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Chest Pain
• Transduction: Nociceptors
• Transmission: A-delta, C fiber
• Perception
• Modulation
Physiology of Pain
Transmission
Transduction
nociceptor Spinal cord Brain stem Thalamus
Modulation
Definition
• Pain, pressure, tightness, or other discomfort originating in or
radiating to the chest
• constitutes an important indicator of potentially serious cardiac
or cardiovascular disorders.
• Pain: described as dull, heavy, or crushing, Sharp, stabbing,
or burning pain.
Origin
• Pain may originate from several different structures:
• within the chest:
o the skin o Heart
o Ribs o Lung
o intercostal muscles o Aorta
o pleura o Diaphragm
o esophagus o thoracic vertebrae
• Psychic origin
• Inflamation
• Ischemic-anoxic tissue
• Metabolic disturbance of tissue
• Tissue damage
• Trauma
• Inflamation
• Infection
• Ischemic-anoxic tissue
Pathophysiology of heart pain