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JOURNAL IDENTITY
JOURNAL
IDENTITY
Title
Type
Prospective study
Researcher
INTRODUCTION
INTRODUCTI
ON
Micronutrient deficiencies contribute to impaired growth,
health, and development (Ladipo, 2000) and the relation between
maternal diet and the physical measurements of the new born
has been described
Associated with:
Pregnant woman
New born
MICRONUTRIE
NT
Deficiency
percentage of
nutrient in
pregnant
Effect to
anthropometry
new born baby
GOAL
Effects of
multivitamin dan
multimineral
supplement
Healthy
pregnant
woman
METHOD
Subject
A total of 100 apparently healthy women receiving prenatal
care between 12 and 16 weeks of gestation in the Obstetric
Departments of Grenoble and Lyon Hospitals in France
Treatmet
the supplement or the placebo from 1472 weeks of gestation
to delivery. The tablets were given out for 2 months, but with
the recommendation to return the residual blisters every
mont
METHOD
Supplementation
The subjects received a daily supplement containing vitamin
C (60 mg), b-carotene (4.8 mg), vitamin E (10 mg), thiamin
(1.4 mg), riboflavin (1.6 mg), niacin (15 mg), pantothenic acid
(6 mg), folic acid (200 mg), cobalamin (1 mg), Zn (15 mg as
citrate), Mg (87.5 mg as glycerophosphate), Ca (100 mg as
carbonate) or a placebo.
MICRONUTRIENT DETERMINATIONS
RESULTS
RESULT
S
Table 1. baseline characteristic of participating woman at enrolmant
DISCUSSION
DISCUSSI
ON
In this study:
As expected, the supplemental intake of vitamins was
efficient to improve significantly the blood levels of vitamin
E, C, b-carotenes, folic acid, B2 and B6
The study did not find statistical differences Effects of
micronutrients on pregnant women and newborn
In this study showed that:
DISCUSSION (2)
CONCLUSION
CONCLUSION
Concluded that:
This randomized double-blind study suggests
that the use of combined micronutriment
supplements, at nutritional doses, improved
babies birth weight and maternal biological
status. These preliminary results need to be
confirmed in larger further studies, but suggest
that optimal micronutrient nutrition should be
encouraged, not only in women with poor
nutritional status or in complicated
pregnancies, but also in apparently healthy
pregnant women, without any particular life
style risk
1.
Based on the journal that we read, we got new information that the
use of combined micronutriment supplements at nutritional doses
improved babies birth weight and maternal biological status, while
the number of infants with birth weights below 2700g was
significantly higher in placebo.
2.
3.
REFERENCES
REFERENCES
1. Arnaud J, Bellanger J, Bienvenu F, Chappuis P & Favier A (1986):
Recommended method for assaying serum zinc with flame atomic
absorption. Ann. Biol. Clin. Paris 44, 7787.
2. Arnaud J, Bellanger J, Chappuis P, Favier A & Galliot M (1985):
Recommendations for the assay of serum copper by flame atomic
absorption spectrometry. Ann. biol. Clin. 43, 297318.
3. Arnaud J, Fortis I, Blachier S, Kia D & Favier A (1991): Simultaneous
determination of retinol, a-tocopherol and b-carotene in serum by isocratic
high performance liquid chromatography. J. Chromatogr. 572, 103116.
4. Bates JH, Young S, Galway L, Traub AI & Hadden A (1997): Antioxidant
status and lipid peroxidation in diabetic pregnancy.
5. Br. J. Nutr. 78, 523532.
6. Bayoumi RA & Rosalki SB (1976): Evaluation of methods of coenzyme
activation of erythrocyte enzymes for detection of deficiency of Vitamins
B1, B2 and B6. Clin Chem 22, 327335.
REFERENCES(2)
7. Briefel RR, Bialostosky K, Kennedy-Stephenson J, McDowell MA,
Ervin RB & Wright JD (2000): Zinc intake of the U.S. Population:
findings from the third National Health and Nutrition Examination Survey, 19881994. J. Nutr. 130S, 1367S1373S.
8. Brown KH, Peerson JM & Allen LH (1998): Effect of zinc supplementation on childrens growth: a meta-analysis of intervention
trials. Bibl. Nutr. Dieta 54, 7683.
9. Cargnoni AA, Gregorini G, Ceconi C, Maiorca R & Ferrari R
(1994): Lipid peroxidation in normal pregnancy and preeclampsia.
Adv. Exp. Med. Biol. 336, 42034207.
10. Cederberg J, Siman CM & Eriksson UJ (2001): Combined
treatment with vitamin E and vitamin C decreases oxidative stress
and improves fetal outcome in experimental pregnancy. Pediatr.
Res. 49, 755762.
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