THE

Sales Agent Michael Dietrick

http://synergyscience.com/#agent=1176

Paul A. Barattiero, C.Ped.

Copyright 2013. Synergy Science, Inc. All Rights Reserved.
800-337-7017 - info@echowaterionizer.com - www.echowaterionizer.com
Water is the most common substance on earth however, one of the least understood.

Not a day goes by that water is not a part of our life. We drink it, cook with it, bathe in it, swim in
it, give thanks for it when it rains and play in it when it snows. There is no
doubt that water is an integral part of each of us and the world we live in.
Water (H2O), which is essential to life, is formed by the combination of
oxygen (a powerful oxidizer and essential for life) and hydrogen (a powerful
reducer and essential for life). Molecular hydrogen (H2) is considered the
primordial anti-oxidant. Oxygen (O2) is a well-known oxidant. Hydrogen was
involved in the genesis of life and oxygen is necessary for the existence of
life. We breathe in oxygen (an oxidizer) all the time pushing our bodies
towards oxidation. Consuming hydrogen is the perfect and natural way to
balance the oxidation from oxygen. Echo water contains dissolved
molecular hydrogen or diatomic hydrogen. Drinking Echo water is the
easiest and most logical delivery method of obtaining the H2 antioxidant.

Consider the following thoughts:

If the gut biome is healthy, you can produce up to 10 liters of hydrogen gas per day.
H2 combines with Hydroxyl radicals (most cytotoxic free radical into water molecules).
H2 stimulates gastric Ghrelin secretions which increases cognitive function. Helps Autism,
Parkinsons, Alzheimers, Bipolar, Schizophrenia,
Oxidative stress is thought to be the leading cause of disease.
H2 reduces oxidative stress and inflammation.
H2 has been shown in to greatly reduce Rheumatoid
Arthritis and joint issues.
600 studies showing therapeutic benefits in 150+
human disease models and every organ in the body.

Now that you are thinking about how amazing hydrogen is,
lets discover how Echo Water which is hydrogen enriched water can help you. Molecular
hydrogen has tremendous benefits. Peer reviewed scientific studies have shown molecular
hydrogen significantly helps oxidative stress, inflammation, Rheumatoid Arthritis, Diabetes, Colon
Cancer, Autoimmune, Parkinsons, Alzheimers, Autism, Bipolar, Schizophrenia, fatigue when
participating in physical activity, depression, weight loss, and Hydroxyl Radicals. In addition to
helping with existing conditions, molecular hydrogen is very good at prevention of conditions. It is
truly one of the best anti-aging tools you can use.
I. History of Hydrogen Enriched Water
Machines.

The history of water electrolysis began in the year 1800

when Anthony Carlisle, a surgeon in London, and William
Nicholson (pictured right) discovered water electrolysis by
passing a voltaic current through water, reducing it into its
constituent elements of hydrogen gas and oxygen gas
(2H2O--> 2H2 + O2). He wanted to create a hydrogen
generator because he had heard in 1798 that hydrogen had
anti-oxidant properties. In 1931, Dr. Machisue Suwa began
researching the effects of electrolyzed reduced water on plants and animals. In 1952 Dr. Suwa
developed the first machine that produced electrolyzed reduced water. He called the water
Synnohl Liquid. The water successfully improved rice cultivation. In 1960, the Synnohl Liquid
Medical Science Research Association was established. The first order of business was to
expand its research of electrolyzed water beyond agricultural uses into the medical field and
human use. In 1965, water ionizers that make electrolyzed reduced water or ionized water were
officially registered as medical devices with the Japanese Ministry of Health Labor and Welfare
because it had been proven to be effective against chronic diarrhea, indigestion, abnormal
stomach or intestinal fermentation & acid control. It wasnt understood that hydrogen was
responsible for the benefits until much later. Korea shortly
after followed suit.

II. Evolution of Water Electrolysis Machines

Early electrolysis devices produced only one batch of water

at a time. In 1979, flow through machines were introduced.
Flow through machines became popular because of the
convenience of having electrolyzed water on demand.
During the last 40 years, significant advancements have
been made. In 2007, Nature Medicine published a study
showing that molecular hydrogen was a selective anti-
oxidant targeting only oxidative radicals. In 2010, Paul
Barattiero, C.Ped, owner and founder of Synergy Science, Inc. developed the Echo brand of
electrolysis machines to produce the best hydrogen water available. The focus was to produce
the highest amount of H2, with very little maintenance. He developed the system to have robust
filtration, an attractive look, ease of use, installation included, a Forever warranty, low monthly
payments, and exceptional support and education. Understanding that most women want to
preserve their counter space, He developed the first convertible machine that could be used
above counter or below counter. An Echo digital faucet was developed to allow the machine to
be installed under sink and be controlled by the Echo digital faucet. You can add the digital
faucet at any time. (pictured pg. 4).

III. How Does Electrolysis Create Hydrogen?

Electrolysis of water has been used for

decades for the production of hydrogen gas.
It converts water (H2O) to hydrogen gas (H2)
and hydroxide ions (OH-) at the negative
side (cathode), and oxygen gas (O2) and
hydrogen ions (H+) at the positive side
(anode). Water electrolysis machines have a
membrane that separates the alkaline OH-
ions from the acidic H+ ions. The outlet from
one side of the membrane gives alkaline water, which contains dissolved hydrogen gas (H2), and
the other side of the membrane gives acidic water, containing dissolved oxygen gas (O2).

IV. Why is H2 Important?

The H2 molecule, unlike other antioxidants, is a selective antioxidant that

only targets the damaging free radicals like hydroxyl radicals (HO*),
converting them to water. It can also prevent oxidative stress by
increasing the bodys own antioxidants such as glutathione. It also has
beneficial cell signaling properties. The hydroxide (OH-) ions are
responsible for the alkaline pH, but they are not antioxidants themselves.

Finally in 2007, it was clearly shown that molecular hydrogen is what caused the benefits in the
water. H2 gas can act as a selective antioxidant and is responsible for the therapeutic properties
observed with alkaline or ionized water. No one had investigated hydrogen gas before: everyone
assumed it was just an inert byproduct of electrolysis - with no biological effect. If we remove
hydrogen gas from ionized water the therapeutic effects are lost. When we add additional
hydrogen gas to ionized water (e.g. via bubbling) the positive benefits, in many cases, are
increased.

V. Why Dont People Drink Enough Water?

A study conducted by the CDC showed that 54.5% of individuals age 6-19 in the USA are
chronically dehydrated. The definition of dehydration is when the body loses more fluid than it
takes in. Why dont people drink enough water? Many people dont like the taste of water are
worried about the pollutants in water. A study1, released in January 2014, was published in the
Journal of Environmental Pollution. The study was conducted by the Environmental Protection
Agency (EPA). It is the largest study of water coming out of wastewater treatment plants. The
study looked at samples from 50 large-size wastewater treatment plants nationwide and tested
for 56 drugs including oxycodone, high-blood pressure medications, and over-the-counter drugs
like Tylenol and ibuprofen. More than half the samples tested positive for at least 25 of the drugs
monitored. High blood pressure medications appeared in the highest concentrations and most
frequently.
Another study2 released in January 2014, showed that
there were 24,500 chemicals in bottled water that are
known to cause cancer, gynecological issues, 90%
reduction in estrogenic receptor activity, and 60%
androgenic receptor activity. Bottled water companies
market bottled water as healthier and cleaner. However, in
the processing of the bottles, the water is shown to harm
those who drink it, even in amounts as small as .1 oz. As
previously stated tap water can have impurities despite the
purification methods used. Echo water tastes better because of the multi stage filtration. It also
has health benefits due to the dissolved H2 gas

VI. The Echo Difference

The Echo Water machines are the most advanced and highest
performing available. The Echo water machine can be on your
counter or under your sink by adding the Echo Digital Faucet
(pictured right). The Echo Digital Faucet enables you to keep
your counter space and still control the machine below counter.
It is available in Satin, Oiled Bronze, and Chrome to compliment
any kitchen.
High concentration of molecular hydrogen.
Installation Included. (Incl. Hole drilled and electrical
outlet under sink if needed.) Over 120 installers in USA.
The Echo Forever Warranty covers parts, labor, and shippingForever.
Patented Anti-scale technology changes polarity of the electrodes every time the machine
is used. It is impossible for calcium or scale buildup on the electrodes.
It is critical to stop calcium from bonding to the cathode because molecular hydrogen will no
longer be dissolved. Other machines scale up in a matter of weeks and the benefits disappear.
Because Echo water machines dont allow calcium buildup inside the electrolysis chamber, you
can count on the H2 benefits forever. You can enjoy Echo water forever.

VII. Echo Filtration

Filtering water is critical in todays world. We often hear about the toxic substances in water.
Studies1,2 have found all kinds of toxins, drugs, metals, pesticides, etc. in drinking water. The
Echo water machine has a very effective filter. It removes the pollutants but, leaves the
minerals. The filter is designed to last up to 1000 gallons (roughly 1 year residential use). The
Echo Water Ionizer will tell you Please Change Filter when needed. 50%-60% of fluoride is
removed. If you want all of fluoride removed, we have a fluoride specific filter available.
Tourmaline in the Echo filter emits Far Infrared energy into the water to support detoxification.
With the light, fresh & clean taste you will enjoy drinking Echo water.

VIII. Benefits of Echo Water

Everyone is talking about how free radicals are damaging our cells. What most people dont know
is that many free radicals are beneficial to health. It is only the cell damaging (cytotoxic) radicals
that we need to scavenge. Molecular hydrogen converts these cytotoxic (hydroxyl (HO*) radicals)
into water molecules. An Echo Water machine converts municipal, well, or reverse osmosis
water into Hydrogen Enriched Water. Once the oxidative burden is reduces in the cells of the
body, the body can naturally produce glutathione.
Athletic Performance:

Echo Hydrogen Enriched Water has increased the performance of many athletes. Elite
athletes know that part of keeping their bodies in peak condition is understanding the science of
their bodies. Proper hydration is critical for performance. Echo Hydrogen-Enriched Water is
the best water for athletes. It better empowers cells to work at optimal efficiency by ridding them
of oxidative stress. Echo water is Hydrogen-Enriched which lessens lactate in muscles
significantly reducing fatigue. Athletes can perform significantly
better and longer. Another huge benefit is recovery times are
cut in half. When a person is properly hydrated with hydrogen-
enriched Echo water, they perform at peak levels longer.
Athletes who drink Echo water report that they experience
increased energy and performance. Many athletes indicate they
were able to get past their plateau because of Echo Water.

Detoxification & Weight Loss:

Water has been used in purification and cleansing from the

beginning of time. After all, water is the ultimate solvent. Water is used to remove toxins and
waste. Echo water supports healthy cleansing and weight loss. When the toxins and wastes
are flushed, the burden on the body is lessened. Echo Water can help to clean out the
intestines and colon. This greatly increases health and immunity. People report that they feel
more hydrated and lose weight with hydrogen-enriched Echo water, they experience more
productive sleep, wake up more alert, have fewer allergy symptoms, and feel more energy
throughout the day.

Immune System Boost:

No one enjoys getting sick because life comes to a screeching halt. The immune system and the
digestive system are directly linked to hydration. Being properly hydrated is one of the best steps
to increase your immune system and preventing sickness and disease. Remember, 60-75% of
your body is water and it should be no surprise that the type of water you drink can directly
influences the way you feel. Hydrogen enriched water is known for cleaning out intestines.
Intrinsic Energy and Frequencies:

Many people understand that energy and frequencies are all around us. Radio frequencies, cell
phone frequencies, Infrared energies, EMFs, etc. There are good and bad energies and
frequencies. The Echo system has hundreds of beneficial energies and frequencies. They can
protect you from harmful frequencies and energies. Those that are intuitive can feel them
immediately. Others say that the water just feels good to them. Those in energy medicine, Cranial
Sacral Therapists, Reiki Masters, etc. love Echo water.

Proper Hydration:

A study3 conducted by the University of Utah, showed the more water you drink the better. In the
study, subjects consumed either 4, 8 or 12 glasses of water daily. On the fifth day before rising,
their hydration status was monitored and a computer measured how many calories they had
burned in a resting state. The groups who drank 8 and 12 glasses of water daily were sufficiently
hydrated, whereas subjects who drank only four showed definite signs of dehydration.
Furthermore, the well-hydrated subjects not only reported better concentration and more energy,
but they burned more calories at rest than the group who drank only 4 glasses. These results
were in line with previous3 University of Utah findings that the ability to burn Calories can decline
by about 2% per day when people are dehydrated.

Increased Cognitive Function - Ghrelin:

Studies have shown that molecular hydrogen

stimulates Ghrelin secretions. Ghrelin is known as
the hunger hormone in the body. Ghrelin affects
many things in the body including cognitive
function, hunger, weight regulation, anti-
inflammatory function. This is accomplished in the
hippocampus, hypothalamus and the brain stem. Specific studies have shown that Hydrogen
Enriched Water can be tremendously beneficial to neurologic pathologies like Parkinsons,
Alzheimers, Bipolar, Schizophrenia, and Autism due to ghrelin secretion stimulation. Most of us
want to be smarter and benefit from improved cognitive abilities.

IX. Echo H2 DROPS:

Echo H2 Drops were designed for people to have hydrogen enriched water anywhere. It creates
molecular hydrogen in water when a specific type of magnesium that reacts in water to create
hydrogen gas. It is easy to use the Echo H2 Drops. The Echo H2 drops produce a therapeutic
concentration of molecular hydrogen and 25mg of Magnesium.
Study references:
1. https://echoh2water.com/studies
2. https://echoh2water.com/studies
3. http://healthcare.utah.edu/publicaffairs/news/archive/2003/news_74.php

X. Scientific Studies

There have been many studies completed in Japan, Korea, and the U.S.A. showing molecular
Hydrogen has therapeutic benefits. Please visit https://echoh2water.com/studies to read clinical
studies which are continually updated.
To learn more about molecular hydrogen visit www.molecularhydrogenfoundation.com .

Runtuwene et al. (2015), Hydrogenwater enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ 3:e859; DOI
10.7717/peerj.859. 2015 April 7

Hydrogenwater enhances 5-fluorouracil-induced inhibition of Colon Cancer

Joshua Runtuwene1,2, Haruka Amitani1, Marie Amitani1, Akihiro Asakawa1, Kai-Chun Cheng1 and Akio Inui1

1 Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and
Dental Sciences, Kagoshima, Japan 2 Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
ABSTRACT

Oxidative stress is involved in cancer development. Hydrogen (H2) is a potent antioxidant and exhibits anti-
inflammatory and potentially anticancer-like activities. This study aimed to investigate the role of H2 in
combination with 5-fluorouracil (5-FU) in cancer treatment both in vitro and in vivo using the colon 26 cell
line. The survival rate was determined using the KaplanMeier survival test, and cell viability was assessed
using cell viability imaging kit and the MTT assay, and activation of the cell apoptosis pathway
(Phosphorylated adenosine monophosphate activated protein kinase (p-AMPK), Apoptosis-inducing factor
(AIF) and Caspase 3) were characterized by western blots. Hydrogen water administration improved the
survival of mice with colon 26-induced cancer. Furthermore, hydrogen water enhanced cell apoptosis in
cancer cells, resulting in a marked increase in the expression of p-AMPK, AIF and Caspase 3 in colon 26
cells. Hydrogen water also increased the inhibitory effect of 5-FU on colon 26 cells with respect to cell
survival rate and anticancer functions. Additionally, high-content hydrogen water exhibited stronger ant
oxidative and anticancer activity than did the natural hydrogen water. In conclusion, high-content hydrogen
water can inhibit colon cancer, particularly in combination with 5-fluorouracil.
Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by
electrolyzed reducing water.
Department of Physiology of Microorganisms, Biology Faculty, Lomonosov Moscow State University,
119992 Moscow, Russia. nvvorobjeva@mail.ru

96-99% of the "friendly" or residential microflora of intestinal tract of humans consists of strict anaerobes and only 1-4%
of aerobes. Many diseases of the intestine are due to a disturbance in the balance of the microorganisms inhabiting the
gut. The treatment of such diseases involves the restoration of the quantity and/or balance of residential microflora in
the intestinal tract. It is known that aerobes and anaerobes grow at different oxidation-reduction potentials (ORP). The
former require positive E(h) values up to +400 mV. Anaerobes do not grow unless the E(h) value is negative between -
300 and -400 mV. In this work, it is suggested that prerequisite for the recovery and maintenance of obligatory
anaerobic microflora in the intestinal tract is a negative ORP value of the intestinal milieu. Electrolyzed reducing water
with E(h) values between 0 and -300 mV produced in electrolysis devices possesses this property. Drinking such water
favors the growth of residential microflora in the gut. A sufficient array of data confirms this idea. However, most
researchers explain the mechanism of its action by an antioxidant properties destined to detox the oxidants in the gut
and other host tissues. Evidence is presented in favor of the hypothesis that the primary target for electrolyzed
reducing water is the residential microflora in the gut.
PMID: 15617863 [PubMed - indexed for MEDLINE]

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute
exercise in elite athletes

Kosuke Aoki1, Atsunori Nakao2*, Takako Adachi1, Yasushi Matsui1 and Shumpei Miyakawa1

Abstract
Background: Muscle contraction during short intervals of intense exercise causes oxidative stress, which can
play a role in the development of overtraining symptoms, including increased fatigue, resulting in muscle
microinjury or inflammation. Recently it has been said that hydrogen can function as antioxidant, so we
investigated the effect of hydrogen-rich water (HW) on oxidative stress and muscle fatigue in response to acute
exercise. Methods: Ten male soccer players aged 20.9 1.3 years old were subjected to exercise tests and blood
sampling. Each subject was examined twice in a crossover double-blind manner; they were given either HW or
placebo water (PW) for one week intervals. Subjects were requested to use a cycle ergometer at a 75 %
maximal oxygen uptake (VO2) for 30 min, followed by measurement of peak torque and muscle activity
throughout 100 repetitions of maximal isokinetic knee extension. Oxidative stress markers and creatine kinase
in the peripheral blood were sequentially measured.

Results: Although acute exercise resulted in an increase in blood lactate levels in the subjects given PW, oral
intake of HW prevented an elevation of blood lactate during heavy exercise. Peak torque of PW significantly
decreased during maximal isokinetic knee extension, suggesting muscle fatigue, but peak torque of HW didnt
decrease at early phase. There was no significant change in blood oxidative injury markers (d-ROMs and BAP)
or creatine kinease after exercise.
Conclusion: Adequate hydration with hydrogen-rich water pre-exercise reduced blood lactate levels and
improved exercise-induced decline of muscle function. Although further studies to elucidate the exact
mechanisms and the benefits are needed to be confirmed in larger series of studies, these preliminary results
may suggest that HW may be suitable hydration for athletes.

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