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Electromagnetic spectrum
short wavelengths
long wavelengths
High-energy
photons
Low-energy
Gamma X-rays Visible photons
Terminology
X-Ray Source
Detector/
film
• Transmission Patient
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Medical Image Formation
Attenuation processes
• Compton interaction
• Photo-electric absorption
Fundamental law of
attenuation
• Equal thicknesses of absorber transmit equal
fractions (percentages)
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Medical Image Formation
Patient dose
Patient dose
• Entry dose
– 10 times higher for anteroposterior chest
– 100 times for anteroposterior abdomen or skull
– 1000! times for a lateral pelvis
Image Sciences institute / University Medical Center Utrecht
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Medical Image Formation
• Increasing focus-film
distance: increases
body surface exposed
and thereby lowers
the skin dose
• Charge (mAs) has to
increase to
compensate for longer
distance
Subject contrast
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Medical Image Formation
Spatial resolution
Matrix
256x256
128x128
64x64
• Pixel size and
amount of
blurring
determine
sharpness of the
image
FOV
• (NOTE: example
image is MRI
image!)
Contrast I ( x ) = I 0 ⋅ e − µx
• Determined by C ∝ ( µ1 − µ 2 ) ⋅ t
– Thickness of structures
– Difference in linear attenuation coefficients µ1 and µ2
bone
t µ1 µbot2
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Medical Image Formation
• Due to different
attenuations of τ∝ρ
Z3
materials E3
• Shortcoming: little
contrast between
various soft tissues
• Contrast media ρ
σ∝
– K-edge (photoelectric E
absorption)
• Barium
• Iodine
Scattered radiation
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Medical Image Formation
grid
Scatter reduction
after beam has left the patient
• Air gap
– Slightly decreases primary radiation
– Strongly decreases secondary radiation
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Medical Image Formation
fluorescent
screen #2
Film
fluorescent
screen #1
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Medical Image Formation
Screen-film cassette
Properties of film/screen
assembly
X-ray absorption in
fluorescent screens
fluorescent
screen
Blurred pattern
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Medical Image Formation
Scattered radiation
d/2
Image Sciences institute / University Medical Center Utrecht
10
Medical Image Formation
X-ray film
X-rays
Absorption
film
Optical density
I0
film
O.D. I0/I
0 1
O.D.=log(I0/I) .3 2
I 1 10
2 100
3 1000
Density
slope = γ
shoulder
toe
base + fog
Log (E)
Image Sciences institute / University Medical Center Utrecht
11
Medical Image Formation
Film properties
Current applications
• Plain radiography
• Mammography
• DSA = Digital Subtraction Angiography
• CT = Computer Tomography
• CTA = CT Angiography
• RX(A) = Rotational X-ray (Angiography)
Plain radiography
Fractures
Thorax (TBC)
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Medical Image Formation
• Fast
• Not expensive
Mammography
Visualizing
microcalcifications
(0.1 mm) with high
contrast
Mammography
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Medical Image Formation
Fluoroscopy
Image intensifier
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Medical Image Formation
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