1. Which of the following is the primary site of activity for the drug Warfarin?

A. Kidney
B. Liver
C. Blood
D. Heart

2. Which of the following drugs is associated with the reaction of hepatitis?

A. Valproic acid
B. Quinidine
C. Isoniazid
D. Ethosuximide

3. A drug ending in the suffix (pril) is considered a ______.

A. H
B. ACE inhibitor
C. Antifungal
D. Beta agonist

4. A drug ending in the suffix (azole) is considered a ______.

A. H
B. ACE inhibitor
C. Antifungal
D. Beta agonist

5. A drug ending in the suffix (tidine) is considered a ______.

A. Antidepressant
B. Protease inhibitor
C. Beta antagonist
D. H2 antagonist

6. A drug ending in the suffix (navir) is considered a ______.

A. Antidepressant
B. Protease inhibitor
C. Beta antagonist
D. H2 antagonist

7. Which of the following drugs is associated with the reaction of extreme photosensitivity?

A. Digitalis
B. Niacin
C. Tetracycline
D. Fluoroquinolones

8. Which of the following is not related to a drug toxicity of Prednisone?

A. Cataracts
B. Hypotension
C. Psychosis
D. Acne

9. Which of the following is considered a class IA Sodium Channel blocker?

A. Mexiletine
B. Aminodarone
C. Quinidine
D. Procainamide

10. Which of the following is considered a class IA Sodium Channel blocker?

A. Propafenone
B. Disopyramide
C. Aminodarone
D. Quinidine

11. Potassium sparing diuretics have the primary effect upon the _____ found in the kidney.

A. Proximal convoluted tubule

B. Loop of Henle
C. Collecting duct
D. Distal convoluted tubule

12. Which of the following is not directly related to a drug toxicity of Nitroglycerin?

A. Headaches
B. Tachycardia
C. Dizziness
D. Projectile vomiting

Answer Key
1. B
2. C
3. B
4. C
5. D
6. B
7. C
8. B
9. B
10. A
11. D
12. D

1. Which of the following is not a side effect of the Ace Inhibitor (Captopril)?

A. Rash
B. Angioedema
C. Cough
D. Congestion

2. Which of the following is not a side effect of the Vasodilator (Nifedipine)?

A. Nausea
B. Flush appearance
C. Vertigo
D. Sexual dysfunction

3. Which of the following is not a side effect of the Sympathoplegics (Clonidine)?

A. Hypertension
B. Asthma
C. Dry oral cavity
D. Lethargic behavior

4. Which of the following is not a side effect of the Dieuretics (Loop dieuretics)?

A. Alkalosis
B. Nausea
C. Hypotension
D. Potassium deficits

5. Which of the following is not an effect of the drug (Clozapine)?

A. Agranulocytosis
B. Antipsychotic
C. Used for Schizophrenia
D. Increased appetite

6. Which of the following is not treated with (Epinephrine)?

A. Renal disease
B. Asthma
C. Hypotension
D. Glaucoma

7. Which of the following is not treated with (Ephedrine)?

A. COPD
B. Hypotension
C. Congestion
D. Incontinence

8. Which of the following are not treated with Barbiturates?

A. Seizures
B. Hypotension
C. Insomnia
D. Anxiety

9. Which of the following are not treated with Nifedipine?

A. Angina
B. Arrhythmias
C. Htn
D. Fluid retention

10. Which of the following are not treated with Methotrexate?

A. Sarcomas
B. Leukemias
C. Ectopic pregnancy
D. Rheumatic fever

11. Which of the following are not treated with Prednisone?

A. Cushing's disease
B. Testicular cancer
C. Lympthomas
D. Chronic leukemias

12. Which of the following are not treated with Dexamethasone?

A. Inflammation
B. Asthma
C. Addison's disease
D. Wilson's disease
Answer Key
1. D
2. D
3. B
4. B
5. D
6. A
7. A
8. B
9. D
10. D
11. B
12. D

1. Which of the following cannot be refilled under any circumstances?

a. Metoprolol
b. Methylphenidate
c. Mitomycin
d. Hydroxyurea

2. Valproic acid syrup is available as 250 mg/5 cc. If a patient is taking 1000 mg in the
morning and 750 mg in the evening, how many cc of syrup will you dispense for a 30 day
supply ?

a. 1500 cc
b. 1050 cc
c. 500 cc
d. 480 cc

3. If a patient was taking Glyburide for type II diabetes and a physician prescribed
Chlorpropamide, the pharmacy technician will :

a. Fill the prescription.

b. Notify the pharmacist about duplication of therapy.
c. Notify the pharmacist about any interaction.
d. All of the above.

4. All of the following drugs should be carefully prescribed with aspirin EXCEPT

a. Enoxaprine
b. Coumadin
c. Heparin
d. Metoclopropamide

5. Overdose of Coumadin can be treated by

a. Vitamin K
b. Acetylcysteine
c. Mesna
d. Protamine sulfate

6. Prochlorperazine can be classified as a

a. Antiemetic
b. Antidepressant
c. Anti-anxiety
d. Antihypertensive

7. A patient is taking Amoxicillin 500 mg by mouth three times a day for 7 days. How many
capsules of 500 mg of Amoxicillin will you dispense?

a. 42
b. 21
c. 7
d. 30

8. The cost of 100 tablets of Olanzapine is $420.00. The percentage mark up on the
prescription is 15%. What would be the retail cost of 30 tablets of the above drug ?

a. $200
b. $145
c. $300
d. $450

9. How much quantity of 3% salicylic acid powder is required to mix with talc powder to
make 0.20% of 500 gram of Salicylic acid ?

a. 50 gm
b. 33 gm
c. 480 gm
d. 57 gm

10. Clopidrogel is classified as a :

a. Anti-hypertensive.
b. Platelet aggregation inhibitor.
c. Anti-diabetic.
d. Anti-Parkinson’s.

11. All of the following drugs can be indicated for the treatment of asthma EXCEPT

a. Ipratropium
b. Metoprolol
c. Albuterol
d. Zafirlukast

12. A prescription for MS Contin 30 mg was written as follows:

Manan Care Rx
Mr. Shroff 1/1/01

Ms Contin 30 mg
sig- 1 po tid x 30 day

# 60
Dr. Bhatia 1/1/02
Refill-0 MHS
DEA # AB2354760

What would be the dispense quantity for the above prescription ?

a. 90
b. 60
c. 30
d. 10

13. Mr. X brings a prescription for Diazepam 10 mg to your pharmacy. Upon reviewing the
profile, the prescription has already been refilled 5 times. The pharmacy technician will :

a. Refill the prescription as it was written prn times.

b. Cannot refill. Notify the pharmacist.
c. Refuse to fill since prescription needs DEA form 222.
d. Refuse to fill since strength is unavailable.

14. Which of the following auxiliary labels is required when dispensing Otocort otic
solution ?

a. Take with food.

b. Do not consume alcoholic beverages.
c. For ear only.
d. Shake well before dispensing.

15. All of the following drugs are colony and erythrocytes stimulators EXCEPT

a. Filgrastim.
b. Epotein.
c. Tamsulosin.
d. Sargramostim.

16. Lanoxin pediatric solution is available in 0.05 mg/ml. If patient is taking 0.25 mg of
Lanoxin per day, what would be the dispense quantity in mls for 30 days ?

a. 25 cc
b. 50 cc
c. 100 cc
d. 150 cc

1 (b) Methylphenidate is a controlled class II drug. It is indicated for treatment of attention

deficit hyperactivity disorder (ADHD). It cannot be refilled under any circumstances.
2 (b) 1050cc. In this type of calculation first find out number of cc required for 1 day.

Morning dose

Drug ml of solution
250 mg present 5 cc of solution
1000 mg ?

1000 x 5cc / 250 = 20 cc of solution.

Evening dose

Drug ml of solution
250 mg present in 5 cc of solution
750 mg ?

750 x 5cc / 250 = 15 cc of solution.

For a 30 day supply of Valproic acid

(20 cc (am) + 15 cc (pm) ) x 30 = 1050cc.

3 (b) Glyburide and Chlorpropamide are oral sulfonylurea agents indicated for treatment of
diabetes. Pharmacy technician will notify the pharmacist about duplication of therapy.

4 (d) Aspirin is a blood thinning agent indicated for prevention of heart stroke. It should be
carefully prescribed with other blood thinning agents
because of risks of bleeding. Lovenox (Enoxaprine), Coumadin (Warfarin), Heparin, Plavix
(Clopidrogel), Ticlid (Ticlopidine), Depakene (Valproic acid), Persantine (Dipyridamole),
Mandol (Cefamandole), Cefotan (Cefotetan), Cefobid (Cefoperazone) and Moxam
(Moxalactam) are agents that increase bleeding tendency in patients and should be carefully
prescribed with other blood thinning agents.

5 (a) The overdose of Coumadin can be treated by administration of Vitamin K1

(Mephyton).

6 (a) Compazine (Prochlorperazine) is indicated for treatment of nausea and vomiting and
therefore is classified as an anti-emetic (agent that prevent nausea and vomiting).

7 (b)

8 (b) The cost of 100 tablets of Olanzapine is $420 and therefore the cost of one tablet of
Olanzapine would be $420/100 = $ 4.20.

The % mark-up on the prescription is 15%

Cost of prescription mark up on rx

$ 100 $ 15
$ 4.20 ?
15 x 4.20 / 100 = $ 0.63, therefore dispensing cost of each prescription would be
$ 4.20 + $ 0.63 = $ 4.83

The cost of 30 tablets would be $ 4.83 x 30 = $145

9 (b) 33 grams. For calculations of this type the allegation method is very useful. We want
to prepare 500 gm of 0.2 % salicylic acid by mixing talc (0 %) powder with 3 % of Salicylic
acid powder.

3 % salicy 0.2 (3 % sali)

0.2 %

0 % talc (no salicy) 2.8 (0% sali)

Total 3.0 (0.2 % sali)

We want to find out how many grams of 3 % salicylic acid required

Total parts of 0.2% sali Parts of 3 % sali

3 parts 0.2 parts 500 ?

500 x 0.2 / 3 = 33 grams of 3% salicylic acid required.

10 (b) Plavix (Clopidrogel) is a blood thinning agent. Agents of this class generally act by
inhibiting aggregation of platelets which is thought to be the primary mechanism of blood
clotting. It is indicated for prevention of heart stroke in patients with CHF.

11 (b) Asthma is characterized by increased responsiveness of trachea and bronchi to

various stimuli and narrowing of airways. It is associated with shortness of breath, chest
tightness, wheezing and coughing. The Beta-2 receptors stimulation generally dilates the
bronchial smooth muscles and helps in controlling asthma.

Beta-2 receptors blockers generally constrict the smooth muscles of bronchi and may even
aggregate asthma.

Metoprolol is a Beta-1 and Beta-2 receptor blockers indicated for treatment of hypertension
and should be carefully prescribed in patient with asthma. Other choices such as Accolate
and Atrovent are indicated for treatment of asthma.

12 (b) The prescription of CII controlled drugs should be dispensed with specific quantity
mentioned on prescription by physician. MS-contin is a controlled II drug and therefore
correct dispensing quantity would be 60.

13 (b) Prescription of controlled drugs III, IV and V cannot be refilled more than 5 times. A
patient must bring a new prescription after this allowable refill is executed. Prescriptions
older than 6 months require a new prescription to fill.

14 (c) Otocort otic solution is intended for ear use only. It should not be applied to eyes and
therefore the auxiliary label “ For ear use only” is required.
15 (c) Tamsulosin is the generic name of Flomax. It is indicated for treatment of B.P.H. All
of the rest of the choices are colony stimulator agents. They generally help in stimulation of
erythrocyte and granulocytes.

16 (d) 150 cc. Lanoxin is available in 0.05 mg/ml. Patient is taking 0.25 mg per day.

Drug ml of solution
0.05 mg 1 ml
0.25 mg ?

0.25 x 1 / 0.05 = 5ml

for 30 days supply = 30 x 5cc = 150cc