NANO

IMMUNOSENSOR
 Aim
To develop a prototype of nano
immunosensor for the detection of a
prostate cancer biomarker osteopontin
using Carbon Nanotube Field Effect
Transistor.
 Objectives:

To utilize excellent sensitivity and

selectivity of Carbon nanotube field
effect transistor (CNTFET) biosensors for
detection of PSA for prostate cancer.
To fabricate simple, cost-effective,
high sensitive and high selectivity
immunosensor that can detect a
biomarker protein.
Idea/ Product/Innovation

Current Status:
Delayed Diagnosis of prostate cancer
Enzyme-linked immunosorbent assay
(ELISA)- commonly used method
pure samples,
long processing time,
special equipment and
trained personnel
Advantages:
Diagnosed prostate cancer in initial stages
itself.
It is high sensitivity and high selectivity bio
sensor.
Cost effective.
Miniature in size.
A CNT-FET based biosensor-showed a
detection limit of 30fM of osteopontin (OPN)
for prostate cancer.
Point of Care
Testing
Schematic of the transparent SWCNT
based immunosensors for OPN
detection
 Methodology

Steps to be followed for

fabrication
Preparation of glass
substrate .
Alignment of the CNT as
channel by dielectrophoresis
(DEP) (for OPN attachment
and detection).
Monoclonal antibodies
specific to OPN are
covalently immobilized on
the CNT surfaces.
source and drain electrodes
are developed at the ends.
Metallization is done for
contacts. STRUCTURE OF PROPOSED
PROTOTYPE
(Transparent SWCNT FET based
immunosensors for OPN
Scope
 Budget
THE FINANCIAL REQUIREMENT (may not be
restricted to DST support)

The cost of purchase of raw materials -

Rs.45,000/-

The cost of contingencies -

Rs.64,000/-

Product development cost/ Consultancy cost and

-Rs.65,500/-

Any other expenditure

-Rs.75,500/-
 Team along with mentor

Name of Mentor : Dr. P.Geetha

Details of student members:

S.N Name of Student Qualificati Year E-mail-Id
o on, MobileNo
Branch
1. K.Vamsi B.Tech, III vamsikrishnak 7799864880
Krishna ECE dmr@gmail.co
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2. M.DilipKumar B.Tech, III dilipshiva11@ 9014346911
ECE gmail.com
3. K.Supraja B.Tech, III Supraja2597 9515920488
ECE @gmail.com
4. M.V.Padmini B.Tech, III padduammulu 9652132424
ECE tpt@gmail.co
m