Bleomyci

Bleomycin is a chemotherapy drug that is given as a treatment for some types of

cancer, including testicular cancer, lymphoma and cancers of the head and neck.
Sweetman et al. Martindale: The Complete Drug Reference. 36th edition. 2009.
Pharmaceutical Press.

Bleomycin is commonly given alongside other chemotherapy drugs as part of a

combination regimen . Ed. Perry. Lippincott, Williams and Wilkins The
Chemotherapy Source Book. 4th edition. 2007. Bleomycin is a powder that is
dissolved to form a colourless fluid.

Temozolomide
Temozolomide is a chemotherapy drug that is given as a treatment for some types
of cancer . It is most commonly used to treat a type of brain tumour known as a
glioma. Eds. Sweetman et al. Martindale: The Complete Drug Reference 36th edition. 2009.
Pharmaceutical Press.

Capecitabine (Xeloda®)
Capecitabine is a chemotherapy drug that is given as a treatment for many types of cancer, includ
colon, rectum, breast, stomach, pancreas and gullet (oesophagus). Ed. Perry. Lippincott,
Williams and Wilkins The Chemotherapy Source Book. 4th edition. 2007.

Cisplatin
Cisplatin is a chemotherapy drug that is given as a treatment for some types of cancer. It's most
commonly used to treat testicular, bladder, lung, gullet (oesophagus) , stomach and ovarian
cancers. Cisplatin is a colourless fluid. Cisplatin is sometimes given alongside other
chemotherapy drugs as part of a combination regimen

Cyclophosphamide
Cyclophosphamide is a chemotherapy drug that is given as a treatment for many types of cancer.
It's most commonly used to treat lymphomas; cancers of the ovary , breast and bladder; and
chronic lymphocytic leukaemia (CLL). Cyclophosphamide is a powder, which dissolves to form
a colourlesss fluid

Cytarabine
Cytarabine is a chemotherapy drug that is given as a treatment for some types of cancer. It is
sometimes called Ara C or cytosine arabinoside. Cytarabine is most commonly used to treat
acute myeloid leukaemia (AML Cytarabine is a colourless fluid.

Dacarbazine (DTIC)
Dacarbazine is a chemotherapy drug that is given as a treatment for some types of cancer. It's
most commonly used to treat melanoma, Hodgkin lymphoma and soft tissue sarcomas. This
information describes dacarbazine, how it is given and some of its possible side effects.
Dacarbazine is a pale yellow liquid.

Daunorubicin
Daunorubicin is a chemotherapy drug that is given as a treatment for some
types of cancer. It's most commonly used to treat acute myeloid leukaemia
(AML) and acute lymphocytic leukaemia (ALL). Daunorubicin is a red fluid.

Docetaxel (Taxotere®)
Docetaxel is a chemotherapy drug that is given as a treatment for some types of cancer. It is also
known as Taxotere®. It is most commonly used to treat breast cancer, prostate cancer and non-
small cell lung cancer, but may be used for many other types of cancer. Docetaxel is a
yellow/brown liquid, which forms a clear solution when diluted.

Etoposide (VP-16, Etopophos®, Vepesid®)

Etoposide is a chemotherapy drug that is given as a treatment for some types of cancer. It's most
commonly used to treat lung , ovarian and testicular cancer.Etoposide is a colourless fluid. It is
also available as pale pink capsules of 50mg and 100mg.

Fludarabine (Fludara®)
Fludarabine is a chemotherapy drug that is given as a treatment for some types of cancer. It's
most commonly used to treat chronic lymphocytic leukaemia (CLL).Fludarabine is a clear fluid
after being dissolved from powder

Mitomycin
Mitomycin is a chemotherapy drug that is given as a treatment for several different types of
cancer, including breast , stomach , gullet (oesophagus) and bladder cancers.Mitomycin is a
purple fluid.

Oxaliplatin (Eloxatin®)
Oxaliplatin is a chemotherapy drug that is given as a treatment for some types of cancer. It is
most commonly used to treat cancer of the large bowel and gullet (oesophagus) . Oxaliplatin is a
colourless fluid.

Paclitaxel (Taxol®)
Paclitaxel is a chemotherapy drug that is given as a treatment for some types of cancer. It's also
known as Taxol. It is mainly used to treat ovarian , breast and non-small cell lung
cancer.Paclitaxel is a colourless fluid.

Vinblastine (Velbe®)
Vinblastine is a chemotherapy drug that is given as a treatment for some types of cancer. It's
mainly used to treat bladder cancer, but can also be used to treat other cancers, including
lymphoma and Kaposi's sarcoma.Vinblastine is a colourless fluid.

Cancer is one of the most widespread and feared diseases in the Western world today -
feared largely because it is known to be difficult to cure. The main reason for this
difficulty is that cancer results from the uncontrolled multiplication of subtly modified
normal human cells. One of the main methods of modern cancer treatment is drug
therapy(chemotherapy Denny, William A.; New Directions in Cancer Chemotherapy; Chemistry
in NewZealand/July 1995
Chemotherapy is the systemic (whole body) treatment of cancer with anticancer
drugs. Hirsch J (September 2006). "An anniversary for cancer chemotherapy". JAMA
296 (12): 1518–20.

Cancer is a group of diseases characterized by uncontrolled cell division leading to growth of abnormal
tissue. Anticancer drugs destroy cancer cells by stopping them from growing or multiplying.

Anticancer, or antineoplastic, drugs are used to treat malignancies, or cancerous

growths. Drug therapy may be used alone, or in combination with other treatments
such as surgery or radiation therapy.
 Anti Cancer Drugs
Common Side
Generic (Brand Name) Clinical Uses
Effects To Drug
Altretamine (Hexalen) Treatment of Bone marrow
advanced ovarian depression, nausea
cancer and vomiting
Asparaginase (Elspar) Commonly used in Liver, kidney,
combination with pancreas, CNS
other drugs; refrac- abnormalities,
tory acute lymphocy-
tic leukemia
Bleomycin (Blenoxane) Lymphomas, Hair loss, stomatitis,
Hodgkin's disease, pulmonary toxicity,
testicular cancer hyperpigmentation
of skin
Busulfan (Myleran) Chronic granulocytic Bone marrow
leukemia depression,
pulmonary toxicity
Carboplatin (Paraplatin) Pallilation of ovarian Bone marrow
cancer depression, nausea
and vomiting
Carmustine Hodgkin's disease, Bone marrow
brain tumors, multi- depression, nausea
ple myeloma, malig- and vomiting, toxic damage to liver
nant melonoma
Chlorambucil (Leukeran) Chronic lymphocytic Bone marrow
leukemia, non- depression, excess
Hodgkin's uric acid in blood
lymphomas, breast
and ovarian cancer
Cisplatin (Platinol) Treatment of bladder, Renal toxicity and
ovarian, ototoxicity
uterine, testicular,
head and neck
cancers
Cladribine (Leustatin) Hairy cell leukemia Bone marrow
depression, nausea
and vomiting, fever
Cyclophosphamide Hodgkin's disease, Bone marrow
(Cytoxan) non-Hodgkin's lym- depression, hair loss,
phomas, neuroblas- nausea and vomiting,
toma. Often used inflammation of the
with other drugs for bladder
breast, ovarian, and
lung cancers; acute
 Anti Cancer Drugs
Common Side
Generic (Brand Name) Clinical Uses
Effects To Drug
Altretamine (Hexalen) Treatment of Bone marrow
advanced ovarian depression, nausea
cancer and vomiting
Asparaginase (Elspar) Commonly used in Liver, kidney,
combination with pancreas, CNS
other drugs; refrac- abnormalities,
tory acute lymphocy-
tic leukemia
lymphoblastic leuke-
mia in children; mul-
tiple myeloma
Cytarabine (Cytosar-U) Leukemias occurring Bone marrow
in adults and children depression, nausea
and vomiting,
diarrhea, stomatitis
Dacarbazine (DTIC- Hodgkin's disease, Bone marrow
Dome) malignant melanoma depression, nausea
and vomiting
Diethylstilbestrol (DES) Breast cancer in Hair loss, nausea and
(Stilbestrol) post-menopausal vomiting, edema,
women, prostate excess calcium in
cancer blood; feminizing
effects in men
Ethinyl Advanced breast Excess calcium in
estradiol (Estinyl) cancer in post- blood, anorexia,
menopausal women, edema, nausea and
prostate cancer vomiting; feminizing
effects in men
Etoposide (VePesid) Acute leukemias, Bone marrow
lymphomas, testicu- depression, nausea
lar cancer and vomiting, hair loss
Anti Cancer Drugs (continued)
Common Side
Generic (Brand Name) Clinical Uses
Effects to Drug
Mitomycin (Mutamycin) Bladder, breast, Bone marrow
colon, lung, depression, nausea
pancreas, rectum and vomiting,
cancers, head and diarrhea, stomatitis,
neck cancer, malig- possible tissue
nant melanoma damage
Mitotane (Lysodren) Cancer of the adrenal Damage to adrenal
 Anti Cancer Drugs
Common Side
Generic (Brand Name) Clinical Uses
Effects To Drug
Altretamine (Hexalen) Treatment of Bone marrow
advanced ovarian depression, nausea
cancer and vomiting
Asparaginase (Elspar) Commonly used in Liver, kidney,
combination with pancreas, CNS
other drugs; refrac- abnormalities,
tory acute lymphocy-
tic leukemia
cortex (inoperable) cortex, nausea,
anorexia
Mitoxantrone (Novantrone) Acute nonlymphocy- Cardiac arrhythmias,
tic leukemia labored breating,
nausea and vomiting,
diarrhea, fever,
congestive heart
failure
Paclitaxel (Taxol) Advanced ovarian Bone marrow
cancer depression, hair loss,
nausea and vomiting,
hypotension, allergic
reactions, slow heart
action, muscle and
joint pain
Pentastatin (Nipent) Hairy cell leukemia Bone marrow
unresponsive to depression, fever,
alpha-interferon skin rash, liver
damage, nausea and
vomiting
Pipobroman (Vercyte) Chronic granulocytic Bone marrow
leukemia depression
Plicamycin (Mithracin) Testucular tumors Toxicity/damage
to bone marrow,
kidneys, and liver
Prednisone (Meticorten) Used in adjunct ther- May be toxic to all
apy for palliation of body systems
symptoms in lympho-
mas, acute leukemia
Hodgkin's disease
Procarbazine (Matulane) Hodgkin's disease Bone marrow
depression, nausea
and vomiting
 Anti Cancer Drugs
Common Side
Generic (Brand Name) Clinical Uses
Effects To Drug
Altretamine (Hexalen) Treatment of Bone marrow
advanced ovarian depression, nausea
cancer and vomiting
Asparaginase (Elspar) Commonly used in Liver, kidney,
combination with pancreas, CNS
other drugs; refrac- abnormalities,
tory acute lymphocy-
tic leukemia
Streptozocin (Zanosar) Islet cell carcinoma of Nausea and vomiting,
pancreas toxicity to kidneys
Tamoxifen (Nolvadex) Advanced breast can- Nausea and vomiting,
cer in post ocular toxicity, hot
menopausal flashes
Teniposide (Vumon) Acute lymphocytic See Etoposide
leukemia in children
Vinblastine (Velban) Breast cancer, Bone marrow
Hodgkin's disease, depression,
metastatic testicular neurotoxicity
cancer
Vincristine (Oncovin) Acute leukemia, Constipation,
Hodgkin's disease, neurotoxicity,
lymphomas possible tissue
necrosis