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ClinicalQuestions

1)WhywouldtherebecauseforconcernifayoungpregnantmotherisRh-,herhusbandisRh+,andthisis theirsecondchild? Answer: IfthemotherwasgivenRhoGAMbeforeorshortlyafterthebirthofthefirstchild,thereislittle concern,becausetheRhoGAMpreventedthemotherfromsensitizingherselfagainstherchild.Ifshe didnottakeRhoGAM,thereisachancethesecondchildwilldeveloperythroblastosisfetalisanddie beforebirth.


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2)AtotalWBCcountandadifferentialWBCcounthavebeenorderedforMrs.Johnson.Whatinformationis obtainedfromthedifferentialcountthatthetotalcountdoesnotprovide? Answer: Thedifferentialcountdeterminestherelativeproportionofindividualleukocytetypes(avaluable diagnostictool).ThetotalWBCcountindicatesanincreaseordecreaseinnumberofWBCs.


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3)Listthreebloodteststhatmightbeorderedifanemiaissuspected. Answer: Thetestsforanemiaarehematocrit,completebloodcount,andmicroscopicstudyoferythrocytes.


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4)Apersoncomplainsofnoenergy,achronicsorethroat,alow-gradefever,andistiredandachy.Hisdoctor notesanenlargedspleenuponexamination.Whatdiagnosiswouldyouexpectandwhatdefinitivetest wouldyourequest? Answer: Thetestwouldbeadifferentialwhitebloodcellcounttolookforelevatednumbersofmonocytesand atypicallymphocytes.Thediagnosiswouldbepossibleinfectiousmononucleosis,pendingtestresults.


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5)AmanofMediterraneanancestrygoestohisdoctorwiththefollowingsymptoms.Heisverytiredallofthe time.Hehasdifficultycatchinghisbreathafterevenmildexercise.Hisdoctorordersthefollowingtests: CBC,hematocrit,differentialWBCcount.Thetestsshowimmatureerythrocytes,fragileerythrocytes,and lessthan2millionRBCspercubicmillimeter.Whatwouldbeatentativediagnosisandsuggestedtreatment? Answer: Thediagnosisisthalassemia.Thetreatmentisbloodtransfusion.


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6)A68-year-oldmaleisadmittedtothehospitalforemphysema.Heishypoxicandhislabsreveallowoxygen levels.Hishematocritis65%.Thephysicianhastoldhimthathehasatypeofpolycythemiainwhichhe hasanincreasednumberoferythrocytescirculatinginhisbloodstream.Theclienttellsthenursethathe doesnotunderstandwhatthatmeans.Howwouldthenurseexplainthisintermstheclientwould understand? Answer: Becauseyouhavedecreasedoxygenlevelsinyourblood,yourbodyhasrespondedbyproducing moreredbloodcells,causingatypeofpolycythemia.Thelowoxygenlevelstimulateserythropoietin productioninthekidneystostimulatemoreredbloodcells.


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7)Anelderlyclienttellsthenursethatshehasbeenverytiredlatelyandhasdifficultywalkingtohermailbox, withoutgettingveryshortofbreath.Thenursenotesthemucousmembranesarepale.Shestatessinceher husbanddiedthreemonthsago,shehasnotbeeneatingwell.Thephysicianconfirmsthatshehasirondeficiencyanemia.Howaretheclientsclinicalmanifestationsandirondeficiencyanemiarelated? Answer: Theclinicalmanifestationsaredirectlyattributedtothereductionintheamountofoxygenavailableto tissues.Anemicindividualsarefatigued,oftenpale,shortofbreath,andchilly.


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8)A17-year-oldblackmaleisadmittedtothehospitalinsickle-cellcrisis.Painmanagementisatoppriority forclientsinsickle-cellcrisis.Explainwhy. Answer: SicklecellanemiaresultsfromadefectivehemoglobinS-producinggenewhichcausesredbloodcells toroughenandbecomesickle-shaped.Suchsicklingcanproducehemolysis.Thealteredcellstendto pileupincapillariesandsmallerbloodvessels,makingthebloodmoreviscous.Normalcirculationis impaired,causingseverepainandswelling.


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9)A52-year-oldwomanwasdiagnosedwithleukemiaandhasbeenreceivingchemotherapyasanoutpatient. ShetellstheRNthatshehasntbeenfeelingwell.Thepatientsskiniswarmtotouchandshehasalowgradefeverof100.2F.Theneutrophilbloodcountislessthan1000/ul.Thenurseisconcernedaboutthe possibilityofinfectionbecauseoftheneutrapeniaandlow-gradefever.Explainwhy. Answer: Alow-gradefeverinsomeonewhohasneutropeniaisamajorconcernforsurvival.Neutropeniaisa concernbecauseoftheneutrophilsroleinphagocytosis.Thispatienthasadecreasedabilitytofight offinfection

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