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I.
OBJECTIVES
At the end of the lesson 100% of the students shall be able to attain 80% level of
proficiency to:
1) Explain genetic phenomena using the concepts of multiple alleles.
2) Solve simple blood typing problems and realize its importance.
II.
SUBJECT MATTER
A. Topic: Non-Mendelian Patterns of Heredity (Multiple Alleles)
B. Concept: Multiple alleles is a pattern of inheritance when a gene may have more than
two alleles for any given traits.
Example:
Type 0
(ii)
Type A
(IAIA
,IAi)
Human
Blood
Type
Type
AB
(IA IB)
Type B
(IBIB,IBi)
TEACHING PROCEDURES
A. Routinary Activities
1. Prayer
2. Greeting of the class
3. Checking of attendance
4. Checking of assignment
B. Developmental Activities
Teachers Activities
1) Motivation.
Before we start our lesson, lets have a game. I will
group you into two. Each group will be given an envelop
with jumbled letters inside. I want you to form it into 2
words. I will give you a clue regarding that words and
the first group who will answer my question correctly
will be declared the winner. Is the instruction clear class?
Pupils Activities
Yes Maam.
2) Lesson Proper
All along we have been talking about traits that have been
determined by only two different alleles. Its true, each of
us have two alleles for each gene, but geneticists
discovered that there some traits that are not controlled
only by two alleles but by multiple alleles.
What is your idea about multiple alleles? Anyone from
the class?
Thats correct! From the word itself, multiple, meaning
more than 2. Therefore, multiple alleles is a pattern of
inheritance when a gene may have more than two alleles
for any given traits. The expression of character is still
controlled by one gene pair, but the gene has three or
more alleles. For example, its not just black and white,
not just white and green, but maybe black, white and
green or green, brown and red.
An example of multiple allelism is the inhereitance of
human blood ABO blood type. A, B, AB and O. Three
alleles control this character, the A, B, and O.
Objectives:
1) Explain genetic
phenomena using the
concepts of multiple
alleles.
2) Solve simple blood typing
problems and realize its
importance.
Sample Problem:
A woman with type AB blood is married to a type O man,
What are the chances that their child will have type AB or
type O blood?
Keys: IAIB type AB
ii type O
P1: IAIB x ii
IA
i
IAi
i
IAi
A
B
GR: 2 I i; 2 I i
PR: 2 type A: 2 type B
IB
IB i
IB i
P1 : IAIB x IAIB
IA
IB
IA
IAIA
IAIB
IB
IAIB
IB IB
IB
IA IB
IB IB
IB
IB IB
IB IB
IA
IA IB
IA i
IB
IB IB
IB i
V: GENERALIZATION
Let us have a summary of what we discussed today.
Please fill in the blanks.
IV.
EVALUATION.
Choose the letter of the correct answer.
1) How many genotypes are possible for a person with blood type A?
a) 2 possible genotypes, namely IAIA and of IAi.
b) 1 possible genotype, which is IAIA.
c) 3 possbile genotypes, namely IAi, IAIA, and IAIB
d) None of the above.
2) What is the phenotype of a person with genotype IAi?
a) Blood type B.
b) Blood type A.
c) Blood type O.
d) Blod type AB.
3) What is the phenotype of IAIB?
a) Blood type A
b) Blood type B
c) Blood type AB
d) Blood type O.
4) If i is combined with any of the other alleles, will it be physically expressed?
a) Yes
b) No
5) Can a couple with both husband and wife having blood type A, produce a child with
blood type O?
a) Yes, provided that they have heterozygous genotype, IAi.
b) No, they will not produce a child with blood type O since they are both blood type A.
c) None of the above.
Answer Key:
1) A
2) B
3) C
4) B
5) A
V: ASSIGNMENT:
A paternity case involves these facts: a woman is A, her child is O, and the alleged father is
B. Could he be the father? Explain.
Answer: Yes, provided that the mother is IAi and the father is IBi.
Prepared by:
Donna L. Domingo, R.N.
CTP Batch IX (Biological Science)