Patient on ACEI (Analapril) suffering from dry cough. What is alternative Losartan.

patient on Digoxin from last 2 yr. suddenly loose compliance. Because Hypokalemia

A woman suddenly stops smoking. What symptom should NOT occur Headache

Patient with chronic renal failure. Which diuretic you will give Furosemide

(Side effects of Thiazide diuretics are)

Hyperurecemia, Hypokalemia,
Hyperglycemia, Hypochloremia,
Hypercalcaemia, Hypocreatinism)
Selegiline is a MAOI – B inhibitor
Bromocriptin is a Dopamine agonist.
Herpes zoster Acyclovir is used
THERAPEUTIC CHOICES IN SPECIAL CONDITIONS
Hypertension +IHD (Angina, recent MI) first line, Beta-blockers, alternatively CCB (Diltiazem, Verapamil)
Hypertension+CHF first line Diuretic, ACEI, alternative hydralazine, isosorbide dinitrate, or angiotensin II
receptor blocker.
Hypertension+ Peripheral vascular disease (raynaulds disease) first line vasodilator, CCB alternative, beta-
blockers with
ISA
Hypertension+ Dyslipedemia first line alpha-blocker, ACEI, beta-blocker with ISA, CCB, alternative low dose
Thiazide
Hypertension+ Asthma first line, K+ sparing diuretics, Thiazide diuretics for patients on Salbutamol.

Hypertension+ pregnancy, first line, Methyldopa, clonidine, hydralazine, beta-blockers, alternatively CCB or
Angiotensin II
receptor blockers.

Folic acid deficiency will affect the antiepileptic Phenytoin

Lithium has the following adverse drug reactions
a. Fine hand tremor
b. Hypothyroidism
d. Diarrhea
e. Weight gain
Flumazenil is used to treat Benzodiazepines overdose
Anemia is caused by all of these agents , ASA, Ethanol, Methyldopa

the following are used in treatment of hypothermia, Exercise & Warm I.V solution

Hydrochlorothiazide& Furosemide are used for ankle edema & Nifidipine cause ankle edema)
What is the advantage and disadvantage of estrogen and progesterone in OCP
study
a. Advantages
i. PID with the use of COCs the chances of pelvic inflammatory disease is less prevalent.
ii. The risk of developing ovarian cysts is decreased; preexisting cysts are more rapidly resolved.
The risk of ovarian cancer is reduced 33 to 66% by COCs.
iii. The cyclic COCs contain enough progesterone to prevent endometrial cancer by 50-66%.
iv. There appears to be a 50-75% reduction in the risk of fibroadenomas, chronic cystic breast
disease, and
unbiopsed breast lumps in COC users.
v. The endometrium of a COC user becomes progressively thinner; therefor prostaglandin
production (which causes dysmenorrhea) may be lower during menses.40-67% decrease in
complaints of menstrual pain. vi. Premenstrual tension has been reported to be reduced 29% in
COC users
vii. As the total amount of menstrual blood flow in COC users might be decreased by 50% this
may have a
positive effect on iron deficiency anemia.
viii. COCs can be used as postcoital morning after pill as a source of emergency contraception or
abortion. Especially ECPs (Estrogen alone)
b. Disadvantages
i. Cervical dysplasia & cervical cancer
ii. Breast cancer, some study have suggested an increase of breast cancer in young woman using
COCs withhigh progestin activity
iii. Cardiovascular disease the increase in mortality is concentrated in smoker women older then
35 year of age iv. Thromboembolic events long term COCs use is associated with an increase in
platelet count and increased platelet aggregation similar to that seen late in pregnancy and is
thought to be caused by the estrogen component. Progestin caused vasodilatation and have been
linked to sub clinical thrombosis thus, both the estrogenic and Progestational components COCs
contribute the formation of deep vein Thrombosis v. Hypertension is another side effect of COCs;
this can be due to the retention of sodium and water. vi. Diabetes, progestin decrease & estrogen
increase the number of insulin receptors on the cell membrane progestin may also alter the
insulin receptor affinity. Leading to glucose intolerance
vii. Gallbladder disease, the incidence of cholelithiasis reportedly doubles in the first year of COC
use.
viii. Headache, incidence of vascular headache is increased in women using COCs.
ix. Depression is also reported with the use of COCs, excess progestin & deficiency of estrogen
attributes to this situation.

the best treatment of pneumocystic carinii (PCP) in AIDS patientCo-trimoxazole 160/800 mg/day, or
dapsone 100 mg/day with Folinic acid 25 mg/wk or atovaquone 100 mg/day for 21 days
the long-term effects of menopause?
a. Hot flashes
b. Osteoporosis
c. Lipid levels and bone density
d. Vaginal atrophy
(Sleeplessness/ hot flushes/ lethargy/ depression / Urogenital atrophy)

Drugs which may cause asthma, Aspirin, penicillin, Propranolol.

Antipsychotic which has least extra pyramidal side effect Thioridazine.
Toxicity of Isoniazid is treated by Pyridoxine.
Drug which is cardiotoxic Doxorubicine.