Professional Documents
Culture Documents
Appendix
Research
Strategy
New Application
Background and
Significance
Research Strategy
a. Significance
Research Design and b. Innovation
c. Approach
Methods
Preliminary
Studies/Progress
Report
Preliminary
Studies for New
Applications
Progress Report
for
Renewal/Revision
Preliminary Studies
PIs preliminary studies, data and/or
experiences pertinent to the
application
Helps to establish likelihood of
success of proposed application
Preliminary Studies:
Strategies for Success
Describe research team expertise
this now goes in Biosketch
Dr. Insel and her co-investigators have been collaborating for the past
8 years in different capacities and participate in ongoing
communication. All have played an active role in developing the grant
application.
Preliminary Studies:
Strategies for Success
Organize PS by specific aim
Use consistent format for PS
studies
Concise presentation of PS findings
Use figures and tables to summarize PS
results (but make them reader friendly!)
a. Methotrexate
b. Control
GFAP positive cells per microscopic field were quantified. Results from the
Mann-Whitney Rank Sum Test showed that the median number of GFAP
positive cells per field was significantly greater in methotrexate treated
animals compared to controls (T = 1694, p <0.0001). Figure 2 below is a box
plot of GFAP positive cells per field in methotrexate treated (MTX) and control
animals.
Nuclei Enriched
Nuclei Depleted
Preliminary Studies:
Pitfalls to Avoid
Findings should be foundational for
proposed study or not included
Findings should not be redundant with
proposed study
Findings should be directly relevant to
proposed work and demonstrate how
findings guide further work