& Liong, Henen Faith U. BSOT-3 Alcohol abuse is commonly called alcoholism. Symptoms of alcohol: -violent behavior -feelings of depression -hallucinations and delusions(rare) Long term: -intense alcohol adaptation of the body that has a withdrawal syndrome like: *insomnia *hyperactivity of the Autonomic N.S. *anxiety Epidemiology: * Race & Ethnicity -Whites have the highest rate of alcohol use. * Gender -Men are much more likely than women to be binge drinkers and heavy drinkers. * Region and Urbanicity -Alcohol use is highest in western states and lowest in southern states. * Education -70% of adults w/ college degrees are current drinkers compared w/ only 40% of those with less than a high school education. * Socioeconomic Class -Alcohol-related disorders appear among persons of all socioeconomic classes. Comorbidity: -Psychiatric diagnoses are most commonly associated w/ alcohol-related disorders. • Psychiatric Diagnosis includes: 1.) Anti-Social Personality Disorder -common in men w/ alcohol related disorders and can precede the development of alcohol related disorders. 2.) Mood Disorders -common in women than in men -occurs in patients w/ alcohol related disorders who have a high daily consumption of alcohol and family history of alcohol abuse -they are the ones at risk of suicide -bipolar 1 disorders are prone to be developing alcohol related disorders due to they’re manic episodes. 3.) Anxiety Disorders -People use alcohol for it’s efficacy in alleviating anxiety Etiology: • Factors that are responsible for the development of Alcohol-related disorders: 1.) Psychological theories -Alcohol helps decrease feelings of nervousness and helps in coping in day to day stresses of life. *low doses of alcohol: enhanced feeling of well- being. * high doses of alcohol: nervousness and tension increased. 2.) Psychodynamic Theories -People uses alcohol because it helps them deal w/ self-punitive harsh superegos and to decrease unconscious stress levels. -Also it helps relieve frustrations. 3.) Behavioral Theories -Alcohol may have rewarding effects after intake w/c is called subsequent reinforcement that it contributes to the decision to drink again and again because it becomes an important aspect in alcoholic rehabilitation. 4.) Socio-cultural Theories -Alcohol is influenced by social groups that have high and low rates of alcoholism -less influence of ethnic groups, less prone to alcoholism -more influence of ethnic groups, more prone to alcoholism ALCOHOL-RELATED DISORDERS: • Alcohol Dependence and Alcohol Abuse Diagnosis: -In DSM-IV-TR, It is the need for daily use of large amounts of alcohol for adequate functioning, a regular pattern of heavy alcohol intake. -The drinking pattern is associated with certain behaviors: *inability to cut down or stop drinking *continuation of drinking despite a serious physical disorder *persons w/ alcohol dependence and alcohol abuse show impaired social or occupational functioning because of alcohol use *Alcohol *Alcohol Intoxication Withdrawal - Evidence of ingestion - May include seizures of ethanol. and autonomic - Evidence of hyperactivity. behavioral changes, a - Withdrawal symptoms slowing in motor include fatigue, performance and a malnutrition, physical decrease in the ability illness and to think clearly. depression. • Delirium Diagnosis: - Patients with recognized alcohol withdrawal symptoms should be carefully monitored to prevent progression to alcohol withdrawal delirium, the most severe form of the withdrawal syndrome. - Alcohol withdrawal delirium is a medical emergency that can result in significant morbidity and mortality. - Patients with delirium are in danger to themselves and to others because they may be assaultive or suicidal. - If untreated, it will result to medical illnesses such as pneumonia, heart failure, etc. • Alcohol-Induced Persisting Amnestic Disorder Diagnosis: - In DSM-IV-TR, it is a disturbance in short-term memory caused by prolonged heavy use of alcohol, usually occurs in persons who have been drinking heavily for many years. • Alcohol-Induced Psychotic Disorder
Diagnosis: - Includes delusions and hallucinations
- The most common hallucinations are auditory,
usually voices, but are often unstructured. - Hallucinations after alcohol withdrawal are considered rare and the syndrome is distinct from alcohol withdrawal delirium, usually appear in persons abusing alcohol for a long time. • Alcohol-Induced Anxiety Disorder Diagnosis: - Symptoms includes anxiety, panic attacks, obsessive-compulsive symptoms or phobic symptoms; can either be during intoxication or during withdrawal. • Fetal Alcohol Syndrome Diagnosis: - Indicates that women who are pregnant or are breast-feeding should not drink alcohol. - The leading cause of mental retardation in US, occurs when mothers drinking alcohol expose fetuses to alcohol in utero, the alcohol inhibits intrauterine growth and postnatal development. - Microcephaly, craniofacial malformations, and limb and heart defects are commonin affected infants; development of maladaptive behaviors. - It may also cause hormone imbalances that increase the risk of abnormalities Prognosis: - Between 10 to 40% of alcoholic persons enter some kind of formal treatment program during the course of their alcohol problems. - First, is the absence of preexisting antisocial personality disorder - Second, evidence of general life stability with a job, continuing family contacts and the absence of severe legal problems. - Third, if the patient stays for the full course of the initial rehabilitation (2 to 4 weeks). Treatment and Rehabilitation: - 3 steps: • Intervention
- the goal of the intervention step is called
confrontation, is to break through feelings of denial and help the patient recognize the consequences likely to occur if disorder is not treated. - also a process aimed at maximizing the motivation for treatment. • Detoxification
- 1st step: is through physical examination; absence of
serious medical disorder, severe alcohol withdrawal is unlikely. - 2nd step: is to offer rest, adequate nutrition and multiple vitamins. • Rehabilitation - 3 major components: • Continued efforts to increase and maintain high levels of motivation for abstinence. • Work to help the patient readjust to a lifestyle free of alcohol. • Relapse prevention. Medications: - Benzodiazephines- primary medication to control alcohol withdrawal symptoms such as seizure activity, delirium, anxiety, and tremor associated with alcohol withdrawal. Preparations: - major amphetamines that are currently used in the US are dextroamphetamine, methamphetamine, a mixed destroamphetamine- amphetamine salt and the amphetamine-like compound methylphenidate; these drugs have street names such as ice, crystal meth and speed. - In general class, amphetamines are referred as analeptics, stimulants and psychostimulants used to increase performance and to induce a euphoric feeling such as: students studying for exams, athletes in competition, etc. - Amphetamine-like substances are ephedrine, pseudophedrine and phenylpropanolamine; these drugs are very dangerous and can cause death. Epidemiology: * Race and Ethnicity -increasing among white professionals. * Age -highest rates of use were among 18-25 year olds followed by 12-17 year olds. * Socio-economic Class -Amphetamine-related disorders appear among persons of all socioeconomic classes. Neuropharmacology: - Amphetamines may be taken orally or inhaled (“snorting”). - Designer amphetamines causes release of dopamine and norepinephrine and serotoni, the neurotransmitter implicated as the major neurochemical pathway for hallucinogens. Disorders: Amphetamine Dependence and Amphetamine • Abuse Diagnosis: - In the DSM-IV-TR, it can result in a rapid downward spiral of a person’s abilities to cope with work and family related obligations and stresses. *Amphetamine *Amphetamine intoxication withdrawal
- Intoxication of - Crash occurs with
cocaine and symptoms of anxiety, amphetamines are dysphoric mood, similar because it has fatigue, etc. been strongly - Most serious influenced by withdrawal symptom cocaine. is depression which is - Amphetamine associated with specifies perceptual suicidal ideation. disturbances. • Amphetamine Intoxication Delirium Diagnosis: - Delirium associated with amphetamine use generally results from high doses of amphetamine and so sleep deprivation affects the clinical presentation. - The use of amphetamines by a person with preexisting brain damage can also cause development of delirium. • Amphetamine-Induced Psychotic Disorder Diagnosis: - Presence of paranoia. - Visual hallucinations and evidence of disordered thinking - Treatment of choice is the short-term use of an antipsychotic medication such as Haldol. • Amphetamine-Induced Mood Disorder Diagnosis: - intoxication is associated with manic or mixed mood features, whereas withdrawal is associated with depressive mood features.
• Amphetamine-Induced Anxiety Disorder
Diagnosis: - Amphetamine, like cocaine, can induce symptoms similar to those seen in obsessive- compulsive disorder, panic disorder and phobic disorders. • Other Agents: - “CLUB DRUGS”- use in clubs, bars, parties; includes GHB, ketamine, ecstasy, rohypnol (date rape drugs), etc. that produces disorienting and sedating effects and often users cannot recall what occurred during all or part of an episode under the influence of the drug. Treatment and Rehabilitation: - An inpatient setting and the use of multiple therapeutic methods are usually necessary to achieve lasting abstinence. - Treatment with specific drugs may be needed on short-term basis and antipsychotics may also be prescribed for a few days but physicians must also establish a therapeutic alliance with patients to deal with underlying depression. Preparations: - Cannabis are obtained from the Indian hemp plant, Cannabis sativa and is the most commonly used illicit drug in the US. - Cannabis plant is usually cut, dried, chopped and rolled into cigarettes and which are then smoked. - Common names of Cannabis includes: marijuana, grass, pot, weed, tea and Mary Jane. Epidemiology: *Race and Ethnicity - whites had higher rates of lifetime and past- year marijuana use than blacks. *Age - aged 18 years or older had used marijuana at least once in their life-time. - adolescents in school indicates recent increases in lifetime, annual, current and daily use of marijuana by 8th and 10th graders. *Gender - current marijuana use in males was almost twice the rate for females overall among those aged 26 and older. Neuropharmacology: - When cannabis is smoked, the euphoric effects appear within minutes, peak in about 30 mins. And last 2-4 hours. - It may be taken orally when it is prepared with food, such as brownies and cakes. - Cannabis must be taken orally or may also be taken by inhaling its smoke. Disorders: • Cannabis Dependence and Cannabis Abuse Diagnosis: - Psychological dependence on cannabis use does develop in long-term users. *Cannabis Intoxication - Heightens users’ sensitivities to external stimuli. - For 8 to 12 hours after using cannabis, users’ impaired motor skills interfere with the operation of motor vehicles and other heavy machinery. • Cannabis Intoxication Delirium Diagnosis: - Is characterized by marked impairment on cognition and performance task. - Modest doses impair memory, reaction time, perception, motor coordination and attention but high doses also impair users’ level of consciousness. • Cannabis-Induced Anxiety Disorder Diagnosis: - Short-lived anxiety states often provoked by paranoid thoughts. - Panic attacks may be induced, based on ill- defined and disorganized fears. • Cannabis-Induced Psychotic Disorder Diagnosis: - It is rare; transient paranoid ideation is more common. - Psychotic episodes are sometimes referred to as “hemp insanity”. • Cannabis-Related Disorder Diagnosis: *flashbacks-persons who have experienced sensations related to cannabis intoxication after the short-term effects of the substance have disappeared. *cognitive impairment-longer periods of heavy cannabis use, the more pronounced the cognitive impairment. *amotivational syndrome-associated with long- term heavy use and has been characterized by a person’s unwillingness to persist in a task be it at school, work, or in any setting that requires prolonged attention or tenacity. Treatment and Rehabilitation: Principles: 1.) Abstinence- can be achieved through direct interventions such as hospitalization. 2.) Support- can be achieved through the use of individual, family and group psychotherapies. Medical use of Marijuana: - Marijuana has been used as a medicinal herb for centuries. - Used to treat various disorders such as multiple sclerosis(MS), chronic pain, AIDS, epilepsy and glaucoma.