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Abstract
This review considers the current status of detector developments for medical imaging using ionising radiation. This
field is divided into two major areas; the use of X-rays for transmission imaging and the use of radioactive tracers in
emission imaging (nuclear medicine). Until recently, most detector developments were for applications in nuclear
medicine. However, in the past 5 years new developments in large area, X-ray-sensitive detectors have meant that both
application domains are equally served.
In X-ray imaging, work in CT and mammography are chosen as examples of sensor developments. Photodiode
arrays in multi-slice spiral CT acquisitions are described and for mammography the use of amorphous silicon flat panel
arrays is considered. The latter is an excellent example where new detector developments have required a re-think of
traditional imaging methods.
In gamma-ray imaging the recent developments in small area, task-specific cameras are described. Their limitations
and current proposals to overcome those limitations are considered. PET has also received attention but recent clinical
emphasis has been on the development of dual-headed gamma cameras which provides both SPECT and PET
capability. Finally, some future requirements are considered. r 2002 Elsevier Science B.V. All rights reserved.
0168-9002/02/$ - see front matter r 2002 Elsevier Science B.V. All rights reserved.
PII: S 0 1 6 8 - 9 0 0 2 ( 0 1 ) 0 1 8 6 7 - 8
470 R. Speller, G. Royle / Nuclear Instruments and Methods in Physics Research A 477 (2002) 469–474
Fig. 1. The two major imaging modalities. Transmission imaging is usually carried out with X-ray sources and emission imaging using
radioisotopes.
Table 1
Comparison of performance requirements of detectors for X- and gamma-ray imaging
Table 2
Summary of digital detectors used in diagnostic X-ray imaging
Image intensifier with digitised output Currently the most common form of ‘digital imaging’ system in use
Photostimuable plates (Fuji plates) Usually called computed radiography and comparable to film in its applications and
use
CCDs Currently the most frequently used direct digital sensor. Finding many applications
in dental radiology and some in small area mammography
Photodiode arrays Used in CT systems
Amorphous Si-flat panel arrays The only large area option available in direct digital sensors. Finding uses in both
kV and MV imaging
MWPCs Some promising applications in low-dose radiology. Limited areas of application
due to spatial resolution
Microstrip sensors Both gaseous and silicon sensors are under investigation. No commercial
exploitation yet
provide up to 4 slices of data per rotation of the Screening Programme in the UK. To overcome
scanning gantry. When used in a ‘spiral’ mode this problem, magnification of the image is
where the patient is moved through the system as required that in turn requires a small focal spot
the source and detectors rotate around the patient, to avoid image unsharpness. The requirements for
large volumes of tissue can be imaged quickly the focal spot and optimisation of the scintillator
thereby eliminating patient motion. Fig. 4 is a used has been evaluated by Speller et al. [4] and
clear demonstration of the system capabilities. when used in this mode provides high-quality
Here, a three-dimensional representation of renal digital mammograms.
blood flow has been imaged in a fast spiral scan Fig. 5 is an image of the TORMAM test object
mode. [5] displayed with optimised windows for the
Mammography: Mammography is one of the different image details. When this and other
most challenging of diagnostic imaging techniques. similar test objects are ‘scored’ according to the
The normal and abnormal tissues differ in such visibility of the different features this system
subtle ways that demonstration of pathology is performs better than the most frequently used
very difficult and requires the most careful film/screen combination [4].
optimisation of all elements in the imaging system.
High spatial resolution, low dose and low contrast
detectablity are all required and digital techniques
3. Gamma-ray imaging
are just entering the market. CCDs have been used
in a variety of ways [1] but the most frequently
Three areas of activity can be identified in the
used method is ‘tiling’ a large (6 6 cm2) area
development of detector systems for imaging
using tapered light guides between a scintillator
gamma-emitting radioisotopes. They are conven-
screen and the CCD to avoid dead areas. Such
tional, large area gamma cameras, task-specific,
detectors are now used in clinical mammography
small area cameras, and cameras for positron
for symptomatic cases when re-called for biopsies
imaging. All areas are attracting significant inter-
[2]. The only large area direct digital sensor is the
est. Five years ago the major interest was in
am-Si flat panel array. These have been considered
positron imagers but the most recent interest has
for conventional radiography [3] and have recently
been in the small area, generally high-resolution
been evaluated for mammography [4]. The smal-
gamma cameras.
lest pixel size available is 127 mm which gives rise
Conventional cameras: Recent years have seen
to a maximum theoretical spatial resolution o4 lp/
the use of multi-headed cameras. Firstly, these
mm. This is well below the clinical requirement as
were developed to increase the statistical quality of
laid down by the National Health Service Breast
data by surrounding the patient with more active
detector. A typical example has three rectangular
cameras forming an equilateral triangle of active
Fig. 4. A rapid volume scan taken in 4-slice spiral mode. Fig. 5. An image of the TORMAM test object.
R. Speller, G. Royle / Nuclear Instruments and Methods in Physics Research A 477 (2002) 469–474 473
prohibitive. Current research in CdZnTe gam- areas required but other techniques and materi-
ma cameras looks promising [11]. als are being investigated.
* Better collimation: For planar and SPECT
imaging developments in collimators are The future medical applications for new sensors
needed. The work on Compton cameras [12] are endlessFalmost any new developments could
aims to provide the solution. Such devices have potentially have medical uses.
only recently had any realistic hope of achieving
clinical performance due to the advances of
microstrip detector technology. References
* Portability: Taking gamma-ray imaging devices
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