-S.; Wong, H.N.C. Org. Lett. in press.