Professional Documents
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F acial
distribution
numbness
of the mental
localized to
nerve-
the thesia,
destruction.
pain, local swelling, and bone important anatomic
are the relationship
features
of each
displayed
tooth
in this
to the mandibular
plane
mental nerve neuritis or mental canal, the buccal and lingual cortical margins of the
mandible, and the spongiosa between these cortices.
nerve neuropathy-has been labelled the
Materials and Methods Figure 1 shows the normal anatomy of the man-
numb chin syndrome. The inferior alveolar
dibular, inferior alveolar. and mental nerves.
nerve may also be involved. This uncom- We present I 5 causes of the numb chin syndrome
mon neuropathy is almost always unilateral, in I 5 patients. These cases were evaluated by CT
with anesthesia or hypoesthesia of the chin scans of the mandible in axial, panoramic. and buc-
colingual planes. Nine of the patients were female,
Causes
and lower lip found on physical examina-
six were male. and they ranged in age from 7 to 79 The causes of this syndrome can be
tion. When not associated with iatrogenic
years old.
local anesthesia, the condition is most corn- grouped into several categories. Dental causes
CT imaging of the mandible was performed on
monly due to dental diseases. In the absence are by far the most common. They may be iat-
Elite 2400 CT scanners (Elscint, Haifa, Israel) using
of these causes. the condition is clinically dedicated software for dental imaging (Denta CT,
rogenic (following anesthesia or as a compli-
significant because of its frequent associa- Elscint). Thin-section overlapping axial cuts ( I .2- cation of a dental procedure) (Fig. 2); due to
tion with malignant diseases [1-4). In some mm sections at 1.0-mm intervals) were acquired at pressure from an ill-fitting denture in an eden-
cases the numb chin syndrome may even be I 20 kVp and 165 mAs parallel to the alveolar pro- tulous atrophic mandible in an elderly person
the presenting symptom of an unsuspected cess of the mandible. These axial scans formed the (Fig. 3); or associated with infection of the
malignancy: more frequently it heralds a scaffold for generating reformatted panoramic and root of a tooth (Fig. 4), acute or chronic osteo-
cross-sectional (buccolingual) images using the myelitis of the mandible (Figs. 4 and 5), or
relapse in a patient with a known neoplasm
Denta CT software.
[1]. In such cases this finding, despite its odontogenic or nonodontogenic tumors or
The direct-CT axial images and the reformatted-
seemingly clinically benign symptoms, is cysts of the mandible (Figs. 6-8).
CT panoramic views show the mandibular canal
ominous because it usually implies a grave Second to dental causes are neoplasms,
partially or in its entire horizontal length, depending
prognosis [2, 4]. Although painless mental on the section obtained. The reformatted buccolin-
malignant much more commonly than benign,
nerve neuropathy may be the only symptom gual images uniquely show the cross-sectional anat- and metastatic much more commonly than pri-
of distant malignant disease, mandibular omy of the mandibular canal, including the mental mary. Any type of malignancy can metastasize
metastases may be accompanied by pares- foramen on the buccal side of the mandible. Other to the mandible; however, by far the most fre-
I
,.
B
Fig. 2.-41-year-old man with retained tooth remnant as complication of dental procedure.
A, CT scan in panoramic plane reveals cavity (long arrow) of extracted tooth, with remnant of root (short arrow) lying in mandibular canal (arrowhead).
B, CT scan in axial plane shows tooth remnant (short arrow) in mandibular canal (arrowhead).
C, CT scan in buccolingual plane shows fragment of tooth (short arrow) in mandibular canal (arrowhead).
quent is carcinoma of the breast (Figs. 9 and mandible of a primary squamous cell carci- (Fig. 15) and benign and malignant nerve
10). The numb chin syndrome has been noma of the lower lip (Fig. 12). Other associ- sheath tumors (Fig. 16)]. Leptomeningeal car-
reported in primary carcinomas of the lung, ated neoplasms include acute lymphocytic cinomatosis and tumors involving the base of
thyroid, kidney, prostate, and nasopharynx and leukemia, Hodgkin’s and non-Hodgkin’s lym- skull have been implicated in a small percent-
also in melanoma. The syndrome can occur phoma (Fig. 13), myeloma (Fig. 14), and age of patients. Malignant cells are usually
with primary osteosarcoma of the mandible tumors of the inferior alveolar nerves and found in the CSF in such patients.
(Fig. 11) and from direct extension into the mental nerves and their sheaths [neurofibroma Trauma, through fracture of the ramus or
Fig. 3.-Pressure trauma of dentures on exposed mandibular canal as result of resorption of alveolar bone in edentulous 71-year-old man.
A, CT scan in panoramic plane reveals resorption of alveolar bony ridge of right side of mandible (arrow). Loss of bone height progresses significantly from posterior to
anterior.
B, CT scan in buccolingual plane at level of posterior body of mandible shows mild loss of height of alveolar bony ridge (arrow) relative to mandibular canal (arrowhead).
C, CT scan in buccolingual plane at level of mid anterior body of mandible shows severe loss of height of alveolar bone (arrow), with unroofing of mandibular canal
(arrowhead) exposing inferior alveolar nerve.
body of the mandible, is a third cause of the been reported in some patients and is attrib-
syndrome. uted to a viral inflammation analogous to other
A fourth cause is systemic disease such as transient cranial mononeuropathies, such as
sickle cell anemia, multiple sclerosis, amyloi- Bell’s palsy. Careful follow-up of such
dosis, sarcoidosis, and diabetes mellitus. patients is, however, necessary before the
Spontaneous remission of symptoms has
Fig. 8.-Hemangioma in 7-year-old boy who needed two units of blood following extraction of tooth.
A, CT scan in panoramic plane shows expanding lytic lesion (arrow) thinning bony margins of mandible and involving mandibular canal (arrowhead). Lesion enhanced
markedly after injection of contrast material during other studies (not shown).
B, CT scan in buccolingual plane reveals ballooning of cortical margins by large lytic lesion that has eroded through roof of mandibular canal (arrowhead). Canal has en-
larged considerably.
A B
dibular canal, and the plexiform arrangement malignancies such as squamous cell carci- References
of the inferior alveolar nerve [5]. Some have noma of the lip, lymphoma, melanoma, and
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1281
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3. Barrett AP. Selective anesthesia of the inferior alve-
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Surg Oral Med Oral Patliol 1990:69:299-306
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is an important pathway for spread of certain cranial nerves. Oral Pathol 1979:48:509-5 12