Professional Documents
Culture Documents
clear,
colorless
and
CAPSULE SIZES
SIZE
AMT (gr)
000
15
00
10
7.5
METHODS
1.)PUNCH METHOD
-used in hard-gel capsules
-The ingredients are triturated to
the same particle size and then
mixed by geometric dilution.
2.)CAPSULE FILLING METHOD
-used in soft-gel capsules
-capable of filling 2000 capsules
per hour. Useful for clinical drug
trial
lots
production.
and
small
scale
microcrystalline
2.)DISINTEGRANTS
-frequently added to assist the
breakup and distribution of the
capsules content in the stomach
EXPERIMENT PROPER
-ex.
Pregelatinized
croscarmellose,
sodium
glycolate
ASPIRIN
starch,
starch
-Uses:
Antidiuretic;
Prevents
transient ischemic attack (TIA)
POST-LAB
EXAMPLES OF
DISINTEGRANTS
DILUENTS
AND
1.)DILUENTS/FILLERS
- Improved plug formation and
compression
-Often provides cohesion to the
powders, which is beneficial in the
LIQUID
INGREDIENTS
be placed in capsules I
the usual manner.
and added.