Professional Documents
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Format For Instruction Plan [for Courses with Lectures and Labs
Course No PHR112
Text Book:
1 Chatwal G. R. Pharmaceutical Chemistry Inorganic Vol 1, Himalaya Publishing House, New Delhi.
2 Block, J.H., Roche, E., Soine, T.O. and Wilson, C.O. Inorganic Medicinal and Pharmaceutical Chemistry, Varghese Publishing House, Bombay
Other Reading Sr No Jouranls atricles as compulsary readings (specific articles, Complete reference)
Relevant Websites Sr. No. (Web adress) (only if relevant to the courses) 3 www.chemguide.co.uk/physical/acidbaseeqia/theories.html Salient Features Theories of acids and bases
Part 1
Week 1 Lecture 1 Pharmaceutical aids & necessities: various concepts ->Reference :1,6 of acids and bases, relative strength of acid and ->Reference :2,4 base, pH scale and calculation of pH, Approved for Autumn Session 2011-12
Week 1
Lecture 2
Acids: preparation, properties and uses of boric acid, hydrochloric acid, dilute hydrochloric acid, sulphuric acid, phosphoric acid, dilute phosphoric acid, Bases: preparation, properties and uses of strong and dilute ammonia solution, sodium hydroxide and calcium hydroxide Buffers: definition, types and properties of buffer solution Anti-oxidants: preparation, properties and uses of Hypophosphorous acid, sulphur dioxide, sodium bisulphite, sodium metabisulphite, sodium thiosulphate, Tableting agents: brief introduction to diluents, granulating agents, binding agents, disintegrating agents, lubricants Suspending agents: bentonite, colloidal silica, aluminium sterate Preservative and filter aids: kieselghur, fuller earth Gastrointestinal agents: acidifying agents: dilute hydrochloric acid antacids: definition, ideal requirements and classification of antacids Preparation, properties and uses of sodium bicarbonate, aluminium hydroxide gel, aluminium phosphate gel
Lecture 3
Week 2
Lecture 4 Lecture 5
Lecture 6
->Reference :1,20 ->Reference :2,12 ->Reference :1,20 ->Reference :2,12 ->Reference :1,20 ->Reference :1,8 ->Reference :2,8
Week 3
Week 4
Lecture 10
Part 2
Week 4 Lecture 11 Preparation, properties and uses of calcium carbonate, tribasic calcium phosphate, magnesium carbonate, magnesium oxide, milk of magnesia, magnesium hydroxide Protective and adsorbents: bismuth subcarbonate, bismuth subnitrate, bismuth subgallate, milk of bismuth Cathartics: classification and mechanism of action Preparation, properties and uses of milk of magnesia, magnesium hydroxide, magnesium sulphate, sodium phosphate, sodium potassium tartrate, potassium bitartrate Approved for Autumn Session 2011-12 ->Reference :1,8 ->Reference :2,8 ->Reference :1,8 ->Reference :2,8
Lecture 12
Week 5
Lecture 13 Lecture 14
Week 5
Lecture 15
Major intracellular and extracellular electrolytes, major physiological ions, electrolytes used in replacement therapy, sodium chloride, potassium chloride
Week 6
Lecture 16
Physiological acid-base balance, electrolytes used ->Reference :1,13 in acid base therapy, electrolyte combination ->Reference :2,5 therapy, sodium acetate, potassium acetate, sodium bicarbonate, sodium citrate, potassium citrate, sodium lactate Essential and trace elements of pharmaceutical importance, mineral supplements Haematinics: ferric ammonium citrate, ferrous gluconate, ferrous fumarate, ferrous succinate, ferrous sulphate Topical agents including protective: talc, calamine, zinc oxide, zinc stearate Astringents: alum, aluminium chloride, aluminium sulphate, zinc chloride, zinc sulphate Antimicrobials: mechanism of action, hydrogen peroxide, potassium permanganate, chlorinated lime, iodine, solution of iodine, povidone-iodine ->Reference :1,14 ->Reference :2,6 ->Reference :1,9 ->Reference :2,9
Lecture 17 Lecture 18
Week 7
MID-TERM Part 3
Week 8 Lecture 22 Lecture 23 Lecture 24 Week 9 Lecture 25 Lecture 26 Lecture 27 Week 10 Lecture 28 Dental products: anti-caries agents: sodium fluoride, ->Reference :1,10 sodium monofluorophosphate, stannous fluoride, ->Reference :2,10 Dentrifrices: calcium carbonate, dibasic calcium phosphate, calcium phosphate Dentrifrices: , sodium metaphosphate, strontium chloride Polishing agents, desensitising agents, mouth wash ->Reference :1,10 ->Reference :2,10 Inhalants: oxygen, carbon dioxide Inhalants: nitrous oxide, helium, nitrogen Respiratory stimulants: ammonium carbonate ->Reference :1,11 ->Reference :2,12 ->Reference :1,11 ->Reference :2,12
Part 4
Week 10 Lecture 29 Lecture 30 Week 11 Lecture 31 Complexing agents, their theoretical considerations ->Reference :2,12 and official products. Radiopharmaceuticals: nomenclature, types of radionuclides, nature of radiation Units of radioactivity, measurement of radioactivity: Gas filled detectors (Ionisation chamber, proportional countersG-M counters) Measurement of radioactivity: Scintillation detector (Inorganic scintillator, organic scintillator, semiconductor detectors, autoradiography) Handling and storage of radioactive material, Clinical applications Expectorants and emetics: ammonium chloride, potassium iodide, antimony potassium tartrate Poisons: types and routes of poisoning Antidotes: types of antidotes, treatment of heavy metal and cyanide poisoning ->Reference :1,12 ->Reference :2,12 ->Reference :1,18 ->Reference :2,12 ->Reference :1,17 ->Reference :2,11 ->Reference :1,17 ->Reference :2,11
Lecture 32
Spill Over
Week 13 Lecture 37 Lecture 38 Buffers: definition, types and properties of buffer solution measurement of radioactivity: Gas filled detectors (Ionisation chamber, proportional countersG-M counters) ->Reference :1,6 ->Reference :2,4 ->Reference :1,17 ->Reference :2,11
*Each experiment of the lab will be evaluated using following relative scheme:
Component J/E WR VIVA % of Marks 20 50 30
List of experiments :Lecture Number Experimental work 1 Experimental work 2 Experimental work 3 Experimental work 4 Experimental work 5 Experimental work 6 Lecture Topic Identification test of Potassium iodide. Identification test of sodium bicarbonate. To perform limit test of chloride in given sample. Identification test and assay of Boric Acid. Identification test of Ammonium chloride. To perform limit test of sulphate in given sample. Pedagogical Tools Or Equipment Planned lab Manual
Measuring cylinder, conical flask , Pipette, Test tube, Not Applicable holder, test tube stand Measuring cylinder, conical flask , Pipette, Test tube, Not Applicable holder, test tube stand Nesseler cylinder, glass rod, measuring cylinder Measuring cylinder, conical flask, Pipette, Test tube, holder, test tube stand, burette Measuring cylinder, conical flask, Pipette, Test tube, holder, test tube stand Nesseler cylinder, glass rod, measuring cylinder Not Applicable Not Applicable Not Applicable Not Applicable
Mid Term
Experimental work 7 Experimental work 8 Experimental work 9 Experimental work 10 Experimental work 11 To perform the limit test of Iron in given sample. Identification test of Hydrogen peroxide. To perform the assay of Sodium hydroxide. To perform the assay of Sodium Bicarbonate. Identification test of cations (sodium, potassium and ammonium) and anions(iodide, bicarbonate and chloride) Nesseler cylinder, glass rod, measuring cylinder Measuring cylinder, conical flask, Pipette, Test tube, holder, test tube stand Measuring cylinder, conical flask, Pipette, burette Measuring cylinder, conical flask, Pipette, burette Measuring cylinder, conical flask, Pipette, Test tube, holder, test tube stand Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable
Spill Over
Experimental work 12 Experimental work 13 To perform the assay of Sodium Bicarbonate. To perform the assay of Sodium hydroxide. Measuring cylinder, conical flask, Pipette, burette Measuring cylinder, conical flask , Pipette, burette Not Applicable Not Applicable