ACCESSION NO

PROTEIN

SPECIES

SEQUENCE

>tr|Q962Y6|Q962Y6

Thioredoxin glutathione reductase

Schistosoma mansoni

MPPADGTSQWLRKTVDSAAVILFSKTTC
KCLASFSKIETVPQMFVRGKFIGDSQTVL
AAGKEAAKYGAKTAVLDYVEPTPIGTTW
FGWSLDRSKISHNWSTMVEGVQSHIGS
KNQKVSTITGNKIILATGERPKYPEIPGAV
CAGFLASLGGDVTVMVRSILLRGFDQQ
ENNKPGLLLVKGHYTDGKKFEEEFETVIF
EQTTVSNVYAIGDINAGKPQLTPVAIQAG
ACGLSEEDAIEKYGDKDIEVYHSNFKPLE
GPNAGEITQGYAVAIKMGATKADFDRTIG

>tr|B5THG7|B5THG7

Thioredoxin glutathione reductase

Schistosoma japonicum

MPPIDGTSQWLQRTIESAAVIVFSKTTCP
KALSNFSKIETVPQMFVRGKFIGDSKAVL
AAGKEAAKYGAKIAVLDYVEPTPMGTTW
FGWSLDKSEISHDWSTMVEGVQSHIGS
KNKKVSTITGNKIILATVERPKYPEIPGAIE
CAGFLASLGGDVTVMVRSILLRGFDQQ
ENNKPGLLLVKGHYTDGKKFEEEFETVIF
EQTTVSNIYAIGDINAGKPQLTPVAIHAGR
ACGLSEEDAIEKYGDNDIEVYHSHFKPLE
GPNAGEITQGYAVAIKMGATKEDFDRTIG

>tr|F8QQF4|F8QQF4

Thioredoxin glutathione reductase

Echinococcus granulosus

MFGCHCLRRACTPLSAIACFFNPRRTAM
CKKVMERFNNLKIPFGYLDLDLKKNGSD
IDDDTIVKKANEMKYDYDMVIIGGGSGG
GTCVNVGCIPKKLMHQAALLNHYMEDA
SSMMNANVKYLNALGEIVDPHTIKTTNK
ITSDDLFTLDHNPGKTLCVGASYVSLECA
DYIAKYGVKFVRPCVPTSVRCLEEYDPES
DPCTTNIGLQNVDVKTTNGRVVVDDEE
RLYTADDCRTDYTNVPTTVFTPLEYGCIG
RPDNTCYAKLIINKQDDNRVVGFHVFGP
SETFTTLRVTKSSGASATVTGCUG

>tr|A0A087W1F1|
A0A087W1F1_

Thioredoxin glutathione reductase

Echinococcus multilocularis

MERFNNLKIPFGYLDLDLKKNGSDYQKM
TIVKKANEMKYDYDMVIIGGGSGGLALA
NVGCIPKKLMHQAALLNHYMEDAKSFG
NANVKYLNALGEIVDPHTIKTTNKQGIVK
DLFSLDHNPGKTLCVGASYVSLECAGFL
KYGVKFVRSCVPTSVRCLEECDPESGKP
TNIGLQNVDVKTTNGRVIVDDEERTNVP
ADDCRTDYTNVPTTVFTPLEYGCIGLSEE
TCYAKLIINKQDDNRVVGFHVFGPNAGE
TTLRVTKSSGASATVTGC

Fasciola hepatica

MAPIPDDTSSWVKKTINSSAVLLFSKSRC
QQVLSQISGISTVPQVFVRGEFVGDSST
LAASKEAARFGAKTAVFDFVVPTPQDTT
HFGWKWDPEKIEHDWAQIVENIGNHIH
KKNKETGTVTAKVIILATGERPRYPGIPGD
ECAGFLTRFGFDTTVMVRSIFLRGFDQQ
KENQKPGLYRVKGKYENGEEFVGEFNTI
NEQSSVDSIYAIGDIVSGKPQLTPVAIHAG
GACGLSEEDAITKYGKENIEVYHSHFIPL
GPNAGEMTQGFSVAMKAGATKADFDRT

Fasciola gigantica

MLRAVNGVTSCSDNQPMSSKMVPIPDD
DDKINHAVIELDKRPDGAKIQQVLSQISG
VIKKNTYDYDLVVIGGGSGGLAASKEAA
IPKKLMHQAALLREGMSDSVHFGWKWD
NVEYVNAFAEVVDPHTIKYTKKNKETGT
FWLPYPPGKTLVVGASYVALECAGFLTRF
GTKFVRSCVPTVIEEIEPRDKENQKPGLY
KAMESVGLRLDKAKRVVCADNEQSSVD
DIELTDYVNVPTTIFTPIEYGACGLSEEDA
YAKIICLKSDSERVIGLHVLGPNAGEMTQ
MHVTKASGASAKVTAC

>tr|A8E0R8|A8E0R8_

>tr|A0A0K1NYF8|
A0A0K1NYF8_

Thioredoxin-glutathione reductase

Thioredoxin-glutathione reductase 1

>tr|G7YV41|G7YV41

Thioredoxin reductase (NADPH)

Clonorchis sinensis

MHRYSTNKVSELNERTRLDLATREEGQF
PWHNPAKLSYSTLSLWLWCSMAQHELK
SADNNRIHYNSTVRMFLSVKLILVTQIIVS
VFLRSSLLQELMTDKANQASLAGLCREY
NIRFSPSDADEHISMPARPQHSRLIICFD
SAFLVFILLQALELRHFEIRLPELRGGFDE
RSEIRIHSKSQKGADMMSEKTIGMNRAA
GVPQSSVLRRLMSLIFLCLLIRQPVVPDC
MRVFYPDCLNGCLEKELKEDQTYETDTE
GREQLRVRYQTGERRLCPRKFKIEQINRT
YPTRPEKYPRPYIGFVPTLRIPLANWKYSA
PSCSNERLTSSRSEAVVGYRTPIATFCFN
YYEIASRPRKPWHLTESSETYRLCDSSKV
LAASKEAAIFGAKTAVLDFVKPTPKNTVW
KFGWDIKKDEVKHDWEKMVEGIQNHIH
KKSGETSTITTNKMILAMGERPRYPDIPG
ECAGFLTSLGYDTTVMVRSILLRGFDQQ
LEKGKTGRYRVTAKYSDGKPFSEEYNTIIF
DEQTSLDNIYAIGDINAGKPQLTPVAIQAG
GAIGLSEEDAIAKYGKENITVYHSHFNPL
LGPNAGEITQGYAVAMKIGVTKADFDAT
RGHAKSYRLLRLIPYRNAYLVFSTKRGTT
RFLNERCEICSLEYKAKHLEKPESKNVSE
NNTPIVMVNRWWVEICDFYGRLPRFDE
CDIFGLHILDHLTPFNSPFILQQCKRATSN
LPSANLLRN

>tr|E1FN41|E1FN41

Thioredoxin reductase

Loa loa

MWYSRMHIRCLTSWYTMRGGVNVKILE
NRSARELSMPPTSNLVISGAAASAVFKS
TVRVSNDAVKSVLEIVGWPSMPLIFVKG
GGGSGGLAAAKEAVRLGKKVVCLDFVK
YIEDAKKFGWEIPEGAIKLNWHQLKNAIQ
HELSVKNKKGKVEKVTADRFLIAVGLRP
ASYVSLECAGFLRGIGNDVTVMVRSILLR
LKEPTNNEPGLIRVHTVQEREDGTKEEV
GKIIGRREQSVSCPYVYAIGDVLHGSPEL
VFTPLEYGSCGLSEDAAIQKYGKENINVY
DLVLGFHILAPNAGEITQGFAIALKFDAKK
KATGC

>tr|A0A095B2S5|
A0A095B2S5

Thioredoxin reductase 1

Schistosoma haematobium

MSLADSCFLRVVNCHDMRSMPHTYGTQ
NGSAIQKSLASFSKIETVPQMFVRGKFIG
GGSGGLAAGKEAAKYGAKTAVLDFVEPT
LLISVSHNWSTMVEGVQSHIGSLNWGY
SIITGDKIILATGERPKYPEIPGAVEYGITS
ASLGGDVTVMVRSILLRGFDQQMAEKIK
TVIFAVGREPQLSKVLCTTVGVKLDKDG
IQAGRYLAKRLFAGATELTDYSNVATTVF
KPLEWTVAHREDNVCYMKLVCRKSDVS
DNAFWHLLFVRVCQINLVKASFRNFKNS

Ascaris suum

MMITPLKRSTRKTDGRIIRREQTEEREQE
QPTTLQYFQGRAVKERKAEASEESAGVE
ERDAELQKITDILTNRNETVELLKISHVAA
LEESGALNEWLKEHNYDLVVIGGGSGG
TCVNVGCIPKKLMHQAALLGEYIGDAKK
RVQLRERSVTYSNAYGVFTGSHELTTTN
CISSDDLFSLTYNPGKTLCVGASYVSLEC
RRHMMTHEIKFINAVPTKYERIEEPADDK
GRDAVTDEMGLELVGVERTKSGKIVGRR
MRRLITGNSELTEYDQVPTTVFTPLEYGC
PERVENSHCYCKLICLKTEQDLVLGYHILA
PTVAENLTTLTLVKEEGQQLKASGC

Trichinella spiralis

MPPVDNVKKPQNLGSLLELIFNSKTITVV
DKDRVLRYLFDISCRNLLPLIFVNGDCVG
SGGLAAAKDAALAGKRVAVLDFVTPTPL
DARKFGWKYGEEVKHSWTDMVTAIQSH
ATDKRNKEQIITSDRFIIATGLRPRYLDVP
SLECAGFLRGLGLDVTVMVRSILLRGFD

>tr|F1KTQ5|F1KTQ5

>tr|E5S1L9|E5S1L9

Thioredoxin reductase 1

Thioredoxin reductase 1

DGQPGLFRVTAKKEDGEEVVDEYNTVL
EQSTTAPYIYAIGDVLDRGLELTPVAIKAG
GCCGMSEEEAIEEYGEINIEVFHSYFTPL
LLGPNAGEITQGFAIGLKLKATKHDFDLL
>tr|A0A0B1S3D4|
A0A0B1S3D4

Thioredoxin and glutathione reductase

(Fragment)

Oesophagostomum
dentatum

>tr|A0A0J9XPT5|
A0A0J9XPT5

BRUMA BMA-TRXR-1, isoform b

Brugia malayi

MISVGLLFLGIFRNAQAYLLRSNATDKRS
ACEERILLAYADYNPDMTKVVNLFSKYNE
NCCGGFKELYQLEESGFLNEWLKEHEYD
SAMGTTWGLGGTCVNVGCIPKKLMHQA
QNHIASLNWGYRVQLKEKSVTYMNSYAT
RFPDVPGALECCISSDDLFSLPYNPGKTL
RGFDQDMAERIKKHMTERGVKFVQCVP
EDFNTVLMAIGRDAMTDDLGLDVVGVN
TPVAIQAGKVLMRRLFTGSSELTEYDKIP
HNVFIPLEYAVTERKEKTHCYCKLICLKNE
KADFDRLIGIHPTVAENFTTLTLVKEDGQ

Echinococcus granulosus

MAPIGGSAEQVEKLRNKINNAAVLVFAK
DYQKMLQEITGRTTVPQVFFRGEFIGGC
GLALAKESAKSGAKVALLDFVVPTPMGT
KSFGWDVDKGPHDWVKMVEGIQDHIH
KQGIVKNITTNTIIVATGERPRYPPIPGAKE
CAGFLSSIGCDVTVMVRSIFLRGFDQQM
ESGKLAIYEVEGKHEDGTPFKDTFNTVL
RTNVPNIYAIGDVSNAGYQLTPLAIQAGK
IGLSEENAISKFGEDNIEVFHSYFQPLEW
PNAGEVTQGYAVAMHLGARKEDFDRTIG

>tr|Q869D6|Q869D6

Thioredoxin glutathione reductase

LHFNSLSINGFHSTAQFQVTYINSYGVFT
YPENTPGVREYTITSDDLFSLPYPPGKTL
RGFDQDMAERIRRQMTEYGVKFVGAVP
SEEFDTVVMAIGRDAVTKDIGLNVPGVE
LTPVAIQAGKVLMKRLYGGADDLTEYDD
YHGVFFPLEYTVAERAEKEHCYCKLICLK
TKADFDRLIGIHPTVAENFTTLYLVKKEGE

>tr|A0A068X253|
A0A068X253

Thioredoxin glutathione reductase

Hymenolepis microstoma

MSCIVRYFNLLSQRTSMPPTGSSLEKVEK
KIPYGSLELDLKKNGAEYQAMLKDITGRT
EMKYDYDMVIIGGGSGGLALAKQSAKSG
KLMHQAGLLNHYLEDAESFGWGLKREE
NALGEIVDPHTVKTTNKQGIVKNITANTIV
SPGKTLCVGASYVSLECAGFLKSIGYDVT
RPCVPTSIKCLDEGDAETKKLPVYEVEAK
VDVKVDSNHRIIVDEEERTNVSNIYAIGD
DYNNVPTTVFTPLEYGSIGFSEEVATEVF
IVNKTDDNRVVGFHVLGPNAGEITQGYA
KSSGQSPKVTGC

>tr|A0A068AVN2|

Thioredoxin glutathione reductase

Dugesia japonica

MPPVSSELKLWVEQTIKSSVMIIFSKTTCP
QDILFQLTNQKTVPNVFVRGTHIGGCDN
LAASKEASNFGAKVAVLDFVQPTPMGTT
SYGWNIPEKLEHNWENMVTEIQNHIQSL
KYNSTREITSDKFLIATGERPKYPDIPGDK
CAGFIAALGGKVTVMVRSIFLRGFDQQM
GKKEVFGSYVKNNNEYKDWFNTVLFAIG
VENVYAIGDIISGGLQLTPVAIQAGKNLAR
PEEDAISKFGAENIEVFHQNFKPLEWTVA
GEITQGYAVAMRMGATKRDFDDTIGIHP
MSLADSCFLRVVNCHDMRSMPHTYGTQ
ASFSKIETVPQ
MFVRGKFIGDSQMVLKYHRNNELTSIVN
GTTWGLGGTC
VNVGCIPKKLMHQAGLLTLCLLISVSHNW
HEVQITDKNQKV
SIITGDKIILATGERPKYPEIPGAVEYGITS
SILLRGFD
QQMAEKIKQLKAVDTENNKPGLLLVKGH
VVCTDDEQTTV
SNVYAIGDINAGKPQLTPVAIQAGRYLAK
DIEVYHSNF
KPLEWTVAHREDNVCYMKLVCRKSDVS
VCQINLVKA
SFRNFKNSKLAYH

>gi|844874400

Thioredoxin reductase 1

Schistosoma haematobium

>gi|913075154

thioredoxin-glutathione reductase 1

Fasciola gigantica

>gi|913075156|

thioredoxin-glutathione reductase 2

Fasciola gigantica

>gi|576699733

Thioredoxin reductase 3

Echinococcus granulosus

>gi|358255107

thioredoxin reductase (NADPH)

Clonorchis sinensis

MLRAVNGVTSCSDNQPMSSKMVPIPDD
ELDKRPDGAKI
QQVLSQISGISTVPQVFVRGEFVGDSSM
GAKTAVFDFV
VPTPQDTTWGLGGTCVNVGCIPKKLMH
HSLNWGYRTQLRSI
NVEYVNAFAEVVDPHTIKYTKKNKETGT
VGASYVAL
ECAGFLTRFGFDTTVMVRSIFLRGFDQQ
RVKGKYENGEE
FVGEFNTIVMAIGRDPTWDRKAMESVG
GRYLARRLYAG
DIELTDYVNVPTTIFTPIEYGACGLSEEDA
VIGLHVL
GPNAGEMTQGFAVAMKAGATKADFDRT
MRVVVFGFGGMHCFQRFYSVSRISRLC
SKSRCPYCRAVKQ
IFNDDKINHAVIELDKRPDGAKIQQVLSQ
YDLVVIGGG
SGGLAASKEAARFGAKTAVFDFVVPTPQ
WKWDPEKIEHDWAQ
IVENIGNHIHSLNWGYRTQLRSINVEYVN
DKEYAITS
DDLFWLPYPPGKTLVVGASYVALECAGF
RSCVPTVIEEIE
PRDKENQKPGLYRVKGKYENGEEFVGEF
SVDSIYAIGDIVS
GKPQLTPVAIHAGRYLARRLYAGDIELTDY
WTVPHRP
EDGYAKIICLKSDSERVIGLHVLGPNAGE
GASAKVTAC

MGTLIKTCKSLLKKTTQCDQSMSITRISTE
VLVFAKSFCPYCKKVMERFNNLKIPFGYL
M
AIDDDTIVKKANEMKYDYDMVIIGGGSG
GCI
PKKLMHQAALLNHYMEDAKSFGWDVD
GEIVD
PHTIKTTNKQGIVKNITTNTIIVATGERPRY
GFLSSIGCDVTVMVRSIFLRGFDQQMAG
G
KHEDGTPFKDTFNTVLFAVGRDPCTTNI
P
LAIQAGKNLARRLYTADDCRFSLPSNMA
Y
AKLIINKQDDNRVVGFHVFGPNAGEVTQ
A
TVTGC
MHRYSTNKVSELNERTRLDLATREEGQF
SY
STLSLWLWCSMAQHELKEQSAPQTAYLL
LILVTQIIVSVRFLPLTRLHTAARIILLTQSA
TKSLMWLNVPESNHSTAMDSRLNSKLIC
S
SKTMAYYPYMYCAIGEWMMVSAFLVFILL
G
PAVDHAEKVKRSEIRIHSKSQKGADMMS
SI
GVPQSSVLRRLMSLIFLCLLIRQPVVPDC
N
GCLEKELKEDQTYETDTENRFKIARNSE
RK
FKIEQINRTRIRKSSVVVAGVPSNKAKEF
AHRIAHPNPITSNITSVTRLGVLMQVHHW
VKKVAKSGFIRLYGPHRLRKYYEIASRPR
LVVIGGGSGGLAASKEAAIFGAKTAVLDF
E
KFGWDIKKDEVKHDWEKMVEGIQNHIH
T
TNKMILAMGERPRYPDIPGDKEYGITSDD
LLRGFDQQMAEMIGEYMQKHGTKFIRPC
AIGRDPCIDTEMMKRLGIKLDKANRVICE
STELTDYVNVATTVFTPIEYGAIGLSEEDA
ANEQVLGFHVLGPNAGEITQGYAVAMKI
GF
RGHAKSYRLLRLIPYRNAYLVFSTKRGTT
SLEYKAKHLEKPESKNVSEQGFVVIGSV
RLPRFDEITHFSKTYYHDNGFLGMPTDG

KYLPTRDVGQCQSHMSYPDQSKDIQWV