Arellano University Legarda, Manila Submitted by: Trinidad, Czarina May V.

BSN III Section 3 NCM 102-RLE MS Ward Mr. Von Bacuyag July 18-19,25-26, 2011 Name of Patient: Mr. R. A. Age/Sex: 56 year old, male

Name of Drug Generic Name: Ceftriaxone Brand Name: Rocephin

Mechanism of Action -Inhibits bacterial cell wall synthesis, rendering cell wall osmotically unstable, leading to cell death

Adverse Reaction -Leukopenia, serum sickness, anaphylaxis.

Indication -Treatment of LRIT (e.g. bronchitis, pneumonia, bronchopneumonia, emphysema, lung abscess), skin and soft tissue infections. Pre-operative prophylaxis to reduce chance of postoperative surgical infections.

Contraindication -Hypersensitivity to cephalosporins and penicillins, lidocaine or any other local anaesthetic product of the amide type -Use with caution in patients with history of gastrointestinal disease. Nephrotoxicity has been reported following concomitant administration with aminoglycosides.

Side Effects: -Phlebitis, rash, diarrhea, vomiting.

Nursing Responsibilities -Instruct patient to take medication as prescribed for the length of time ordered even if he feels better. -Teach patient to report sore throat, bruising, bleeding and joint pain. -Advise patient to watch out for perineal itching, fever, malaise, redness, pain, swelling, rash diarrhea.

Classification: Antimicrobial and Antiparasitic Availability: Injection and Infusion

Name of drug

Mechanism of Action

Adverse Effects

Indication

Contraindication

Nursing Responsibilities -assess patients infection before and regularly throughout therapy -monitor renal, hepatic, and hematopoetic functions during prolonged therapy. -be alert for adverse reactions and drug interactions -if adverse GI reactions occurs, monitor patients hydration. -tell patient to take entire amount prescribed even after he feels better. -instruct patient to report diarrhea and to avoid selfthreatening psudomembranus colitis -tell patient receiving drug I.V. to report discomfort at infusion site.

Clindamycin ANTIBIOTIC; Anti- infectives

- inhibits bacterial protein synthesis by binding to 50S subunit of ribosome. - hinders or kills susceptible bacteria.

CNS: headache CV: Thrombophlebitis EENT: pharyngitis GI: abdominal pain, Anorexia, bloody or tarry stools, constipation, diarrhea, dysphagia, esophagitis, flatulence, nausea, psuedomembranus colitis, unpleasant or bitter taste, vomiting. GU: UTI HEMATOLOGIC: Eosinophilia, thrombocytopenia, transient leukopenia SKIN: maculopapular rash, urticaria OTHER: anaphylaxis, erythema, pain (I.V. use), induration, pain; sterile abcess (I.M. use)

- infections caused by sensitive staphylococci, streptococci, pneumococci, bacteroides, fusibacterium, clostridium perfringens, and other sensitive aerobic and anaerobic organisms. -endocarditis prophylaxis for dental procedures in patients allergic to penicillin -acne vulgaris -bacterial vaginosis - pneumocystis jiroveci (carinii) pneumonia -toxoplasmosis (cerebral or ocular) immunocompromise d patients

-contraindicated in patients hypersensitive to drug or lincomycin -use cautiously in patients with renal or hepatic disease, asthma, history of GI disease, or significant allergies.