DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ROSUVASTATIN IN TABLET DOSAGE FORM A Dissertation submitted to University of Pune,

(M.S.)
In Partial fulfillment of the Degree of

Bachelor of Pharmacy

SUBMITTED BY
MR. RISHIKESH .D.CHAKOR (Third Year B. Pharm) PRN No. 57901671E

UNDER THE GUIDANCE OF

ASSISTANT PROF. (MR) V. P. CHOUDHARI
M. Pharm.

Pharmaceutical Analysis and Quality Assurance Department

MAEERS, MAHARASHTRA INSTITUTE OF PHARMACY PUNE - 411038 2009 - 2010

FORWARDING LETTER has completed the project entitled DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ROSUVASTATIN
MR.RISHIKESH.D.CHAKOR
IN TABLET DOSAGE FORM.

CHOUDHARI

under supervision of ASSISTANT PROF. (MR) V. P. In partial fulfillment of requirement for degree of Bachelor of I recommend the project to be forwarded to the examiner for

Pharmacy. evaluation.

Date:.. Place: Pune

Dr. B. S. Kuchekar Principal

CERTIFICATE
This is to certify that MR.RISHIKESH. D. CHAKOR has completed the project entitled DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ROSUVASTATIN IN TABLET DOSAGE FORM . under my supervision and guidance. He has collected the literature very sincerely and methodically and his work is authentic. I recommend the project to be forwarded to the examiner for evaluation. Date:.. Mr.V.P.Choudhari
Designation: Assistant Prof. (Pharmaceutical Analysis and Quality Assurance Department)

Place: Pune

DECLARATION

I, hereby declare that the dissertation entitled DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ROSUVASTATIN IN TABLET DOSAGE FORM . , is based on the work carried out in the laboratories of Maharashtra Institute of Pharmacy, Pune. This dissertation is now ready for examination Date: Place: Pune Signature of Student Name &

ACKNOWLEDGEMENT
The joyness, satisfaction and euphoria that come along with successful completion of any work would be incomplete unless we mention the people who made it possible whose constant guidance and encouragement served as a beam of light and crowed out efforts

I take this opportunity to thanks PROF. DR. B. S. KUCHEKAR, Principal, MAEERs, Maharashtra Institute of Pharmacy, for his continuous support and cooperation. I express my deep sense of gratitude to my Project Guide ASSISTANT PROF. (MR) V.
P. CHOUDHARI, Pharmaceutical Analysis and Quality Assurance Department, MAEERs,

Maharashtra Institute of Pharmacy for his help and support, for their valuable advice and encouragement which enabled me to complete this project.
I must place on my record very special thank to my friends for their charming company, timely help and co-operation.

A friend in need is a friend indeed and I am hereby thankful to my colleagues and friends for their constant encouragement and moral support.

Thanks

Rishikesh Chakor

INDEX
Chapter No. Particulars Page No.

1. 2. 3. 4. 5. 6.

ABSTRACT INTRODUCTION AIM AND OBJECTIVES PLAN OF WORK DRUG PROFILE MATERIAL AND INSTRUMENTS EXPERIMENTAL WORK (METHODS DEVELOPMENT) RESULT AND DISCUSSION CONCLUSION REFERNCES ERRATA

1 2-18 19 20 21-22 23 24-28

7. 8 9 10 11

29-35 36 37-38 39