NATIONAL AERONAUTICS AND SPACE ADMINISTRATION

SPACE SHUTTLE
MISSION
STS-40
PRESS KIT
MAY 1991

SPACELAB LIFE SCIENCES-1 (SLS-1)

 STS-40 CREW INSIGNIA
STS040-S-001 -- The STS-40 insignia makes a contemporary statement focusing on human beings living and
working in space. Against a background of the universe, each of the seven Shuttle crew members is represented by
one of seven silver starts interspersed about the orbital path of the Space Shuttle Columbia. The orbiter's flight path
forms a double-helix designed to represent the DNA molecule common to all living creatures. It affirms the
ceaseless expansion of human life and American involvement in space while simultaneously emphasizing the
medical and biological studies to which this flight is dedicated. Above Columbia, the phrase "Spacelab Life Sciences
1" defines both the shuttle mission and its payload. In the upper center portion of the patch, silhouetted against the
blue darkness of the heavens, stands Leonardo da Vinci's Vitruvian man. With one foot on Earth and arms extended
to touch the shuttle's orbit, he serves as a powerful embodiment of the extension of human inquiry from the
boundaries of Earth to the limitless laboratory of space. Studily poised amid the stars, he serves to link scientists on
Earth to the scientists in space asserting the harmony of efforts which produce meaningful scientific space flight
missions. At the center of the patch is a brilliant red and yellow Earth-limb linking Earth to space and radiating
from a native American symbol for the sun. At the frontier of space, this traditional symbol for the sun vividly links
America's past to America's future. Beneath the orbiting shuttle, darkness of night rests peacefully over the United
States. Drawn by artist Sean Collins, the STS-40 space shuttle insignia was designed by the crew members for the
flight.

The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as
the NASA Administrator may authorize. Public availability has been approved only in the form of illustrations by the
various news media. When and if there is any change in this policy, which we do not anticipate, it will be publicly
announced.

PHOTO CREDIT: NASA or National Aeronautics and Space Administration.

 SPACELAB LIFE SCIENCES 1 INSIGNIA

S86-27614 -- The Space Shuttle Columbia is at the center of the Spacelab Life Sciences 1 insignia. The various
elements serve to deliver the message of the dedication of this mission to medical and biological studies, a first for
manned spaceflight. A crew of five NASA astronauts and the payload specialists will be split into shifts to maximize
the exposure to space environment for variegated and thorough biological and medical experiments during the
scheduled ten-day mission. The crew will maintain a constant communications link with scientists on Earth,
considered by the flight crew to be an integral part of the overall mission, as well. NOTE: After this patch was
designed, the SLS-1 mission was assigned to fly as NASA's STS-40 flight, scheduled for May 1991.

The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as
the NASA Administrator may authorize. Public availability has been approved only in the form of illustrations by the
various news media. When and if there is any change in this policy, which we do not anticipate, it will be publicly
announced.

PHOTO CREDIT: NASA or National Aeronautics and Space Administration.

NASA PUBLIC AFFAIRS CONTACTS
Mark Hess/Jim Cast/Ed Campion
Office of Space Flight
NASA Headquarters, Washington, DC
(Phone: 202/453-1134 or 202/453-8536)

Paula Cleggett-Haleim
Office of Space Science and Applications
NASA Headquarters, Washington, DC
(Phone: 202/453-1547)

Lisa Malone
Kennedy Space Center, FL
(Phone: 407/867-2468)

Mike Simmons
Marshall Space Flight Center, Huntsville, AL
(Phone: 205/544-6537)

James Hartsfield
Johnson Space Center, Houston, TX
(Phone: 713/483-5111)

Jean Drummond Clough

Langley Research Center, Hampton, VA
(Phone: 804/864-6122)

Dolores Beasley
Goddard Space Flight Center, Greenbelt, MD
(Phone: 301/286-2806)

Myron Webb
Stennis Space Center, Bay St. Louis, MS
(Phone: 601/688-3341)

Nancy Lovato
Ames-Dryden Flight Research Facility, Edwards, CA
(Phone: 805/258-3448)
 CONTENTS
GENERAL RELEASE 6

MEDIA SERVICES 7

STS-40 QUICK LOOK 8

SUMMARY OF MAJOR ACTIVITIES 9

SPACE SHUTTLE ABORT MODES 10

VEHICLE AND PAYLOAD WEIGHTS 11

FLIGHT SEQUENCE OF EVENTS 12

STS-40 PRELAUNCH PROCESSING 13

SPACELAB LIFE SCIENCES (SLS-1) 14

VESTIBULAR EXPERIMENTS IN SPACELAB 17

AMES RESEARCH CENTER EXPERIMENTS 25

GET AWAY SPECIAL EXPERIMENTS 29

ORBITER EXPERIMENTS PROGRAM 33

STS-40 CREW BIOGRAPHIES 35

STS-40 MISSION MANAGEMENT 38

 RELEASE: 91-69 May 1991

FIRST SPACELAB DEDICATED TO LIFE SCIENCES HIGHLIGHTS STS-40

Shuttle mission STS-40, the 41st flight of the Space Shuttle and the 11th flight of Columbia, will conduct the
Spacelab Life Sciences (SLS-1) mission, the first Spacelab dedicated to life sciences research.

The launch of the SLS-1 mission is currently scheduled for no earlier than 9:20 a.m. EDT on May 24. The mission
will be flown at an altitude of 160 by 150 nautical miles and at an inclination of 39 degrees to the Equator.

During the SLS-1 mission, the STS-40 crew will perform experiments which will explore how the heart, blood
vessels, lungs, kidneys and hormone-secreting glands respond to microgravity, the causes of space sickness and
changes in muscles, bones and cells during the microgravity environment of space flight and in the readjustment to
gravity upon returning to Earth. The experiments performed on Columbia's crew and on laboratory animals will
provide the most detailed and interrelated physiological measurements acquired in the space flight environment
since the Skylab program flights in 1973 and 1974.

Other payloads on the SLS-1 mission include 12 experiments being flown under NASA's Get Away Special
program. The experiments, enclosed in canisters on a bridge in the Shuttle's cargo bay, will investigate such topics
as materials science, plant biology and cosmic radiation.

The NASA Orbiter Experiments Program will fly 7 experiments on the STS-40 orbiter that will provide an
opportunity for researchers to gather data on a full-scale lifting vehicle, the STS-40 orbiter, during atmospheric
entry.

The mission is planned to last 9 days, 3 hours and 30 minutes, concluding with a landing at Edwards Air Force
Base, Calif., at 12:50 p.m. EDT, June 2. The Commander for this flight of Columbia will be Marine Corps Col.
Bryan D. O'Connor. Air Force Lt. Col. Sidney M. Gutierrez will serve as Pilot. Mission specialists for STS-40 are
James P. Bagian, MD; Tamara E. Jernigan, Ph.D.; and Margaret Rhea Seddon, MD. The payload specialists are
Francis Andrew Gaffney, MD, and Millie Hughes-Fulford, Ph.D..

Following the STS-40 mission, Columbia will return to Kennedy Space Center, Fla., where the Spacelab will be
removed. The orbiter will then go to Palmdale, Calif., for nearly 6 months to undergo major modifications and
inspections at Rockwell International Corp. Columbia is next scheduled to fly on STS- 50, the U. S. Microgravity
Laboratory mission, in June 1992.

(END OF GENERAL RELEASE; BACKGROUND INFORMATION FOLLOWS.)

 MEDIA SERVICES
NASA Select Television Transmissions

NASA Select television is available on Satcom F-2R, Transponder 13, located at 72 degrees west
longitude; frequency 3960.0 MHz, audio 6.8 MHz.

The schedule for television transmissions from the orbiter and for the change-of-shift briefings from
Johnson Space Center, Houston, will be available during the mission at Kennedy Space Center, Fla.;
Marshall Space Flight Center, Huntsville, Ala.; Johnson Space Center; and NASA Headquarters,
Washington, DC. The television schedule will be updated to reflect changes dictated by mission
operations.

Television schedules also may be obtained by calling COMSTOR, 713/483-5817. COMSTOR is a

computer data base service requiring the use of a telephone modem. A voice update of the television
schedule may be obtained by dialing 202/755-1788. This service is updated daily at noon EST.

Status Reports

Status reports on countdown and mission progress, on-orbit activities and landing operations will be
produced by the appropriate NASA news center.

Briefings

A mission press briefing schedule will be issued prior to launch. During the mission, change-of-shift
briefings by the off-going flight director will occur at approximately 8-hour intervals.
 STS-40 QUICK LOOK
Launch Date: May 24, 1991

Launch Site: Kennedy Space Center, Fla., Pad 39B

Launch Window: 8:00 a.m. - 10:00 a.m. EDT

Orbiter: Columbia (OV-102)

Orbit: 160 by 150 nautical miles

Inclination: 39 degrees

Landing Date/Time: 11:00 a.m. - 1:00 p.m. PDT, June 2, 1991

Primary Landing Site: Edwards Air Force Base, CA

Abort Landing Sites: Return to Launch Site: Kennedy Space Center, FL

Transoceanic Abort Landing - Ben Guerir, Morocco
Abort Once Around - White Sands Space Harbor, NM

Crew: Bryan D. O'Connor, Commander

Sidney M. Gutierrez, Pilot
James P. Bagian, Mission Specialist 1
Tamara E. Jernigan, Mission Specialist 2
M. Rhea Seddon, Mission Specialist 3
Francis A. (Drew) Gaffney, Payload Specialist 1
Millie Hughes-Fulford, Payload Specialist 2

Cargo Bay Payloads: Spacelab Life Sciences-1 (SLS-1)

Get Away Special (GAS) Bridge experiments

Middeck Payloads: Physiological Monitoring System (PMS)

Urine Monitoring System (UMS)
Animal Enclosure Modules (AEM)
 SUMMARY OF MAJOR ACTIVITIES
Flight Day 1
Ascent
OMS 2 engine firing
Spacelab activation
Metabolic experiment operations
Echocardiograph operations

Flight Day 2
Baroreflex tests
Pulmonary function tests
Echocardiograph activities
Cardiovascular operations
Ames Research Center operations

Flight Day 3
Ames Research Center operations
Rotating dome operations
Echocardiograph activities
DTOs

Flight Day 4
Baroreflex/Pulmonary function tests
Ames Research Center operations

Flight Day 5
Pulmonary function tests
Cardiovascular operations
Echocardiograph activities

Flight Day 6
Rotating dome operations
Echocardiograph activities
Cardiovascular operations
Ames Research Center operations

Flight Day 7
DTOs
Ames Research Center operations

Flight Day 8
Baroreflex tests
Echocardiograph
Cardiovascular operations

Flight Day 9
Pulmonary function tests
Flight control systems checkout
Echocardiograph tests
Cardiovascular operations
Cabin stow
Partial Spacelab deactivation

Flight Day Ten

Spacelab deactivation
Deorbit preparation
Deorbit burn
Landing
 SPACE SHUTTLE ABORT MODES
Space Shuttle launch abort philosophy aims toward safe and intact recovery of the flight crew, orbiter and
its payload. Abort modes include:

• Abort-To-Orbit (ATO) -- Partial loss of main engine thrust late enough to permit reaching a minimal 105-
nautical mile orbit with orbital maneuvering system engines.

• Abort-Once-Around (AOA) -- Earlier main engine shutdown with the capability to allow one orbit around
before landing at either Edwards Air Force Base, Calif.; the Shuttle Landing Facility (SLF) at Kennedy Space
Center, Fla.; or White Sands Space Harbor (Northrup Strip), NM.

• Transatlantic Abort Landing (TAL) -- Loss of one or more main engines midway through powered flight would
force a landing at either Ben Guerir, Morocco; Moron or Zaragoza, Spain.

• Return-To-Launch-Site (RTLS) -- Early shutdown of one or more engines, and without enough energy to reach
Ben Guerir would result in a pitch around and thrust back toward Kennedy Space Center, Fla., until within
gliding distance of the SLF.

STS-40 contingency landing sites are Edwards AFB, Kennedy Space Center, White Sands, Ben Guerir, Moron and
Zaragoza.
 VEHICLE AND PAYLOAD WEIGHTS
Pounds

Orbiter (Columbia), empty and 3 SSMEs 172,482

Spacelab Life Sciences-1 Module 21,271

GAS Bridge Assembly 4,885

Spacelab Support Equipment 750

Space Acceleration Measurement System 250

Detailed Test Objectives 88

Detailed Supplementary Objectives 35

Total Vehicle at SRB Ignition 4,519,081

Orbiter Landing Weight 225,492

 FLIGHT SEQUENCE OF EVENTS

MET Relative Altitude

Event (d/h:m:s) Velocity (fps) Mach (ft)

Launch 00/00:00.00

Begin Roll Maneuver 00/00:00:10 189 0.17 799

End Roll Maneuver 00/00:00:18 403 0.36 3,286

SSME Throttle Down to 67% 00/00:00:33 784 0.71 11,283

Max. Dyn. Pressure (Max Q) 00/00:00:52 1,183 1.14 27,829

SSME Throttle Up to 104% 00/00:01:04 1,504 1.54 41,579

SRB Staging 00/00:02:05 4,136 3.85 155,954

Main Engine Cutoff (MECO) 00/00:08:33 24,644 22.27 367,999

Zero Thrust 00/00:08:40 24,673 22.3 370,235

ET Separation 00/00:08:50

OMS 2 Burn 00/00:42:20

Deorbit Burn (orbit 146) 09/02:31:00

Landing (orbit 147) 09/03:30:00

Apogee, Perigee at MECO: 155 x 40 nautical miles

Apogee, Perigee post-OMS 2: 160 x 150 nautical miles
 STS-40 PRELAUNCH PROCESSING
Processing the orbiter Columbia for the STS-40 mission at Kennedy Space Center began Feb. 9, following its last
mission - STS-35/Astro I.

About 40 modifications were made to Columbia during its 10 and a half-week stay in the OPF. These modifications
enhance the performance and efficiency of the orbiter's complex systems. While in the OPF, four modified external
tank door bellcrank housings were installed. Small cracks previously were found in three of the housings.

Space Shuttle main engine locations for this flight are as follows: engine 2015 in the No. 1 position, engine 2022 in
the No. 2 position and engine 2027 in the No. 3 position. These engines were installed in March.

The Crew Equipment Interface Test with the STS-40 flight crew was conducted on April 7 in the OPF. This test
provided an opportunity for the crew to become familiar with the configuration of the orbiter and anything that is
unique to the STS-40 mission.

Technicians installed the Spacelab module on March 24 and successfully conducted the required tests. The Spacelab
tunnel, leading from the orbiter's airlock to the module, was installed April 3.

Booster stacking operations on mobile launcher platform 3 began March 16 with the left and right aft boosters.
These segments later were destacked to allow a realignment of the launch platform holddown posts. Restacking
began on March 23 with the left aft booster. Stacking of all booster segments was completed by April 11. The
external tank was mated to the boosters on April 17 and Columbia was transferred to the Vehicle Assembly Building
on April 26 where it was mated to the external tank and solid rocket boosters.

The STS-40 vehicle was rolled out to Launch Pad 39-B on May 2. A launch countdown dress rehearsal was
scheduled for May 6-7 at Kennedy Space Center.

A standard 43-hour launch countdown is scheduled to begin three days prior to launch. During the countdown, the
orbiter's onboard fuel and oxidizer storage tanks will be loaded and all orbiter systems will be prepared for flight.

About 9 hours before launch, the external tank will be filled with its flight load of a half a million gallons of liquid
oxygen and liquid hydrogen propellants. About two and one-half hours before liftoff, the flight crew will begin
taking their assigned seats in the crew cabin.

KSC's recovery teams will prepare the orbiter Columbia for the return trip to Florida following the end-of- mission
landing at Edwards AFB, Calif. Orbiter turnaround operations at Dryden Flight Research Facility typically take
about five days. A 2-day ferry flight is planned because of the additional weight of the orbiter returning with the
Spacelab. The extra weight will require several refueling stops during the ferry flight.

Following post-flight deservicing and removal of the Spacelab payload and major orbiter components at Kennedy
Space Center, Columbia will be readied for ferry flight to Palmdale, Calif. The orbiter is scheduled to undergo
extensive modifications, including changes to accommodate an extended duration mission, at the Rockwell
manufacturing plant during a 6-month period from August 1991 to January 1992. Columbia's next scheduled flight
is STS-50, a planned extended duration mission with the U.S. Microgravity Laboratory payload targeted for launch
in June 1992.
 SPACELAB LIFE SCIENCES (SLS-1
Many volumes of research remain to be recorded and studied regarding adaptation of humans to the weightless
environment of space flight. The blanks, however, will begin to be filled following the broad range of experiments
to be conducted on the Spacelab Life Sciences-1 (SLS-1).
With the help of the STS-40 crew, investigators from across the nation will conduct tests on the cardiovascular,
cardiopulmonary, metabolic, musculoskeletal and neurovestibular systems.

There are 18 primary experiments chosen for SLS-1. Those using human subjects are managed by the Lyndon B.
Johnson Space Center, Houston, Texas, and those using animals are managed by the Ames Research Center, Moffett
Field, Calif. Organized by the managing NASA center, this section of the press kit will summarize the 18
experiments, identify the principal investigators and list flight hardware used to support the experiments.

Johnson Space Center

Spacelab Life Sciences-1 Experiments

Activities involved with the human experiments on-board Columbia are managed by the Lyndon B. Johnson Space
Center, Houston, Texas. Preflight baseline data collection will be performed primarily at Johnson Space Center with
several tests scheduled at the Kennedy Space Center just prior to launch. Investigators will perform post-flight tests
at the Ames-Dryden Flight Research Facility, Edwards, Calif.

A broad range of instruments -- some, unique hardware and others, standard equipment -- will be used by the human
subjects throughout the mission. Equipment will include a neck chamber, cardiopulmonary rebreathing unit, gas
analyzer mass spectrometer, rotating dome, inflight blood collection system, urine monitoring system, bag-in-box
assembly, strip chart recorders, physiological monitoring system, incubators, low-gravity centrifuge,
echocardiograph and venous occlusion cuff controller.

In total, the 10 experiments will explore the capabilities of the human body in space. A brief description of these
experiments follows:

Influence Of Weightlessness Upon Human Autonomic Cardiovascular Controls

Principal investigator:
Dwain L. Eckberg, MD
Medical College of Virginia Richmond, VA

This experiment will investigate the theory that lightheadedness and a reduction in blood pressures in astronauts
upon standing after landing may arise because the normal reflex system regulating blood pressure behaves
differently after having adapted to a microgravity environment.

For this experiment, some SLS-1 crewmembers will wear neck chambers that resemble whip-lash collars to detect
blood pressure in the neck. Investigators will take blood pressure measurements both before and after the flight for
comparison. Astronauts will take the same measurements themselves on orbit to map changes that occur during
spaceflight.
Inflight Study Of Cardiovascular Deconditioning

Principal investigator:

Leon E. Farhi, MD
State University of New York at Buffalo
Buffalo, NY

Just how rapidly astronauts become accustomed to microgravity and then readjust to the normal gravitational forces
on Earth is the focus of this study. By analyzing the gas composition of a mixture which the STS-40 astronauts
"rebreathe," investigators will calculate how much blood is being delivered by the heart to the body during space
flight.

This experiment uses a non-invasive technique of prolonged expiration and rebreathing -- inhaling in previously
exhaled gases -- to measure the cardiovascular and respiratory changes. The technique furnishes information on
functions including the amount of blood pumped out of the heart, oxygen usage and carbon dioxide released by the
body, heart contractions, blood pressure and lung functioning.

Astronauts will perform the rebreathing technique while resting and while pedaling on an exercise bike to provide a
look at the heart's ability to cope with added physical stress. On the first and last days of the STS-40 mission, only
resting measurements will be taken. Rest and graded exercise measurements are made on most other days.
 VESTIBULAR EXPERIMENTS IN SPACELAB
Principal investigator:

Laurence R. Young, Sc. D. Massachusetts Institute of Technology

Cambridge, MA

A joint U.S./Canadian research program has been developed to perform a set of closely related experiments to
investigate space motion sickness, any associated changes in inner ear vestibular function during weightlessness and
the impact of those changes postflight. Parts of this experiment will be carried out inflight, other parts on the ground
both pre- and post-flight.
As part of the inflight activities, the team will study the interaction between conflicting visual, vestibular and tactile
information. Investigators expect crew members to become increasingly dependent on visual and tactile cues for
spatial orientation. The test calls for a crew member to place his/her head in a rotating dome hemispherical display
to induce a sensation of self-rotation in the direction opposite to the dome rotation. The astronaut will then move a
joy stick to indicate his/her perception of self-motion.

Awareness of position by astronauts is important for reaching tasks especially during landing operations. The
objective of several tests during the flight will document the loss of sense of orientation and limb position in the
absence of visual cues and will determine what mechanisms underlie the phenomenon.

During the presleep period, crewmembers will view several targets placed about the interior of Spacelab. They then
will be blindfolded and asked to describe the position of their limbs in reference to their torso and to point to the
targets. In post sleep, crew members upon waking and while blindfolded perceive their posture, position of their
limbs and location of familiar orbiter structures, recording the accuracy of their perceptions.

The next two parts of this experiment will be performed as time permits on the SLS-1 mission or continued on a
later Spacelab mission. Both experiments have been previously performed by crewmembers in space.

The next part looks at the causes and treatment of space motion sickness (SMS) and evaluates the success of Earth-
based tests to predict SMS susceptibility. Two crew members will wear an acceleration recording unit (ARU) to
measure all head movement and to provide detailed commentary regarding the time, course and signs of SMS.

Subjects wearing the ARU will wear the collar for several hours during the mission and if desired, when symptoms
occur. The influence of the collar on the resulting head movement pattern and SMS symptoms will be monitored.

Another battery of tests performed preflight will attempt to determine which test or combination of tests could aid in
predicting SMS.

Protein Metabolism During Space Flight

Principal investigator:

T. Peter Stein, Ph.D. University of Medicine and Dentistry of New Jersey

Camden, NJ

This study involves several tests looking at the mechanisms involved in protein metabolism including changes in
protein synthesis rates, muscle breakdown rates and use of dietary nitrogen in a weightless environment.

This experiment will examine whole body protein metabolism by measuring the concentration of 15N- glycine, an
amino acid in protein, in saliva and urine samples from crew members and ground control subjects preflight, inflight
and postflight.

Crew members will collect urine samples throughout the flight. On the second and eighth flight days, astronauts also
will take oral doses of 15N-glycine. Crew members will collect and freeze a urine sample 10 hours after the
ingestion of the glycine for postflight analyses. Urinary 3-methyl histidine, a marker for muscle protein breakdown
also will be monitored.

Fluid-Electrolyte Regulation During Spaceflight

Principal investigator:

Carolyn Leach-Huntoon, Ph.D. Lyndon B. Johnson Space Center

Houston, TX

Adaptation to the weightless environment is known to change fluid, electrolyte, renal and circulatory processes in
humans. A shift of body fluids from the lower limbs to the upper body occurs to all astronauts while in space.

This experiment makes detailed measurements before, during and after flight to determine immediate and long-term
changes in kidney function; changes in water, salt and mineral balance; shifts in body fluids from cells and tissues;
and immediate and long-term changes in levels of hormones which affect kidney function and circulation.

Test protocol requires that crew members collect urine samples throughout the flight. Body mass is measured daily
and a log is kept of all food, fluids and medication taken in flight. Fasting blood samples are collected from the crew
members as soon as possible inflight and at specified intervals on selected flight days thereafter.
Tests will determine the amount of certain tracers that can be released from a given volume of blood or plasma into
urine in a specified amount of time, measuring the rate and loss of body water and determining changes in blood
plasma volume and extracellular fluid. Measurements will be made two times inflight by collecting blood samples at
timed intervals after each subject has received a precalculated dose of a tracer, a chemical which allows the
compound to be tracked as it moves through the body. Total body water is measured during flight using water
labeled with a heavy isotope of oxygen.

Each subject drinks a premeasured dose of the tracer and subsequently collects urine samples at timed intervals.
Plasma volume and extracellular fluid volume are measured by collecting blood samples at timed intervals after
tracer injections. Hormonal changes are investigated by sensitive assays of both plasma and urine.

Pulmonary Function During Weightlessness

Principal investigator:

John B. West, MD/Ph.D. University of California

San Diego, CA

This experiment provides an opportunity for study of the properties of the human lung without the influence of
gravity. In the microgravity Spacelab, a model of lung function will be developed to serve as a basis for comparison
for the normal and diseased lung. Also, investigators will glean information about the lung for planning longer space
missions.

There will be a series of eight breath tests conducted with measurements taken at rest and after breathing various test
bag mixtures. The test assembly allows the subject to switch from breathing cabin air to inhaling premixed gases in
separate breathing bags. Breathing exercises involve the inhalation of specially prepared gas mixtures.

The tests are designed to examine the distribution and movement of blood and gas within the pulmonary system and
how these measurements compare to normal respiration. By measuring gas concentrations, the flow of gas through
the lungs into the blood stream and rate of blood flow into the lungs, investigators hope to better understand the
human pulmonary function here on Earth and learn how gravity plays a part in influencing lung function.
Lymphocyte Proliferation In Weightlessness

Principal investigator:

Augusto Cogoli, Ph.D. Swiss Federal Institute of Technology

Zurich, Switzerland

Following investigations carried out during Spacelab 1 and the German D-1 shuttle missions, this experiment will
investigate the effect of weightlessness on the activation of lymphocyte reproduction. The study also will test
whether there is a possible alteration of the cells responsible for part of the immune defense system during space
flight.

STS-40 will repeat the basic Spacelab-1 experiment. Lymphocytes will be purified from human blood collected 12
hours before launch. The cells will be resuspended in a culture medium, sealed in culture blocks and stowed on
Columbia's middeck. Inflight, the samples will be exposed to a mitogen (a substance that promotes cell division) and
allowed to grow in the weightless environment. Some of the samples also will be exposed to varying gravity levels
on the low-gravity centrifuge. These samples will serve as a control group as they will experience the same
environmental conditions with the exception of micro- gravity.

The stimulation of the lymphocytes to reproduce is determined by monitoring the incorporation of a chemical
isotope tracer into the cells' DNA. Investigators will gather further information on lymphocytes from blood samples
taken from the crew inflight.

Influence Of Space Flight On Erythrokinetics In Man

Principal investigator:

Clarence Alfrey, MD Baylor College of Medicine

Houston, TX

The most consistent finding from space flight is the decrease in circulating red blood cells or erythrocytes and
subsequent reduction in the oxygen carrying capacity of the blood. This experiment studies the mechanisms which
may be responsible for this decrease, including the effect of space flight on red blood cell production rate and the
role of changes in body weight and plasma volume on red blood cell production.
Blood samples taken pre-, post- and inflight will trace the life of astronauts' red blood cells. By measuring the
volume of red blood cells and plasma, researchers will check the rate of production and destruction of blood in both
normal and microgravity conditions.

On flight day two, crew members will receive an injection of a tracer that will measure the amount of new red blood
cells. Tracers (chemicals that will attach to the red blood cell to allowing them to be tracked) injected before launch
will measure the destruction rate of red blood cells. Crew members will draw blood samples on the second, third,
fourth, eighth and ninth days of flight.

Cardiovascular Adaptation To Microgravity

Principal investigator:

C. Gunnar Blomqvist, MD University of Texas Southwestern Medical Center

Dallas, TX

This experiment will focus on the acute changes in cardiovascular function, heart dimensions and function at rest,
response to maximal exercise and control mechanisms.
The experiment seeks to increase the understanding of microgravity-induced changes in the cardiovascular structure
and function responsible for a common problem during return to normal gravity of orthostatic hypotension or the
inability to maintain normal blood pressure and flow while in an upright position.

Central venous pressure -- measurements of changes in the blood pressure in the great veins near the heart -- will be
observed in one crew member. A cardiologist will insert a catheter into a vein in the arm and position it near the
heart prior to flight. Measurements then will be recorded for 24 hours beginning prior to launch and extending for at
least 4 hours into space flight, at which time the catheter is removed. The catheter data will indicate the degree of
body fluid redistribution and the speed at which the redistribution occurs.

Echocardiograph measurements, a method of sending high frequency sound into the body to provide a view of the
heart, will be performed on crew members each day.

Leg flow and compliance measurements will gather information on leg blood flow and leg vein pressure- volume
relationships. During flow measurements, blood in the veins of the leg will be stopped for a short period of time by
inflating a cuff above the knee. Compliance measurements, the amount of blood that pools for a given increased
pressure in the veins will be obtained by inflating and incrementally deflating the cuff over different pressures and
holding that pressure until the volume of the leg reaches an equilibrium.

Pathophysiology Of Mineral Loss During Space Flight

Principal investigator:

Claude D. Arnaud, MD University of California

San Francisco, CA

Changes in calcium balance during space flight is an area of concern for researchers since the changes appear to be
similar to those observed in humans with osteoporosis, a condition in which bone mass decreases and the bones
become porous and brittle and are prone to fracturing or breaking. Because of potential health problems for
astronauts returning to Earth after long space flights, the mechanisms which cause these changes are of great interest
in space medicine.

This experiment will measure the changes which occur during space flight in circulating levels of calcium
metabolizing hormones and to directly measure the uptake and release of calcium in the body. Investigators believe
there may be significant changes in the amount of these hormones produced due to an increase in the breakdown and
reassimilation of bone tissue and that these changes begin to occur within hours after entering the weightless
environment.
Each crew member will be weighed daily and will keep a log of all food, fluids and medications ingested. They also
will draw blood samples on selected days to determine the role of calcium regulating hormones on the observed
changes in calcium balance. The experiment is repeated on selected days preflight and postflight. A simultaneous
ground experiment is performed using non-crew member subjects.
 AMES RESEARCH CENTER SPACELAB LIFE SCIENCES-1 EXPERIMENTS
The Ames Research Center, Moffett Field, Calif., as the developer of nonhuman life sciences experiments, will
supply eight investigations to the SLS-1 mission. They are designed to increase our knowledge about the functioning
of basic life processes during exposure to microgravity.

These experiments will examine three systems: musculoskeletal, neurovestibular and hematopoietic. Seven of the
investigations will use laboratory rats as subjects. A gravitational biology experiment will study jellyfish
development and behavior. Ames Research Center also has developed several pieces of flight hardware to support
these experiments.

The Ames payload consists of a research animal holding facility (RAHF), two animal enclosure modules (AEMs), a
general purpose work station and associated general purpose transfer unit, a refrigerator/incubator module, a small
mass measuring instrument and eight animal experiments. A brief description of each of those experiments follows.

Regulation Of Erythropoiesis During Space Flight

Principal investigator:

Robert D. Lange, MD University of Tennessee Medical Center

Knoxville, TN

Regulation Of Blood Volume During Space Flight

Principal investigator:

Clarence Alfrey, MD Baylor College of Medicine

Houston, TX

This combined investigation will explore the mechanisms for changes seen in red blood cell mass and blood volume
in crews on previous space flights. Several factors known to affect erythropoiesis will be examined. It also will
determine whether comparable changes occur in the rat and if the rat is a satisfactory model for studying
microgravity-induced changes in human blood.
Previous space flight crews have consistently exhibited decreased red blood cell mass and plasma volume. The
mechanisms responsible for these changes are not known, although a decrease in red blood cell production may play
a role in altered red cell mass.

The SLS-1 hematology experiments will study two parts of the blood system: the liquid portion (plasma), which
contains water, proteins, nutrients, electrolytes, hormones and metabolic wastes and a cellular portion, which
contains red and white blood cells and platelets.

Bone, Calcium And Space Flight

Principal investigator:

Emily Morey-Holton, Ph.D. NASA Ames Research Center

Moffett Field, CA

Weightlessness causes a slow loss of calcium and phosphorus from the bones during and immediately following
space flight. Negative calcium balance, decreased bone density and inhibition of bone formation have been reported.
Most of the loss is thought to occur in the leg bones and the spine, which are responsible for movement and erect
posture.
Previous studies of rodents exposed to microgravity have shown decreased skeletal growth early in the mission;
reduced concentrations of a protein secreted by bone-forming cells, suggesting a reduction in the activity of these
cells; and reduced leg bone breaking strength and reduced bone mass in the spine.

Formation of bone probably does not cease abruptly, but more likely decreases gradually as the number and/or
activity of bone- forming cells decreases. This experiment will allow more precise calculation of the length of flight
time required to significantly inhibit bone formation in rats.

Dr. Morey-Holton's experiment focuses on growth that occurs in a number of specific bones such as the leg, spine
and jaw. The study also will document alterations in bone growth patterns and bone-breaking strength in rodents
exposed to weightlessness and it will determine whether bone formation returns to normal levels after space flight.
A Study Of The Effects Of Space Travel On Mammalian Gravity Receptors

Principal investigator:

Muriel Ross, Ph.D. NASA Ames Research Center

Moffett Field, CA

The neurovestibular system, which helps animals orient their bodies, is very sensitive to gravity. In space, gravity no
longer influences the tiny otolith crystals, which are small, calcified gravity receptors in the inner ear. In micro-
gravity, information sent to the brain from the inner ear and other sensory organs may conflict with cues anticipated
from past experiences in Earth's normal gravity field. This conflict results in disorientation.

Previous flight experience has shown that vestibular symptoms, including nausea, vomiting and dizziness and
instability when standing, occur in more than half of the astronauts during the first few days of flight, with some
symptoms lasting for up to 10 days post-flight.

This study investigates structural changes that may occur within the inner ear in response to the microgravity of
space. It seeks to define the effects of prolonged weightlessness on the otoliths. Scientists suspect that otolith
degeneration may occur as a result of changes in the body's calcium levels, carbohydrate and protein metabolism,
body fluid distribution and hormone secretions.

The study also will examine the degree to which any changes noted remain static, progress or recover during a 7-day
period post-flight.

Effects Of Microgravity-Induced Weightlessness On Aurelia Ephyra Differentiation And Statolith Synthesis

Principal investigator:

Dorothy B. Spangenberg, Ph.D. Eastern Virginia Medical School

Norfolk, VA

Jellyfish are among the simplest organisms possessing a nervous system. They use structures called rhophalia to
maintain their correct orientation in water. Rhophalia have statoliths that are analogous to mammalian otoliths, the
gravity-sensing organs of the inner ear that help mammals maintain balance.

The purpose of this investigation is to determine the role microgravity plays in the development and function of
gravity- receptor structures of Aurelia (a type of jellyfish). Ephyrae are a tiny form of the jellyfish. This experiment
will study the gravity receptors of ephyrae to determine how microgravity influences their development and
function, as well as the animals' swimming behavior.

Skeletal Myosin Isoenzymes In Rats Exposed To Microgravity

Principal investigator:

Joseph Foon Yoong Hoh, Ph.D. University of Sydney

Sydney, Australia

Skeletal muscle fibers exist in two forms, classified as slow- twitch or fast-twitch, depending on how fast they
contract. The two forms develop similar forces when contracting but they contract at different speeds. The speed of
contraction is directly related to the amount of the protein myosin in muscle fibers. Myosin is made up of five
isoenzymes, which differ in structure and in enzyme activity.

In Earth's gravity, a low-firing frequency stimulates the slow- twitch fibers, which support a body against gravity.
The fast- twitch fibers, which are related to body movement, contract in response to high- frequency nerve impulses.
This study will examine how microgravity affects the speed of muscle contractions. Because stimuli to the slow-
twitch anti- gravity muscles should be greatly reduced in microgravity, the concentration of myosin isoenzymes in
these fibers should be lower. This experiment should provide additional data to help explain how microgravity
affects the speed of muscle contractions and the growth and proliferation of slow-twitch and fast-twitch muscle
fibers.

Effects Of Microgravity On Biochemical And Metabolic Properties Of Skeletal Muscle In Rats

Principal investigator:

Kenneth M. Baldwin, Ph.D. University of California

Irvine, CA

It has been proposed that a loss of muscle mass in astronauts during weightlessness produces the observed loss of
strength and endurance, particularly in the anti-gravity muscles. One explanation is that exposure to microgravity
results in the removal of sufficient stress or tension on the muscles to maintain adequate levels of certain proteins
and enzymes.

These proteins and enzymes enable cells to use oxygen to convert nutrients into energy. When gravitational stress is
reduced, protein activity also decreases and muscles become more dependent on glycogen stored in the liver and
muscles for energy. As the body metabolizes glycogen, muscle endurance decreases.

Radioactive carbon compounds will be used to evaluate energy metabolism in the hind leg muscles of the rats
exposed to microgravity. The concentration of the enzymes reflects the kind of metabolic activity occurring in
muscles during periods of reduced gravitational stress. In addition, skeletal muscle cells of flight and ground-control
animals will be compared to assess any changes in the concentration of enzymes that break down glycogen.

The Effects Of Microgravity On The Electron Microscopy, Histochemistry And Protease Activities Of Rat
Hindlimb Muscles

Principal investigator:

Danny A. Riley, Ph.D. Medical College of Wisconsin

Milwaukee, WI

The anti-gravity skeletal muscles of astronauts exposed to microgravity for extended periods exhibit progressive
weakness. Studies of rodents flown in space for 7 days on a previous mission have shown a 40 percent loss of mass
in the anti-gravity leg muscles. Other studies indicate the loss of strength may result from simple muscle fiber
shrinkage, death of muscle cells and/or degeneration of motor innervation. In addition, the biochemical process that
generates energy in muscle cells was almost totally absent. The progressive atrophy of certain muscles in
microgravity is the focus of this study, which compares the atrophy rates of muscles used primarily to oppose
gravity with those muscles used for movement.

Investigators will examine muscle tissues of flight and ground- control rodents to look for the shrinkage or death of
muscle cells, breakdown of muscle fibers or degeneration of motor nerves. Scientists also hope to discover the
chemical basis for atrophy by analyzing the concentration of enzymes that facilitate the breakdown of proteins
within cells.
 GET AWAY SPECIAL EXPERIMENTS
NASA's Get Away Special (GAS) program's goal is to provide access to space to everyone by offering an
inexpensive way for individuals and organizations, both private and public of all countries, to send scientific
research and development experiments on board a Space Shuttle for a modest fee on a space- available basis.

The GAS bridge, capable of holding a maximum of 12 canisters (or cans), fits across the payload bay of the orbiter
and offers a convenient and economic way of flying several canisters simultaneously.

To date, 55 GAS cans have flown on 15 missions. The GAS program began in 1982 and is managed by Goddard
Space Flight Center, Greenbelt, MD. Clarke Prouty is GAS project manager and Larry Thomas is Technical liaison
officer. The 12 GAS experiments on STS-40 are:

(G-021) Solid State Microaccelerometer Experiment

This experiment, sponsored by the European Space Agency (ESA), is part of ESA's In-Orbit Technology
Demonstration Program, which makes use of flight opportunities available on European and American carriers to fly
technology experiments.

The objective of the experiment is to test a new kind of very sensitive, highly miniaturized accelerometers, intended
for applications on a number of ESA space missions. Using a block of silicon material etched to create a frame with
a mass suspended on two beams, the experiment was devised to subject accelerometers to known vibration stimuli
while in the microgravity environment of the Shuttle orbit.

As a result of the extreme sensitivity of the accelerometers, noise created by the crew or Shuttle systems could
reduced the quality of the measurements. Because of this, the crew will switch on the experiment prior to a sleep
period. The experiment will work autonomously and will last about 3 hours. After the sleep period, the crew will
switch it off again.

The payload was designed and built by two Swiss companies, Compagnie Industrielle Radioelectrique S.A. and
Centre Suisse D'Elecronique et de Microtechnique S.A. The NASA technical manager (NTM) is Richard Hoffman.

(G-052) Experiment In Crystal Growth

This experiment was designed to grow crystals of gallium arsenide (GaAs). GaAs is a versatile electronic material
used in high speed electronics and opto-electronics.

The payload will grow two selenium-doped GaAs crystals. The crystals will be 1 inch in diameter by 3.5 inches long
and will be grown using a gradient freeze growth technique. Growth of the two crystals in space is part of a
comprehensive research program to systematically investigate the effect of gravity-driven fluid flow on GaAs
crystal growth.

The payload was designed and constructed at GTE Laboratories in Waltham, Mass., and is jointly sponsored by
GTE, NASA's Lewis Research Center, Cleveland, Ohio, and the U.S. Air Force Wright Research and Development
Center Materials Laboratory, Dayton, Ohio. Scientists from each research institution will contribute to
characterization of the space-grown crystals. The NTM is Dave Peters.

(G-091) Orbital Ball Bearing Experiment

A team of researchers from California State University, Northridge (CSUN) have built an experiment apparatus
called the Orbital Ball Bearing Experiment (OBBEX) to test the effects of melting cylindrical metal pellets in
microgravity. If successful, this experiment may produce a type of ball bearing which has never before been built.
One of the goals of the OBBEX experiment is to create the world's first seamless, hollow ball bearing. The hollow
characteristic of the ball can improve the service life rating of a ball bearing. This permits higher speeds and higher
load applications and may reduce the friction encountered in normal operation.

With faculty support, the OBBEX was designed and built as part of a senior year design project at California State
University, Northridge. Funding for the experiment was provided by two Southern California companies: Moore
Industries Inc., a manufacturer of industrial control systems, and Industrial Tektonics, Inc., a specialty bearing
manufacturer. Additional funding was supplied by the Aerospace Corporation, The CSUN Foundation and several
individuals. The NTM is Don Carson.

(G-105) In-Space Commercial Processing

Scientists at the University of Alabama in Huntsville (UAH) will use five experiments to study possible commercial
in-space processing opportunities. Those experiments and another in cosmic ray research are co-sponsored by
UAH's Consortium for Materials Development in Space and the U.S. Space and Rocket Center in Huntsville.

While Columbia is in orbit, two experiment packages in the canister will process organic films and crystals that
might be used in optical communications and computers. Another will electroplate metals to study special catalytic
or reactory properties, or resistance to corrosion. A fourth experiment will study technology used to refine and
process organic materials, such as medical samples.

The fifth UAH experiment will collect cosmic ray interactions on film emulsion while also helping scientists assess
materials that may be used in future massive cosmic ray detectors to be flown aboard the Shuttle or Space Station
Freedom or to determine exposure to energetic particles on Earth.

The sixth experiment is provided by the U.S. Space and Rocket Center, a state-owned, space science museum. It will
study the effects of cosmic radiation on the chromosomes and genes of a common yeast. The NTM is Larry Thomas.

(G-286) Foamed Ultralight Metals

The scientific aim of this payload is to demonstrate the feasibility of producing, in orbit, foams of ultralight metals
for possible application as shock-absorbing panel-backing to improve the shielding of both manned and unmanned
vehicles and satellites, including Space Station Freedom, against hypervelocity impacts either from micrometeoroids
or orbiting debris.

The concept of using ultralight, reactive alloys in the space environment, where their reactivity is not an issue, offers
many advantages in the engineering of large-scale space structures. Similarly, the idea of using metal foams made
from such alloys as shock-absorbing backing to improve the effectiveness of satellite armor may offer substantial
benefits in the design of Space Station Freedom.

The payload was built at Duke University in the Department of Mechanical Engineering and Materials Science. The
project was supported by Omni Magazine, which offered the canister as part of a national contest in 1983, and by
the School of Engineering in subsequent years. The NTM is Don Carson.

(G-405) Chemical Precipitate Formation

This payload will return data concerning the formation of six insoluble inorganic chemical precipitates. The
experiment will investigate the rate of formation and terminal size of precipitate particles when the growth is not
impaired by settling due to gravity.

The experiment is sponsored by the Frontiers of Science Foundation of Oklahoma, a private, non-profit organization
established to promote science education within Oklahoma, in conjunction with Louisiana Tech University. In 1983,
the foundation sponsored a contest among high school students to conceptualize an experiment which would fly
aboard the Shuttle. The revisions for the payload were performed at the Louisiana Tech University, where the
payload manager currently serves on the faculty in mechanical engineering.

After flight and analysis of data the payload will be donated and displayed at the Oklahoma Air and Space Museum
in Oklahoma City. The NTM is Larry Thomas.

(G-408) Five Microgravity Experiments

Five student experiments from the Worcester Polytechnic Institute are included in one GAS can. One will attempt to
grow large zeolite crystals. Another will study the behavior of fluids in microgravity. A third, the Environmental
Data Acquisition System, will record information about sound, light, temperature and pressure within the GAS can.
The fourth will measure the acceleration of the Shuttle along three axes with a high degree of precision. A fifth
experiment will study the fogging of film in space.

The experimental packages are sponsored by the MITRE Corp. Bedford, Mass. The NTM is Don Carson.

(G-451) Flower And Vegetable Seeds Exposure To Space

Sakana Seeds Corporation in Yokohama, Japan, and the Nissho Iwai American Corporation in New York, NY, will
jointly send 19 varieties of flower and vegetable seeds into space to determine how the unknown variables of
microgravity will affect seed growth. After the Shuttle lands and the seeds are recovered, the companies plan to
distribute the seeds widely to amateur growers. The NTM is Herbert Foster.

(G-455) Semiconductor Crystal Growth Experiment

This payload was developed to investigate the potential advantages of crystal growth under microgravity. There are
two experiments -- PbSnTe crystal growth from vapor and GaAs crystal growth from metallic solution. The payload
is sponsored by Fujitsu Limited in Kawasaki, Japan, and Nissho Iwai Corporation in Tokyo. The NTM is David
Shrewsberry.

(G-507) Orbiter Stability Experiment

This experiment, developed at Goddard Space Flight Center, will measure the Space Shuttle's spectrum of small
angular motions (or "jitter") produced by the operation of mechanical systems, thruster firings and human motions
during normal crew activity.

In addition to the vibration measurements that will be made, Goddard's GAS can also carries a passive experiment to
test the effects of radiation on photographic film. The experiment was developed and provided by Dr. Ernest
Hammond of Morgan State University, Baltimore, MD. The NTM is Neal Barthleme.

(G-616) The Effect Of Cosmic Radiation On Floppy Disks & Plant Seeds Exposure To Microgravity

This payload consists of two experiments. The first will investigate static computer memory (floppy disks) to
determine if cosmically charged particles will produce changes in data integrity or structure. The second will look
for changes in the physiology or growth of 38 different types of plant seeds. Each cultivator will be examined post-
flight in comparison with samples from the same seed lot, that remained on the Earth, for a wide variety of possible
effects or changes.

Several of the floppy disks contain programs developed by elementary school students. In addition, a large number
of plant seeds will be distributed to every elementary and junior high school student in the Redlands, Calif., Unified
School District, the sponsor of the experiment. The NTM is Charles Kim.
(G-486) Six Active Soldering Experiments
No information on this payload was provided by the sponsor, EDSYN, Inc. of Van Nuys, Calif. The NTM is
Bernard Karmilowicz.
 ORBITER EXPERIMENTS PROGRAM
The advent of operations of the Space Shuttle orbiter provided an opportunity for researchers to perform flight
experiments on a full-scale, lifting vehicle during atmospheric entry. To take advantage of this opportunity, NASA's
Office of Aeronautics, Exploration and Technology instituted the orbiter experiments (OEX) program in 1976.

The OEX program provides a mechanism for flight research experiments to be developed and flown aboard a Space
Shuttle orbiter. Since the program's inception, 13 experiments have been developed for flight. Principal investigators
for these experiments represent NASA's Langley and Ames Research Centers, Johnson Space Center and Goddard
Space Flight Center.

Seven OEX experiments will be flown on STS-40. Included among this group will be six experiments conceived by
Langley researchers and one experiment developed by Johnson.

Shuttle Entry Air Data System (SEADS)

The SEADS nosecap on the orbiter Columbia contains 14 penetration assemblies, each containing a small hole
through which the nosecap surface air pressure is sensed. Measurement of the pressure levels and distribution allows
post-flight determination of vehicle attitude and atmospheric density during entry. SEADS, which has flown on four
previous flights of Columbia, operates in an altitude range of 300,000 feet to landing. Paul M. Siemers III, Langley
Research Center, Hampton, Va., is the principal investigator.

Shuttle Upper Atmosphere Mass Spectrometer (SUMS)

The SUMS experiment complements SEADS by enabling measurement of atmospheric density above 300,000 feet.
SUMS samples air through a small hole on the lower surface of the vehicle just aft of the nosecap. It uses a mass
spectrometer operating as a pressure sensing device to measure atmospheric density in the high altitude, rarefied
flow regime where the pressure is too low for the use of ordinary pressure sensors. The mass spectrometer,
incorporated in the SUMS experiment, was spare equipment originally developed for the Viking Mars Lander.
SUMS was previously flown on STS-61C and STS-35. Robert C. Blanchard and Roy J. Duckett of Langley
Research Center are co-principal investigators.

Both SEADS and SUMS provide entry atmospheric environmental (density) information. These data, when
combined with vehicle motion data, are used to determine in-flight aerodynamic performance characteristics of the
orbiter.

Aerodynamic Coefficient Identification Package (ACIP)

The ACIP instrumentation includes three-axis sets of linear accelerometers, angular accelerometers and angular rate
gyros, which sense the orbiter's motions during flight. ACIP provides the vehicle motion data which is used in
conjunction with the SEADS environmental information for determination of aerodynamic characteristics below
about 300,000 feet altitude. The ACIP has flown on all flights of orbiters Columbia and Challenger. David B.
Kanipe, Johnson Space Center, Houston, is the ACIP principal investigator.

High Resolution Accelerometer Package (HiRAP)

This instrument is a three-axis set of highly sensitive accelerometers which measure vehicle motions during the high
altitude portion (above 300,000 feet) of entry. This instrument provides the companion vehicle motion data to be
used with the SUMS results. HiRAP has been flown on 12 previous missions of the orbiters Columbia and
Challenger. Robert C. Blanchard, Langley Research Center, is the HiRAP principal investigator.
Orbital Acceleration Research Experiment (OARE)

The Orbital Acceleration Research Experiment (OARE) complements the ACIP and HiRAP instruments by
extending the altitude range over which vehicle acceleration data can be obtained to orbital altitudes. Like the
HiRAP, the OARE instrument comprises a three- axis set of extremely sensitive linear accelerometers. The OARE
sensors are substantially more sensitive than the HiRAP sensors.

Because of their extreme measurement sensitivity, the OARE sensors cannot be adequately calibrated on the ground
(in a 1-g environment). Consequently, the sensors are mounted on a rotary calibration table which enables an
accurate instrument calibration to be performed on orbit.

The OARE instrument is installed for flight on a special mounting plate within the orbiter's payload bay. OARE data
are recorded on the mission payload recorder. This is the first flight for the OARE instrument. Principal investigator
is Robert C. Blanchard of Langley Research Center.

Shuttle Infrared Leeside Temperature Sensing (SILTS)

This experiment uses a scanning infrared radiometer located atop the vertical tail to collect infrared images of the
orbiter's leeside (upper) surfaces during entry, for the purpose of measuring the temperature distribution and the
aerodynamic heating environment. On two previous missions, the experiment obtained images of the left wing. For
STS-35 and STS-40, the experiment has been configured to obtain images of the upper fuselage. SILTS has flown
on four Columbia flights. David A. Throckmorton and E. Vincent Zoby of Langley Research Center are co-principal
investigators.

Aerothermal Instrumentation Package (AIP)

The AIP comprises some 125 measurements of aerodynamic surface temperature and pressure at discrete locations
on the upper surface of the orbiter's left wing and fuselage and the vertical tail. These sensors were originally part of
the development flight instrumentation system that flew aboard Columbia during its Orbital Flight Test missions
(STS-1 through 5). They have been reactivated through the use of an AIP- unique data handling system. Among
other applications, the AIP data provide "ground-truth" information for the SILTS experiment. The AIP has flown
on three previous Columbia flights. David A. Throckmorton, Langley Research Center, is principal investigator.
 STS-40 CREWMEMBERS

STS040-S-002 -- Five NASA astronauts and two scientists serving as payload specialists have been named to fly
aboard Columbia, Orbiter Vehicle (OV) 102, for NASA's STS-40 mission. Astronaut Bryan D. O'Connor (rear left)
is the mission commander, and Sidney M. Gutierrez (rear right) is the pilot. Others are (front, left to right) payload
specialists F. Drew Gaffney and Millie Hughes-Fulford; mission specialists M. Rhea Seddon, James P. Bagian, and
Tamara E. Jernigan (rear center). The primary payload for this flight is Spacelab Life Sciences 1 (SLS-1) (note the
model of the shuttle with the Spacelab module and related hardware depicted). The crewmembers are wearing
launch and entry suits (LESs). The crew insignia and the United States flag are displayed in the background.

No copyright is asserted for this photograph. If a recognizable person appears in the photo, use for commercial
purposes may infringe a right of privacy or publicity. It may not be used to state or imply the endorsement by NASA
or by any NASA employee of a commercial product, process or service, or used in any other manner that might
mislead. Accordingly, it is requested that if this photograph is used in advertising and other commercial promotion,
layout and copy be submitted to NASA prior to release.

PHOTO CREDIT: NASA or National Aeronautics and Space Administration.

 BIOGRAPHICAL DATA
MARINE CORPS COL. BRYAN D. O'CONNOR, 44, will serve as Commander of STS-40 and will be making
his second space flight. O'Connor, from Twentynine Palms, Calif., was selected as an astronaut in May 1980.

He graduated from Twentynine Palms High School in 1964, received a bachelor of science degree in engineering
from the U.S. Naval Academy in 1968 and received a master of science in aeronautical engineering from the
University of West Florida in 1970.

He was commissioned in the Marine Corps in 1968 and following several overseas assignments, graduated from the
Navy Test Pilot School and began duty as a test pilot at the Naval Air Test Center's Strike Test Directorate. He
served as project pilot for various very short take off and landing (VSTOL) research aircraft, including preliminary
evaluation of the YAV-88 advanced Harrier prototype.

After selection as an astronaut, he served as a T-38 chase pilot for STS-3 and as spacecraft communicator for STS-5
through STS-9. He then served as pilot of Atlantis on STS-61B from Nov. 26 through Dec. 3, 1985, during which
the crew deployed three communications satellites and conducted two Space Station assembly test spacewalks.
O'Connor has logged more than 165 hours in space and more than 4,100 hours flying time in jet aircraft.

AIR FORCE LT. COL. SIDNEY M. GUTIERREZ, 39, will serve as Pilot. Selected as an astronaut in 1984,
Gutierrez, from Albuquerque, NM, will be making his first space flight.

Gutierrez graduated from Valley High School, Albuquerque, in 1969, received a bachelor of science in aeronautical
engineering from the Air Force Academy in 1973 and received a master of arts in management from Webster
College in 1977.

He was a member of the Air Force Academy collegiate parachute team while in college with a master parachutist
rating and over 550 jumps. After graduating from the Air Force Academy, he was assigned as a T-38 instructor pilot
from 1975-1977 at Laughlin Air Force Base, Del Rio, Texas. He attended the Air Force Test Pilot School in 1981
and was assigned to the F-16 Falcon Combined Test Force upon graduation, where he stayed until joining NASA.

At NASA, his duties have included work in the Shuttle Avionics Integration Laboratory and as the lead astronaut for
Shuttle software development, verification and future requirements definition. He has logged more than 3,000 hours
flying time in 30 different types of aircraft, sailplanes and balloons.

JAMES P. BAGIAN, MD, 39, will serve as Mission Specialist 1 (MS1). Selected as an astronaut in 1980, Bagian is
from Philadelphia, Pa., and will be making his second space flight.

Bagian graduated from Central High School, Philadelphia, in 1969, received a bachelor of science in mechanical
engineering from Drexel University in 1973 and received a doctorate of medicine from Thomas Jefferson University
in 1977.

Bagian worked as a mechanical engineer at the Naval Air Test Center while pursuing his doctorate. Upon
graduation, he served a 1-year residency with the Geisinger Medical Center, Danville, Pa. Subsequently, he joined
NASA as a flight surgeon, concurrently completing studies at the Air Force Flight Surgeons School and School of
Aerospace Medicine, San Antonio, Texas. Bagian is a Lt. Col. in the Air Force Reserve.

After selection as an astronaut, Bagian worked in planning and providing emergency medical and rescue support for
the first six Shuttle flights. Bagian served as a mission specialist aboard Discovery on STS-29, March 13-18, 1989,
on which the crew deployed a tracking and data relay satellite, conducted a Space Station heat pipe radiator
experiment, two student experiments and a chromosome and plant cell division experiment.
 BIOGRAPHICAL DATA
TAMARA E. JERNIGAN, Ph.D., 32, will serve as Mission Specialist 2 (MS2). Selected as an astronaut in 1985,
Jernigan is from Santa Fe Springs, Calif., and will be making her first space flight.

Jernigan graduated from Santa Fe High School in 1977, received a bachelor of science in physics and a master of
science in engineering science from Stanford University in 1981 and 1983, respectively, received a master of
science in astronomy from the University of California-Berkley in 1985 and received a doctorate in space physics
and astronomy from Rice University, Houston, Texas, in 1988. After selection as an astronaut, Jernigan worked as a
spacecraft communicator in Mission Control for five Shuttle flights.

MARGARET RHEA SEDDON, MD, 43, will serve as Mission Specialist 3 (MS3). Selected as an astronaut in
1978, Seddon is from Murfreesboro, TN, and will be making her second space flight.

Seddon graduated from Central High School, Murfreesboro, in 1965, received a bachelor of arts in physiology from
the University of California-Berkley in 1970 and received a doctorate of medicine from the University of Tennessee
College of Medicine in 1973. She completed a surgical internship and 3 years of general surgery residency in
Memphis following graduation.

Seddon served as a Mission Specialist aboard Discovery on STS-51D, April 12-19, 1985. During the flight, the crew
deployed three communications satellites and conducted the first unscheduled Shuttle spacewalk to correct a
malfunction of one satellite. Seddon has logged 168 hours of space flight.

FRANCIS ANDREW GAFFNEY, MD, 44, will serve as Payload Specialist 1 (PS1). Gaffney will be making his
first space flight and his hometown is Carlsbad, NM.

Gaffney graduated from Carlsbad High School in 1964, received a bachelor of arts from the University of
California-Berkley in 1968, received a doctor of medicine degree from the University of New Mexico in 1972 and
received a fellowship in cardiology from the University of Texas in 1975.

He completed a 3-year medical internship and residency at Cleveland Metropolitan General Hospital, Cleveland,
Ohio, in 1975, and went on to receive a fellowship in cardiology at the University of Texas' Southwestern Medical
Center in Dallas, becoming a faculty associate and an assistant professor of medicine there in 1979. From 1979-
1987, he served as assistant director of echocardiography at Parkland Memorial Hospital, Dallas.

Gaffney served as a visiting senior scientist with NASA from 1987-1989. He is a co-investigator on an experiment
aboard STS-40 that studies human cardiovascular adaptation to space flight.

MILLIE HUGHES-FULFORD, Ph.D., 46, will serve as Payload Specialist 2 (PS2). Hughes-Fulford, from
Mineral Wells, Texas, will be making her first space flight.

Hughes-Fulford graduated from Mineral Wells High School in 1972, received a bachelor of science in chemistry
from Tarleton State University, Stephenville, Texas and received a doctorate in chemistry from Texas Woman's
University, Denton, in 1972.

Since 1973, she has worked at the University of California and the Veterans Administration Medical Center, doing
extensive research on cholesterol metabolism, cell differentiation, DNA synthesis and cell growth. After assignment
by NASA, she has continued her research, concentrating on a study of cellular and molecular mechanisms for bone
formation as it relates to space flight.
 STS-40 MISSION MANAGEMENT
NASA HEADQUARTERS, WASHINGTON, DC

Richard H. Truly Administrator

J. R. Thompson Deputy Administrator
Dr. William B. Lenoir Associate Administrator, Office of Space Flight
Robert L. Crippen Director, Space Shuttle
Leonard S. Nicholson Deputy Director, Space Shuttle (Program)
Brewster Shaw Deputy Director, Space Shuttle (Operations)
Dr. Lennard A. Fisk Associate Administrator, Space Science and Applications
Alphonso V. Diaz Deputy Associate Administrator, Space Science and Applications
Dr. Arnauld Nicogossian Director, Life Sciences Division
Dr. Ronald J. White Program Scientist
Robert Benson Director, Flight Systems Division
Gary McCollum Program Manager, SLS Mission

KENNEDY SPACE CENTER, FL

Forrest S. McCartney Director

Jay Honeycutt Director, Shuttle Management and Operations
Robert B. Sieck Launch Director
John T. Conway Director, Payload Management and Operations
JoAnn H. Morgan Director, Payload Project Management
Mike Kinnan STS-40 Payload Manager

MARSHALL SPACE FLIGHT CENTER, HUNTSVILLE, AL

Thomas J. Lee Director

Dr. J. Wayne Littles Deputy Director
G. Porter Bridwell Manager, Shuttle Projects Office
Dr. George F. McDonough Director, Science and Engineering
Alexander A. McCool Director, Safety and Mission Assurance
Victor Keith Henson Manager, Solid Rocket Motor Project
Cary H. Rutland Manager, Solid Rocket Booster Project
Jerry W. Smelser Manager, Space Shuttle Main Engine Project
Gerald C. Ladner Manager, External Tank Project

STENNIS SPACE CENTER, BAY ST. LOUIS, MS

Roy S. Estess Director

Gerald W. Smith Deputy Director
J. Harry Guin Director, Propulsion Test Operations
JOHNSON SPACE CENTER, HOUSTON, TX

Aaron Cohen Director

Paul J. Weitz Deputy Director
Daniel Germany Manager, Orbiter and GFE Projects
Paul J. Weitz Acting Director, Flight Crew Operations
Eugene F. Kranz Director, Mission Operations
Henry O. Pohl Director, Engineering
Charles S. Harlan Director, Safety, Reliability and Quality Assurance

LANGLEY RESEARCH CENTER, HAMPTON, VA

Richard H. Petersen Director

W. Ray Hook Director for Space
William H. Piland Chief, Space Systems Division
Delma C. Freeman Jr. Assistant Chief, Space Systems Division

AMES RESEARCH CENTER, MOFFETT FIELD, CA

Dr. Dale L. Compton Director

Victor L. Peterson Deputy Director
Dr. Steven A. Hawley Associate Director
Dr. Joseph C. Sharp Director, Space Research

AMES DRYDEN FLIGHT RESEARCH FACILITY, EDWARDS, CA

Kenneth J. Szalai Director

T. G. Ayers Deputy Director
James R. Phelps Chief, Shuttle Support Office