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"Methodological Issues and Strategies in Clinical Research, Third Edition

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 Vol. 3, No. 6, June 2007 “Can You Handle the Truth?”

“Methodological Issues and Strategies in Clinical Research, Third

Edition”
Alan E. Kazdin, Editor, 2002, 913 pages, American Psychological Association,
$59.95
Review by Norman M. Goldfarb

“Methodological Issues and Strategies in Clinical Research, Third Edition” includes 39 essays
by 65 contributors, organized in nine sections:
• Introduction: Overview and Background
• Beginning the Research Process
• Methods: Principles and Practices
• Assessment
• Data Analysis, Evaluation, and Interpretation
• Special Topics in Clinical Research
• Ethics in Research
• Publication and Communication of Research
• Perspectives on Methodology
The book is entirely about
psychological research, a very
welcome compilation and no This book has been selected for
doubt a great comfort to The First Clinical Research Bookshelf
psychological researchers Essential reading for clinical research professionals
troubled by identity anxiety
because of the dominance of drug intervention in books about clinical research.
Researchers dependent on drugs for their livelihood will find some chapters of interest. For
example, quality-of-life measures often have psychological components. With depressed or
attentionally-challenged patients, psychological research methodologies can hone in on key
behavioral and pharmacological measures of change, while minimizing expectancy effects,
assessment bias, selection bias, and other corrupting factors. The data analysis section
includes interesting material about statistical significance, power, null hypotheses, and
Bayesian analysis.
The book is available at bookstores.

Reviewer
Norman M. Goldfarb is Managing Director of First Clinical Research LLC, a provider of clinical
research best practices information, consulting and training services. Contact him at
1.650.465.0119 or ngoldfarb@firstclinical.com.

Subscribe free at www.firstclinical.com

© 2007 Norman M. Goldfarb

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