Professional Documents
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ly
pretation, writing the article, critical revision of
clinical interest. Inpatients of a general psychi- faction correlated negatively with depression
the article, final approval of article; MTH, concep-
on
atric care hospital were asked to fill out ques- scores and personality pathology, whereas tion and design of the research project, collection
tionnaires on satisfaction at discharge and length of stay, age and sex contributed mini- and assembly of data, data analysis and interpre-
clinical variables at admission and mally.4 In another study patient satisfaction tation, critical revision of the article, final
discharge were assessed. On the basis correlated negatively with severity of depres-
e
approval of article.
of an exploratory approach, differences in sive symptoms at discharge and number of
treatment satisfaction among diagnostic
groups were examined by means of one-way
us
comorbidities in major depressive disorder.5
A meta-analysis suggested that patients
Conflict of interest: the authors declare no con-
flict of interest.
with psychiatric disorders preferred a psycho-
al
analysis of variance. Potential associated clin-
logical treatment opposed to a psychopharma- Received for publication: 5 September 2016.
ical and socio-demographic variables were Revision received: 1 November 2016.
ci
significantly lower treatment satisfaction study pharmacotherapy itself was not related This work is licensed under a Creative Commons
(ZUF-8, Zurich Satisfaction Questionnaire) to patient satisfaction, but patients who per- Attribution-NonCommercial 4.0 International
m
and a slightly lower improvement of symptoms ceived improvements in pharmacotherapy as License (CC BY-NC 4.0).
(CGI, Clinical Global Impression) and global one of the most important treatment outcomes
om
were less satisfied than others.2 Additionally, Copyright S. Gebhardt and M.T. Huber, 2016
functioning (GAF, Global Assessment of Licensee PAGEPress, Italy
Functioning scale) than that of other diagnos- we could describe an association of a reduced
Mental Illness 2016; 8:6868
tic groups (n=95). Satisfaction in patients treatment satisfaction with pharmacological
-c
doi:10.4081/mi.2016.6868
with personality disorders correlated much problems.3 It could be shown that the number
of prescribed drugs correlated negatively with
on
Interestingly, in patients with personality dis- Furthermore, the psychiatric diagnosis tion; however, patients with depressive disor-
orders psychopharmacological treatment in seems to be relevant with respect to patient der and comorbid personality disorder showed
general (present versus not present) was inde- satisfaction. In an outpatient study patients a lower satisfaction than depressive patients
pendent from satisfaction. This exploratory with somatoform, eating, and personality dis- without a personality disorder.5 In a previous
investigation suggests that a lower satisfac- orders were shown to be less satisfied than study it could be shown that global subjective
tion of patients with personality disorders in a patients with affective, anxiety, and adjust- quality of life was lower in patients with per-
general psychiatric hospital is mainly based on ment disorders.2 Other studies suggest a sonality disorders compared to patients with
a reduced improvement of the symptoms and reduced satisfaction in patients with sub- major mental (psychotic) disorders.10
of the global functioning level. stance abuse compared to patients with a
The variables age, sex and education seem
major depressive episode.7 In a post-hoc analy-
to have no relevant influence on satisfaction,
sis of six studies of patients with major depres-
whereas race in case of minority groups,
sive disorder the change in satisfaction with
Introduction antidepressant drugs from baseline to end-
patients in mental health care, psychiatric
diagnosis, chronicity of illness, poor prognosis,
point was significantly correlated with sympto-
Patient satisfaction with treatment is more matic improvement on the depressive symp- compulsorily detained patients obviously show
and more recognized as one of the worthiest toms,8 a comparable result was found in anoth- lower satisfaction levels.11
parameters of treatment success and has a er study.5 Similarly, in patients with schizo- However, the current state of research is
strong impact on institutional quality manage- phrenia depression score is correlating nega- still scarce. In the present investigation subse-
ment. Departments of psychiatry are still in tively with the subjective well-being score.9 A quent to our main hypothesis-testing
the beginning of developing standards to recent study showed no differences between approach,3 we now used an exploratory
approach to focus on these three dimensions Declaration of Helsinki and its later amend- patient), CGI at admission and at discharge
(symptom severity, psychopharmacology, diag- ments (approved at 3rd November 2008 by the (CGI part 1), CGI change (CGI part 2), GAF at
nosis) with respect to satisfaction and in rela- rztekammer Niedersachsen Hannover; State admission and at discharge, GAF difference
tionship to each other. We followed this proce- Medical Chamber of Lower Saxony, Germany). between admission and discharge, an addic-
dure: firstly, to explore differences in treat- The average duration since psychiatric diag- tion disorder as main or comorbid disorder,
ment satisfaction among specific diagnostic nosis was 5.17.9 years. Mean inpatient treat- single items of the ZUF-8.
groups; secondly, to identify significant differ- ment duration was 1.41.2 months. Thirty- Differences between patient groups were
ences in treatment and socio-demographic three patients (29.2%) received antidepres- studied using multi/univariate variance analy-
variables of the patients groups who are differ- sants, 25 (22.1%) antipsychotics, and 34 ses (Pillais trace) and Students t-tests for
ing in treatment satisfaction. (30.1%) both in combination; 13 patients continuous variables and chi-square test for
(11.5%) received no medication. dichotomous data. Furthermore, the Mann-
Psychotherapy was predominantly or concomi- Whitney-U-test was used in case of ordinal
tantly used in those mental disorders which dependent variables or non-normally distrib-
Materials and Methods profit from psychotherapy according to the cur- uted variables identified by the Kolmogorov-
rent state of research, e.g. neurotic disorders Smirnov-test.
Sample description or personality disorders. The psychotherapy Finally, variables were identified which cor-
was mainly based on cognitive behavioral ther- relate with patient satisfaction (Pearson corre-
113 inpatients (52.8 %; 59 females, 54 apy with psychodynamic elements. lation) or are associated (in nominal variables,
males; mean age at discharge 48.316.6 years; t-tests) within the group of personality disor-
range 18.5-87.3 years; mean inpatient treat- Instruments ders. A multivariate analysis was used to iden-
ment duration 1.41.2 months) admitted to The ZUF-8 (Zurich Satisfaction tify the main impact of these dependent vari-
Questionnaire; a questionnaire of patient sat-
ly
the Department of Psychiatry, Psychotherapy ables on the differences between the two
and Psychosomatics, Stade City Hospital, isfaction)13 was applied at discharge. It repre- patient groups.
on
Germany, between May and August 2009 were sents a reliable and valid self-evaluation ques- Additionally, to elucidate the improvement
investigated. The psychiatric hospital at the tionnaire of patient satisfaction with the treat- in both patient groups, a longitudinal analysis
Elbe Klinikum Stade is an academic teaching ment. In our study sample reliability analysis on CGI part 1 at admission to discharge was
e
hospital containing three general psychiatric revealed a good internal consistency conducted for each group separately (Students
(Cronbachs alpha 0.886). For the evaluation of
inpatient wards for 80 patients, a day clinic
with 23 places and an outpatient department.
The hospital is responsible for the complete chosocial functioning
us
general treatment variables as well as the psy-
the BADO
t-test for dependent samples).
All P-values were two-tailed; 0.05 was the
significance level. A correction for multiple
(Basisdokumentation; basic documentation)14
al
inpatient psychiatric care of the county of testing was not included because of the
questionnaire was used including self-rated
Stade with approximately 200.000 inhabitants. exploratory nature of our study. The data were
ci
Of the 113 patients 4 patients were treated the diagnostic groups were examined using In the first calculation significant differ-
involuntarily. 7 patients had a private health Oneway ANOVA analysis with post-hoc-tests ences in ZUF-8 total score between the diag-
on
insurance. (Scheff). The diagnostic groups F5 and F7 nostic groups were detected (P<0.001). In the
The patients were diagnosed according to were excluded from the analysis because the post-hoc-tests, personality disorders proved to
the International Classification of Diseases be different from each other diagnostic group
N
during the treatment (CGI part 2 and the The examination of associated variables but not with other variables including GAF at
GAF change): Patients with personality dis- revealed the following results. Patients with discharge or delta GAF.
orders showed a significantly lower personality disorders were significant younger Patients with personality disorders and
improvement of symptoms during the treat- than patients with no personality disorders those without did not differ in the variables:
ment (CGI part 2: 3.5 vs. 3.1; Mann-Whitney- (40.113.2 vs. 49.916.7 years; t-test: gender, school examination level, duration of
U-test: P=0.019; and GAF change: P=0.022). Furthermore, in patients with per- the mental disorder (anamnestic data), num-
+18.314.7 vs. +25.814.5; Mann-Whitney- sonality disorders the duration of the current ber of hospitalizations, general psychopharma-
U-test: P=0.026). Obviously, patients with symptom manifestation was longer (in the cological treatment (versus none), pharmaco-
personality disorders have been rated slight- mean higher than 6 months) (Mann-Whitney- logical problems, CGI part 1 and GAF at admis-
ly worse in the improvement of psychiatric U-test: P=0.011) and the inpatient treatment sion, an addiction disorder as main or comor-
symptoms and general functioning during duration slightly longer (2.01.4 vs. 1.31.2 bid disorder (n=37), single Zuf-8 items.
the psychiatric treatment compared to the months; t-test: P=0.056, trend) compared to Among the patients with personality disor-
patients without personality disorders. the remaining patients. Further, patients with ders, patient satisfaction correlated strongly
II) With respect to the endpoint status at dis- personality disorders showed a trend towards a negatively with a symptom worsening (CGI
charge (CGI part 1 and GAF): However, at lower number of somatic diagnoses (0.70.8 part 2; r=-0.768; P<0.001), whereas in patients
the time of discharge, no significant differ- vs. 1.11.5; t-test: P=0.070) and a better occu- without personality disorders the correlation
ence in the symptom severity/level of global pational level as well as a better job situation was much weaker and only a trend (CGI part 2;
functioning could be revealed: the CGI part (Mann-Whitney-U-Test; P=0.007/P=0.085) r=-0.185; P=0.072; Figure 1). Furthermore,
1/GAF score at discharge was compared to patients without personality dis- among the patients with personality disorders,
4.51.2/64.411.6 in personality disorders orders. Finally, the use of antidepressants was patient satisfaction correlated as a trend posi-
and 4.21.2/67.011.6 in other diagnoses slightly more frequent in patients with person- tively with the improvement of the functioning
ly
(Mann-Whitney-U-tests). The longitudinal ality disorders (14 patients vs. 4) compared to level (delta GAF; r=0.435; P=0.071), whereas
analysis within the patient group of person- the other patients (53 vs. 42) (Mann-Whitney- no significant correlation could be revealed in
on
ality disorders, or the non-personality group, U-test; trend: P=0.083). patients without personality disorders.
respectively, also revealed a good symptom Correlations with patient satisfaction of the Additionally, the use of antidepressants was
improvement (CGI part 1) in both the per- variables which were associated with the diag- positively associated with an increased patient
e
sonality disorder group (CGI part 1 at admis- nosis of a personality disorder were also evalu- satisfaction as a trend (P=0.092; t-test) in
sion 6.00.6; at discharge 4.51.2; P<0.001)
and the non-personality disorder group (CGI
part 1 at admission 6.20.8; at discharge
us
ated in the group of other diagnoses. Hereby
we found only a positive correlation of patient
satisfaction with the job situation (r=0.233;
patients with personality disorders, but not in
those without the diagnoses of a personality
disorder.
al
4.21.2; P<0.001) (Students t-test for P=0.025) and as a trend with the symptom Finally, in the multivariate analysis on the
dependent samples). improvement (CGI part 2; r=-0.185; P=0.072), total sample we checked the impact of these
ci
er
Table 1. Mean values of the tested variables and their statistical differences between patients with personality disorders and those with-
m
out.
Variables Personality disorders Other diagnoses Statistical
om
three variables (see above; CGI part 2, delta chotics, mood stabilizers,18 and dietary supple- The role of symptomatology and
GAF, use of antidepressants) which correlated mentation by omega-3 fatty acids in borderline psychosocial functioning
or were directly associated with patient satis- personality disorder, but no significant influ-
Within the group of personality disorders
faction within the personality disorder group. ence of any drug on total severity and core fea-
patients clearly improved during the treatment
Pillai trace was P<0.001, with the dependent tures of borderline personality disorder. Two
in symptomatology and global functioning (t-
variables CGI part 2 (P=0.042), delta GAF studies showed a significant impact on quality
test for dependent samples). At the time of dis-
(P=0.048) and use of antidepressants of life in case of risperidone and topira-
charge both the patients with and those with-
(P=0.059; trend). mate.19,20
out personality disorders showed a sufficient,
The personality disorder patient group
not significantly differing global functioning
showed a younger age, a longer symptom dura-
level. The multivariate analysis revealed a
tion of the current symptom manifestation, a
major influence of the improvement of sympto-
Discussion lower improvement of symptoms and function-
matology and of the global functioning as well
ing level during the inpatient treatment,
of the use of antidepressants on the patient
General findings despite of a longer treatment duration and the
satisfaction. Thus, the reduced treatment sat-
This present exploratory investigation was higher use of antidepressants, less somatic
isfaction in patients with personality disorders
conducted in a general psychiatric clinic diagnoses as well as a better occupational level
seems to be due to less improvement of symp-
(Stade/Germany) providing the health service and a slightly better job situation. However,
tomatology and of global functioning during
for a specific geographic region. We found an within the patients with personality disorders,
the treatment (and despite of an increased use
overall very good patient satisfaction with the satisfaction correlated only with the improve-
of antidepressants); these both variables
inpatient treatment. Both patient groups, ment of the symptoms and of the global func-
seem to have the highest impact, and possibly
those with and without personality disorders tioning level.
the role of diagnoses as proposed in previous
In contrast, patients with personality disor-
ly
showed a significant improvement of their studies.2 Interestingly, treatment satisfaction
symptoms, however in patients with personali- ders and those without did not differ in the fol-
was much stronger correlated with symptom
on
ty disorders a slightly lower improvement. lowing variables: gender, school examination
improvement during the therapy in patients
Accordingly, the treatment satisfaction was level, duration of the mental disorder, number
with personality disorders than in patients
slightly, but significantly reduced in patients of hospitalizations, general psychopharmaco-
without personality disorders (Figure 1).
e
suffering from personality disorders in com- logical treatment (versus none), pharmacolog-
Obviously patients with personality disor-
parison to the remaining patients.
Influences of treatment and socio-
us
ical problems, symptom severity at admission,
addiction disorders. Thus, these variables can-
not be considered responsible for the differ-
ders seem to focus especially on the changes of
their symptoms during the treatment in order
to estimate their satisfaction. It can be sug-
al
demographic variables ence of treatment satisfaction.
To further explore the reduced satisfaction
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gested that dysfunctional assumptions which might be the result of an epiphenomenon of therapy of fluoxetine with interpersonal psy-
are characteristic in personality disorders sub-population suffering mostly from an affec- chotherapy adapted for borderline personality
might lead to false expectations concerning tive disorder, because affective disorders (and disorder proofed to be related to more quality
the treatment success. Additionally, the fact also reactive psychoses) have been identified of life as a long-term effect versus single fluox-
that patients with personality disorders have to be associated with more treatment satisfac- etine administration.28 In case of schema ther-
strong difficulties in personal relationships tion than the diagnoses schizophrenia, para- apy a high treatment satisfaction was demon-
often affects the therapeutic relationship and noia as well as transitory adjustment reac- strated in 31 patients with severe borderline
can thereby influence the patient satisfaction tions.21 We also reported previously of a personality disorder.29
negatively. A general life dissatisfaction, and reduced satisfaction in both personality disor- According to a recent review the quality of
therefore also treatment satisfaction, in per- ders and schizophrenia.3 However, the link of live is seriously impaired in borderline person-
sonality disorders might represent a core fea- the diagnosis schizophrenia with a reduced ality disorder patients.30 It has to be mentioned
ture of the disorder. Investigating the extent to treatment satisfaction might be a false positive that the quality of life concept has similarities
which subjective dissatisfaction is intrinsic to finding of the hypothesis-testing approach to the concept of treatment satisfaction, if
personality disorders, Bouman et al.10 found (investigating the group of both personality quality of life is measured at the end of a ther-
the global subjective quality of life to be lower disorders and schizophrenia together), apy; as well, the level of functioning is a deter-
than in patients with (other) major mental dis- because it was not mirrored by the current minant of the quality of life. Psychotherapy tri-
orders, whereas the objective quality of life exploratory approach. In some other former als with available empirical data on quality of
was mostly significantly poorer among men studies no difference between psychotic and life (dialectic behavioral therapy, cognitive-
with major mental disorders than those with non-psychotic groups in treatment satisfaction behavioral therapy, schema-focused therapy,
personality disorders. A more complex concept could be found, as well.26,27 transference-focused psychotherapy, systems
of quality of life in patients with personality In 1996 Hueston et al. published a study in training for emotional predictability and prob-
ly
disorders was supposed compared to patients 93 patients of a primary care sample.22 The lem solving) show a significant improvement
with major mental disorders for whom almost authors found lower levels of satisfaction with of quality of life, but only the psychotherapy
on
half of the variance in subjective quality of life health care in patients who were at high risk forms dialectic behavioral therapy31 and sys-
rating was related to their everyday activities (n=65) for personality disorders compared to tems training for emotional predictability and
and their objective sense of safety.10 those at low risk (n=28). These authors found problem solving32 have been shown to be supe-
e
only a little association between personality rior to treatment as usual; for cognitive behav-
Reference to previous studies
The reduced satisfaction in personality dis-
orders is a phenomenon which could already
us
disorder type and level of satisfaction. Except
for patients with dependent personality ten-
dencies all other personality dimensions
ioral therapy there was no difference.33,34
Furthermore, an inpatient treatment is limited
by the conditions of the current form of most
al
be shown in previous studies,2,21-24 though its showed lower degrees of satisfaction. acute general psychiatric hospitals (e.g., the
reasons are not understood. Especially the Furthermore, especially patients at high risk comparably short treatment duration) which
ci
Cluster B personality traits (e.g., antisocial and for borderline, schizoid and dependent disor- are still not designed to provide a comprehen-
borderline personality disorder) but also
er
ders showed a lower functional status, a high- sive sufficient psychotherapy. Especially for
Cluster A as a paranoid personality profile er risk for depression or alcohol abuse in that the treatment of personality disorders a per-
seem to be linked with a decreased treatment
m
treatment,11,22,25 whereas dependent personal- dependent disorders. Patients of that study an intensive therapeutic relationship and a
ity disorders seem to be less associated with a screening positive for narcissistic, schizotypal, differentiated macroanalytic diagnostic is nec-
low treatment satisfaction.21 A study of Miller antisocial, and obsessive-compulsive disorders essary in order to initiate therapeutic process-
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et al.25 in 543 psychiatric patients (mostly were noted to have the least functional impair- es, in particular the transformation of emo-
inpatients) suggests that both maladaptive ment, depression, and health care utiliza- tional key experiences.35 In patients with mood
on
personality symptoms and general personality tion.22 These differences could not be instability such as borderline personality disor-
traits are predictive of psychiatric treatment explained by demographic or socioeconomic ders, a patient-centered communication,
utilization and satisfaction. The personality
N
differences. Patients at high risk for personal- which acknowledges the patients experience,
trait openness has been found to be correlated ity disorders were more likely to be taking an may result in a greater patient satisfaction
positively with treatment satisfaction.25 In that antidepressant drug.22 according to a qualitative study.36 And treat-
study also a relationship of dissatisfaction with ment satisfaction might appear parallel to
ones medication and the diagnosis of a bor- Therapeutic setting dimensions such as personal growth, purpose
derline personality disorder could be detected. General psychiatric hospitals are obliged to of life, and changes in positive relations with
Our investigation can be compared to a sur- admit patients with very severe psychiatric dis- others.37
vey of treatment satisfaction of 142 psychiatric orders, mostly those who have been rejected
inpatients in 1993.21 This study of Kelstrup et from specialized psychotherapy clinics for sev- Limitations
al. revealed that patients without a personality eral times because they have not fulfilled their The study has some limitations. Due to the
disorder were more satisfied than patients admission criteria (such as therapy motiva- exploratory nature of the study we refrained
with antisocial or borderline personality disor- tion). Therefore, one reason for the reduced from multiple testing. Accordingly, the results
ders. Patients who received antidepressant treatment satisfaction in patients with person- have to be rated carefully. Some diagnostic
medication were much more satisfied with the ality disorders might lie in a lack of a special- subgroups are very small to consider a valid
treatment than patients without antidepres- ized (e.g., psycho-) therapy track, such as in differentiation in terms of treatment satisfac-
sants, whereas there were no significant dif- case of emotional unstable personality disor- tion. Furthermore, nosological aspects as well
ferences in patients on antipsychotics, benzo- ders dialectic behavioral therapy, schema as differences in the course of the disease
diazepines nor individual psychotherapy (ver- therapy, mentalization-based therapy, transfer- between patients with personality disorders
sus none, respectively).21 The higher satisfac- ence-focused psychotherapy or acceptance and and other psychiatric diagnoses have to be
tion in patients under antidepressant drugs commitment therapy. For example, a combined considered. For example, personality disorders
often appear through the manifestation of 3. Gebhardt S, Wolak A, Huber MT. Patient 1995;24:3-41.
another (main) psychiatric diagnosis, such as satisfaction and clinical parameters in 15. Guy W. ECDEU Assessment Manual for
a depressive syndrome, so that it is difficult to psychiatric inpatients the prevailing role Psychopharmacology. Rockville, MD: US
talk of symptom manifestation of the personal- of symptom severity and pharmacological Dept. of Health, Education and Welfare,
ity disorder. Nevertheless, the comparably het- disturbances. Compr Psychiatry ADAMHA, MIMH Psychopharmacology
erogeneous sample allows the examination of 2013;54:53-60. Research Branch, 1976:218-22.
real world conditions of a typical general psy- 4. Horn K, Martinsen EW. Patient satisfac- 16. Sa H, Wittchen HU, Zaudig M, Houben I.
chiatric inpatient population. tion after hospitalisation in a psychiatric Diagnostic criteria of the Diagnostic and
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2007;127:1506-9. ed., revised (DSM-IV-TR). Gttingen:
5. Khler S, Unger T, Hoffmann S, et al. Hogrefe; 2003. pp 47-49.
Conclusions Patient satisfaction with inpatient psychi- 17. Saunders EF, Silk KR. Personality trait
atric treatment and its relation to treat- dimensions and the pharmacological treat-
In sum, the reduced satisfaction in patients ment outcome in unipolar depression and ment of borderline personality disorder. J
with personality disorders treated in a general schizophrenia. Int J Psychiatry Clin Pract Clin Psychopharmacol 2009;29:461-7.
psychiatric hospital seems to be mostly associ- 2015;19:119-23. 18. Stoffers J, Vllm BA, Rcker G, et al.
ated with a reduced improvement of global 6. McHugh RK, Whitton SW, Peckham AD, et Pharmacological interventions for border-
functioning and symptoms. It could be found, al. Patient preference for psychological vs line personality disorder. Cochrane
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patients with personality disorders compared Psychiatry 2013;74:595-602. Risperidone treatment of borderline per-
ly
to patients without, so that symptom improve- 7. Swoboda E, Khnel B, Wanders R, Knig P. sonality disorder assessed by a borderline
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on
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e
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group of patients with personality disorders
seems to represent a dimension which is
us
correlated with outcome but not persist-
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italopram, or serotonin-norepinephrine
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m
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om
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