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Department of Rehabilitation, Nursing Science and Sport, Rudolf Magnus Institute, University Medical Center Utrecht, Utrecht,
The Netherlands; 2Clinical Health Sciences, Faculty of Medicine, Utrecht University, The Netherlands; 3The Research Centre for
Innovations in Health-Care, University of Applied Sciences Utrecht, Utrecht, The Netherlands
Objective: To systematically review and summarize the clinimetric properties, including reliability, validity, and
responsiveness, the procedures used, and the meanings of the scores in the Timed Up and Go Test (TUG). The TUG is a
performance test that identifies problems with functional mobility in patients with stroke. Methods: MEDLINE and the
Cochrane Central Register of Controlled Trials were searched from 1991 to January 2013. Studies were included if (1) the
participants were adults with stroke; (2) the research design was cross-sectional, descriptive, or longitudinal and examined
the clinimetric properties, including reliability, validity, and sensitivity to change, and procedural differences in the TUG;
and (3) the study was published in English from 1991 to January 2013. Results: Thirteen studies met the inclusion criteria.
Of these, 4 showed the TUG to have good convergent validity, as it had significant correlations with various instruments.
Three studies that investigated the test-retest reliability showed the TUG to have excellent intrarater and interrater reliability
(intraclass correlation coefficient [ICC] > 0.95). The 3 studies that investigated whether the TUG could predict falls after
stroke showed inconclusive results. Three studies showed the TUG to be sensitive to change, and 1 study showed the TUG
to be responsive in moderate- and fast-walking patients with stroke. However, there were wide variations in the procedures
and instructions used. Conclusion: The TUG can be recommended for measuring basic mobility skills after stroke in patients
who are able to walk. However, the procedures and instructions should be described more clearly. Key words: functional
mobility, psychometric properties, rehabilitation, reliability, stroke, Timed Up and Go test, validity
197
198
Results
The initial search identified 179 studies relevant
to the aims of the review. The titles and abstracts
of these studies were screened if they met the
inclusion criteria, and 33 studies were selected.
After the full text of these articles had been
read, 13 studies met the inclusion criteria and
were included in the review.5,12-23 A flow chart
of the study selection procedure is presented in
Figure 1. Because of the wide variety of study
designs and methods used, it was not possible
to conduct a meta-analysis, and therefore the
results are presented in a narrative manner in
the following sections: (1) characteristics of
the studies; (2) clinimetric properties divided
according to validity, reliability, responsiveness,
and predictive value; (3) application procedures
Table 1.
199
Author, year
10
11
12
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
N/A
1
N/A
1
1
1
1
1
1
1
1
1
1
1
1
N/A
N/A
N/A
1
1
1
1
1
N/A
1
0
0
0
1
1
1
1
0
0
0
1
0
1
1
1
1
N/A
N/A
N/A
N/A
N/A
1
N/A
N/A
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
0
0
0
0
1
0
1
0
0
1
0
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Note: 1= item fulfilled; 0 = item not fulfilled; N/A= item not applicable to study.
1. Thorough literature review to define research question
2. Specific inclusion/exclusion criteria
3. Specific hypotheses (or specific objective/question/aim/purpose)
4. Appropriate scope of psychometric properties (at least 1 psychometric property reported)
5. Sample size calculation/justification
6. Appropriate retention/follow-up
7. Authors referenced specific procedures to administer, score and interpret the procedures
8. Measurement techniques were standardized (within the study)
9. Data were presented for each hypothesis (or question)
10. Appropriate statistics-point estimate
11. Appropriate statistical error estimates
12. Valid conclusions and clinical recommendations
200
PUBMED
175 papers
Cochrane
4 papers
Validity
Reliability
Prospective
longitudinal
study
n = 98 stroke
patients
n = 110 control
subjects
Validity study
N = 44
Simpson et
al, 201122
Canada
Hollands et
al, 201018
UK
Descriptive
study
n = 18
(50% stroke
patients with
fall history)
n = 18 control
subjects
Prospective
study
N = 96
Persson et
al, 201121
Sweden/
Norway
Knorr et al,
201014
Canada
Reliability study
N = 16
Design and
sample
Community dwelling
Community
dwelling; 3 months
after stroke;
follow-up after 5
months
Inpatient
rehabilitation wards;
discharged to their
own homes
Stroke unit;
follow-up at 3, 6, 12
months after stroke
Living at home
Setting follow-up
Differences between
stroke patients and
control subjects in
turning during the
TUG
Convergent validity,
sensitivity to change,
ceiling effect of CB&M
vs TUG, BBS, CMSA
Likelihood of clinical
tests identifying risk of
falling (TUG, 10MWT,
BBS, M-MAS, SPASS)
Reliability of 7
performance-based
tests (walking speed,
stair climbing, TUG)
Objective of the
study
Mean of 3
trials: 2 on the
first day, a third
7 days later.
IntraCC = 0.85;
InterCC = 0.96
Reliability
Significant convergent
abilities between
CB&M and TUG; P <
.001, r = -.75.
Validity
Faria et al,
201223
Brazil
Study
Table 2.
TUG baseline:
16.7 17.1;
follow-up: 13.7
16.0; SRM
0.34; P < .010
SEM of 3 trials,
1.49;
SEM%, 10.94
Responsiveness
Results
Although
participants
with stroke and
fall history took
significantly longer
to turn (mean 4.4
1.7 seconds)
than age-matched
control subjects (2.5
0.6 seconds), no
kinematic differences
were found in
turning performance.
Prediction of falls
Comments
(Continued)
Patients unable to
perform the test are
included as median.
Performed during the
first week after stroke;
all tests had moderate
predictive value.
Decrease in TUG
time follow-up was
associated with
increased risk of
falling.
Day hospital;
patients 3 months
after stroke
Community
dwelling
Descriptive
cohort study
N = 25
Cross-sectional
study
N = 50
Descriptive
study
N = 196
Jnsdttir
and Cattaneo,
20075
Italy
Belgen et al,
200619
USA
Andersson et
al, 200620
Sweden
Stroke unit;
follow-up after 6 or
12 months
Cross-sectional
study
N = 25
Heung and
Ng, 200916
Hong Kong
Community
dwelling;
2-155 months after
stroke
Setting follow-up
Descriptive
study
n = 22
n = 22 control
subjects
Design and
sample
(Continued)
Faria Coelho
de Morais et
al, 200917
Brazil
Study
Table 2.
Prediction of falls
Frequency of falls;
related to self-efficacy
and mobility measures
Differences in time
score of the TUG with
various chair heights
(65%, 90%, 115%
of each subjects leg
length)
Differences in time
score of the TUG
between stroke
patients and control
subjects when side of
turning was compared
Objective of the
study
Reliability
Validity
Responsiveness
Results
Score TUG:
nonfallers, 16.0 7.6;
one-time and multiple
fallers, 19.9 13.9; no
significant difference
PPV 59, NPV 72;
cutoff score TUG
14 seconds
Prediction of falls
Comments
(Continued)
No significant
difference in scores
when turning to
affected or unaffected
side.
Mean difference
between 2 trials: 2.45
(95% CI, 1.10-3.81)
Turning to affected side
significantly faster (P
< .001).
Lowest score when seat
height was 115% of leg
length (27.45 vs 32.25
seat height 65%).
202
TOPICS IN STROKE REHABILITATION/MAY-JUNE 2014
Test-retest
reliability study
N = 50
Cross-sectional
study
n = 11
n = 10 control
subjects
Prospective
cohort study
N = 50
divided into
slow, moderate,
fast walking
(5MWT speed
scores)
Flansbjer et
al, 200513
Sweden
Salbach et al,
200112
Canada
Community dwelling
Setting follow-up
Intra-rater (between
occasions, same day)
reliability study of
performance-based
tests after stroke
(walking speed, stair
climbing, TUG)
Test-retest reliability
of TUG performed on
different days 1 week
apart; association
with plantar flexion,
strength, gait speed
Responsiveness
of gait speed measures
5MWT and 10MWT
comfortable and
maximum speed, BBS,
BI, TUG, STREAM
Objective of the
study
Intra- and
interrater
reliability
Both ICCs >
.95
Reliability
Significant correlation
found between
the TUG and CGS
(-0.86), FGS (-0.91),
SCas (0.86), SCde
(0.90), and 6MWT
(-0.92)
Strength plantar
flexion (P < .01), gait
parameters (P < .05),
walking endurance
(P < .01), significant
association
Validity
Results
SRMs for:
BBS 1.04;
BI .99;
STREAM .89;
TUG .73
SEM 1.14;
SEM% 8.2;
SRD% 23%;
95% SRD, 3.752.59
Responsiveness
Prediction of falls
Reasonably small
improvements are
sufficient to detect real
changes.
Comments
Note: ABC = Activities-specific Balance Confidence Scale; AUC = area under the curve; BBS = Berg Balance Scale; BI = Barthel Index; CB&M= Community Balance and Mobility Scale; CI =
confidence interval; CMSA= Chedoke McMaster Stroke Assessment,; DGI = Dynamic Gait Index; FGS = Fast Gait Speed; 5-10MWT= 5 and 10 Meter Walking Test; GCS = Comfortable Gait
Speed; InterCC = interclass correlation coefficient: IntraCC = intraclass correlation coefficient; IRR = incidence rate ratio; MMAS = Modified Motor Assessment Scale; NPV = negative predictive
value; PVV = positive predictive value; SCas = stair climbing ascending; SCde = stair climbing descending; SEM = standard error of measurement; SEM% = limit for the smallest changes that
indicate real improvement; 6MWT = 6 Minute Walk Test; SPASS= Swedish Postural Assessment Scale for Stroke Patients; SRD = smallest real difference; SRM = standardized response mean
(= mean change divided by standard deviation of change); STREAM= Stroke Rehabilitation Assessment of Movement.
Design and
sample
(Continued)
Study
Table 2.
n = 80 stroke patients
living at home
n = 90 control subjects
Faria Coelho
de Morais et al,
2009 17
Brazil
Hollands et al,
201018
UK
N = 25
patients with subacute
stroke
n = 22 control subjects
n = 18 control subjects
n = 22
2-155 months after
stroke, community
dwelling
Armchair,
no specifications
reported
Not reported
N = 96
Assessment first week
after stroke
Persson et al,
201121
Sweden/
Norway
Simpson et al,
201122
Canada
N = 44
3 months
after stroke;
follow-up
after 5 months;
community dwelling
n = 18
stroke patients with and
without falls,
community dwelling
N = 16
Stroke patients living at
home
Faria et al,
201223
Brazil
Knorr et al,
201014
Canada
Chair
Turning at mark on
the floor; walking
as fast and safely as
possible
Not reported
Sit comfortably; on
command, go; selfselected speed; turn
around; walk back;
sit down
Walk as fast and
safely as possible;
turning point
marked by tape
Stand up, walk 3 m,
turn around, walk
back, and sit down
Instruction
2 trials to become
familiar; first
trial, turn toward
preferred side;
second, turn
toward opposite
side
2 trials to become
familiar (seat
65%); 3 trials
timed and 1-min
rest between trials
Not reported
First time, 2
assessments;
second
assessment after
7 days
Not reported
how many times
the test was
performed
Not reported
Procedure
Inclusion when
patients could walk
unassisted
Inclusion only
when patient could
perform the test.
n = 2 at baseline;
in follow-up, all
patients could
perform the test.
n = 28
The Timed Up and Go Test: Procedures and scores as described in the studies included
Study
Table 3.
Walking without
assistance or walking aid;
number of patients
walking with device not
reported
(Continued)
Scores
204
TOPICS IN STROKE REHABILITATION/MAY-JUNE 2014
N = 159
patients treated in a
stroke unit;
follow-up after 12
months
N = 50
6-46 months
after stroke;
community
dwelling;
able to walk
n = 11
5.6 3.3 years
after stroke
n = 10 control subjects
N = 50
patients with acute
stroke;
follow-up after 4 weeks
Andersson et
al, 200620
Sweden
Flansbjer et al,
200513
Sweden
Salbach et al,
200112
Canada
Armchair;
no specification
reported
Height 44 cm;
depth 45 cm;
width 49 cm;
armrest height
64 cm
No specifics
reported
Walk 3 m as fast as
possible, cross a line
on the floor, turn,
walk back, and sit
down
Rise, walk 3 m at
usual pace, turn
around, walk back,
and sit down
Armchair
height not reported
Armchair
height not reported
Not reported
No specification
reported
N = 25
3 months
after stroke;
able to walk
N = 50
62.2 62.1 months after
stroke
Jnsdttir
and Cattaneo,
20075
Italy
Belgen et al,
200619
USA
Instruction
Chair
(Continued)
Study
Table 3.
Examiner stands
to the side while
timing
TUG performed
once
(TUG score
related to falls)
Not reported
Procedure
n = 10 not able to
perform the test at
baseline;
n = 3 after 4 weeks.
Inclusion only
when patient could
walk and perform
the test.
Inclusion only
when patient could
walk and perform
the test.
Inclusion only
when patient could
walk and perform
the test
Inclusion only
when patient could
walk and perform
the test
n = 32 no walking aid
n = 7 used ankle- foot
orthesis
Not reported
Healthy subjects:
9.1 1.6 seconds
Stroke patients:
22.6 8.6 seconds
P < .001
26.2 17.3 seconds
Follow-up: 19.6 17.5
seconds
Scores
206
Walking aids
207
208
209
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