G.YUVARAJ M.Pharma.,Ph.

D
32/43 sundarm pillai street,Purasawalkam
Chennai PIN 600007 Tamil Nadu State, INDIA
Cell Phone: +91 9952968059
Email: yuvas2010@gmail.com

Career Objectives
To grow in Leadership and Knowledge – Infectious Disease, Cancer
Innovate, Develop and Apply world class solutions to real world challenges
in the above three domains of Biology

Technical Skills and Experience

• Highly qualified Research Professional with 4 years of Scientific and

Administrative experience.
• Result oriented with the ability to proactively identify and provide solutions to
research problems
areas of interest

• Pharmacokinetics and Medicinal chemistry.

• Clinical research –Bioanalytical department.
• Pharmaceutical chemistry and drug development.

 To train CRA’s about the study protocols. To develop support clinical

research Team. To formulate and review the SOP’s . To support the
protocol writing.

 To participate the technical discussion pertaining to clinical observation

and signs. Updating the knowledge on clinical trials and sharing the
information to the CR team. Delegation of duties to clinical research
assistants.

 To Lead in clinical trial management and implementation of study protocol

with special emphasis on compliance with ICH/CGP guidelines and on-site
management and collection.

 Responsibilities included clinical trial co-ordination to oversee the conduct

of the Study to ensure the quality and integrity of the data produced at
the investigator sites.
  Domain knowledge contribution in interfacing LIMS and Analytical
equipments

Educational credentials

Ph.D –Thesis work Drug Discovery&Medicinal chemistry

CPGA-9.7 in Out of ten –Sanjivani Pharmacetical sciences(Chromosoft-Sponsor)

• JSS University, Ooty.India

M. Pharm- Gold medal student-medicinal chemistry
• Dr.MGR medical University, Chennai, India
B. Pharm (2 subject Gold medal)

• Small Industries Service Institute, Chennai, India

TRAINING ATTENED ON
GLP: “Basics of Good Laboratory Practice” held on 23rd January 2006. at
Chennai

GCP: “Good Clinical Practice” held on 5th February 2006. at

Bangalore

Quality Control Chemist, AST India Ltd,Jaipur.

Analysis of Active Pharmaceutical Ingredient (API) as per IP and
USP.
 Anaysis the Pharmaceutical dosage form such as Tablet,
Capsulses, Liquid orals and Injections as per IP and
USP.
 Followed Good Laboratory Practise (GLP) analysis.

Professional Experience

Senior Scientist -Clinical Research, Chromosoft labs Clinical trials research

-1.5 yr
Current:2.5 yrs –Molecule division-Medicinal chemistry –Europe Market-
PMP(Tox,ADEMT,Bio analytical,TRIPOS(sibyl 6.7 ver)PROJECT Manager

Technical skills and abilities

 Molecular Modeling Using SYBYL 6.7 (Tripos,USA)

 Comparative molecular field analysis (3-D QSAR) using
SYBYL 6.7 version
 Organic and semi Syntheses.
 Invivo and invitro antioxidant, Heptaoprotective, Antifertility anticancer
 Knowledge in Method development and Method validation of bio analytical methods
using HPLC, UPLC and LCMSMS as per GLP and ICH guidelines.
 Knowledge in Chromatographic principles with special emphasis on HPLC, UPLC
and LC-MS/MS.
 Capability of investigating and applying new and existing techniques for the efficient
Bio analysis of drugs and drug metabolites.
 Well versed in sample preparation techniques (Protein Precipitaion, Solid Phase
extraction and Liquid-Liquid extraction) and Sample analysis.
 Well versed with the design and usage of SOPs (Standard Operating Procedures) in
my present job.
 Calibration and Maintenance of various analytical instruments like HPLC, UPLC, pH
meter, analytical balances, micropipettes, etc. as per GLP.
 Proficient in literature survey and interpretation of data.
 Excellent communication and organizational skills and ability to work to deadlines.
 Ability to work independently and as part of a team.
 Flexible approach within the working environment.
 Ability to collaborate actively with many research groups in different fields and to
initiate new contacts.
computer skills

 All Microsoft office programs, including excel, PowerPoint and word.

 Chemistry software packages including the ISIS Draw, Chem Draw.
 Familiar in LIMS(laboratory information management systems).
 E-LITERACY
 Has Good Knowledge In Ms Word, Ms Excel, Ms Powerpoint,
System Booting Etc.
 Sybyl 6.7 Version (Tripos- Usa)J.S.S Pharma

COMPUTER AIED MOLECULAR DESIGN(CAMD)

Conduct of Prestudy and Poststudy meeting

Responsibilities
• Leading the six member team in vitro anticancer department
• Cell bank Maintenance of 54 Human and Murine cancer cell lines
• Evaluation of New Molecular Entities for potential anti cancer activity by
means of

 MTT assay for antiproliferative activity.

 Assays for Apoptosis
 Assays for Signal Transduction Pathways TNFά, IFNγ,
IL6,pstat3NFKB,Bcl2 caspases.
Assay for the inhibition of Histone Deacetylase (HDAC) in both cell free
and cell based systems
 Syngenic and graft models for efficacy.
 Pre clinical data management for profiling the drug
 Participating member of phase forward of drug discovery and
development

 Dr. Siddique Gold Medal for the best article on Public Health entitled,
“Preliminary Report on the Seroprevalence of Japanese Encephalitis
among animals in Tamil Nadu” published in the Indian Veterinary Journal
for the year 1999.

 Dr. Krishnamoorthy Memorial Gold medal for the best Short

communication entitled “Enzyme linked Immunosorbent Assay for the
detection of antibodies to Canine Adenovirus Type-1” published in the
Indian Veterinary journal for the year 1997.

Professional Membership

PROFESSIONAL MEMBERSHIP:

 .Registered Pharmacist in The Tamilnadu Pharmacy Council,

Chennai.(UG&PG)
 Qualified in GATE examination.(M.Pharma-Merit student)

Instruments Known to handle

 LCMS-API-2000, 3200, 4000, Sciex Applied Bio-Systems, Canada.

 UPLC Waters Acquity, USA.
 HPLC Waters Alliance-2695, USA.
 HPLC, Shimadzu Prominence, Japan.
 HPLC, Agilent 1100 and1200 series, USA.
 FT-IR spectrometer, Perkin Elmer, USA.
 UV-Vis Spectrophotometer, Jasco, India,
  Probe Sonicator Vibra Cell, Sonics, USA.
 Automatic nitrogen evaporator, Turbo Vap LV, Zymax corp. USA.

PROJECTS HANDLED
Title: Synthesis Of pyrazoline derivative(Anti tumour/Antiangiogesis) And QSAR
Studies Including CoMFA (3-D QSAR) Of Some Possessing New Chemical Entities

Medicinal Plants in Kollimalais-A Survey.

Comparative studies on Hydroxy propyl methyl cellulose, guar gum and gum
karaya matrix tablets formulated with diclo fenac sodium

STRENGTHS

 Capable of working in a fully computerized environment

 Dynamic Personality, dedicated amicable relationship and strong desire
towards learning with management.
 Hard working and good team player.
o Self Organized, good interpersonal and communication skills.

Personal Information

Name in full (as per Passport): G.Yuvaraj

Passport Details: B3670318
Pharmacy Council Registration Number: 4834 A1
Father’s Name: P.Govindarajan
Mother’s Name: G.Kalavathy
Date of Birth: 23-04-1980
Place of Birth: Chennai, Tamil Nadu, India.
Sex: Male
Marital Status: Married
Nationality: Indian
 PUBLICATIONS

Puplication
National – 17 / International - 38

Presentation-Seminar

USA, Canada, Singapore, South Africa

Vision:

In the phase of advancing technology in combinatorial synthesis and

HTS,the drug discovery process continues to evolve. Preclinical drug
metabolism & PK studies play a key role in lead identification