Derema

melanoma
:Risk factors
Sun light.most important
Albinism
On top of begnin nevus, DYSPLASTIC NEVI
, FH)+(
:Criteria of malignancy
A..asymmetry
B..border irregularity
C..color irregularities
Ddiameter more than 6 mm
E.Change in the apperance
 melanoma
Most imp prognostic factor..depth
:Spread
Local
LN
Distantbrain and liver.black
spots
Biopsyexcisional biopsy
 :Melanoma

:TTT
Surgery.main line of ttt in all
stages
If u remove and the margin contains
malignant cellsreexcise
If wide spreadinterferon
 Basal cell carcinoma
Most common skin cancer
Locally malignant tumour..no distant spread
Main risk factor..sunlight
Most common siteface
Waxy lesion that shing like a pearl
Biopsy.shave biopsy( biopsy with 2mm margin)
:TTT
SURGERY
VERY RADIOSENSITIVE
If the margin are + for malignant cells after
excision..re excise
Rodent Ulcer
( BCC)
Basal Cell Carcinoma
 SCC
:RF
Radiation
Eldery
Actinic keratosis
Keratoacanthoma
Bowens disease
leukoplaia
Chronic osteomyelitis
Burn..marjolin ulcer
Inv..excisional biopsy
TTT.surgery is the main ttt
If spread..radiation
 scc
Carcinoma of lower lip..SCC
Carcinoma of tongueSCC
Carcinoma of esophagus.SCC
Carcinoma of marjolin ulcer.SCC
Carcinoma of chronic osteomyelitis
SCC
 Mohs surgery
The best choice for Basal cell
carcinoma of the lid
Save the tissues
Can be used for SCC
Kaposi sarcoma
Most common cause.AIDS
Site.skin( most common), GIT, lung
Organism.HSV8
Only AIDS aquired by sex is associated
with KS
:TTT
Antiretroviral..main ttt
Interferon and vinctristine
chemo
 Seborrheic keratosis
Ageold
Sitehead, neck, back, trunk
Shape..stuck on apperance
Malignant transformation.noooo
TTTcosmetic removal
 Seborrheic
dermatitis(dandruff)
Shape. scaly, flaky, itchy, and red skin
Age.kids
If extensive disease in adult suspect HIV
If extensive disease in old suspect
PARKINSONISM
,TTT antifungals
, corticosteroids topical
keratolytics
 ACTINIC KERATOSIS
Main PF..SUN EXPOSURE
AGEUSUALLY OLD
, dark or light, tan, pink, red
Central scales
.Growthslowly
RISK..MALIGNANCYSCC
TTTremoval
 keratoacanthoma
Key word.rapid progression
Main risk factor.sun exposure
Premalignant leisionSCC
dome-shaped, symmetrical,
surrounded by a smooth wall of
inflamed skin
TTT.REMOVAL
Atopic Dermatitis
Heriditary disorder Hx of asthma, allergic
rhinitis, rash
Ageless than 5 ys
.+Family history
Usually along cheeks, face, trunk
Dry and papular rash, scratching makes it
worselichenified
Most common site in children.flexures
( antecubital fossa)
Cp..severe itching
Aggravated by stress, anxiety, dry conditions
 Atopic dermatitis
Tx: good lotions & rehydration of skin
Avoid soap
Cotton is less irritating
:Drugs
Topical cortisone
Tacrolimus
Antihistaminics
Antibiotics with secondary infection
 Eczema herpeticum
Fatal
Herpes simplex infection on top of
atopic dermatitis
Main cpvesicles
TTTacyclovir