Eugene B. Frolov, PhD 9459 Fairgrove Lane, # 201, San Diego, CA, 92129.

Phone: home: (858) 4842052; cell: (858) 9224948 ef11a3516@westpost.net Authorized to work in USA; permanent resident since 2008 _______________________________________________________________________ OBJECTIVE: Seeking a position of a Medicinal / Synthetic Organic Chemist SUMMARY: I have 25 years of progressive experience in organic chemistry, and for the last 10 years, I have been for U.S. companies in the field of synthesis of pharmaceu tical and medicinal chemistry compounds. I specialize in multi-step synthesis of biologically active compounds largely small heterocyclic and poly-functional mo lecules. My expertise includes design and optimization of synthetic routes and p rocedures; unique hands-on laboratory skills and experience in synthesis, isolat ion, chromatographic purification and structure identification of organic molecu les; extensive knowledge of modern synthetic approaches and chemical modificatio ns. I am able to handle many simultaneous projects and supervise associate chemi sts. Creative, hard-working and enthusiastic chemist, solid performer, recognize d for high productivity. TECHNICAL EXPERIENCE: PhD in organic chemistry, with particular expertise in the synthesis of heterocy clic, poly-functional, conjugated and polycyclic molecules on scales ranging fro m several mg to KGs. Broad knowledge in diverse areas of synthetic organic chemi stry including heterocyclic and organometallic chemistry. Proficient in designi ng, planning, validating and executing multi step organic synthesis. Broad exper ience in modern functional group transformations and protection/deprotection mod ifications. Parallel synthesis, stereoselective synthesis, glove box chemistry, high pressure reactions. Extensive hands-on experience in modern techniques for isolation, purification, extractive separation, precipitation/crystallization an d structure identification, including thin-layer, flash, column, gel and ion-exc hange chromatography, LCMS, HPLC, 1H and 13C NMR, IR-, UV-visible and mass-spect roscopy. Experience in scale-up (50 L) process development and optimizations. Fa miliar with the chemical literature. Strong computer skills: MS Office (Word, Ex cel, Power Point, ISIS, ChemDraw, Beilstein Reaxys, MOPAC. EXPERIENCE: Nanosyn Inc, San Diego, CA, USA, Feb. 2008 a" May. 2010. Senior Research Scientist: custom organic synthesis, process chemistry, medicina l chemistry. Multi-step customer syntheses of compounds of medicinal chemistry i nterest in mg- and KG-scale; process development; design and optimization of syn thetic routes and procedures. ChemDiv Inc, San Diego, CA, USA, Jan. 2001 a" Jan. 2008. Senior Research Scientist: medicinal chemistry. Design and production of multiple small molecule heterocyclic libraries for over 20 ChemDiv clients, including several world-renowned pharmaceutical companies. Participated as a key chemist in several ChemDiv medicinal chemistry collaborati ons including Dendreon-ChemDiv small molecule effort to synthesize a number of n ovel heterocyclic compounds with high anticancer activity. A principal chemist i n a three-year internal ChemDiv project aimed synthesis and biological evaluatio n of a number of novel structural analogues of DIMEBON: design and optimization of novel synthetic routes to small heterocyclic molecules of g-carboline series

with a wide scope of biological activity including potential therapeutic applica tions for treatment of Alzheimer and other neurodegenerative diseases. Newcastle University, UK, 1992-1993. Distinguished Visiting Fellow Synthesis of substituted pyridine and carbazole derivatives. Study of their appl ications in organic geochemistry as a amolecular odometersa for tracing lateral petroleum migration. A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Science, Russia, 1980-2001, Research Associate, Senior Researcher, Group Leader Synthesis and research of molecular structure of petroleum naturally occurring g eo-molecules (with emphases on in crude oil olefins, three-terpenoid acids, car bazole derivatives) required as biomarkers in geochemical studies. Discovery and research of radiogenic olefins in crude oil. EDUCATION: PhD in Organic Chemistry: Department of Chemistry, Lomonosov Moscow State Univer sity, Russia, 1980 BS/MS in Organic Chemistry: Department of Chemistry, Lomonosov Moscow State Univ ersity, 1976 PROFESSIONAL AWARDS AND HONORS: 1994-1995 Grant from the International Science Foundation; Principal Investigato r. 1999 The Zelinsky Award from the Russian Academy of Sciences for outstanding res earch in the field of organic and petroleum chemistry. PATENTS, PUBLICATIONS, AND PRESENTATIONS: Three patents, two reviews, 53 publications and presentations in refereed journa ls and prestigious conferences. REFERENCES: Excellent professional references are available upon request.