OXIDOREDUCTASES CONH 2 COO 2.7.1.

15 Ribokinase
1.1.1.1 Alcohol dehydrogenase
HYALURONIC ACID DERMATAN BLOOD GROUP ALGINATES O-ANTIGENS STARCH GLYCOGEN + O O COO 2.7.1.16 Ribulokinase
1.1.1.3 Homoserine dehydrogenase P GLYCOPROTEINS SUBSTANCES CH2COO OH
+
N
O O
Ribose -O - P - O - P - O- Adenosine(P)
N
Ribose - O - P - O - P - O -Adenosine + NICOTINATE COO COO 2.7.1.17 Xylulokinase
1.1.1.8 Glycerol-3-phosphate dehydrogenase
O GANGLIOSIDES PEPTIDO- CH2OH CH2OH N
.11
+ COO
2.7.1.19 Phosphoribulokinase

GLYCAN CH OHCHITIN CHONDROITIN PECTIN INULIN CELLULOSE 2.4.2

1.1.1.9 D-Xylulose reductase NH O O N RP 2.7.1.24 Dephospho-CoA kinase
Ribose- P N
MUCINS O O
Indoleacetate
NH O O
6.3.5.1
L 2.7.7.18 2.7.1.25 Adenylylsulfate kinase
1.1.1.10 l-Xylulose reductase
2
O
HO Indoxyl NAD(P) +
Desamino-NAD Nicotinate- Quinolinate- A 2.7.1.28 Triokinase
1.1.1.14 l-Iditol dehydrogenase O O (Auxin) 6.3.1.5 2.4.2.19
1.1.1.19
1.1.1.21
Glucuronate reductase
Aldehyde reductase
Y AcNH
CHOH
O
COO - 6.3.2.7-10
O
COO - 2.4.1.68
2.4.1.69
1.1.1.132 HO CH3
OH OH OH
1.2.3.7
nucleotide nucleotide
2.4.2.19 R
2.7.1.30
2.7.1.31
Glycerol kinase
Glycerate kinase
S
CHOH O
1.1.1.22 UDPglucose dehydrogenase CH2OH
OPC
2.4.99.7 6.3.2.13 HO O OPPU
2.4.1.17
HO OH OPPU CH3
OPPT
2.4.1.29
OH
LACTOSE
OH
HO
+
CH2CH(NH3)COO HO CH 2CH2NH 2 HO CH2CH2NHCOCH 3 CH3O CH 2CH2NHCOCH 3 COO O 2.7.1.32
2.7.1.33
Choline kinase
Pantothenate kinase
A
1.1.1.23 Histidinol dehydrogenase CH3CH OH OH CH2CHO
1.1.1.25 Shikimate dehydrogenase
NHAC
UDP-
OH
HO HO OPPG
GDP- TDP-Rhamnose CH2OH NH NH NH NH N
COO
M 2.7.1.34 Pantetheine kinase
1.1.1.27 Lactate dehydrogenase
C HO
UDP-N-Ac-Muramate
COO-
Iduronate OH
2.4.1.21
2.4.1.1 2.4.1.11 HO
O
Indole-
NH
Indole
NH
5-Hydroxy- 4.1.1.28
5-Hydroxytryptamine 2.3.1.5 N-Acetyl-serotonin 2.1.1.4
N-Acetyl-5-O-methyl-serotonin Quinolinate A
2.7.1.36
2.7.1.39
Mevalonate kinase
Homoserine kinase
1.1.1.29 Glycerate dehydrogenase
Mannuronate CH3 etc. 3.2.1.23
tryptophan (SEROTONIN) (MELATONIN)
1.1.1.30
1.1.1.31
3-Hydroxybutyrate dehydrogenase
3-Hydroxyisobutyrate dehydrogenase
C CMP-N-Acetyl GDP-Fucose O 2.4.1.21
OH OH 2.7.1.38 acetaldehyde 1.14.16.4 T
2.7.1.40
2.7 1.47
Pyruvate kinase
D-Ribulokinase
1.1.1.32
1.1.1.34
Mevaldate reductase
Hydroxymethylglutaryl-CoA reductase (NADPH)
H neuraminate
HO
CH2OH
O COO 5.1.3.12
CH2OH
O
5.1.3.13 O
OH OPPT OH 4.1.1.43 +
+
COO I 2.7.1.53
2.7.1.60
l-Xylulokinase
N-Acylmannosamine kinase
1.1.1.35 3-Hydroxyacyl-CoA dehydrogenase A CHOH
CHOH
O
COO
2.4.1.16
COO -
4.2.1.47 2.4.1.33
OH ADP- CH2OH GALACTOSE
CH 2COCOO
CO CH2CH(NH 3)COO
CHO
+
CO CH2CH(NH 3)COO
COCH2CH(NH 3)COO
NH2
COO
NH2 OCH OCH NH2
C 2.7.1.71
2.7.1.80
Shikimate kinase
Pyrophosphateserine phosphotransferase
R AcNH NH2
1.1.1.37 Malate dehydrogenase
1.1.1.39 Malate dehydrogenase (decarboxylating) CH2OH OH OPPU O
HO OH HO OPPG CH2OH
O
TDP-4-Oxo- Glucose
O
CH2OH 4.1.99.1 NH
3.5.1.9
NH2 OH OH COO COO 2.7.1.82 Ethanolamine kinase
Kynurenine 1.14.13.9 3-Hydroxy 3-Hydroxy 1.13.11.6 2-Amino-3-carboxy 4.1.1.45
OH 3.7.1.3
HO 6-deoxyglucose NH
Formylkynurenine 2-Aminomuconate-
1.1.1.41
1.1.1.44
Isocitrate dehydrogenase (NAD+)
Phosphogluconate dehydrogenase I OH 2.7.7.43
3.1.3.29
1.1.1.158 CH2OH
O
NHCOCH 3 GDP-Mannose HO OH OPPU
2.7.1.6
HO
O
Indolepyruvate kynurenine anthranilate muconate semialdehyde 6-semialdehyde A
2.7.1.107
2.7.2.3
Diacylglycerol kinase
Phosphoglycerate kinase
(decarboxylating)
D HO UDP-N-Ac-
OH OPPU
CH2OH
HO OH HO OH
GDP-Glucose HO OP 1.13.11.11 COO H H Catechol M
2.7.2.4
2.7.2.6
Aspartate kinase
Formate kinase
1.1.1.45 l-Gulonate dehydrogenase
N-Ac-Neuraminate Galactosamine OH
UDP-Glucose
OH 2.4.1.22
E I

1.
1.1.1.49 Glucose-6-phosphate dehydrogenase HO O OPPU UDP-
O
MANNOSE + COO 2.7.2.11 Glutamate 5-kinase

4.
(Sialate) 2.7.7.13 4.2.1.46 OH CH2CH(NH 3)COO C-CH(OH)CH(OH)CH 2OP NH C C CH CH2OP 1.2.1.32
Galactose-P

1.
CH2 C CH2CH 2NH2 HOC-CH(OH)CH(OH)CH 2OP 2.7.3.2 Creatine kinase
1.1.1.56 Ribitol dehydrogenase COO 2
S Galacturonate 1.1.1.2
COO
N

19
CH2OP NHAC CH
1.1.1.79 Glyoxylate reductase (NADP+)
COO O 2.7.1.7 2.7.7.27 NH CH OH OH 1.14.12.1 2.7.4.2 Phosphomevalonate kinase
1.1.1.81 Hydroxypyruvate reductase O HO OH HO O P CH 2OH NH 4.2.1.20 N N O NH2 2.7.4.3 Adenylate kinase
H H NH 2
1.1.1.82 Malate dehydrogenase (NADP+)
ACNH
UDP-N-Ac-
3.1.3.29 5.1.3.7 Mannose-1-P
TDP-Glucose
2.7.7.34 2.7.7.9 5.1.3.2 HO
O
Tryptamine
4.1.1.28
TRYPTOPHAN Indole-3-glycerol-P 1-(o-Carboxy phenylamino)
4.1.1.48
N-(5-P-Ribosyl)
2.4.2.18
Anthranilate
OOC
OOC
2-Amino
O 2.7.4.4 Nucleoside-phosphate kinase
1.1.1.85 3-Isopropylmalate dehydrogenase
HO OH Glucosamine
OH
4.1.3.20 HO OH OPPU 5.1.3.6 CH 2OP
O 2.7.7.10 COO 1-deoxyribulose-5-P anthranilate
2.7.4.6 Nucleoside-diphosphate kinase
1.1.1.86 Ketol-acid reductoisomerase
pyruvate OH 2.7.7.12 OH OPPU OC muconate 2.7.4.8 Guanylate kinase
HO COO
A
1.1.1.95 Phosphoglycerate dehydrogenase COO COO OOC 2.7.4.9 dtmp kinase
1.1.1.100 3-Oxoacyl-[acyl-carrier-protein] reductase N-Ac-Mannosamine-6-P UDP-Glucuronate 5.4.2.8 2.7.7.24 CH 2OH
O OH P OCH 2 CH2 COO COO
COO
4.1.3.27
CH 2COCOO
2.7.4.14 Cytidylate kinase
HO OH HO OH
1.1.1.102 3-Dehydrosphinganine reductase
1.1.1.105 Retinol dehydrogenase
CH2OH
O
CH2OH
O 4.1.3.20
CH2OH
O
CH2OP
O
HOCH HCOH
C OH OH HO
CH2 CH2
C 2.7.6.1
2.7.7.3
Ribose-phosphate pyrophosphokinase
Pantetheine-phosphate adenylyltransferase
I
OH P O OH P O O-C-COO
Mannose-6-P HO OH OP UDP-Galactose O O OC-COO 2.7.7.4 Sulfate adenylyl transferase
H OH
1.1.1.130 3-Dehydro-L-gulonate 2-dehydrogenase 2.7.1.60 CH 2OP H OH OH OH OH OH OH OH
2.4.1.13 4.6.1.3 4.2.1.10 1.1.1.25 2.7.1.71 2.5.1.19 5.4.99.5
Shikimate-5 4.6.1.4
ACNH
1.1.1.157 3-Hydroxybutyryl-CoA dehydrogenase
HO OH HO OH OPPU HO OH OP O HO 3-Deoxy-D-arabino- Dehydro- Dehydro- Shikimate Shikimate-3-P Chorismate Prephenate D
2.7.7.6 RNA nucleotidyltransferase (DNA-directed)
1.1.1.158 UDP-N-acetylmuramate dehydrogenase
E OH HO OH OH 2.4.1.9
heptulosonate-7-P quinate shikimate enolpyruvate 3-P
2.7.7.7 DNA nucleotidyltransferase (DNA-directed)

Glucose-1-P PEP 2.7.7.9 UTPglucose-1-phosphate uridylyltransferase

S
1.1.1.169 2-Dehydropantoate 2-reductase NHAC NHCOCH 3 5.4.2.3 +
NHCOCH 3 +
X O O CH2COCOO 2.7.7.10 UTPhexose-1-phosphate uridylyltransferase
1.1.1.204 Xanthine dehydrogenase CH2CH(NH3) COO CH2CH(NH3) COO
1.1.1.205 IMP-dehydrogenase N-Ac-Mannosamine UDP-N-Ac-Glucosamine N-Ac-Glucosamine-1-P N-Ac-Glucosamine-6-P HO OH OH CH2OH
O
OH
CH2COO
CH2COCOO
4.2.1.51 2.7.7.12 UDP glucosehexose-1-phosphate
1.1.3.8
1.1.3.22
l-Gulonolactone oxidase
Xanthine oxidase
O 5.1.3.14 2.7.7.23
H H OH
2.3.1
.4 NH2
-OOC
O
CH2COO
O
CH2COO
1.3.1.13 2.7.7.13
uridylyltransferase
Mannose-1-phosphate guanylyltransferase
1.1.99.1 Choline dehydrogenase S
COO OH OH OH OH
5.3.1.8 Glucosamine-6-P HO OH OH
COO OH OH OH 2.7.7.14 Ethanolamine-phosphate cytidylyltransferase
Fumaryl 5.2.1.2 Maleyl 1.13.11.5 Homogentisate
O HOCH 2 C C C CO CH2OH 1.13.11.27 2.6.1.5 1.14.16.1 2.6.1.5
OH Hydroxyphenyl TYROSINE PHENYLALANINE Phenylpyruvate 2.7.7.15 Choline-phosphate cytidylyltransferase
E OP
1.1.99.5 Glycerol-3-phosphate dehydrogenase
OH H OH OH OH 4.3.1
1.2.1.3 Aldehyde dehydrogenase (NAD+)
COO -
OH OH H
acetoacetate acetoacetate 1.3.1.13 pyruvate 1.3.1.13
.5 2.7.7.18 Nicotinate-nucleotide adenylyltransferase
1.2.1.7
1.2.1.8
Benzaldehyde dehydrogenase (NADP+)
Betaine-aldehyde dehydrogenase S HOCH 2 C C C C HO OH OH HO OH HO OH
OH
Fructose SUCROSE 3.2.1.26 3.2.1.48
GLUCOSE CHOHCH 2NHCH 3 CHOHCH 2NH2 CH2CH2NH2 CH2CH(NH3) COO-
+
2.7.7.23
2.7.7.24
UDP-N-acetylglucosamine pyrophosphorylase
Glucose-1-phosphate thymidylyltransferase
H OH H H OH OH 4.1 CH2CH2NH2
C
1.2.1.11 Aspartate-semialdehyde dehydrogenase 1.1.1.19 1.13.99.1 3.1.3.25 .1.2 2.7.7.27 Glucose-1-phosphate adenylyltransferase
CH=CHCOO
1.2.1.12 Glyceraldehyde-3-phosphate dehydrogenase Gulonate Glucuronate Inositol Inositol-P 5.5.1.4 5 2.7.7.34 Glucose-1-phosphate guanylyltransferase
OH H OH OH OH H OH 5.4.2.2 OH OH OH OH Ubiquinone Cinnamate A 2.7.7.41 Phosphatidate cytidylyltransferase
ATP
1.2.1.13 Glyceraldehyde-3-phosphate dehydrogenase 1 1.14.16.2
1.2.1.16 Succinate-semialdehyde dehydrogenase (NAD(P)+) OH H OH OH 1.1.1.2 OH OH OH OH Menaquinone 2.7.7.43 N-Acylneuraminate cytidylyltransferase
1.2.1.18 Malonate semialdehyde dehydrogenase
(acetylating)
3.1.1.18 HOCH 2 C
H
C C
H
C
H
CO HOCH 2 C
H
C C
H
CO CO
HOCH 2 C C C C CO 1.1.1.14 H H OH H CH2OP
O
3.1.3.9 2.7.1.2 Epinephrine 2.1.1.28
Norepinephrine 1.14.17.1
Dopamine 4.1.1.28
Dopa
+
CH2CH(NH3) COO
OH
Tyramine 1.14.13.11 T 2.7.8.1
2.7.8.2
Ethanolamine phosphotransferase
Diacylglycerol cholinephosphotransferase
1.2.1.21 Glycolaldehyde dehydrogenase O O H O HOCH 2 C C C C CH2OH
2.6.1.16
2.7.1.1 (Adrenaline)
CHOHCH 2NH2
(Noradrenaline)
O E 2.7.8.3 Ceramide cholinephosphotransferase
Gulonolactone 1.1.3.8 2-Oxogulonolactone ASCORBATE OH OH H OH ADP 6
HN
C
2.7.8.5 CDPdiacylglycerolglycerol-3-
.1.
1.2.1.23 2-Oxoaldehyde dehydrogenase (NAD+) O 1.14.18.1 H2 I I CH=CHCOO
1.10.2.1 2.7
1.2.1.24 Succinate-semialdehyde dehydrogenase OH H OH Sorbitol HO OH CH2 OP 2.1 C Coumarate
phosphate 3-phosphatidyltransferase
1.1.1.45
OH H OH H
1.10.3.3 .1. -Tocopherol O
1.2.1.25 2-Oxoisovalerate dehydrogenase (acylating)
C COO- CO COO -
4 OH
1.1.1.49 O
OH
OCH 3
CHOHCH 2OH CH-COO O O
H 2.7.8.8 CDPdiacylglycerolserine O-phosphatidyltransferase
1.2.1.27 Methylmalonate-semialdehyde
dehydrogenase (acylating)
HOCH 2 C
H
C
OH
CO
H
HOCH 2 C
H
C
OH
CO HOCH2 C
H
C CO
O
CO CO
2.7.1.3 P-Glucono Glucose-6-P CH(OH)COO
Normetepinephrine
(Vitamin E)
O
+
NH3 O
OH
O
2.7.8.11 CDPdiacylglycerolinositol
3-phosphatidyltransferase
1.1.1.130
1.2.1.31
1.2.1.32
l-Aminoadipate-semialdehyde dehydrogenase
Aminomuconate-semialdehyde dehydrogenase
P 3-Dehydrogulonate 2, 3-Dioxogulonate Dehydroascorbate H H OH H 3.1
.1.1
7
lactone HO OH OH
OH
OCH 3
.3.
4
(Normetadrenaline) OCH 3 Dopaquinone
O NH
I
OH
I
L
2.8.3.5
2.8.3.6
3-Oxoacid CoA-transferase
3-Oxoadipate CoA-transferase
1.2.1.36 Retinal dehydrogenase E POCH2 C C C C COO - NADP + OH 1.4 OH
1.14.18.1
OH H OH H H OH H H 5.3.1.9 4-OH-3-Methoxy- 4-OH-3-Methoxy- Plastoquinone MELANIN THYROXINE LIGNIN Tannins Plant Pigments A HYDROLASES
N
1.2.1.41 Glutamate-5-semialdehyde dehydrogenase 5.3.1.8
6-P-Gluconate NADPH
OH OH H OH
1.2.1.52 Oxoglutarate dehydrogenase HOCH 2 C C C CHO HOCH 2 C C C CHO HOCH 2 C C CO CH 2OH
H H OH
D-mandelate phenylglycol M
3.1.1.3 Triacylglycerol lipase

T
1.2.3.5 Glyoxylate oxidase 3.1.1.4 Phospholipase A2
H OH H OH OH H OH OH
1.2.3.7
1.2.4.1
Indole-3-acetaldehyde oxidase
Pyruvate dehydrogenase (lipoamide)
O L-Xylose 4.1.1.34 D-Arabinose 5.3.1.3 D-Ribulose 2.7.1.47 HOCH 2 C C C CO CH2OP NADP +
H H HO
CH2OP
O NHCOCH 2NH2 NH N
OOC-CH-CH 2COO
O
I 3.1.1.5
3.1.1.7
Lysophospholipase
Acetylcholinesterase

N
OH OH H 1.1.1.44 NH N OOC N
1.2.4.2 Oxoglutarate dehydrogenase (lipoamide) HNCO C N C 3.1.1.17 Gluconolactonase
1.2.7.1 Pyruvate synthase S OH H H OH H OH H
Fructose-1-P 2.2.1.1 POCH2 C C C CO CH2OH H 2C CHO H 2C CHO
HC
CH
C
CH CH H 2N C CH 3.1.1.21 Retinyl-palmitate esterase
1.2.7.2 2-Oxobutyrate synthase
E
HOCH 2 C C C CH2OH HOCH 2 C C CO CH 2OH POCH2 C C CO CH2OH
H H H NADPH
OH OH H
OH OH
OC
NH
RP
HN C
NH
RP
H 2N C
N
RP H2 N
C
N
RP
H 2N C
N
RP H 2N
C N RP E 3.1.1.28 Acylcarnitine hydrolase
3.1.1.31 6-Phosphogluconolactonase
Fructose-6-P
1.3.1.1 Dihydrouracil dehydrogenase (NAD+)
1.3.1.2 Dihydropyrimidine dehydrogenase (NADP+)
S
H OH OH H OH
2.7.1.53
H OH
HOCH 2 C C C CH2OH
5.1.3.1
Glycinamide- 2.1.2.2 Formyl Formyl 6.3.5.3 6.3.3.1 5-Amino 4.1.1.21 5-Amino-4-imidazole 6.3.2.6 5-Amino-4-imidazole 4.3.2.2 5-Aminoimidazole O S 3.1.1.32 Phospholipase A1
1.3.1.8 Acyl-CoA dehydrogenase (NADP+) L-Arabitol L-Xylulose L-Xylulose-5-P H H
ribosyl-P glycinamide-R P glycinamidine-R P imidazole-R P carboxylate-R P (N-succinylcarboxamide)-R P carboxamide-R P C C N 3.1.2.1 Acetyl-CoA hydrolase
1.3.1.9
1.3.1.10
Enoyl-[acyl-carrier-protein] reductase (NADH)
Enoyl-[acyl-carrier-protein]
OH OH H H OH H H OH H OH OH OH
Ribitol
POCH2 C C CO CH2OH ATP H2 N
HCO C
CH 3.1.2.3
3.1.2.4
Succinyl-CoA hydrolase
3-Hydroxyisobutyryl-CoA hydrolase
HOCH 2 C C C CHO HOCH 2 C C C CH 2OH HOCH 2 C C C CHO OH OH H H 2.7.1.11 NH
O
NH O
2.1.2.3 NH N RP
3.1.2.11 Acetoacetyl-CoA hydrolase
reductase (NADPH, B-specific)
H2NCONH 2 NH2 H2 N C N O
1.3.1.13 Prephenate dehydrogenase (NADP+) H H OH 1.1.1.10 OH H OH OH H OH D-Ribulose-5-P POCH 2 C C CHO 3.1.3.11 H 2N COO OC
CO HN C CO HN C
C C N
Inosine Formylamido- 3.1.2.20 Acyl-CoA hydrolase
1.3.1.14 Orotate reductase (NADH) 2.7.1.47 ADP 6.3.4.13 Urea OC C
CO
OC C OC C CH HN C CH 3.2.2.2
3.1.3
.5 imidazole- 3.1.3.2 Acid phosphatase
L-Arabinose 5.3
.1. Xylitol D-Xylose H H H OH OH
N H NH N H NH N NH OC C HC C 3.1.3.3 Phosphoserine phosphatase
1.3.1.26
1.3.1.35
Dihydrodipicolinate reductase
Phosphatidylcholine desaturase OH H H 4 OH OH OH OH HOCH 2 C C C CHO 5.1.3.1
Erythrose-4-P 3.5.3.4 H
3.5.2.5
H
1.7.3.3
H
1.1.1.204
NH NH
1.1.3.22
N NH
2.4.2.1 carboxamide-R P 3.1.3.4 Phosphatidate phosphatase
1.3.3.3 Coproporphyrinogen oxidase
OH OH OH
H H HO
+ Allantoate Allantoin URATE 1.1.3.22 Xanthine Hypoxanthine 3.5.4.10 O
3.1.3.5 5-Nucleotidase
HOCH 2 C C C CHO HOCH 2 C C CO CH2OH POCH2 C C CO CH OH C C C CO CH2OP CH2(NH3)COO NH2 N 3.1.3.9 Glucose-6-phosphatase
1.3.3.4 Protoporphyrinogen oxidase POCH 2 C
2
D-Ribose .1.
4 NH2 N
N
HN C
GLYCINE
1.3.5.1 Succinate dehydrogenase (ubiquinone) H OH OH H H H H N CH 3.1.3.11 Fructose-bisphosphatase
1.3.99.1 Succinate dehydrogenase
L-Lyxose L-Ribulose 2.7.1.16
L-Ribulose-5-P 5.1.3.4 5.3.1.6
H OH OH OH H
2.6 .10
.1
N CH O
N
O O HC N
CH
N
NH2 N
C
OOC-CH-CH 2COO
HC
N
C
N RP
P 3.1.3.15 Histidinol-phosphatase
1.3.99.2
1.3.99.3
Butyryl-CoA dehydrogenase
Acyl-CoA dehydrogenase H OH
POCH 2 C C CO CH 2OH
4.1.2.-
2.2.1.2 Fructose- CH2OP
O NH2 1 . 4
1.
1.
20 O HC
N N -O P~O P~O P O CH
2 O HC
C
C
CH NH
C N
INOSINE-P U
3.1.3.25 myo-Inositol-1(or 4)-monophosphatase
3.1.3.27 Phosphatidylglycerophosphatase
1.1.1 OH H
2. O P O CH2 O
Fumarate Aspartate
1.3.99.7 Glutaryl-CoA dehydrogenase
1.3.99.10 Isovaleryl-CoA dehydrogenase
.9 HOCH 2 C C CO CH2OH D-Xylulose-5-P 1:6-bis-P OOCCH 2NHCH3
O O O N N RP(P) N
HC
C
C
CH (IMP) R 3.1.3.29 N-Acylneuraminate-9-phosphatase
3.1.3.31 Nucleotidase
Sarcosine 2.7.4.3
1.4.1.1 Alanine dehydrogenase OH H
D-Xylulose
2.7.1.17
2.7
OH OH
Glyoxylate
O
OH
4.6.1.1 ATP
OH OH
2.7.4.6
ADP
2.7.4.4 4.3.2.2
N NH RP
Adenylo- 6.3.4.4 O
N
I 3.1.4.2
3.1.4.3
Glycerophosphocholine phosphodiesterase
Phospholipase C
1.4.1.2 Glutamate dehydrogenase
.1. P-Ribosyl 1.5.99.2 ADENOSINE-P C
N
1.4.1.7 Serine dehydrogenase
15 Cyclic AMP (AMP) succinate 3.1.4.6
HN C CH
3.1.4.4 Phospholipase D
1.4.1.8 Valine dehydrogenase (NADP+)
H H H amine 1.4.4.2 1.17.4.1 1.1.1.205 OC C
N RP E
3.1.4.10 1-Phosphatidylinositol phosphodieterase
1.4.1.9 Leucine dehydrogenase H H H OH
OOCCH 2N(CH3)2 d-ADP Adenine 2.4.2.1
N
H
3.1.4.12 Sphingomyelin phosphodiesterase
3.2.1.21 -Glucosidase
S
1.4.1.10 Glycine dehydrogenase POCH 2 C C C CHO
1.4.1.14 Glutamate synthase (NADH) POCH2 C C C C CO CH2OP 4.1.2.13 Dimethylglycine 2.7.4.6 3.5.4
XANTHOSINE-P 3.2.1.23 -Galactosidase
Chloroplast Stroma 2.7.7.7 2.4.2.15
1.4.1.19
1.4.3.1
Tryptophan dehydrogenase
d-Aspartate oxidase PHOTO- PHOTO-
OH OH OH
D-Ribose-5-P
OH OH OH H
Sedoheptulose-PP 2.1.1.5 2.7.7
.7 DNA 2.7.7.7
d-GTP d-GDP .3 (XMP)
O
3.2.1.26 -Fructofuranosidase
3.2.1.45 Glucosylceramidase
1.1 Guanine 6.3.4.1 C N
1.4.3.2
1.4.3.4
l-Amino-acid oxidase
Amine oxidase (flavin-containing)
P SYSTEM II
2H +
SYSTEM I
ATP 2.2.1.1 OOCCH2N(CH3)3
+
d-ATP 2.7 d-CTP
7 .4.1 2.4.2
.1 6.3.5.2
HN C CH
3.2.1.46 Galactosylceramidase
3.2.1.48 Sucrose a-glucosidase
Chlorophyll .7 H2 N C
1.4.3.8 Ethanolamine oxidase H Pheophytin Ferredoxin 3.6.1.34
ADP+Pi
4.1.2.13
Betaine 2.7.7.6
.7
2.7.4.6 2.7.4.8
N
C
N RP 3.2.2.2 Inosine nucleosidase
1.4.4.2 Glycine dehydrogenase (decarboxylating)
O 2e*- 3H+
POCH 2CHOHCHO FOLIC ATP RNA 2.7.7.6
GTP GDP
GUANOSINE-P
3.3.1.1
3.5.1.1
Adenosylhomocysteinase
Asparaginase
3-P-Glyceraldehyde
1.5.1.2 Pyrroline-5-carboxylate reductase
1.2.1.8 2.1.2.1 ACID 2.7
TTP 2.7. 1.17.4
1.5.1.3 Dihydrofolate reductase
T 2e* PQ 2.2.1.1
C1
.7.6 .1 (GMP)
3.5.1.2 Glutaminase

2e*
1.5.1.5 Methylenetetrahydrofolate reductase (NADP+) Cyt. HOCH2CO CH2OP .1 + 4.6 3.5.1.6 -Ureidopropionase
5.3.1 2.4.2.14 OHCCH 2N(CH3)3
1.5.1.6
1.5.1.7
Formyltetrahydrofolate dehydrogenase
Saccharopine dehydrogenase (NAD+, O b 3.6.1.3 Dihydroxy- Pi Pi 6.3.4.7 Betaine POOL
0 O 2.7 O O
NH2
C P
3.5.1.9 Arylformamidase
3.5.1.18 Succinyl-diaminopimelate desuccinylase
4.2.1.2 TDP
1.5.1.8
l-lysine-forming)
Saccharopine dehydrogenase (NADP+,
S PQH2
acetone-P 5.3.1
.1
NAD+ aldehyde 4.1.2.5
CH3
HN
C
CH-CH3
HN
O
C
C CH3
.7.
6 2.7
.4.9 HN
C
C-CH3
HN
C
CH
OC
NCH
CH Y 3.5.1.22 Pantothenase
3.5.1.23 Ceramidase
(Glycerone-P)
l-lysine-forming) Y e- Thylakoid 2H
+

+
2.7.1.28
+
1.1.99.1
CH3
H2NCH 2 CHCOO H2NCONHCH 2CHCOO
OC
NH
CH 2
OC CH
OC
N
CH
DP
2.1.1.45 OC CH
N DP
N
DP R 3.5.2.2
3.5.2.3
Dihydropyrimidinase
Dihydroorotase
1.5.1.9 Saccharopine dehydrogenase (NAD+, 3.5.4.12 2.7.4.14
l-glutamate-forming) N Mn Membrane f
PC
NADP
1.2.1.12
HOCH2CH2N (CH3) 3
CHOLINE 3-Amino- 3.5.1.6
-Ureido 3.5.2.2
Dihydro
NH
1.3.1.2 Thymine
2.4.2.4
THYMIDINE-P d-UMP d-CMP d-CDP I 3.5.2.5 Allantoinase

T
3.5.2.7 Imidazolonepropionase
1.5.1.10 Saccharopine dehydrogenase (NADP+,
P680 2H+ Tr
PC 3H +
H
+
HOCH 2CH(OH)CHO 1.2.1.13 + isobutyrate isobutyrate thymine O O 2.4.2 NH 2 M 3.5.2.10 Creatininase
l-glutamate-forming)
ans P700 ns H Glyceraldehyde HOCH2CH(NH3)COO 2. C C C
H NADH 4.2.1.22 1. CH2 .4
+
2H+
located proto H H H HN HN CH
I
1.5.1.12 1-Pyrroline-5-carboxylate dehydrogenase
+
1. N CH 3.5.3.1 Arginase
2H2O H
+

SERINE 1.17.4.1
NADPH+H + 13
+ +
1.5.3.1 Sarcosine oxidase H
+
OC CH2 OC CH 3.5.3.4 Allantoicase
OC CH
E 2.6.1.51
+
H + H2NCONHCH 2CH 2COO
1.5.99.1
1.5.99.2
Sarcosine dehydrogenase
Dimethylglycine dehydrogenase
O2 H
+
H H+
H H
CH2OP
O
POCH 2CHOHCOOP 1.4.1.7
4.1.1.11 H2NCH 2CH2COO
3.5.1.6 Carbamoyl 3.5.2.2 Dihydro-
NH
1.3.1.2
N H
3.5.4.1 NH
CDP D 3.5.3.6
3.5.4.1
Arginine deiminase
Cytosine deaminase
S Thylakoid Lumen -Alanine Uracil Cytosine
1.5.99.8 Proline dehydrogenase
++ POCH 2 C C CO CH 2OP 2.7.6.1 1:3-bis-P-Glycerate HOCH2COCOO -OOC
-alanine uracil O O
NH 2
C I 3.5.4.3 Guanine deaminase
CH 2.7.4.6
1.6.4.1 Cystine reductase (NADH) O 3.5.4.6 AMP deaminase
I Thylakoid Membrane Mg OP O P O O C
1.6.5.3 NADH dehydrogenase (ubiquinone) OH OH Hydroxy- 3.1.3.3
NH2 CH2 C
CH2
C
CH HN
C
CH HN CH
C HN CH N
CH N 3.5.4.10 IMP cyclohydrolase
1.6.6.1
1.6.6.2
Nitrate reductase (NADH)
Nitrate reductase [NAD(P)H] S Ribulose-1:5-bis-P OH OH
P-Ribosyl-PP pyruvate
+
OC
N
CH-COO
HN
OC CH-COO
HN
OC C-COO OC
N
C-COO OC N CH
2.4.2.9 OC
N
CH OC
N
RPPP E
3.5.4.12 dCMP deaminase
3.5.4.19 Phosphoribosyl-AMP cyclohydrolase
Chloroplast Stroma RPPP
1.6.6.3
1.6.6.4
Nitrate reductase (NADPH)
Nitrite reductase [NAD(P)H]
Fixation CO2 ADP P OCH2CH(NH3)COO
Phospho-
H
Carbamoyl
NH
Dihydro Orotate Orotidine-P
NH
Uridine-P UDP
RP
URIDINE-
RP 6.3.4.2
CYTIDINE- S
3.6.1.3 Adenosinetriphosphatase
3.6.1.15 Nucleoside-triphosphatase
3.5.2.3 4.1.1.23 (UMP) 2.7.4.4
1.6.6.8 GMP reductase 2.7.2.3 serine aspartate orotate 1.3.1.14 2.4.2.10 2.7.4.6 triphosphate triphosphate 3.6.1.31 Phosphoribosyl-ATP pyrophosphatase
1.7.3.3
1.7.7.1
Urate oxidase
Ferredoxinnitrate reductase O2 4.1.1.39
1.1.1.29 (UTP) (CTP)
3.6.1.34 H+-transporting ATP synthase
3.7.1.2 Fumarylacetoacetase
1.7.99.4 Nitrate reductase COO
HO HO
COO ATP 2.6.1.52
2.6.1.22
NH2 NH2
3.7.1.3
3.9.1.1
Kynureninase
Phosphoamidase
1.8.1.3 Hypotaurine dehydrogenase COO H H H H H H H H H H CONH 2
+ C N OC N N H H
1.8.1.4 Dihydrolipoamide dehydrogenase
C C NH C
-Linolenate
1.14.99.25 P OCH2 C C C C N P OCH 2 C C C C NH P OCH 2 C C CO CH2
1.8.2.1 Sulfite dehydrogenase Linoleate Arachidonate 1.13.11.34 Leukotriene B4 OH
POCH2CHOH COO
1.1.1.95
P OCH2COCOO CH CH CH
P OCH 2 C C C CH
LYSASES
1.8.3.1 Sulfite oxidase
COO 5.3 O
3-P-Glycerate P-Hydroxy- OH OH HC
N
C
N OH OH HC
N
C
N OH OH HC
N
C
N OH OH HN N
4.1.1.1
4.1.1.3
Pyruvate decarboxylase
Oxaloacetate decarboxylase
.99 COO O O RP
1.8.7.1 Sulfite reductase (ferredoxin)
1.3.1.35 1.1
.3
COO pyruvate 3.6.1.31
RP(PP)
3.5.4.19
RP
C
1.8.99.1 Sulfite reductase 4.9
9.1 O 2.4.2.17
P-Ribosyl-ATP P-Ribosyl-AMP P-Ribosylformimino P-Ribulosylformimino Imidazole H
4.1.1.4
4.1.1.9
Acetoacetate decarboxylase
Malonyl-CoA decarboxylase
L COSCoA
1.8.99.2 Adenylsulphate reductase
1.9.3.1 Cytochrome-c oxidase
CO-S-ACP
HO OH 5.3.99.5
HO
OH 2.7.1.31 5-aminoimidazole- 5.3.1.16 5-aminoimidazole- glycerol-P 4.1.1.11 Aspartate 1-decarboxylase
C CH 2CHCOO
1.10.2.1 l-Ascorbatecytochrome-b5 reductase
I Oleoyl-CoA Palmitoleoyl-ACP Prostaglandin PGE 2 Thromboxane B2 POCH2CH(O P) COO
HC
+ carboxamide-R P +
carboxamide-R P+ 4.1.1.12 Aspartate 4-decarboxylase
HOCH2CH(OH) COO NH C + HC C CH2COCH 2OP 4.1.1.15 Glutamate decarboxylase
1.10.2.2 Ubiquinolcytochrome-c reductase 1.14.99.5 2, 3-Diphospho- 5.4.2.1 N NHCOCH 2CH2NH2 HC CH2CH(NH 3)COO HC C CH2CH(NH 3)CHO HC C CH 2CH(NH 3)CH2OH HC C CH2CH(NH 3)CH2OP
1.10.3.3 l-Ascorbate oxidase
1.10.99.1 Plastoquinolplastocyanin reductase
P COSCoA CH3(CH2)14CH=CHCOS-CoA CH3(CH2)14CH(OH)CH 2COS
COS-CoA CH3(CH2)14COCH 2COS-CoA
glycerate Glycerate C
H Carnosine N
CH
NH
N NH N NH N NH
N
C
NH
4.2.1.19 4.1.1.17
4.1.1.20
Ornithine decarboxylase
Diaminopimelate decarboxylase
1.13.11.1 Catechol 1,2-dioxygenase I Stearoyl-CoA Dehydrostearoyl-CoA OH-Stearoyl-CoA Oxostearoyl-CoA CH 3COO
CH CH CH H 4 1.1.21 Phosphoribosylaminoimidazole carboxylase
1.13.11.2 Catechol 2,3-dioxygenase CH3(CH2)14COCH 2COS-CoA
HISTIDINE Histidinal Histidinol Histidinol-P Imidazole 4.1.1.22 Histidine decarboxylase
1.13.11.5 Homogentisate 1,2-dioxygenase
1.13.11.6 3-Hydroxyanthranilate 3,4-dioxygenase
D Endoplasmic Reticulum ACETATE 4.1.1.22 1.1.1.23 1.1.1.23 3.1.3.15 2.6.1.9
acetol-P 4.1.1.23
4.1.1.25
Orotidine-5-phosphate decarboxylase
Tyrosine decarboxylase
CH3(CH2)14COS-ACP CH 3(CH2)14COSCoA HOCH2CH(O P)COO HC C CH2CH2NH2
4.3.1.3
1.13.11.11 Tryptophan 2,3-dioxygenase Chain elongation Mitochondrial 4.1.1.28 Aromatic-L-amino-acid decarboxylase
Palmitoyl-ACP Palmitoyl-CoA 2-P-Glycerate OOC CHCH 2CH2COO OC CHCH 2CH2COO CH C CH CHCOO
B
1.13.11.20 Cysteine dioxygenase N NH 4.1.1.29 Sulfoalanine decarboxylase
1.13.11.21 -Carotene 15,15-dioxygenase CH3(CH2)n CH=CHCOS-CoA CH 3(CH2)n CH(OH)CH 2COSACP CH 3(CH2)n COCH 2COSACP
1.2.1.4 C HN NH N NH N NH 4.3.1.3 4.1.1.32 Phosphoenolpyruvate carboxykinase (GTP)
1.13.11.27 4-Hydroxyphenylpyruvate dioxygenase
I 1.3.1.9 4.2.1.60 1.1.1.100
H HISTAMINE CH
3.5.2.7 CH
4.2.1.49 CH 4.1.1.33 Diphosphomevalonate decarboxylase
1.13.11.34 Arachidonate 5-lipoxygenase ACYL-ACP 2, 3-Enoyl-ACP 4.2.1.61
3-OH-Acyl-ACP 3-Oxoacyl-ACP Formimino Imidazolone Urocanate 4.1.1.34 Dehydro-l-gulonate decarboxylase
1.13.99.1 myo-lnositol oxygenase
1.14.11.1 g-Butyrobetaine dioxygenase
O 1.3.1.10 2.3.1.41
4.2.1.11
CH3CH 2OH
ETHANOL 2.3
glutamate propionate 4.1.1.36
4.1.1.37
Phosphopantothenoylcysteine decarboxylase
Uroporphyrinogen decarboxylase
2.1.3.2
1.14.11.2 Procollagen-proline dioxygenase S CH3(CH2)5CH=CHCH 2COSACP
4.2.1.6 CH (CH ) CH(OH)CH COSACP
.1.3
0
4.1.1.39 Ribulose-bisphosphate carboxylase
CH3(CH2)6CH2CH 2COSACP 3, 4-Decenoyl-ACP CH 3(CH2)6COCH 2COSACP + 4.1.1.41 Methylmalonyl-CoA decarboxylase
Y 0
1.14.11.8 Trimethyllysine dioxygenase 3 2 6 2
Decanoyl-ACP
1.1.1.100
3-OH-Decanoyl-ACP 3-Oxo-Decanoyl-ACP
CH2CO-OCH2CH(NH 3)COO 2-
HSO3- Phosphoadenylyl- Adenylylsulphate
1.3.1 1.1.1.1 4.1.1.43 Phenylpyruvate decarboxylase
1.14.12.1 Anthranilate 1,2-dioxygenase
.9 CH3(CH2)6CH=CHCOSACP Acetylserine HS SO 4 1.2.1.32
N
(deaminating, decarboxylating) 2.7.7.4 4.1.1.45 Aminocarboxymuconate-
0 1.8.99.1 1.8.99.2 2.7.1.25 (APS)
1.14.13.5 Imidazoleacetate 4-monooxygenase 2, 3-Decenoyl-ACP 4 .2.1.6 2.3.1.41 CH2=C(OP ) COO +
sulphate semialdehyde decarboxylase
CH3CHO
1.14.13.9 Kynurenine 3-monooxygenase
1.14.13.11 trans-Cinnamate 4-monooxygenase
T CH 3(CH2)2CH 2CH2COSACP CH3(CH2)2CH=CHCO-S-ACP CH3(CH2)2CH(OH)CH 2COSACP CH3(CH2)2COCH 2COSACP P-enolpyruvate Acetaldehyde
S-CH 2CH(NH 3)COO
+
4.2
.99 +
+
CH2CH(NH 3)COO
(PAPS)
+
4.1.1.48
4.1.1.49
Indole-3-glycerol-phosphate synthase
Phosphoenolpyruvate carboxykinase (ATP)
1.1.1.100 .8 HSCH 2CH(NH
1.14.13.12 Benzoate 4-monooxygenase
1.14.13.39 Nitric oxide synthase
H Hexanoyl-ACP
1.3.1.9
2, 3-Hexenoyl-ACP
4.2.1.59
3-OH-Hexanoyl-ACP 3-Oxo-Hexanoyl-ACP
HS
S-CH 2CH(NH 3)COO 3)COO
4.4.1.1
+
SCH 2CH2CH(NH 3)COO 4.2.1.22
+
HSCH 2CH2CH(NH 3)COO
2.1.1.13
CH 3 - SCH 2CH2CH(NH 3)COO 4.1.1.50
4.1.1.65
Adenosylmethionine decarboxylase
Phosphatidylserine decarboxylase
2.3.1.41
1.14.16.1 Phenylalanine 4-monooxygenase E CH3CH=CHCO.S-ACP CYSTINE 1.6.4.1 CYSTEINE
4.2.99.9
Cystathionine 4.4.1.8
Homocysteine 2.1.1.14
METHIONINE 4.1.1.71
4.1.2.5
2-Oxoglutarate decarboxylase
Threonine aldolase
S
1.14.16.2 Tyrosine 3-monooxygenase
1.14.16.4 Tryptophan 5-monooxygenase CH3CH2CH2COSACP CH3CH=CHCO-S-ACP CH3CH(OH)CH 2COS-ACP CH3COCH 2COSACP ADP .1.
1
1.13.11.20 Adenosyl 4.1.2.12 Ketopantoaldolase
1.3.1.9 4.2.1.58 1.1.1.100 4.1 4.4.1.15 3.3.1.1 Adenosyl 2.5.1.6
I Butanoyl-ACP Crotonoyl-ACP 3-OH-Butanoyl-ACP Acetoacetyl-ACP
1.14.17.1 Dopamine -monooxygenase + 4.1.2.13 Fructose-bisphosphate aldolase
HOOCCH 2CO-S-ACP +
SCH 2CH2CH(NH 3)COO 4.1.2.14 2-Dehydro-3-deoxyphosphogluconate aldolase
1.14.18.1 Monophenol monooxygenase
R-CH2COO CH2OH CH2OH Malonyl-ACP 2.7.1.40 Glutamate CH 3 - SCH 2CH 2CH(NH 3)COO
S
+ +
1 14.99.1 Prostaglandin synthase
1.1.1.8 HO 2SCH 2CH(NH 3 )COO S-Adenosyl + 4.1.3.1 Isocitrate lyase
1 14.99.5 Stearoyl-CoA desaturase
CH3(CH2)n+2COS-CoA 6.2.1.3 3.1.2.20 FATTY ACID
HOCH
CH2 OH
HOCH
CH2O P
2.3.1.41 ATP 4.4.1.15 HSO3- Cysteine
HO3SCH 2CH(NH 3)COO
Cysteate homocysteine 2.1.1.10
4.1.3.2
4.1.3.4
Malate synthase
Hydroxymethylglutaryl-CoA lyase
1.14.99.7 Squalene monooxygenase
1.14.99.25 Linoleoyl-CoA desaturase 4.1 4.1.1.50 4.1.3.5 Hydroxymethylglutaryl-CoA synthase
1.17.4.1 Ribonucleoside-diphosphate reductase ACYL-CoA Glycerol
2.7.1.30
3-P-Glycerol 2.3.1.39 .1.
2 HO2SCH 2COCOO sulphinate .1. 6.3.2
.2 +
CH2SH 2.1.1.20 4.1.3.7 Citrate (si)-synthase
1.18.6.1 Nitrogenase (Cytosol)
KETONE BODIES 3.7
3-Sulphinyl
2 9 OOCCH(NH 3)CH2CH2CONHCHCOO 4.1.3.8 ATP citrate (pro-S)-lyase
2.3.1.15 CH3CO COO
2.3.1.51 CH3COCH 3 CH3CH(OH)CH 2COO
pyruvate HO2SCH 2CH2NH2 HO3SCH 2CH2NH2 -Glutamylcysteine 4.1.3.16 4-Hydroxy-2-oxoglutarate aldolase
TRANSFERASES
2.1.1.1 Nicotinamide N-methyltransferase
2.3.1.7 Acetone 3-OH-Butyrate
HOOCCH 2CO-SCoA
Malonyl-Co-A PYRUVATE 1.4.1.1
2.6.1.2
+
CH3CH(NH3)COO
ALANINE 4.1.1.29
Hypotaurine 1.8.1.3
Taurine Glycine
CH2SH
4.1.3.18
4.1.3.20
Acetolactate synthase
N-Acylneuraminate-9-phosphate synthase
2.1.1.2 Guanidinoacetate N-methyltransferase Carnitine 3.1.1.3
CH2O-CO-R
CH2O-CO-R CH2O-CO-R 2.7.8.5 1.2.4.1 4.1.2.5 + 6.3.2
.3
+ 4.1.3.21 Homocitrate synthase
2.1.1.3
2.1.1.4
Thetinhomocysteine S-methyltransferase
Acetylserotonin N-methyltransferase
L O-Acyl-carnitine
R-CO-OCH R-CO-OCH R-CO-OCH
4.1.1.4 1.1.1.30
CH 3CO-S-ACP 4.1.1.9
2.3.1.12
1.8.1.4
4.1.3
.18
OOCCH2CH2COOCH2CH2CH(NH 3)COO
Succinylhomoserine
OOCCH(NH 3)CH2CH2CONHCHCONHCH 2COO
Glutathione
4.1.3.22
4.1.3.27
Citramalate lyase
Anthranilate synthase
2.1.1.5 Betainehomocysteine S-methyltransferase I CH2O-CO-R"
CH2OH CH2O P
CH3COCH 2COO Acetyl-ACP 4.1.1.12
+ Bile Acids 4.1.99.1 Tryptophanase
Triacylglycerol Acetoacetate 1.1 CH3CH(OH)CH(NH 3)COO + + 4.2.1.2 Fumarate hydratase
2.1.1.6 Catechol O-methyl transferase
P O-Acyl-carnitine Diacyl .1.2 2.6.1.18 POCH 2CH2CH(NH 3)COO HOCH 2CH2CH(NH 3)COO
3.1.3.4 2.7.1.107 Phosphatidate
7 4.2.1.3 Aconitate hydratase
2.1.1.10 Homocysteine S-methyltransferase
FAT 2.3.1.20
glycerol THREONINE O-Phospho- 2.7.1.39Homoserine HOCH 2 C(CH 3)2COCOO
I
2.1.1.13 5-Methyltetrahydrofolatehomocysteine 3.1.1.28 3.1.2.11 4.2.1.4 Citrate dehydratase
CH3CH(OH)COO
4.2.99.2 2.3.1.46 4.1.2.12
S-methyl transferase 2.3.1.38
LACTATE homoserine HCHO Oxopantoate 4.2.1.9 Dihydroxy-acid dehydratase
2.1.1.14 5-Methyltetrahydropteroyltriglutamate
D ATP OHCCH 2COO
4.1.3
.18 CH3 CH3
CH3
+
4.2.1.10 3-Dehydroxyquinate dehydratase
homocysteine S-methyltransferase CH3(CH2)n CH2CH2COSCoA 1.1.1.3 CHCH(NH 3)COO 1.1.1.169 4.2.1.11 Phosphopyruvate hydratase (enolase)
CH3(CH2)n CH=CHCOSCoA
4.2.1.17
CH3(CH n CH(OH)CH 2COSCoA CH3(CH2)n COCH 2COSCoA
GTP 4.2 Malonic COO C (OH)CH(OH)COO
2.1.1.17 Phosphatidylethanolamine N-methyltransferase
ACYL-CoA 1.3.99.3
2, 3-Enoyl-CoA 3-OH-Acyl-CoA 1.1.1.35
3-Oxoacyl-CoA
2.3.1.16
.1. 4.2.1.16
CHCOCOO CH3
4.2.1.13 l-Serine dehydratase
2.1.1.20
2.1.1.28
Glycine N-methyltransferase
Phenylethanolamine N-methyltransferase D (Mitochondria) CH 3 COSCoA
52 semi- CH3COC(OH)CH 3
2-Acetolactate
1.1.1.86
CH3
2-3-Dihydroxy 4.2.1.9
CH3
2-Oxo- 1.4.1.8 VALINE
2.6.1.32
HOCH 2 C(CH 3)2CH(OH)COO
4.2.1.16
4.2.1.17
Threonine dehydratase
Enoyl-CoA hydratase
2.1.1.45 Thymidylate synthase
E 1.2.1.18 aldehyde Pantoate 4.2.1.18 Methylglutaconyl-CoA hydratase
2.1.1.71 Phosphatidyl-N-methylethanolamine
CH3(CH2)2CH2CH2COSCoA
1.3.99.3
CH3(CH2)2CH=CHCOSCoA
4.2.1.17
CH3(CH2)2CH(OH)CH 2COSCoA
1.1.1.35
CH3(CH2)2COCH 2COSCoA
2.3.1.16 ACETYL-CoA CH3CH2COCOO
Oxobutyrate
isovalerate isovalerate -Alanine 4.2.1.19 Imidazoleglycerol-phosphate dehydratase
N-methyltransferase G Hexanoyl-CoA 2, 3-Hexenoyl-CoA 3-OH-Hexanoyl-CoA 3-Oxohexanoyl-CoA 1.2.1.25
3.5.1.22
6.3.2.1
4.2.1.20 Tryptophan synthase
2.3.1.9 CH3 CH3 CH3 CH3 4.2.1.22 Cystathionine B-synthase
R
2.1.2.1 Glycine hydroxymethyltransferase
2.1.2.2 Phosphoribosylglycinamide formyltransferase HOCH 2CHCOO HOCH 2CHCOS-CoA- CH2 = CCOSCoA CH3CHCO-SCoA 4.2.1.24 Porphobilinogen synthase
CH3CH2CH2COSCoA CH3CH=CHCOSCoA HOCH 2 C(CH3)2CH(OH)CO NHCH 2CH2COO
CH3CH(OH)CH 2COSCoA CH3COCH 2COSCoA 3.1.2.4 4.2.1.17
A 4.1 1.3.99.3 4.2.1.33 3-Isopropylmalate dehydratase
2.1.2.3 Phosphoribosylaminoimidazole
carboxamide formyltransferase Butanoyl-CoA
1.3.99.2
Crotonoyl-CoA
4.2.1.55
3-OH-Butanoyl-CoA
1.1.1.157
Acetoacetyl-CoA .3.1 3-Hydroxy- 3-Hydroxy- Methyl Isobutyryl-CoA PANTOTHENATE 4.2 1.46 dTDPglucose 4,6-dehydratase
CH3 8
4.1.3.5 isobutyrate Isobutyryl-CoA acrylyl-CoA
2.1.2.5
2.1.2.10
Glutamate formiminotransferase
Aminomethyl transferase D Odd C Fatty acids 2.6.1.4
4
4.1.1.32 OHCCHCOO 1.1.1
.31
2.7.1.33
4.2.1.47
4.2.1.49
GDPmannose 4,6-dehydratase
Urocanate hydratase
2.1.3.1 Methylmalonyl-CoA carboxyltransferase A CH 3CH2CH 2CH2COSCoA CH3CH2CH=CHCOSCoA CH3CH2CH(OH)CH 2COSCoA CH3CH2COCH 2COSCoA Methylmalonyl CH 3 4.2.1.51 Prephenate dehydratase
1.1.1.35 2.6.1.4 CH3 CH3 +
2.1.3.2 Aspartate carbamoyltransferase
T Pentanoyl-CoA Pentenoyl-CoA 3-OH-Pentanoyl-CoA 3-Oxopentanoyl-CoA semialdehyde COO CHCOCOO
CHCH(NH 3)COO P OCH 2C(CH 3)2CH(OH)CONHCH 2CH2COO 4.2.1.52
4.2.1.55
Dihydrodipicolinate synthase
3-Hydroxybutyryl-CoA dehydratase
2.1.3.3 Ornithine carbamoyltransferase 1.1.1.39 C(OH)CH(OH)COO
CH3CH2 4-P-Pantothenate
I
2.1.4.1 Glycine amidinotransferase CH 2O-CO-R 4.2.1.58 Crotonoyl-[acyl-carrier-protein] hydratase
CH 2O-CO-R CH3COC(OH)CH 2CH3 CH3CH2 CH3CH2
2.2.1.1 Transketolase
CH2O-CO-R OHCCOO 4.1.3.5 4.1.3.4 2.3.1 2.6.1.32 Cysteine 4.2.1.59 3-Hydroxyoctanoyl-[acyl-carrier
OH OH 2.7.7.41 Glyoxylate .16 2-Aceto-2- 2:3-Di-OH-
4.2.1.9
2-Oxo-3-methyl ISOLEUCINE
6.3.2.5
2.2.1.2
2.3.1.1
Transaldolase
Amino-acid N-acetyltransferase
O R'-CO-OCH O
R'-CO-OCH O COO
+
CH 2O PO CH 2CHNH 3
R'-CO-OCH O
CH2COO 4.1.3.8 OOCCOCH 2COO
hydroxy- 1.1.1.86 3-methylvalerate valerate
COO
4.2.1.60
protein] dehydratase
3-Hydroxydecanoyl-[acyl-carrier
2.3.1.4 Glucosamine-phosphate N-acetyltransferase N CH2O-PO 1.3.99.7
- Serine
CH2O POCMP 1.1.1.79
1.2.3.5
CH3C(OH)CH 2COSCoA OXALOACETATE butyrate
P OCH 2C(CH 3)2CH(OH)CONHCH 2CH 2CO NHCHCH 2SH
4-P-Pantothenylcysteine
protein] dehydratase
2.3.1.5 Arylamine N-acetyltransferase O - HO OH O
2.7.8.8
O
-OH--Methyl- 4.2.1.1 CH3 CH 3 CH 3 1.2.1.25
4.2.1.61 3-Hydroxypalmitoyl-[acyl-carrier protein]
2.3.1.6 Choline O-acetyltransferase
PHOSPHATIDYL CDP-diacyl HOCH 2COO
glutaryl-CoA 8
CH3 dehydratase
2.3.1.7 Carnitine O-acetyltransferase OH
2.7.8.11 Inositol glycerol Glycolate 1.1.1.37 CH3COCHCOSCoA CH3CH(OH)CHCOSCoA CH3CH=CHCOSCoA CH3CH 2CHCOSCoA 4.1.1.36 4.2.1.75 Uroporphyrinogen-III synthase
2.3.1.8 Phosphate acetyltransferase
Phosphatidyl SERINE CH2COO OOCCH(OH)CH 2COO
4.1.1.12
2-Methylaceto-1.1.1.35 2-Methyl-3-4.2.1.17Tiglyl-CoA 2 Methylbutyryl- 4.2.1.80 2-Oxopent-4-enoate hydratase
2.3.1.9 Acetyl-CoA C-acetyltransferase 1.2.1.21 HOOC-COOH 1.3.99.3
4.2.99.2 Threonine synthase
2.3.1.12 Dihydrolipoamide S-acetyltransferase inositol CH2O-CO-R CH 2O-CO-R CH2O-CO-R
Oxalate 1.1.1.34 C(OH)COO MALATE acetyl-CoA hydroxy- CoA P OCH 2C(CH 3)2CH(OH)CONHCH 2CH 2CO NHCH 2CH 2SH 4.2.99.8 Cysteine synthase
2.3.1.15 Glycerol-3-phosphate O-acyltransferase R'-CO-OCH O O HCO-CO-R R'-CO-OCH O 2.7.8.5 HOCH 2CHO CH2COO
4.1.3.7
4.2.1.2
2.6.1.1 CH 3CH2COSCoA butyryl-CoA 4-P-Pantetheine 4.2.99.9
4.3.1.1
O-Succinylhomoserine (thiol)-lyase
Aspartate ammonia-lyase
P 2 Propanoyl-CoA
2.3.1.16 Acetyl-CoA C-acyltransferase 4.1.1.65
CH 2O-CO-R CH2 O-POCH 2CH(OH)CH 2 O-P-OCH 2 CH2O-PO CH 2CHOHCH 2OH Glycol .3. 1.4.3.1 4.3.1.2 Methylaspartate ammonia-lyase
4.1
2.3.1.20 Diacylglycerol O-acyltransferase 2.7.7.3
2.3.1.23 Lysolecithin acyltransferase
H R'-CO-OCH O
O - O - O- aldehyde CH2COO
CITRATE OOCCH=CHCOO 2.1.3.1 COOH COOH
+ 4.3.1.3 Histidine ammonia-lyase
2.3.1.24 Sphingosine N-acyltransferase + Cardiolipin Phosphatidylglycerol CH3C(OH)CH 2CHO
FUMARATE 4.1.1.41 6.4.1.3 (CH3)2CHCH 2 CH(NH 3)COO 4.3.1.5 Phenylalanine ammonia-lyase
2.3.1.30 Serine O-acetyltransferase
O CH 2O P OCH 2CH2 NH 3
-
+ +
1.4.3.8 Mevaldate 4.2.1.3
HOOCCHO 4.3 5.1.99.1
(CH3)2CHC(OH)CH 2COO (CH3)2CHCHCH(OH)COO (CH3)2CHCH 2COCOO 2.6.1.6
LEUCINE
ADP- OCH2 C(CH 3)2CH(OH)CONHCH 2CH2CO NHCH 2CH2SH
Dephospho-Coenzyme A
4.3.2.1 Argininosuccinate lyase
2.3.1.37 5-Aminolevulinate synthase CPP- OCH 2CH2 NH3 POCH2CH2 NH3 .1. 2-Isopropyl- 3-Isopropyl- 1.1.1.85 Oxoleucine 4.3.2.2 Adenylosuccinate lyase
S
O
2.3.1.38 [Acyl-carrier-protein] S-acetyltransferase 2.7.8.1 2.7.7.14 2.7.1.82
+
Glyoxylate 1 4.2.1.33 4.4.1.1 Cystathionine g-lyase
2.3.1.39 [Acyl-carrier-protein] Phosphatidyl CDP-Ethanolamine Ethanolamine-P HOCH 2CH 2NH 3
1.1.1.32 1.3.5.1 malate malate 1.4.1.9
2.7.1.24 4.4.1.8 Cystathionine -lyase
S-malonytransferase P ethanolamine CH2O-CO-R
CH2OH Ethanolamine CHOHCOO
+
CH3
OOC-CH-COSCoA 4.2.1.18
CH3 CH3 1.2.1.25
4.4.1.15
4.6.1.1
D-Cysteine desulfhydrase
Adenylate cyclase
H
2.3.1.41 3-Oxoacyl-[acyl-carrier-protein] synthase HOCH O OOCCH 2CH(NH 3)COO
CEPHALIN CH3COCH 2CH2N(CH 3 )3 CHCOO
Methylmalonyl-CoA OOCCH 2C = CHCOSCoA CH3C = CHCOSCoA (CH3)2CHCH 2COSCoA P-ADP- OCH 2 C(CH 3)2CH(OH)CONHCH 2CH 2CO NHCH 2CH2SH
A
+ 4.6.1.3 3-Dehydroquinate synthase
2.3.1.46 Homoserine O-succinyltransferase
HOCH O CH COO 4.1.3.1 6.4.1.4 1.3.99.10
2.3.1.50 Serine C-palmitoyltransferase
O + CH2OPO CH2CH 2N(CH 3) Acetylcholine CH C(OH)CH
2
CH2COO
ASPARTATE 3-Methyl- 3-Methyl- Isovaleryl-CoA Coenzyme A
4.6.1.4 Chorismate synthase
2.3.1.51 1-Acylglycerol-3-phosphate O-acyltransferase CH2OPO CH2CH2N(CH 3)3 - O 2 CH2OH
OOCCH 2CH2COO 4.2.1.18
M 4.99.1.1 Ferrochelatase
2.1.1.17
- Lysolecithin 3.1.1.5 Glycerophosphocholine 3.1 3
ISOCITRATE 2.7 glutaconyl-CoA crotonyl-CoA
2.3.1.76 Retinol O-fatty-acyltransferase
L CH2OCH=CHR 2.1.1.71 O .4.2 Mevalonate SUCCINATE .2.
4 1.1.1.3
2.4.1.1 Phosphorylase
I R'-CO-OCH O
CH 2 O-CO-R
3.1.1.32
3.1.4.4 2.3.1.6
GTP 6.2.1.4 +
I ISOMERASES
5.1.3.1 Ribulose-phosphate 3-epimerase
CO2
2.4.1.9 Inulosucrase R'-CO-OCH O 2.7.1.36 1.2.1
2 4.1.11 Glycogen (starch) synthase
P
+
CH2OPO CH2CH2N(CH 3)3 +
CH2OPOCH2CH2N(CH 3)3 +
3.1.4.3
+ +
2.7.4.2 1.1.1.41 GDP+Pi 3.1.2.3 .16 P OOCCH 2CH(NH3)COO
Aspartyl-P H H2
+
NH3
N 5.1.3.2
5.1.3.4
UDPglucose 4-epimerase
l-Ribulose-phosphate 4-epimerase
2.4.1.13 Sucrose synthase
-O O - CPP-O CH2CH2N(CH 3)3 P OCH 2CH2 N(CH 3)3 HOCH 2CH2N(CH 3)3 - OOCCH CH COSCoA 1.2 C C
OOCCH 2CH2CONH
O 5.1.3.6 UDPglucuronate 4-epimerase
I
2.4.1.16 Chitin synthase 2.7.7.15 2 2 HC CH 2 H 2C CH2
2.4.1.17 Glucuranosyltransferase Choline LECITHIN CDP-choline Choline-P CHOLINE CH2COO 5-Amino SUCCINYL-CoA
5.1.99.1 .1.
11 + CH-COO
OOCCH 2CH2CONH OOCCHCH 2CH2CH 2CH-COO
+
OOCCH-CH 2CH2CH2CHCOO
+
5.1.3.7 UDP-N-acetylglucosamine 4-epimerase
plasmalogen 1.3.1.35 2.7.8.2 2.7.1.32 OOCC OOCC CH-COO
2.4.1.21 Starch synthase
D 2.7.8
.3
3.1.4.1
2 CH3C(OH)CH 2CH2OPP levulinate 5.4.99.2 OHCCH 2CH (NH3)COO N N OOCCOCH 2CH2CH2CH-COO NH3 NH 3 5.1.3.12 UDPglucuronate 5-epimerase
2.4.1.22
2.4.1.23
Lactose synthase
Sphingosine -galactosyltransferase
S Serine +NH + + + Diphospho- 1.2.4.2
6.3.5.4 Aspartyl
OOCCH 2CH2CHO 4.2.1.52
2, 3-Dihydro- 1.3.1.26
Piperideine- N-Succinyl- 2.6.1.17
N-Succinyl-2, 6 3.5.1.18
Diamino- A 5 1.3.13 dTDP-4-Dehydrorhamnose 3,5-epimerase
5.1.3.14 UDP-N-acetylglucosamine 2-epimerase
2.4.1.29 Cellulose synthase (GDP-forming) 2.3.1.50 3 NH 3 NH 3 NH 3
mevalonate Succinic Semialdehyde dipicolinate 2, 6-dicarboxylate 2-amino-6-oxo- diaminopimelate pimelate C 5.1.99.1 Methylmalonyl-CoA epimerase
CH3(CH2)12CH=CHCH(OH)CHCH 2O- Galactose -OOCCOCH CH COO- 4.1.1.71
2.4.1.32 Glucomannan 4--mannosyltransferase CH 3(CH2)14COCHCH 2OH CH3(CH2)14CH(OH)CHCH 2OH CH3(CH2)12CH=CHCH(OH)CHCH 2OH
2.3.1.37 2 2 semialdehyde pimelate 5.2.1.2 Maleylacetoacetate isomerase
2.4.1.33 Alginate synthase Dehydrosphinganin
1.1.1.102
Sphinganin 4-Sphingenin Psychosine 2-OXOGLUTARATE + +
OH
+ + + + + .7
5.1.1 0
I 5.2.1.3
5.2.1.7
Retinal isomerase
Retinol isomerase
(H3N)(CH2)4 CH(NH 3)COO
D
2.4.1.47 Acylsphingosine galactosyltransferase
2.4.1.62 Ganglioside galactosyltransferase
UDP-Sugars Acyl-CoA 2.4.1.23 Glycine
+
H2NOCCH 2CH (NH3) COO
(CH3)3NCH2CH(OH)CH 2COO (CH3)3N(CH 2)3 CH2CH(NH 3)COO (CH3)3N(CH 2)3 CH2CH(NH 3)COO
4.1.1
.2 5.3.1.1 Triose-phosphate isomerase
Gangliosides 2.4.1.62 3.5.1.23 Acyl-CoA 4.1.1.33 Carnitine N -Trimethyl-
6
N -Trimethyllysine
6
LYSINE 1.5.1.7 - 10
S
5.3.1.3 Arabinose isomerase
2.4.1.68 Glycoprotein 6-a-l-fucosyltransferase
UDP-Galactose Asparagine 1.14.11.1 1.14.11.8
3-OH-lysine 5.3.1.4 l-Arabinose isomerase
NADH+H +
2.4.1.69 Galactoside 2-a-l-fucosyltransferase
NHAcyl O NHCOR
2.4.2.1 Purine-nucleoside phosphorylase + NHCOR 2.6.1.19 COO 5.3.1.5 Xylose isomerase
+
CH3(CH2)12CH=CHCH(OH)CHCH 2O PO CH2CH2N(CH 3)3 CH3(CH2)12CH=CHCH(OH)CHCH 2O- Galactose R-CH(NH3) COO 5.3.1.6 Ribose-5-phosphate isomerase
2.4.2.2 Pyrimidine-nucleoside phosphorylase
O - CH3(CH2)12CH=CHCH(OH)CHCH 2OH CH2
+ +
NH CHCH 2CH2COO
+ 5.3.1.8 Mannose-6-phosphate isomerase
2.4.2.4
2.4.2.8
Thymidine phosphorylase
Hypoxanthine phosphoribosyltransferase SPHINGOMYELIN
2.7.8.3
Ceramide 3.2.1.46 2.4.1.47 Cerebroside CH3C-CH2CH2OPP 2-AMINO ACID 1.3.99.7 OOCCH 2CH 2CH2COSCoA OOCCH 2CH2CH2COCOO OOCCH 2CH2CH2CH (NH3) COO OHCCH 2CH2CH2CH (NH3) COO CH 2CH2CH2CH2CH (NH3) COO 5.3.1.9 Glucose-6-phosphate isomerase
3.1.4.12
2.4.2.9 Uracil phosphoribosyltransferase
1.3.99.7 Isopentenyl-PP 2.6.1.- 4.1.1.70
Glutaryl-CoA 2-Oxoadipate 2.6.1.39
2-Aminoadipate 1.2.1.31 2-Aminoadipate 1.5.1.9
Saccharopine 5.3.1.16 N-(5-Phospho-d-ribosylformimino)-
2.4.2.10 Orotate phosphoribosyltransferase CH3
(C5) NAD + TR R-CO-COO OOCCH 2CH2CH2NH2 semialdehyde 5-amino-1-(5-phosphoribosyl)-
4-imidazolecarboxamide isomerase
2.4.2.11 Nicotinate phosphoribosyltransferase
2.4.2.14 Amidophosphoribosyltransferase I CH3C = CHCH 2OPP I
1.6.5.3
FMN AN
SA 2-OXO ACID 4-Aminobutyrate Adenosyl 5.3.3.2 Isopentenyl-diphosphate -isomerase
Lycopene (C40) Phytoene Dimethylallyl-PP MI (GABA) CH3-SCH 2CH2CHNH 2
S
2.4.2.15 Guanosine phosphorylase 5.3.99.3 Prostaglandin-E synthase
Fe--S N H2N(CH 2)3NH(CH2)4NH (CH2)3NH2
2.4.2.17 ATP phosphoribosyltransferase (C40) (C5) FMNH 2 AT + 5.3.99.5 Thromboxane-A synthase
To Brain - VISION 2.5.1.1 IO Spermine S-Adenosylmethyl L E G E N D
2.4.2.18
2.4.2.19
Anthranilate phosphoribosyltransferase
Nicotinate-nucleotide pyrophosphorylase O hv CH3
2e- +
2H+ N +
.1 . 15 thiopropylamine
5.4.2.1
5.4.2.2
Phosphoglycerate mutase
Phosphoglucomutase
CH 3
4H +
4H OOCCH 2CH 2CH (NH3) COO 4.1 Carbohydrates
(carboxylating)
P -CAROTENE (C40) 2.5.1.32 2.5.1.29 CH3C= CHCH 2 CH2C= CHCH 2OPP
(Decarboxylated SAM)
Biosynthesis Degradation
5.4.2.3 Phosphoacetylglucosamine mutase

GLUTAMATE
5.4.2.8 Phosphomannomutase
Mitochondrial Intermembrane Space

2.4.99.1-11 Sialyltransferases
2.4.99.7 Sialyltransferase R Metarhodopsin Rhodopsin CH2OPP Geranyl-PP 2H+ 2.7.2
2.5.1.22 5.4.3.8 Glutamate-1-semialdehyde 2,1-aminomutase
O _ .11 +
Mitochondrial Outer Membrane

Amino Acids
Mitochondrial Inner Membrane

2.5.1.1 Dimethylallyltranstransferase (C10) POOCCH2CH 2CH(NH3) COO 5.4.99.2 Methylmalonyl-CoA mutase

2.5.1.6 Methionine adenosyltransferase E 1.13.11.21
COO- Opsin
CH3O CH3
Geranyl-geranyl-PP II
SUCCINATE NO3 1.4.1.2 1.4.1.14 3.5.1.2 Glutamyl-P
H2N(CH 2)4NH (CH2)3NH2
Biosynthesis Degradation
5.4.99.5 Chorismate mutase
2.5.1.10 Geranyltranstransferase
N
CH3O n (C20) UQ
1.3.5.1 Fe--S FAD 6.3.1.2 Spermidine 5.4 99.7 Lanosterol synthase
2.5.1.16 Spermidine synthase
Retinoate
O Ubiquinone 2.5.1.10 UQH2
FUMARATE
1.6.6.1
Lipids
5.5.1.4 myo-Inositol- l-phosphate synthase
2.5.1.19
2.5.1.21
3-Phosphoshikimate 1-carboxyvinyl-transferase
Farnesyltransferase O 1.2.1.36
CHO (Coenzyme Q) OPP
2H+ 2H+
1.7.99.4 3.5.1.2
1.2.1.41 Biosynthesis Degradation LIGASES
_
NH+
2.5.1.16
2.5.1.22 Spermine synthase
I trans-Retinal 5.2.1.3
11-cis-Retinal CHO Menaquinone CH2OH CH2 1.7.7.1 6.2.1.3 Long-chain-fatty-acid-CoA ligase
2.5.1.29
2.5.1.32
Farnesyltranstransferase
Geranylgeranyl-diphosphate geranylgeranyl D
Light Phytol (C20) NO2 1.6.6.4
4 +
H2NOCCH 2CH2CH (NH3) COO + H2NCH2CH2CH2CH2NH2
Purines & Pyrimidines 6.3.1.1
6.3.1.2
Aspartateammonia ligase
Glutamateammonia ligase
Retinol esters 1.1.1.105 1.1.1.105 Plastoquinone OHCCH 2CH 2CH(NH3) COO Biosynthesis Degradation
transferase
S CH3 III 1.10.2.2 .1 Glutamine Putrescine 6.3.1.4 Aspartateammonia ligase (ADP-forming)
2.6.1.- Transaminases
Farnesyl-PP 8.6 ATP Glutamic 6.3.1.5 NAD+ synthetase
2.6.1.1 Aspartate transaminase
O HO CH 3 Fe-S and 2e- 1 .1 Vitamins, Co-Enzymes & Hormones 6.3.2.1 Pantoate-alannine ligase
2.3.1.76 (C15) Cytochromes 6.3.4.16 CO2 semialdehyde
2.6 1.2
2.6.1.4
Alanine transaminase
Glycine transaminase 3.1.1.21
CH2OH
5.2.1.7
CH2OH
CH 3 O
CH3 2H+ 2H+
MITOCHONDRIAL
MATRIX N2 6.3.5.5 CH2 CH2
CH3COCOO OHCCOO
6.3.2.2
6.3.2.3
Glutamatecysteine ligase
Glutathione synthase
2.6 1.5 Tyrosine transaminase trans-Retinol 11-cis-Retinol O
Phylloquinone -Tocopherol Pyruvate Glyoxylate Pentose Phosphate Pathway 6.3.2.5 Phosphopantothenatecysteine ligase
2.6 1.6 Leucine transaminase S (Vitamin A) Dark (Vitamin K) (Vitamin E)
2.5.1.21
CH CHCOO 6.3.2.6 Phosphoribosylaminoimidazole-
2.6.1.9 Histidinol-phosphate transaminase
T Cyt.c H2NCOOP 2.6.1.13 N
succinocarboxamide synthase
2.6.1.13 Ornithineoxo-acid transaminase STEROIDS Carbamoyl-P + Photosynthesis Dark Reactions 6.3.2.7 UDP-N-Acetylmuramoyl-l-alanyl-
2H+ H 2NCONHCH 2CH2CH2CH(NH3) COO Pyrroline-5-
E IV
2.6.1.16 Glutaminefructose-6-phosphate transaminase d-glutamatelysine ligase
1.9.3.1 4.1.3.16
2.6.1.17 Succinyldiaminopimelate transaminase
Cu and H2O CITRULLINE carboxylate 6.3.2.8 UDP-N-acetylmuramatealanine ligase
2.6.1.18
2.6.1.19
-Alaninepyruvate transaminase
4-Aminobutyrate transaminase
R Progesterone Cytochromes 2.1.3.3 4.1.1.17
OOCCH(OH)CH 2COCOO
Human Metabolism is identified as far as possible by black arrows
Biosynthesis Degradation
6.3.2.9 UDP-N-acetylmuramoylalanine
d-glutamate ligase
2.6.1.22 l-3-Aminoisobutyrate transaminase O H
HO
H
HO
H 2H+ 2H+ 3H + 1.5.99.8
CH2 CH2
4-Hydroxy- 6.3.2.10 UDP-N-acetylmuramoylalanyl-
HO
2.6.1.23 4-Hydroxyglutamate transaminase HO 1.5.1.2 2-oxoglutarate Small numbers refer to the IUBMB Enzyme Commission d-glutamyl-lysined-alanyl-d-alanine ligase
2.6.1.27 Tryptophan transaminase I Pregnenolone CHOLESTEROL Desmosterol
H
Zymosterol
H
Lanosterol 5.4.99.7
Squalene Pi +
H2NCH2CH2CH2CH (NH3) COO
CH2 CHCOO Reference Numbers for Enzymes
6.3.2.13 UDP-N-Acetyl muramoylalanyl-d-
M I TO

glutamate2,6-diaminopimelate ligase
D
2.6.1.32 Valine3-methyl-2-oxovalerate transaminase
1.14.99.7 (C30)
2.6.1.36 l-Lysine 6-transaminase
COO-
ADP ORNITHINE
NH
2.6.1.23 COMPARTMENTATION
6.3.3.1 Phosphoribosylglycinamidine cyclo-ligase

S COO- 3.6.1.34 6.3.4.5

PROLINE 6.3.4.1 GMP synthase
CH

2.6.1.39 2-Aminoadipate transaminase The "BACKBONE" of metabolism involves GLYCOLYSIS, the TCA CYCLE
1H+
TRA N SLO

2.6.1.42 Branched-chain-amino-acid transaminase

COO- ATP and OXIDATIVE PHOSPHORYLATION. It is a major source of energy (ATP)
6.3.4.2 CTP synthase
ON

CH2 CH2 CH2 +

2.6.1.44 Alanine-glyoxylate transaminase CHLOROPHYLL COO- CH2
COO- 1.14.11.2 6.3.4.3 Formatetetrahydrofolate ligase
OOCCH(OH)CH 2CH(NH 3)COO and is the origin and termination of most of the pathways. GLYCOLYSIS
DR

OOCCHCH 2COO
2.6.1.51 Serinepyruvate transaminase
P CH H
CH3
CH2
CH H2 CH3 CH CH2 H2 CH3
CH2 -OOC CH2 H CH2 -OOCCH CH COCH NH
2 2 2 2
H2NCONH 2
4-Hydroxy- occurs in the CYTOPLASM. The TCA CYCLE is in the MITOCHONDRIAL
6.3.4.4 Adenylosuccinate synthase
IA

CH2
2.6.1.52 Phosphoserine transaminase C C 2
C C
2
5-Amino N 2.1.4.1 UREA N + 6.3.4.5 Argininosuccinate synthase
L

HOCH CH2 MATRIX. OXIDATIVE PHOSPHORYLATION (ATP SYNTHESIS) spans the

O H3 C CH H3 C CH NE glutamate 6.3.4.7 Ribose-5-phosphateammonia ligase
I

2.6.1.66 Valinepyruvate transaminase H3 C CH2 H 2C CH2 H2NCNHCH 2CH 2CH2CH(NH3) COO

2.7.1.1 Hexokinase N N N N N N N levulinate R
ME Glycine + Arginino- H2C CHCOO MITOCHONDRIAL INNER MEMBRANE. This last part has been redesigned 6.3.4.13 Phosphoribosylamineglycine ligase
R H H H H H H
N
COO- MB 3.6.1.3 3.5.3.1 3.5.3.6
NO N CH2 to illustrate the activation of ATP-synthase and formation of ATP - driven by 6.3.4.16 Carbamoyl-phosphate synthase (ammonia)
CAT

2.7.1.2 Glucokinase HOCH

RAN
HC Fe CH H2 C CH2 H2 C CH2 H 2C CH2 E NH2 succinate H 1.5.1.12 the electromotive translocation of protons across the mitochondrial inner 6.3.4.17 Formatedihydrofolate ligase
P
2.7.1.3 Ketohexokinase
H H H H -OOC + HC CHCOO membrane. A similar compartmentation occurs in the chloroplast, where
2.7.1.4 Fructokinase HEMOGLOBIN N N N N N N H H CH2 H2NCNHCH 2CH2CH2CH (NH3) COO 1.14.13.39 6.3.5.1 NAD+ synthetase (glutamine-hydrolysing)
N N
HYDROXY
ED

N light-driven proton translocation across the inner thylakoid membrane

H
2.7.1.6 Galactokinase 6.3.5.2 GMP synthetase (glutamine-hydrolysing)
H3 C CH3 H3 C CH3 H3 C CH3 H 2C CH2 CH2 3-Hydroxy-
2.7.1.7 Mannokinase C C C - C
H2 C
RO ARGININE PROLINE
initiates synthesis of the ATP necessary for Photosynthesis. In both 6.3.5.3 Phosphoribosylformylglycinamidine synthetase
P

COO-
2.7.1.11 6-Phosphofructokinase
Y CH2
H CH2 CH2 H2 CH2 CH2 H2 CH2 OOC CH2 H2 CH2
4.2.1.24
TO pyrroline- cases flow of electrons and protons is shown in red or blue arrows 6.3.5.4
6.3.5.5
Asparagine synthase (glutamine-hydrolysing)
Carbamoyl-phosphate synthase
H2 C N N 1H+ 4.3.2.1 5-carboxylate
R CH2
COO-
CH2
COO-
CH2
COO-
CH2
COO-
CH2
COO-
CH2
COO-
CH2
COO-
CH2
COO- H2 N
H S
+ + NH + NH2 HN C
NH CO Electron Flow Proton Flow 6.4.1.1
(glutamine-hydrolysing)
Pyruvate carboxylase
I 1.3.3.3 4.3.1.8
3H 2
+ NH2
N CH 2 6.4.1.2 Acetyl-CoA carboxylase
HEME 1.3.3.4
Protoporphyrinogen Coproporphyrinogen 4.1.1.37Uroporphyrinogen 4.2.1.75 Porphobilinogen ADP Pi
H2NCNHCH 2COO H2NCN(CH 3)CH2COO P- HNCN(CH 3)CH2COO 1.5.1.2 6.4.1.3 Propionyl-CoA carboxylase
N 4.99.1.1 2.1.1.2 CH3 Some other pathways occurring in the mitochondria
ATP
2.7.3.2 P-Creatine
IX III III Guanidoacetate Creatine Creatinine are identified by a pale yellow background
6.4.1.4 Methylcrotonoyl-CoA carboxylase

S 3.5.2.10

Cytoplasm
Cytoplasmic Membrane