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Short Loop
Ultra-Short
Loop
Synthesis Storage Release
Oxytocin ADH/AVP
Gq/10
Oxytocin protein
coupled
receptors
• @ Target cells:
Activates PLC → Increase IP3 & 1,2 DAG → Increase
Cytosolic Ca2+ → Contraction of Smooth muscle cells
Estrogen, Progesterone
Opiates, Nicotine